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The map label for this gene is ykoW [H]

Identifier: 238922051

GI number: 238922051

Start: 233717

End: 235408

Strand: Reverse

Name: ykoW [H]

Synonym: EUBELI_20286

Alternate gene names: 238922051

Gene position: 235408-233717 (Counterclockwise)

Preceding gene: 238922052

Following gene: 238922049

Centisome position: 37.56

GC content: 39.3

Gene sequence:

>1692_bases
GTGATTAATGATATATTTAAATTATTTGGAGAGAAGGCAGCTGATATTTTATTTGAGATCATTACAGAATGTATGGACGA
TTATCTGTATATATTTGATCTGCAGAATAATACCTTTGAGATTTCACAGTCAGCTGTGGAACGATTTAATATACCGAGTA
ATATCCTGACAGATATGTCAAATGAAGTTATGAATGTAGTATATGAAGAAGACCGTGAGATGCTTGCAAAGCATCTTGCG
GATATATGTGAAGGAAGAGAAATGGTACATAATCTTCATTATAGATGGCTTGATAAAGAAGGTATGCCGGTATGGATCAA
CAGCCGTGGTATCGTTGTCAATGATCAGCAGGGAAATGCAGAGTATCTGGTCGGGTGTCTGAATGAGACCGGCAACAAGA
GAAGGGCTGATAATGTCACCGGACTGCTTGGCGGTCCGGAATTCCTTGCTTACTTGCGTGCACAAAAAGAACCCATTACC
AAGGGGTTTTTTATGCATATAGGAATTGATGATTTTGGAGCGATCAATAGCTCCAGGGGAGCTGATTATGGTAATTATAT
CCTGAAAAGCGTAGCCGGTTGCATGAAGGAATGCCTTTCAGACAAGCAGAGAATTTACCATCTGGTAGCGGATCAGTATG
TGATCGTGGATCTGGAAGCTTCCTCCGCAGAAGAAGCTGTGGCACTGAAAGAAAAGATTACAGATAAACTTCATAATTTC
ATAGTAGACGAAAATTATGAGGCTATATTTTCTATTTCTATTGGTGTTATAGATGCAGCAACATTTTGTGAGGGAACCGA
AGAATGCCGCAAAAAGTTTGAATTTGCCTTGAAACAGGCAAAAAGCATGGGTAAAAATGGATTCTATATTTTTGACCAGG
ATGACTATGAGGTCTTTTTACAACAAGGAAGAATCATAGCAACACTTCGTAATGCTATTGTGAACCATTATGATGGCTTT
GAAGTATACTACCAGCCGATCGTGGACTGTCAGTCCGAACAGATTATTGGAGCAGAGGCACTGATGCGTTTTTCCATGAT
AACGGAAGAAGGGCGGGAGTTTGTTTCACCGGTGGAGTTTATCCCATTATTGGAAGAGACCGGATTAATCATTCCCGCTG
GAAGATATATTTTGAACGAAGCTGCAGCAATGTGCTGTGAAATGCAGAAATATATTCCTGATTTCCGGATGAATGTAAAT
GTATCCTATGTTCAGATCCTGCAAGGCAATGTGGAGCGGGATATTCTGGATGCAATTCAAAAATATTCATTACAGCCGGA
ATGCTTATGTGTTGAAATGACAGAAAGCGGATTTATGGATATGACACCTTCGTTCTGTAAATTCCGTAAAACTCTGGACA
AGAACGGGATTCCCTTTGTGATCGATGATTTTGGAACAGGATATTCGAATCTTCATTGTATCCGTGATATGAATCCAAGT
TACGTGAAAATGGATAGGGATTTTACTGACAAGGCGATGAACAGTGACAGGGATTATGAATTATATAAAAATATCATCAC
CATGGTACATAGTATTAACGTCAGGATATGCGCAGAAGGCATCGAGGAAAAAGAATGGCTTCTGAAAATGAAAGAAATGA
AGGTTGATTATCTGCAAGGATATTATTTGGGAAGACCATGTGGAAAGAAACAGTTTCTGCAGCAATATGCCAGTGGCATC
AACATTAAATAA

Upstream 100 bases:

>100_bases
GCAGAGGGAGCAGCCAAGATGCATGACCGCGTGAATATTTTTAAGTTATTCTAGAAAATGACAGGAATAGAGTGAAGTAT
TCATAAGGAAGGTTATTGTT

Downstream 100 bases:

>100_bases
AGAAAGTAAGGCAGACTCAGCTATGTGAGGCTGCCTTATTTTATGTGCGAAGTTTGAGTTATAAAGAAAAAGGTATTAAA
TATTAGAATTAAGTGCTACA

Product: two-component system, PleD related family, response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MINDIFKLFGEKAADILFEIITECMDDYLYIFDLQNNTFEISQSAVERFNIPSNILTDMSNEVMNVVYEEDREMLAKHLA
DICEGREMVHNLHYRWLDKEGMPVWINSRGIVVNDQQGNAEYLVGCLNETGNKRRADNVTGLLGGPEFLAYLRAQKEPIT
KGFFMHIGIDDFGAINSSRGADYGNYILKSVAGCMKECLSDKQRIYHLVADQYVIVDLEASSAEEAVALKEKITDKLHNF
IVDENYEAIFSISIGVIDAATFCEGTEECRKKFEFALKQAKSMGKNGFYIFDQDDYEVFLQQGRIIATLRNAIVNHYDGF
EVYYQPIVDCQSEQIIGAEALMRFSMITEEGREFVSPVEFIPLLEETGLIIPAGRYILNEAAAMCCEMQKYIPDFRMNVN
VSYVQILQGNVERDILDAIQKYSLQPECLCVEMTESGFMDMTPSFCKFRKTLDKNGIPFVIDDFGTGYSNLHCIRDMNPS
YVKMDRDFTDKAMNSDRDYELYKNIITMVHSINVRICAEGIEEKEWLLKMKEMKVDYLQGYYLGRPCGKKQFLQQYASGI
NIK

Sequences:

>Translated_563_residues
MINDIFKLFGEKAADILFEIITECMDDYLYIFDLQNNTFEISQSAVERFNIPSNILTDMSNEVMNVVYEEDREMLAKHLA
DICEGREMVHNLHYRWLDKEGMPVWINSRGIVVNDQQGNAEYLVGCLNETGNKRRADNVTGLLGGPEFLAYLRAQKEPIT
KGFFMHIGIDDFGAINSSRGADYGNYILKSVAGCMKECLSDKQRIYHLVADQYVIVDLEASSAEEAVALKEKITDKLHNF
IVDENYEAIFSISIGVIDAATFCEGTEECRKKFEFALKQAKSMGKNGFYIFDQDDYEVFLQQGRIIATLRNAIVNHYDGF
EVYYQPIVDCQSEQIIGAEALMRFSMITEEGREFVSPVEFIPLLEETGLIIPAGRYILNEAAAMCCEMQKYIPDFRMNVN
VSYVQILQGNVERDILDAIQKYSLQPECLCVEMTESGFMDMTPSFCKFRKTLDKNGIPFVIDDFGTGYSNLHCIRDMNPS
YVKMDRDFTDKAMNSDRDYELYKNIITMVHSINVRICAEGIEEKEWLLKMKEMKVDYLQGYYLGRPCGKKQFLQQYASGI
NIK
>Mature_563_residues
MINDIFKLFGEKAADILFEIITECMDDYLYIFDLQNNTFEISQSAVERFNIPSNILTDMSNEVMNVVYEEDREMLAKHLA
DICEGREMVHNLHYRWLDKEGMPVWINSRGIVVNDQQGNAEYLVGCLNETGNKRRADNVTGLLGGPEFLAYLRAQKEPIT
KGFFMHIGIDDFGAINSSRGADYGNYILKSVAGCMKECLSDKQRIYHLVADQYVIVDLEASSAEEAVALKEKITDKLHNF
IVDENYEAIFSISIGVIDAATFCEGTEECRKKFEFALKQAKSMGKNGFYIFDQDDYEVFLQQGRIIATLRNAIVNHYDGF
EVYYQPIVDCQSEQIIGAEALMRFSMITEEGREFVSPVEFIPLLEETGLIIPAGRYILNEAAAMCCEMQKYIPDFRMNVN
VSYVQILQGNVERDILDAIQKYSLQPECLCVEMTESGFMDMTPSFCKFRKTLDKNGIPFVIDDFGTGYSNLHCIRDMNPS
YVKMDRDFTDKAMNSDRDYELYKNIITMVHSINVRICAEGIEEKEWLLKMKEMKVDYLQGYYLGRPCGKKQFLQQYASGI
NIK

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081921, Length=434, Percent_Identity=25.5760368663594, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=30.9322033898305, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787541, Length=393, Percent_Identity=22.1374045801527, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI87081845, Length=226, Percent_Identity=27.4336283185841, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI226510982, Length=379, Percent_Identity=25.065963060686, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786507, Length=246, Percent_Identity=27.6422764227642, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=29.5833333333333, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081980, Length=243, Percent_Identity=27.5720164609054, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787055, Length=226, Percent_Identity=29.2035398230088, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1788502, Length=236, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788849, Length=230, Percent_Identity=24.7826086956522, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082096, Length=195, Percent_Identity=25.6410256410256, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 64583; Mature: 64583

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDIFKLFGEKAADILFEIITECMDDYLYIFDLQNNTFEISQSAVERFNIPSNILTDMS
CCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHH
NEVMNVVYEEDREMLAKHLADICEGREMVHNLHYRWLDKEGMPVWINSRGIVVNDQQGNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCEEEEECCCCCH
EYLVGCLNETGNKRRADNVTGLLGGPEFLAYLRAQKEPITKGFFMHIGIDDFGAINSSRG
HHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCC
ADYGNYILKSVAGCMKECLSDKQRIYHLVADQYVIVDLEASSAEEAVALKEKITDKLHNF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
IVDENYEAIFSISIGVIDAATFCEGTEECRKKFEFALKQAKSMGKNGFYIFDQDDYEVFL
HCCCCCEEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
QQGRIIATLRNAIVNHYDGFEVYYQPIVDCQSEQIIGAEALMRFSMITEEGREFVSPVEF
HCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHH
IPLLEETGLIIPAGRYILNEAAAMCCEMQKYIPDFRMNVNVSYVQILQGNVERDILDAIQ
HHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCEECCCHHHHEEHHCCCHHHHHHHHH
KYSLQPECLCVEMTESGFMDMTPSFCKFRKTLDKNGIPFVIDDFGTGYSNLHCIRDMNPS
HCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCC
YVKMDRDFTDKAMNSDRDYELYKNIITMVHSINVRICAEGIEEKEWLLKMKEMKVDYLQG
EEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCC
YYLGRPCGKKQFLQQYASGINIK
EECCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MINDIFKLFGEKAADILFEIITECMDDYLYIFDLQNNTFEISQSAVERFNIPSNILTDMS
CCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHH
NEVMNVVYEEDREMLAKHLADICEGREMVHNLHYRWLDKEGMPVWINSRGIVVNDQQGNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCEEEEECCCCCH
EYLVGCLNETGNKRRADNVTGLLGGPEFLAYLRAQKEPITKGFFMHIGIDDFGAINSSRG
HHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCC
ADYGNYILKSVAGCMKECLSDKQRIYHLVADQYVIVDLEASSAEEAVALKEKITDKLHNF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
IVDENYEAIFSISIGVIDAATFCEGTEECRKKFEFALKQAKSMGKNGFYIFDQDDYEVFL
HCCCCCEEEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
QQGRIIATLRNAIVNHYDGFEVYYQPIVDCQSEQIIGAEALMRFSMITEEGREFVSPVEF
HCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHH
IPLLEETGLIIPAGRYILNEAAAMCCEMQKYIPDFRMNVNVSYVQILQGNVERDILDAIQ
HHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCEECCCHHHHEEHHCCCHHHHHHHHH
KYSLQPECLCVEMTESGFMDMTPSFCKFRKTLDKNGIPFVIDDFGTGYSNLHCIRDMNPS
HCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCC
YVKMDRDFTDKAMNSDRDYELYKNIITMVHSINVRICAEGIEEKEWLLKMKEMKVDYLQG
EEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCC
YYLGRPCGKKQFLQQYASGINIK
EECCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]