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The map label for this gene is add [H]

Identifier: 238922267

GI number: 238922267

Start: 463275

End: 464363

Strand: Reverse

Name: add [H]

Synonym: EUBELI_20502

Alternate gene names: 238922267

Gene position: 464363-463275 (Counterclockwise)

Preceding gene: 238922269

Following gene: 238922266

Centisome position: 74.09

GC content: 39.67

Gene sequence:

>1089_bases
ATGTCAGATAATAATATGTTAGAGGGTGTTTTTTTGAATAACAGTAATATAGAATGGATAGAAAAACTGGATTGCCTTAC
AGACCTGCATGTACATCTTGATGGTTCACTGTCGCTTGAATCTGTAAGACATCTTTGCGGTATGCAGAATATAGAAACAG
GTGATGATGCAGAATTGTCAGCGAAGCTGAGTGTATCATCAGATTGTAAGAATCTTAATGAATACCTTGAAAAATTCGAG
TTTCCACTTCAGCTTTTACAGACACATGAGGCTGTTAAATATAGTGTGTGTCAGCTTATTAAGGAGCAGGAAGAACAGGG
AGTAATATACAGCGAGATAAGATTTGCACCACAGCTTCATACAAGAAAAGGATTGTCACAGCAGGAGATTGTTGAAGCAG
CATGTGAGGGACTTGATGAATCAAGAAAGTACTGGAAGTCATATTCCTGTCACAATCTTATATTATGCTGTATGCGTTCG
GATGATAATAAGGATGCTAATATGGAGACAGTAAGACTTGCTGCATTATATGCTGAAAAGGGAAGAGGTGTTGTGGCAGC
AGACCTTGCAGGAGCAGAAGGACTTTATGCAACTGATACATTTGCTGATGTATTCAGGGATGCAGTGCAGAAAGGAGTGC
CATTTACTATTCACGCAGGCGAGGCAGCCGGAGCGGAAAGTGTTAAATGTGCATTGAATTTTCAGGCTGTAAGAATAGGA
CATGGCGTAAGATGTACAGAGAATCCTTTAGTTATGCAGGAGCTTGCAGACAGAGAGACTGCATTGGAATTATGTCCGAC
AAGCAATCTGAATACTAAAATATATGAGACAATAAAGGACTATCCGATACAGCAGCTTATGAATAAGGGGATAAAGGTTA
CTGTTAATACGGATAATATGATGGTTTCTAACACTACAGAGGCGAGGGAACTTGCATTGGTTGCAGATACATTTAATATG
GAGAAGAAAGATGTTAAGAAGCTGATAATGAATGGTGTTGAAGCTGCATTTACAACAGAGGGAATAAAAAACCGCTTAAG
GGCAAGAGTGGATACACAGTTTGCCAAAGTGGCTGGAATCAGAGGTTAG

Upstream 100 bases:

>100_bases
ATTAATCATAAAATTTATCATAATACTTGGTAAAATATGGATGTAAAGCCTTATCGGTGTTGCAAATATACTCAATGCAG
TTTAAAATATAATGAAGTGT

Downstream 100 bases:

>100_bases
GGTATGAATGAAGTTAATGAATTATTTACTAAAGAAAATGTAGAAAAGATATATGTTCCGGATATTGTTAAGGACGATTT
GCTAAGTATTATAGAAGAAA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSDNNMLEGVFLNNSNIEWIEKLDCLTDLHVHLDGSLSLESVRHLCGMQNIETGDDAELSAKLSVSSDCKNLNEYLEKFE
FPLQLLQTHEAVKYSVCQLIKEQEEQGVIYSEIRFAPQLHTRKGLSQQEIVEAACEGLDESRKYWKSYSCHNLILCCMRS
DDNKDANMETVRLAALYAEKGRGVVAADLAGAEGLYATDTFADVFRDAVQKGVPFTIHAGEAAGAESVKCALNFQAVRIG
HGVRCTENPLVMQELADRETALELCPTSNLNTKIYETIKDYPIQQLMNKGIKVTVNTDNMMVSNTTEARELALVADTFNM
EKKDVKKLIMNGVEAAFTTEGIKNRLRARVDTQFAKVAGIRG

Sequences:

>Translated_362_residues
MSDNNMLEGVFLNNSNIEWIEKLDCLTDLHVHLDGSLSLESVRHLCGMQNIETGDDAELSAKLSVSSDCKNLNEYLEKFE
FPLQLLQTHEAVKYSVCQLIKEQEEQGVIYSEIRFAPQLHTRKGLSQQEIVEAACEGLDESRKYWKSYSCHNLILCCMRS
DDNKDANMETVRLAALYAEKGRGVVAADLAGAEGLYATDTFADVFRDAVQKGVPFTIHAGEAAGAESVKCALNFQAVRIG
HGVRCTENPLVMQELADRETALELCPTSNLNTKIYETIKDYPIQQLMNKGIKVTVNTDNMMVSNTTEARELALVADTFNM
EKKDVKKLIMNGVEAAFTTEGIKNRLRARVDTQFAKVAGIRG
>Mature_361_residues
SDNNMLEGVFLNNSNIEWIEKLDCLTDLHVHLDGSLSLESVRHLCGMQNIETGDDAELSAKLSVSSDCKNLNEYLEKFEF
PLQLLQTHEAVKYSVCQLIKEQEEQGVIYSEIRFAPQLHTRKGLSQQEIVEAACEGLDESRKYWKSYSCHNLILCCMRSD
DNKDANMETVRLAALYAEKGRGVVAADLAGAEGLYATDTFADVFRDAVQKGVPFTIHAGEAAGAESVKCALNFQAVRIGH
GVRCTENPLVMQELADRETALELCPTSNLNTKIYETIKDYPIQQLMNKGIKVTVNTDNMMVSNTTEARELALVADTFNME
KKDVKKLIMNGVEAAFTTEGIKNRLRARVDTQFAKVAGIRG

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=340, Percent_Identity=26.1764705882353, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI226693318, Length=349, Percent_Identity=23.2091690544413, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787910, Length=329, Percent_Identity=27.9635258358663, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17538512, Length=345, Percent_Identity=28.695652173913, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32565969, Length=345, Percent_Identity=28.695652173913, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324188, Length=345, Percent_Identity=22.0289855072464, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24645260, Length=326, Percent_Identity=25.7668711656442, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 40302; Mature: 40171

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNNMLEGVFLNNSNIEWIEKLDCLTDLHVHLDGSLSLESVRHLCGMQNIETGDDAELS
CCCCCEEEEEEEECCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCCCCCCCCCCEE
AKLSVSSDCKNLNEYLEKFEFPLQLLQTHEAVKYSVCQLIKEQEEQGVIYSEIRFAPQLH
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHH
TRKGLSQQEIVEAACEGLDESRKYWKSYSCHNLILCCMRSDDNKDANMETVRLAALYAEK
HHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHC
GRGVVAADLAGAEGLYATDTFADVFRDAVQKGVPFTIHAGEAAGAESVKCALNFQAVRIG
CCCEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEEEEEEEC
HGVRCTENPLVMQELADRETALELCPTSNLNTKIYETIKDYPIQQLMNKGIKVTVNTDNM
CCCEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHCCEEEEEECCCE
MVSNTTEARELALVADTFNMEKKDVKKLIMNGVEAAFTTEGIKNRLRARVDTQFAKVAGI
EEECCCCHHHEEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RG
CC
>Mature Secondary Structure 
SDNNMLEGVFLNNSNIEWIEKLDCLTDLHVHLDGSLSLESVRHLCGMQNIETGDDAELS
CCCCEEEEEEEECCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCCCCCCCCCCEE
AKLSVSSDCKNLNEYLEKFEFPLQLLQTHEAVKYSVCQLIKEQEEQGVIYSEIRFAPQLH
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHH
TRKGLSQQEIVEAACEGLDESRKYWKSYSCHNLILCCMRSDDNKDANMETVRLAALYAEK
HHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHC
GRGVVAADLAGAEGLYATDTFADVFRDAVQKGVPFTIHAGEAAGAESVKCALNFQAVRIG
CCCEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEEEEEEEC
HGVRCTENPLVMQELADRETALELCPTSNLNTKIYETIKDYPIQQLMNKGIKVTVNTDNM
CCCEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHCCEEEEEECCCE
MVSNTTEARELALVADTFNMEKKDVKKLIMNGVEAAFTTEGIKNRLRARVDTQFAKVAGI
EEECCCCHHHEEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA