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The map label for this gene is infC [H]

Identifier: 238922263

GI number: 238922263

Start: 459348

End: 459842

Strand: Reverse

Name: infC [H]

Synonym: EUBELI_20498

Alternate gene names: 238922263

Gene position: 459842-459348 (Counterclockwise)

Preceding gene: 238922265

Following gene: 238922262

Centisome position: 73.37

GC content: 39.39

Gene sequence:

>495_bases
ATGATTAACGAACAGATCAGATGCAAAGAGGTTCGTGTTATTGGAGAAGAAGGACAGCAGCTTGGAGTTATGGCATCAAG
AGATGCTTTAAACATGGCTAAGGATGCAGGAGTTGATTTAGTAATGGTTTCACCATCAGCTAACCCACCTGTATGCAGAA
TTGTAGATTATGGCAAGTTCAAGTACGAACAGCTCCGCAAGGAAAAGGAAGCTAAGAAGAAGCAGAAGACAGTAGAAGTT
AAGGAAGTTCGTTTATCACCCAACATCGATGTCAATGACCTTAACACTAAGTGTAATTCAGCAAGAAAGTTCATTGAAAA
AGGTAACAAGGTTAAAGTATCATTAAGATTCAGAGGAAGAGAGATGGCTCATATCGATTCCACTAAGCATATTCTGGAAG
ACTTTGCAGAGAAGCTTAGCGATATAGCAGTAATTGAGAAGGCTCCTAAGATGGAAGGCAGGAGCATGATGATGTTTTTA
ACTGAAAAACGTTAA

Upstream 100 bases:

>100_bases
TTACACATAATATTAGGATTGTGTTTTGATTAAAGAAAGTGGATAGCTATGCTATTCACTTTAATTTTTTATATGGGGGT
GTACCGCTATTAACGAGTTA

Downstream 100 bases:

>100_bases
AATAAATAACAATTAACAGGTATTTTTAGGAGGATTATTATGCCAAAGGTAAAGACAAAAAGAGCAGCTGCAAAGCGTTT
TAAAGTAACTGGAACAGGTA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MINEQIRCKEVRVIGEEGQQLGVMASRDALNMAKDAGVDLVMVSPSANPPVCRIVDYGKFKYEQLRKEKEAKKKQKTVEV
KEVRLSPNIDVNDLNTKCNSARKFIEKGNKVKVSLRFRGREMAHIDSTKHILEDFAEKLSDIAVIEKAPKMEGRSMMMFL
TEKR

Sequences:

>Translated_164_residues
MINEQIRCKEVRVIGEEGQQLGVMASRDALNMAKDAGVDLVMVSPSANPPVCRIVDYGKFKYEQLRKEKEAKKKQKTVEV
KEVRLSPNIDVNDLNTKCNSARKFIEKGNKVKVSLRFRGREMAHIDSTKHILEDFAEKLSDIAVIEKAPKMEGRSMMMFL
TEKR
>Mature_164_residues
MINEQIRCKEVRVIGEEGQQLGVMASRDALNMAKDAGVDLVMVSPSANPPVCRIVDYGKFKYEQLRKEKEAKKKQKTVEV
KEVRLSPNIDVNDLNTKCNSARKFIEKGNKVKVSLRFRGREMAHIDSTKHILEDFAEKLSDIAVIEKAPKMEGRSMMMFL
TEKR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=50.609756097561, Blast_Score=154, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18728; Mature: 18728

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEQIRCKEVRVIGEEGQQLGVMASRDALNMAKDAGVDLVMVSPSANPPVCRIVDYGKF
CCCCCCCHHHEEEECCCCCEECEEECCHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCH
KYEQLRKEKEAKKKQKTVEVKEVRLSPNIDVNDLNTKCNSARKFIEKGNKVKVSLRFRGR
HHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCC
EMAHIDSTKHILEDFAEKLSDIAVIEKAPKMEGRSMMMFLTEKR
EEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MINEQIRCKEVRVIGEEGQQLGVMASRDALNMAKDAGVDLVMVSPSANPPVCRIVDYGKF
CCCCCCCHHHEEEECCCCCEECEEECCHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCH
KYEQLRKEKEAKKKQKTVEVKEVRLSPNIDVNDLNTKCNSARKFIEKGNKVKVSLRFRGR
HHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCC
EMAHIDSTKHILEDFAEKLSDIAVIEKAPKMEGRSMMMFLTEKR
EEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]