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The map label for this gene is fruR [H]

Identifier: 238922443

GI number: 238922443

Start: 17878

End: 18621

Strand: Direct

Name: fruR [H]

Synonym: EUBREC_0017

Alternate gene names: 238922443

Gene position: 17878-18621 (Clockwise)

Preceding gene: 238922441

Following gene: 238922444

Centisome position: 0.52

GC content: 38.98

Gene sequence:

>744_bases
ATGCTGGCAGAAGATAGATGCAAAAAAATACTCGATATATTAGATTCGATGGGAAGTGTGACTGTTCAGCAGCTTATGGA
TGAGCTTGATACATCCGAGTCAACAATCAGACGTGATCTGGTTGCAATGGACAAGAAGGGTTATCTCACCAAGGTACATG
GTGGTGCGATTGTAAATAATACGAATATCCATACTCAGGATGAGAAGGTTATCAACAGGCTTAAGCAGAATCGCAACGAA
AAGGAACAGATTGCCAGATATGCGGCATCACTTATTGTGGATAATGATTTTGTTTATATAGATGCCGGTACTACAACAGC
AGTCATGATTGATTATATTACTGCAAAGAATGTGGTTTTTGTTACAAACTCTCTGACTAATGCCAAGAGAATTTCCGATA
GGGGATATACAGTATATATTCTGGGTGGCGAGTTCAAGTCTACTACCGAGGCTATTGTCGGAGATGAGGCCGTTGTGACG
CTCGATAAATATAATTTTACGAAGGGCTTCTGGGGAACCAACGGAATTACTGTGAAGAATGGATTTACGACTCCGGAGAT
AAAGGAGGCCATGGTTAAAAAGAAATCCATGGAGAATAGCAAGGAGAAATACATTCTTGCGGATGACAGTAAGTTTTCAC
AGGTATCAAGCATCAAGTTTGCTGATTTTGAAGATGCTGTAATTATTACAAATGCACTAAGTAATGACAACTATAAGAAA
TACAAAAATATTAAGGAGGTCTAA

Upstream 100 bases:

>100_bases
ATGAATGTTGAAATGTTTAATACAGTAATTTGAAAATAAGCATTGAATAAATGGCTTATAAAATAAGTCTTTGAATAATT
TGATAAACTGGGGTGATTAG

Downstream 100 bases:

>100_bases
CATGATTTACACAGTTACTTTTAATCCATCATTAGATTATATTGTTGATGTAACAGATTTTAAGACAGGAGTAGTCAATA
GAACGACTGGAGAGAAGATT

Product: transcription repressor of fructose operon FruR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MLAEDRCKKILDILDSMGSVTVQQLMDELDTSESTIRRDLVAMDKKGYLTKVHGGAIVNNTNIHTQDEKVINRLKQNRNE
KEQIARYAASLIVDNDFVYIDAGTTTAVMIDYITAKNVVFVTNSLTNAKRISDRGYTVYILGGEFKSTTEAIVGDEAVVT
LDKYNFTKGFWGTNGITVKNGFTTPEIKEAMVKKKSMENSKEKYILADDSKFSQVSSIKFADFEDAVIITNALSNDNYKK
YKNIKEV

Sequences:

>Translated_247_residues
MLAEDRCKKILDILDSMGSVTVQQLMDELDTSESTIRRDLVAMDKKGYLTKVHGGAIVNNTNIHTQDEKVINRLKQNRNE
KEQIARYAASLIVDNDFVYIDAGTTTAVMIDYITAKNVVFVTNSLTNAKRISDRGYTVYILGGEFKSTTEAIVGDEAVVT
LDKYNFTKGFWGTNGITVKNGFTTPEIKEAMVKKKSMENSKEKYILADDSKFSQVSSIKFADFEDAVIITNALSNDNYKK
YKNIKEV
>Mature_247_residues
MLAEDRCKKILDILDSMGSVTVQQLMDELDTSESTIRRDLVAMDKKGYLTKVHGGAIVNNTNIHTQDEKVINRLKQNRNE
KEQIARYAASLIVDNDFVYIDAGTTTAVMIDYITAKNVVFVTNSLTNAKRISDRGYTVYILGGEFKSTTEAIVGDEAVVT
LDKYNFTKGFWGTNGITVKNGFTTPEIKEAMVKKKSMENSKEKYILADDSKFSQVSSIKFADFEDAVIITNALSNDNYKK
YKNIKEV

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=221, Percent_Identity=32.1266968325792, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787540, Length=221, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789519, Length=247, Percent_Identity=27.1255060728745, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI226510968, Length=236, Percent_Identity=27.5423728813559, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789829, Length=211, Percent_Identity=27.4881516587678, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790635, Length=242, Percent_Identity=28.099173553719, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788069, Length=224, Percent_Identity=26.7857142857143, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787063, Length=252, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790753, Length=216, Percent_Identity=23.1481481481481, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87082344, Length=220, Percent_Identity=24.0909090909091, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27720; Mature: 27720

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEDRCKKILDILDSMGSVTVQQLMDELDTSESTIRRDLVAMDKKGYLTKVHGGAIVNN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCEEEEC
TNIHTQDEKVINRLKQNRNEKEQIARYAASLIVDNDFVYIDAGTTTAVMIDYITAKNVVF
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHEECCCEEEEECCCCEEEEEEEEECCCEEE
VTNSLTNAKRISDRGYTVYILGGEFKSTTEAIVGDEAVVTLDKYNFTKGFWGTNGITVKN
EECCCCCHHHHCCCCEEEEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEC
GFTTPEIKEAMVKKKSMENSKEKYILADDSKFSQVSSIKFADFEDAVIITNALSNDNYKK
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCEEECCCCCEEEEEECCCCCCHHH
YKNIKEV
HHHHCCC
>Mature Secondary Structure
MLAEDRCKKILDILDSMGSVTVQQLMDELDTSESTIRRDLVAMDKKGYLTKVHGGAIVNN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCEEEEC
TNIHTQDEKVINRLKQNRNEKEQIARYAASLIVDNDFVYIDAGTTTAVMIDYITAKNVVF
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHEECCCEEEEECCCCEEEEEEEEECCCEEE
VTNSLTNAKRISDRGYTVYILGGEFKSTTEAIVGDEAVVTLDKYNFTKGFWGTNGITVKN
EECCCCCHHHHCCCCEEEEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEC
GFTTPEIKEAMVKKKSMENSKEKYILADDSKFSQVSSIKFADFEDAVIITNALSNDNYKK
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHCEEECCCCCEEEEEECCCCCCHHH
YKNIKEV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]