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The map label for this gene is ribE [H]

Identifier: 238921880

GI number: 238921880

Start: 86512

End: 87156

Strand: Reverse

Name: ribE [H]

Synonym: EUBELI_20113

Alternate gene names: 238921880

Gene position: 87156-86512 (Counterclockwise)

Preceding gene: 238921881

Following gene: 238921879

Centisome position: 13.91

GC content: 40.31

Gene sequence:

>645_bases
ATGTTTACAGGAATTATTGAAGAAATCGGACATGTAAATAATGTAAAAAAAGGAACGGCATCAGCAATTCTTACAATACA
GGCAGAAAAAGTCCTTAAGGGAACACATATAGGAGACAGCATTGCTGTCAATGGTGTGTGCCTTACAGTGACAGGGATAT
ATGATAATACATTTACTGCGGATGTAATGCATGAGACGCTGAACCGCTCATCACTTGGCAAGCTGGTGAGTGGCAGTGCT
GTTAATCTTGAAAGGGCAATGGCAGCAGATGGAAGGTTCGGAGGGCACATAGTTTCAGGACATATTGATGGAACAGGAAA
AGTTGCAGCGATAACCAGGGATGATAACGCGATATGGTATCAGATTAAGACAGACATCGGAATATTAAAATATATTGTTG
AAAAAGGTTCAGTTGCCATAGATGGAATAAGTCTTACGGTTGCCAAGACGGACAGCCAGAGCTTTTCAGTATCAATAATA
CCACATACGGCAGGTGCGACAACGCTGTCACTTAGGAAAGCTGGTGATGTAGTTAATCTTGAAAATGATATTGTCGGTAA
GTACATAGAGAAATTCATCACATTTGAAAAGGAAAAGCCGAAAAGCGGGATAACGAAAGAGTTCCTGCTAAAGAATGGAT
TTTAA

Upstream 100 bases:

>100_bases
TTGAAGGGCAGGGTATTGCAAATGTAGATGAAGCATATCGGTTGAGAAACAAAACCGTTCGTCTTCTTGGTGACGATATT
CTGATTGAAGGAGAGTTGTA

Downstream 100 bases:

>100_bases
AATATCAAAGGGAAAGGAAGGTAAAAGAAAATGTTTGAGTATAACACAGTAGAAGAGGCAGTTAAGGATTTACAGGATGG
AAAGCTGATACTTGTCTCAG

Product: riboflavin synthase alpha chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MFTGIIEEIGHVNNVKKGTASAILTIQAEKVLKGTHIGDSIAVNGVCLTVTGIYDNTFTADVMHETLNRSSLGKLVSGSA
VNLERAMAADGRFGGHIVSGHIDGTGKVAAITRDDNAIWYQIKTDIGILKYIVEKGSVAIDGISLTVAKTDSQSFSVSII
PHTAGATTLSLRKAGDVVNLENDIVGKYIEKFITFEKEKPKSGITKEFLLKNGF

Sequences:

>Translated_214_residues
MFTGIIEEIGHVNNVKKGTASAILTIQAEKVLKGTHIGDSIAVNGVCLTVTGIYDNTFTADVMHETLNRSSLGKLVSGSA
VNLERAMAADGRFGGHIVSGHIDGTGKVAAITRDDNAIWYQIKTDIGILKYIVEKGSVAIDGISLTVAKTDSQSFSVSII
PHTAGATTLSLRKAGDVVNLENDIVGKYIEKFITFEKEKPKSGITKEFLLKNGF
>Mature_214_residues
MFTGIIEEIGHVNNVKKGTASAILTIQAEKVLKGTHIGDSIAVNGVCLTVTGIYDNTFTADVMHETLNRSSLGKLVSGSA
VNLERAMAADGRFGGHIVSGHIDGTGKVAAITRDDNAIWYQIKTDIGILKYIVEKGSVAIDGISLTVAKTDSQSFSVSII
PHTAGATTLSLRKAGDVVNLENDIVGKYIEKFITFEKEKPKSGITKEFLLKNGF

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=186, Percent_Identity=40.3225806451613, Blast_Score=124, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6319733, Length=226, Percent_Identity=40.7079646017699, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22795; Mature: 22795

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIEEIGHVNNVKKGTASAILTIQAEKVLKGTHIGDSIAVNGVCLTVTGIYDNTFTA
CCCCHHHHHHCCCCCCCCCCEEEEEEEEHHHHCCCCCCCCEEECCEEEEEEEECCCCCHH
DVMHETLNRSSLGKLVSGSAVNLERAMAADGRFGGHIVSGHIDGTGKVAAITRDDNAIWY
HHHHHHHCHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCEEEE
QIKTDIGILKYIVEKGSVAIDGISLTVAKTDSQSFSVSIIPHTAGATTLSLRKAGDVVNL
EEECCHHHHHHHHHCCCEEEECEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCEEEC
ENDIVGKYIEKFITFEKEKPKSGITKEFLLKNGF
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MFTGIIEEIGHVNNVKKGTASAILTIQAEKVLKGTHIGDSIAVNGVCLTVTGIYDNTFTA
CCCCHHHHHHCCCCCCCCCCEEEEEEEEHHHHCCCCCCCCEEECCEEEEEEEECCCCCHH
DVMHETLNRSSLGKLVSGSAVNLERAMAADGRFGGHIVSGHIDGTGKVAAITRDDNAIWY
HHHHHHHCHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCEEEE
QIKTDIGILKYIVEKGSVAIDGISLTVAKTDSQSFSVSIIPHTAGATTLSLRKAGDVVNL
EEECCHHHHHHHHHCCCEEEECEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCEEEC
ENDIVGKYIEKFITFEKEKPKSGITKEFLLKNGF
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]