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The map label for this gene is fruK [H]

Identifier: 238922444

GI number: 238922444

Start: 18623

End: 19540

Strand: Direct

Name: fruK [H]

Synonym: EUBREC_0018

Alternate gene names: 238922444

Gene position: 18623-19540 (Clockwise)

Preceding gene: 238922443

Following gene: 238922445

Centisome position: 0.54

GC content: 40.74

Gene sequence:

>918_bases
ATGATTTACACAGTTACTTTTAATCCATCATTAGATTATATTGTTGATGTAACAGATTTTAAGACAGGAGTAGTCAATAG
AACGACTGGAGAGAAGATTTTTGCAGGTGGTAAAGGCATCAATGTTTCCATGGTTCTTAAGAATCTTGGAATGAGCAATA
CTTCACTTGGTTTTACAGCGGGTTTTACAGGAAATGAAATTAAAAGACTTCTAGCAAAAAAAGGTGTTGATACTGATTTT
ATAGAGGTGGAGGATGGTATTTCACGTATCAACGTGAAGCTTCGCTCAAATGAGGAATCCGAGATTAATGGTCAGGGTCC
TGCAATCACTGAGGACAATATTAAAAAACTCTATGAGAAGCTTGACTGCTTAAAGGAGTCTGATGTGCTTGTTCTCGCAG
GAAGTATTCCTGATGTGATGCCTTCATCAATGTATATGGATATCATGAAGCATCTTGAGGGTCGCGGAATAAATATCGTG
GTTGATGCGACAAGAAATCTGCTCACAAACGTGCTTCCATATAAGCCGTTCCTCATCAAGCCAAACAATCATGAGCTCGG
TGAGATATTCGGGGTTGAGATTACAGACAAGGACGATGTGATAAAGTATGCAAAGAAGCTTCAGGAGCAGGGCGCAAGAA
ACGTGCTTGTTTCAATGGCAGGCGACGGAGCAGTGCTTGTGACTGAGGATGGACAGGAGTTTAAGGCAAATGCACCTAAA
GGAAAGCTCAAAAATTCTGTAGGAGCAGGAGATTCGATGGTAGCCGGATTTGTTTACGGATACCTCAAATCAAATGATTA
TAAGCAGGCATTTATTTATGGCGTATGTACGGGAAGTGCAAGTGCATTTTCTGAGGAGCTTGCTACAAAGCCTGAGGTTG
AAGCACTTATTGATAAATGGGACAGTGCTTCCAATTAA

Upstream 100 bases:

>100_bases
TCAAGCATCAAGTTTGCTGATTTTGAAGATGCTGTAATTATTACAAATGCACTAAGTAATGACAACTATAAGAAATACAA
AAATATTAAGGAGGTCTAAC

Downstream 100 bases:

>100_bases
ACAAACGGTATCAAAAAGGTTGATATAAATAATTAAATTAATACATTCTATTAGGAGGAATGATGTATGACAATCAGGGA
TTTATTGGCAGCTGAGAGTA

Product: fructose-1-phosphate kinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MIYTVTFNPSLDYIVDVTDFKTGVVNRTTGEKIFAGGKGINVSMVLKNLGMSNTSLGFTAGFTGNEIKRLLAKKGVDTDF
IEVEDGISRINVKLRSNEESEINGQGPAITEDNIKKLYEKLDCLKESDVLVLAGSIPDVMPSSMYMDIMKHLEGRGINIV
VDATRNLLTNVLPYKPFLIKPNNHELGEIFGVEITDKDDVIKYAKKLQEQGARNVLVSMAGDGAVLVTEDGQEFKANAPK
GKLKNSVGAGDSMVAGFVYGYLKSNDYKQAFIYGVCTGSASAFSEELATKPEVEALIDKWDSASN

Sequences:

>Translated_305_residues
MIYTVTFNPSLDYIVDVTDFKTGVVNRTTGEKIFAGGKGINVSMVLKNLGMSNTSLGFTAGFTGNEIKRLLAKKGVDTDF
IEVEDGISRINVKLRSNEESEINGQGPAITEDNIKKLYEKLDCLKESDVLVLAGSIPDVMPSSMYMDIMKHLEGRGINIV
VDATRNLLTNVLPYKPFLIKPNNHELGEIFGVEITDKDDVIKYAKKLQEQGARNVLVSMAGDGAVLVTEDGQEFKANAPK
GKLKNSVGAGDSMVAGFVYGYLKSNDYKQAFIYGVCTGSASAFSEELATKPEVEALIDKWDSASN
>Mature_305_residues
MIYTVTFNPSLDYIVDVTDFKTGVVNRTTGEKIFAGGKGINVSMVLKNLGMSNTSLGFTAGFTGNEIKRLLAKKGVDTDF
IEVEDGISRINVKLRSNEESEINGQGPAITEDNIKKLYEKLDCLKESDVLVLAGSIPDVMPSSMYMDIMKHLEGRGINIV
VDATRNLLTNVLPYKPFLIKPNNHELGEIFGVEITDKDDVIKYAKKLQEQGARNVLVSMAGDGAVLVTEDGQEFKANAPK
GKLKNSVGAGDSMVAGFVYGYLKSNDYKQAFIYGVCTGSASAFSEELATKPEVEALIDKWDSASN

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=264, Percent_Identity=33.7121212121212, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1788017, Length=289, Percent_Identity=29.757785467128, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 33161; Mature: 33161

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTVTFNPSLDYIVDVTDFKTGVVNRTTGEKIFAGGKGINVSMVLKNLGMSNTSLGFTA
CEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCEEE
GFTGNEIKRLLAKKGVDTDFIEVEDGISRINVKLRSNEESEINGQGPAITEDNIKKLYEK
CCCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
LDCLKESDVLVLAGSIPDVMPSSMYMDIMKHLEGRGINIVVDATRNLLTNVLPYKPFLIK
HHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCEEEC
PNNHELGEIFGVEITDKDDVIKYAKKLQEQGARNVLVSMAGDGAVLVTEDGQEFKANAPK
CCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHCCCCCC
GKLKNSVGAGDSMVAGFVYGYLKSNDYKQAFIYGVCTGSASAFSEELATKPEVEALIDKW
CHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHC
DSASN
CCCCC
>Mature Secondary Structure
MIYTVTFNPSLDYIVDVTDFKTGVVNRTTGEKIFAGGKGINVSMVLKNLGMSNTSLGFTA
CEEEEEECCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCEEE
GFTGNEIKRLLAKKGVDTDFIEVEDGISRINVKLRSNEESEINGQGPAITEDNIKKLYEK
CCCHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
LDCLKESDVLVLAGSIPDVMPSSMYMDIMKHLEGRGINIVVDATRNLLTNVLPYKPFLIK
HHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCCCCEEEC
PNNHELGEIFGVEITDKDDVIKYAKKLQEQGARNVLVSMAGDGAVLVTEDGQEFKANAPK
CCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHCCCCCC
GKLKNSVGAGDSMVAGFVYGYLKSNDYKQAFIYGVCTGSASAFSEELATKPEVEALIDKW
CHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHC
DSASN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]