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The map label for this gene is fumB [H]

Identifier: 238922441

GI number: 238922441

Start: 9844

End: 10395

Strand: Direct

Name: fumB [H]

Synonym: EUBREC_0009

Alternate gene names: 238922441

Gene position: 9844-10395 (Clockwise)

Preceding gene: 238922439

Following gene: 238922443

Centisome position: 0.29

GC content: 39.31

Gene sequence:

>552_bases
ATGGAAAAACATATAACAACTCCAATCACACAGAAAATAACAAAAGACCTGAGATCAGGAGACTATGTATACATAACAGG
TGAAATGTATGTGGCAAGAGATGCTGCACACAAAAGAATGATAGAGGCGCTGGACCGTAAAGAAGAACTGCCAATAGATA
TAAAGGATTCGACAATCTACTATATGGGACCATCACCGGCCAGAGATGGACGTCCAATTGGCTCAGCCGGACCTACAACA
GCAACAAGAATGGACAAATATGCCCCAAGACTGCTTGATTTAGGTGAAAAAGCAATGATTGGCAAAGGAAAAAGATCAAA
AGAAGTAATAGATGCAGTCATTCGCAATAAAGCAGTGTATTTTGCCGCAGTCGGTGGAGCAGGCGCTCTCCTTTCAAAAT
GCATAAAATCATCAGAAGTAATCTGCTATGATGATCTCGGTGCAGAGGCAATAAGAAAGATATACGTAGAAGATTTCCCG
GTAATTGTGGTAATAGACAGTGAAGGAAACAATCTGTACGAGACTTCAATAAAAGAATTTAAAAAAATATAA

Upstream 100 bases:

>100_bases
AGTGAAATGTGAAGTGTAATTAAAAAGCTATAATTGTTACAGGTTATATTATGCTGGAAAAATAAAAATACAGTAAAAAT
AAAAGAATCAGGAGAAAAAA

Downstream 100 bases:

>100_bases
AAATACTATTGACAAAACAAAGAAAATTTTATAGAATAAACAATGCGTCACGTAAGTGCGTAAAACATTTAAATAATTTA
TGTAAAGACTTTGGAGAAGT

Product: fumarate hydratase subunit B

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MEKHITTPITQKITKDLRSGDYVYITGEMYVARDAAHKRMIEALDRKEELPIDIKDSTIYYMGPSPARDGRPIGSAGPTT
ATRMDKYAPRLLDLGEKAMIGKGKRSKEVIDAVIRNKAVYFAAVGGAGALLSKCIKSSEVICYDDLGAEAIRKIYVEDFP
VIVVIDSEGNNLYETSIKEFKKI

Sequences:

>Translated_183_residues
MEKHITTPITQKITKDLRSGDYVYITGEMYVARDAAHKRMIEALDRKEELPIDIKDSTIYYMGPSPARDGRPIGSAGPTT
ATRMDKYAPRLLDLGEKAMIGKGKRSKEVIDAVIRNKAVYFAAVGGAGALLSKCIKSSEVICYDDLGAEAIRKIYVEDFP
VIVVIDSEGNNLYETSIKEFKKI
>Mature_183_residues
MEKHITTPITQKITKDLRSGDYVYITGEMYVARDAAHKRMIEALDRKEELPIDIKDSTIYYMGPSPARDGRPIGSAGPTT
ATRMDKYAPRLLDLGEKAMIGKGKRSKEVIDAVIRNKAVYFAAVGGAGALLSKCIKSSEVICYDDLGAEAIRKIYVEDFP
VIVVIDSEGNNLYETSIKEFKKI

Specific function: It functions in the generation of fumarate for use as an anaerobic electron acceptor [H]

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1790564, Length=157, Percent_Identity=42.6751592356688, Blast_Score=130, Evalue=4e-32,
Organism=Escherichia coli, GI1787897, Length=152, Percent_Identity=43.421052631579, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1789443, Length=185, Percent_Identity=31.8918918918919, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646
- InterPro:   IPR004647
- InterPro:   IPR011167
- InterPro:   IPR020557 [H]

Pfam domain/function: PF05681 Fumerase; PF05683 Fumerase_C [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 20296; Mature: 20296

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKHITTPITQKITKDLRSGDYVYITGEMYVARDAAHKRMIEALDRKEELPIDIKDSTIY
CCCCCCCHHHHHHHHHHCCCCEEEEECCEEEHHHHHHHHHHHHHCCHHCCCEEECCCEEE
YMGPSPARDGRPIGSAGPTTATRMDKYAPRLLDLGEKAMIGKGKRSKEVIDAVIRNKAVY
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHCCEEE
FAAVGGAGALLSKCIKSSEVICYDDLGAEAIRKIYVEDFPVIVVIDSEGNNLYETSIKEF
EEEECCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHH
KKI
HCC
>Mature Secondary Structure
MEKHITTPITQKITKDLRSGDYVYITGEMYVARDAAHKRMIEALDRKEELPIDIKDSTIY
CCCCCCCHHHHHHHHHHCCCCEEEEECCEEEHHHHHHHHHHHHHCCHHCCCEEECCCEEE
YMGPSPARDGRPIGSAGPTTATRMDKYAPRLLDLGEKAMIGKGKRSKEVIDAVIRNKAVY
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHCCEEE
FAAVGGAGALLSKCIKSSEVICYDDLGAEAIRKIYVEDFPVIVVIDSEGNNLYETSIKEF
EEEECCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHH
KKI
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2656658; 7610040; 9278503 [H]