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The map label for this gene is cqsS [H]

Identifier: 238922265

GI number: 238922265

Start: 461044

End: 461445

Strand: Reverse

Name: cqsS [H]

Synonym: EUBELI_20500

Alternate gene names: 238922265

Gene position: 461445-461044 (Counterclockwise)

Preceding gene: 238922266

Following gene: 238922263

Centisome position: 73.63

GC content: 38.31

Gene sequence:

>402_bases
GTGACAGTAGAAAGCAGAGGGAAAATAATGAACAAATGTGTTCTTGTAGTTGATGATAATGATTTTAACAGGGAACTTGT
GAGAGATATTCTTGAAGATGAGGATATTGTTGTTTATGAGGCAGCAGATGGTAAATCTGCAGTTGATTTCATGGAGTCAC
AGGATGGTACAAATGTTAATGCAATTCTTATGGATTTAAGAATGCCTGTTATGGACGGTATGGAGGCAACAAGAGTCATA
AGACAGGGGAGCAGAGGAAGTGTACCTATAATAGCAATGACAGCTAATTCATTTGAAACTGATAAGGATTATGTACATGC
TAATGGAATGAACGGATTTATTGCAAAGCCCATAGATGTTGCAACATTGGCAGAGCAGATAGGAGAAATGGCAGGGTGGT
AA

Upstream 100 bases:

>100_bases
TTGAAGTTATTAAGGTTGAAAAGAGAAAATACTGGAATGAGAATGGCTGCAGGGCATACAGAAGAAAGCTTGTTTCAGAA
ATAAGAGAGAATAATGTACT

Downstream 100 bases:

>100_bases
TACACCCTGCCATTTCTCCTATCTTGAATCACCCATAAAGAAAAGGGCAACTGTTCCAGGACCTGAATGCGTTCCTATTG
TAGGACATATATAATTAATC

Product: hypothetical protein

Products: NA

Alternate protein names: Cholerae quorum-sensing sensor [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTVESRGKIMNKCVLVVDDNDFNRELVRDILEDEDIVVYEAADGKSAVDFMESQDGTNVNAILMDLRMPVMDGMEATRVI
RQGSRGSVPIIAMTANSFETDKDYVHANGMNGFIAKPIDVATLAEQIGEMAGW

Sequences:

>Translated_133_residues
MTVESRGKIMNKCVLVVDDNDFNRELVRDILEDEDIVVYEAADGKSAVDFMESQDGTNVNAILMDLRMPVMDGMEATRVI
RQGSRGSVPIIAMTANSFETDKDYVHANGMNGFIAKPIDVATLAEQIGEMAGW
>Mature_132_residues
TVESRGKIMNKCVLVVDDNDFNRELVRDILEDEDIVVYEAADGKSAVDFMESQDGTNVNAILMDLRMPVMDGMEATRVIR
QGSRGSVPIIAMTANSFETDKDYVHANGMNGFIAKPIDVATLAEQIGEMAGW

Specific function: Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to luxU and luxO [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=107, Percent_Identity=36.4485981308411, Blast_Score=60, Evalue=5e-11,
Organism=Escherichia coli, GI145693157, Length=114, Percent_Identity=29.8245614035088, Blast_Score=60, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=108, Percent_Identity=38.8888888888889, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 14648; Mature: 14517

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
7.5 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVESRGKIMNKCVLVVDDNDFNRELVRDILEDEDIVVYEAADGKSAVDFMESQDGTNVN
CCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCE
AILMDLRMPVMDGMEATRVIRQGSRGSVPIIAMTANSFETDKDYVHANGMNGFIAKPIDV
EEEEEHHCCHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCEECCCHH
ATLAEQIGEMAGW
HHHHHHHHHHCCC
>Mature Secondary Structure 
TVESRGKIMNKCVLVVDDNDFNRELVRDILEDEDIVVYEAADGKSAVDFMESQDGTNVN
CCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCE
AILMDLRMPVMDGMEATRVIRQGSRGSVPIIAMTANSFETDKDYVHANGMNGFIAKPIDV
EEEEEHHCCHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCEECCCHH
ATLAEQIGEMAGW
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA