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The map label for this gene is ttdA [C]

Identifier: 238922439

GI number: 238922439

Start: 8836

End: 9681

Strand: Direct

Name: ttdA [C]

Synonym: EUBREC_0007

Alternate gene names: 238922439

Gene position: 8836-9681 (Clockwise)

Preceding gene: 238922438

Following gene: 238922441

Centisome position: 0.26

GC content: 43.14

Gene sequence:

>846_bases
ATGATCAGGGAAATAAACGTTTCAGAAATAACAGCTGCAATAAAGGAAATGTGCATACAGGCAAATCATTTTCTTTCGCC
GGACATGGACAAGGCACTTAAAGCTGCAACAGCAAATGAAGAATCACCTTTAGGTAAAAAAATATTAAACCAGCTACAGG
AAAACTTAAAAATAGCAGGCGAGGATATGATACCGATATGTCAGGATACCGGAATGGCAGTTTTTTTCATAGAAATAGGC
CAGGATGTCCATTTTACGGGAGGCGTATTGGAGGATGCCATAAATGAAGGAGTCAGACAGGGCTACACAGACGGCTATCT
GAGAAAATCAGTGGTAAAGGATCCGCTCATCAGGGAAAATACAAAGGACAACACACCTGCAGTCATCCATTACTCAATAG
TTTCCGGCGACAAGGTCAAAATAACCTTTGCACCAAAGGGTTTTGGAAGCGAAAACATGAGTCGTGTATTTATGTTAAAG
CCGGCAGATGGTATAGAGGGAGTAAAAAATGCGATTCTGACAGCAGTTTCAGATGCAGGGCCAAACGCATGTCCTCCTAT
GGTTGTCGGAGTCGGAGTCGGTGGAACCTTTGAAAAATGCGCAATAATGGCAAAAAAAGCGCTGACAAGAGAAGCAGGCA
CACATTCAGACATAGAGTATGTGGCAGAGCTTGAAAAAGAGATGCTTGAAAAAATTAATAATCTGGGTATAGGGCCCGGA
GGACTCGGCGGAAGCACTACTGCCCTCGCAGTAAACATAAACACATATCCAACCCACATTGCAGGATTGCCGGTTGCGGT
AAATATTTGCTGTCATGTAAACCGCCATGTAGTGAAGGAATTGTAA

Upstream 100 bases:

>100_bases
AATAAATATGTTTATCCACAAAAACACAAAAAATAATATTGAATTGTGGATAAAAGGTGCCGGAATTTAAAATACAGAGA
ATAAAAAGAGAGGAAAAGAA

Downstream 100 bases:

>100_bases
AGAATTACTGCATAGAAGAAGAAAGAAAGTGGCAATTTTAATTGTTACAGCTATAGTGAAATAGTGAAATGTGAAGTGTA
ATTAAAAAGCTATAATTGTT

Product: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MIREINVSEITAAIKEMCIQANHFLSPDMDKALKAATANEESPLGKKILNQLQENLKIAGEDMIPICQDTGMAVFFIEIG
QDVHFTGGVLEDAINEGVRQGYTDGYLRKSVVKDPLIRENTKDNTPAVIHYSIVSGDKVKITFAPKGFGSENMSRVFMLK
PADGIEGVKNAILTAVSDAGPNACPPMVVGVGVGGTFEKCAIMAKKALTREAGTHSDIEYVAELEKEMLEKINNLGIGPG
GLGGSTTALAVNINTYPTHIAGLPVAVNICCHVNRHVVKEL

Sequences:

>Translated_281_residues
MIREINVSEITAAIKEMCIQANHFLSPDMDKALKAATANEESPLGKKILNQLQENLKIAGEDMIPICQDTGMAVFFIEIG
QDVHFTGGVLEDAINEGVRQGYTDGYLRKSVVKDPLIRENTKDNTPAVIHYSIVSGDKVKITFAPKGFGSENMSRVFMLK
PADGIEGVKNAILTAVSDAGPNACPPMVVGVGVGGTFEKCAIMAKKALTREAGTHSDIEYVAELEKEMLEKINNLGIGPG
GLGGSTTALAVNINTYPTHIAGLPVAVNICCHVNRHVVKEL
>Mature_281_residues
MIREINVSEITAAIKEMCIQANHFLSPDMDKALKAATANEESPLGKKILNQLQENLKIAGEDMIPICQDTGMAVFFIEIG
QDVHFTGGVLEDAINEGVRQGYTDGYLRKSVVKDPLIRENTKDNTPAVIHYSIVSGDKVKITFAPKGFGSENMSRVFMLK
PADGIEGVKNAILTAVSDAGPNACPPMVVGVGVGGTFEKCAIMAKKALTREAGTHSDIEYVAELEKEMLEKINNLGIGPG
GLGGSTTALAVNINTYPTHIAGLPVAVNICCHVNRHVVKEL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=273, Percent_Identity=29.6703296703297, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790564, Length=288, Percent_Identity=29.1666666666667, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787897, Length=249, Percent_Identity=32.1285140562249, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30060; Mature: 30060

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREINVSEITAAIKEMCIQANHFLSPDMDKALKAATANEESPLGKKILNQLQENLKIAG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECC
EDMIPICQDTGMAVFFIEIGQDVHFTGGVLEDAINEGVRQGYTDGYLRKSVVKDPLIREN
CCCCCEECCCCCEEEEEEECCCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCC
TKDNTPAVIHYSIVSGDKVKITFAPKGFGSENMSRVFMLKPADGIEGVKNAILTAVSDAG
CCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
PNACPPMVVGVGVGGTFEKCAIMAKKALTREAGTHSDIEYVAELEKEMLEKINNLGIGPG
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GLGGSTTALAVNINTYPTHIAGLPVAVNICCHVNRHVVKEL
CCCCCCEEEEEEECCCCCHHCCCCCEEHHHHHCCHHHHHCC
>Mature Secondary Structure
MIREINVSEITAAIKEMCIQANHFLSPDMDKALKAATANEESPLGKKILNQLQENLKIAG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECC
EDMIPICQDTGMAVFFIEIGQDVHFTGGVLEDAINEGVRQGYTDGYLRKSVVKDPLIREN
CCCCCEECCCCCEEEEEEECCCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCC
TKDNTPAVIHYSIVSGDKVKITFAPKGFGSENMSRVFMLKPADGIEGVKNAILTAVSDAG
CCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
PNACPPMVVGVGVGGTFEKCAIMAKKALTREAGTHSDIEYVAELEKEMLEKINNLGIGPG
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GLGGSTTALAVNINTYPTHIAGLPVAVNICCHVNRHVVKEL
CCCCCCEEEEEEECCCCCHHCCCCCEEHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]