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The map label for this gene is ribH [H]

Identifier: 238921878

GI number: 238921878

Start: 84779

End: 85249

Strand: Reverse

Name: ribH [H]

Synonym: EUBELI_20111

Alternate gene names: 238921878

Gene position: 85249-84779 (Counterclockwise)

Preceding gene: 238921879

Following gene: 238921877

Centisome position: 13.6

GC content: 40.34

Gene sequence:

>471_bases
ATGATGAGAGTTTTAGAAGGTAAGTTAGTTGACAGTGGAATTAAGGTAGGTATTGTAGCAGCAAGATTTAATGAATTTAT
TGTGTCTAAGCTTGTTGCAGGAGCTAAGGACGGACTTGTAAGACATGATGTTTCAGAGGAAAATATTGACCTTGCATGGG
TACCGGGTGCATTTGAGATACCATTGATAGCTTCAAAGATGGCAAAAAGCGGAAAGTATGACGCAGTTATATGTCTTGGT
GCAGTTATAAGAGGTGCTACAAGCCACTACGATTATGTGTGCAGCGAGGTTTCCAAAGGCATTGCAAATGTTTCTTTAGC
AAGTGATATTCCTGTTATGTTTGGAGTGCTTACTACAGATACAATCGAGCAGGCAATTGAGCGTGCCGGAACAAAGGCAG
GCAATAAGGGATTTGAGTGCGCTGAAGGTGCTATTGAGATGGTTAATCTTATTAAAGAGATTGAAGGATAA

Upstream 100 bases:

>100_bases
CGACCAGCTTTGACAGGTTCTATCTTAAGACAAAGCAGACAAAGATGGGACACATTTTAAATGTGGTGTAAAAAAATGAA
ATATTTATAAGGAGGAATTG

Downstream 100 bases:

>100_bases
TATATAAAATTTTTAGTAATTGTAAAAGGTCAGATTCGTCAGTAACCATTGGGCTTGGCGGGTCTGACCTTTTGTATTAT
AAAATATGATATAAAATGGA

Product: riboflavin synthase beta chain

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MMRVLEGKLVDSGIKVGIVAARFNEFIVSKLVAGAKDGLVRHDVSEENIDLAWVPGAFEIPLIASKMAKSGKYDAVICLG
AVIRGATSHYDYVCSEVSKGIANVSLASDIPVMFGVLTTDTIEQAIERAGTKAGNKGFECAEGAIEMVNLIKEIEG

Sequences:

>Translated_156_residues
MMRVLEGKLVDSGIKVGIVAARFNEFIVSKLVAGAKDGLVRHDVSEENIDLAWVPGAFEIPLIASKMAKSGKYDAVICLG
AVIRGATSHYDYVCSEVSKGIANVSLASDIPVMFGVLTTDTIEQAIERAGTKAGNKGFECAEGAIEMVNLIKEIEG
>Mature_156_residues
MMRVLEGKLVDSGIKVGIVAARFNEFIVSKLVAGAKDGLVRHDVSEENIDLAWVPGAFEIPLIASKMAKSGKYDAVICLG
AVIRGATSHYDYVCSEVSKGIANVSLASDIPVMFGVLTTDTIEQAIERAGTKAGNKGFECAEGAIEMVNLIKEIEG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=155, Percent_Identity=55.4838709677419, Blast_Score=173, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324429, Length=145, Percent_Identity=37.9310344827586, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16532; Mature: 16532

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRVLEGKLVDSGIKVGIVAARFNEFIVSKLVAGAKDGLVRHDVSEENIDLAWVPGAFEI
CCCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCEEECCCCCCC
PLIASKMAKSGKYDAVICLGAVIRGATSHYDYVCSEVSKGIANVSLASDIPVMFGVLTTD
HHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHH
TIEQAIERAGTKAGNKGFECAEGAIEMVNLIKEIEG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMRVLEGKLVDSGIKVGIVAARFNEFIVSKLVAGAKDGLVRHDVSEENIDLAWVPGAFEI
CCCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCEEECCCCCCC
PLIASKMAKSGKYDAVICLGAVIRGATSHYDYVCSEVSKGIANVSLASDIPVMFGVLTTD
HHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHH
TIEQAIERAGTKAGNKGFECAEGAIEMVNLIKEIEG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA