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The map label for this gene is glmS [H]

Identifier: 238921746

GI number: 238921746

Start: 3793162

End: 3794991

Strand: Direct

Name: glmS [H]

Synonym: NT01EI_3915

Alternate gene names: 238921746

Gene position: 3793162-3794991 (Clockwise)

Preceding gene: 238921745

Following gene: 238921748

Centisome position: 99.5

GC content: 57.87

Gene sequence:

>1830_bases
ATGTGTGGAATTGTTGGCGCGGTAGCGCAGCGAGATGTGGCAGAGATCCTGCTGGAAGGGTTACGTCGTCTGGAGTACCG
AGGCTATGACTCTGCAGGTCTGGCAGTCGTGGACGCGCAGGGACATATGCAGCGTCTACGTCGTGTAGGCAAGGTCAATG
CTTTAAACGACGCGGTTGCCCTGTCGCCAATGGTCGGCGGCACCGGTATTGCCCACACCCGCTGGGCAACCCATGGTGAA
CCGAGTGAACAGAATGCGCATCCCCATGTATCCGGCCACATCAGCGTGGTGCACAACGGTATTATCGAAAACCACGAGAC
GCTGCGCGCACAGCTGATTGAGCGCGGCTACCGTTTTACCTCCGAGACGGATACGGAGGTGATTGCGCACCTGGTAAACT
GGGAACAACGCCAGGGAGGATCCCTGCTGGAGGTCGTTAAGCGGGTCATCCCGCAGCTGCGCGGCGCATATGGTACGGTA
GTGATGGACAGCCAGCACCCAGGAGTGCTGGTCTGTGCTCGCTCAGGTAGCCCGCTGGTGATTGGCCGAGGAATGGGGGA
GAACTTTCTGGCCTCCGATCAGCTGGCGCTGCTGCCGGTCACCCGCCGCTTTATCTTCCTGGAAGAGGGGGATATTGCCG
AGCTAACCCGCCACAGCGTGACCATCTTTGACGCCACCGGTGCACCGGCGGCACGTGCCGAAGTCGAATCCAACGTGCAG
TATGATGCCGGTGATAAGGGTGACTATCGCCACTACATGCAGAAAGAGATTTACGAACAGCCGCAGGCGATCAAAAACAC
CCTTGAGGGGCGCTTTAGCCACGGTCAAATCGATCTGCAGGAGCTGGGCGAGGCCGGAGAGCGCCTGCTGTCGCAGGTTG
AGCATATCCAAATTATCGCCTGCGGAACGTCATACCACTCCGGTATGGTTGCCCGCTATTGGTTTGAGGCGCTGGCCGGC
GTTCCCTGCGATGTAGAGATCGCCTCTGAATTCCGCTACCGTAAGTCAGCCGTGCGTAAAAACAGCTTGATAATAACGCT
GTCTCAGTCAGGTGAAACGGCCGATACGCTGGCGGCGTTGCGCCTGTCCAAAGAGATTGGCTACCTGGGGTCGCTGGCAA
TTTGTAACGTAGCCAGCTCCTCGCTGGTGCGCGAGTCCGACTTAGCGCTGATGACCCGCGCCGGCACTGAAATCGGCGTT
GCGTCAACCAAGGCCTTCACTACTCAGCTGACGGTATTGCTGATGCTGGTGGCGCGTATTGGTCGTCTACACGCGATGTC
AGTGGAGGCGGAGCAGGAGATTGTCCATGCCCTGCAGGCGTTACCGAACCGTATTGAGCAGATGCTTTCGCTGGATCGCA
GCATTGAAGCGCTGGCCGAAGATTTTCTGGATAAGCACCACGCGCTGTTTTTAGGGCGCGGCGATCAGTATCCGATCGCG
ATGGAAGGGGCGCTGAAGCTGAAGGAGATCTCCTATATCCATGCCGAGGCCTACGCCGCCGGTGAGCTGAAGCATGGTCC
ACTGGCGCTGATCGACTCCGATATGCCAGTGGTGGTGGTGGCGCCGAATAATGAGCTGCTGGAGAAGTTAAAATCCAATA
TTGAAGAGGTGCGTGCCCGCGGCGGTCTGCTGTACGTTTTCGCTGCCCAGAGCGCCGGGTTTAGCAAAAGTGAAGGGATG
CGTATTATCGCTCTGCCACACGTAGAAGAGGTGATTGCACCGATTTTCTATACGGTGCCGCTGCAGCTGCTCTCCTATCA
TGTCGCCCTGATCAAGGGGACCGACGTCGATCAGCCGCGTAACCTGGCTAAGTCGGTTACCGTAGAATAA

Upstream 100 bases:

>100_bases
TACAAGGCTCGGGGCAGCGGCGCACAGCGCCGTTTATCAATCAGATCGATACGGGCATCGACAAACCGCTGTGGCGGTTT
GGCTATAGGAAGAAAACCTT

Downstream 100 bases:

>100_bases
AGCGCGATCGTGAGATATCAGGGGATGCCTCGGCATCCCCTTTTTATTGAGTAACGATTAGCGAGAAAGGGTGGACGATA
AATAGCGTAGCCACCATAGC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAQGHMQRLRRVGKVNALNDAVALSPMVGGTGIAHTRWATHGE
PSEQNAHPHVSGHISVVHNGIIENHETLRAQLIERGYRFTSETDTEVIAHLVNWEQRQGGSLLEVVKRVIPQLRGAYGTV
VMDSQHPGVLVCARSGSPLVIGRGMGENFLASDQLALLPVTRRFIFLEEGDIAELTRHSVTIFDATGAPAARAEVESNVQ
YDAGDKGDYRHYMQKEIYEQPQAIKNTLEGRFSHGQIDLQELGEAGERLLSQVEHIQIIACGTSYHSGMVARYWFEALAG
VPCDVEIASEFRYRKSAVRKNSLIITLSQSGETADTLAALRLSKEIGYLGSLAICNVASSSLVRESDLALMTRAGTEIGV
ASTKAFTTQLTVLLMLVARIGRLHAMSVEAEQEIVHALQALPNRIEQMLSLDRSIEALAEDFLDKHHALFLGRGDQYPIA
MEGALKLKEISYIHAEAYAAGELKHGPLALIDSDMPVVVVAPNNELLEKLKSNIEEVRARGGLLYVFAAQSAGFSKSEGM
RIIALPHVEEVIAPIFYTVPLQLLSYHVALIKGTDVDQPRNLAKSVTVE

Sequences:

>Translated_609_residues
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAQGHMQRLRRVGKVNALNDAVALSPMVGGTGIAHTRWATHGE
PSEQNAHPHVSGHISVVHNGIIENHETLRAQLIERGYRFTSETDTEVIAHLVNWEQRQGGSLLEVVKRVIPQLRGAYGTV
VMDSQHPGVLVCARSGSPLVIGRGMGENFLASDQLALLPVTRRFIFLEEGDIAELTRHSVTIFDATGAPAARAEVESNVQ
YDAGDKGDYRHYMQKEIYEQPQAIKNTLEGRFSHGQIDLQELGEAGERLLSQVEHIQIIACGTSYHSGMVARYWFEALAG
VPCDVEIASEFRYRKSAVRKNSLIITLSQSGETADTLAALRLSKEIGYLGSLAICNVASSSLVRESDLALMTRAGTEIGV
ASTKAFTTQLTVLLMLVARIGRLHAMSVEAEQEIVHALQALPNRIEQMLSLDRSIEALAEDFLDKHHALFLGRGDQYPIA
MEGALKLKEISYIHAEAYAAGELKHGPLALIDSDMPVVVVAPNNELLEKLKSNIEEVRARGGLLYVFAAQSAGFSKSEGM
RIIALPHVEEVIAPIFYTVPLQLLSYHVALIKGTDVDQPRNLAKSVTVE
>Mature_609_residues
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAQGHMQRLRRVGKVNALNDAVALSPMVGGTGIAHTRWATHGE
PSEQNAHPHVSGHISVVHNGIIENHETLRAQLIERGYRFTSETDTEVIAHLVNWEQRQGGSLLEVVKRVIPQLRGAYGTV
VMDSQHPGVLVCARSGSPLVIGRGMGENFLASDQLALLPVTRRFIFLEEGDIAELTRHSVTIFDATGAPAARAEVESNVQ
YDAGDKGDYRHYMQKEIYEQPQAIKNTLEGRFSHGQIDLQELGEAGERLLSQVEHIQIIACGTSYHSGMVARYWFEALAG
VPCDVEIASEFRYRKSAVRKNSLIITLSQSGETADTLAALRLSKEIGYLGSLAICNVASSSLVRESDLALMTRAGTEIGV
ASTKAFTTQLTVLLMLVARIGRLHAMSVEAEQEIVHALQALPNRIEQMLSLDRSIEALAEDFLDKHHALFLGRGDQYPIA
MEGALKLKEISYIHAEAYAAGELKHGPLALIDSDMPVVVVAPNNELLEKLKSNIEEVRARGGLLYVFAAQSAGFSKSEGM
RIIALPHVEEVIAPIFYTVPLQLLSYHVALIKGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=686, Percent_Identity=38.0466472303207, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI205277386, Length=683, Percent_Identity=38.0673499267936, Blast_Score=418, Evalue=1e-117,
Organism=Homo sapiens, GI29570798, Length=270, Percent_Identity=27.4074074074074, Blast_Score=83, Evalue=9e-16,
Organism=Escherichia coli, GI1790167, Length=609, Percent_Identity=82.5944170771757, Blast_Score=1036, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=226, Percent_Identity=30.0884955752212, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539970, Length=430, Percent_Identity=39.5348837209302, Blast_Score=290, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17532899, Length=431, Percent_Identity=38.2830626450116, Blast_Score=284, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17532897, Length=431, Percent_Identity=38.2830626450116, Blast_Score=283, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6322745, Length=447, Percent_Identity=38.7024608501119, Blast_Score=288, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6323731, Length=439, Percent_Identity=32.8018223234624, Blast_Score=207, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6323730, Length=221, Percent_Identity=36.6515837104072, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21357745, Length=690, Percent_Identity=37.2463768115942, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI28573187, Length=296, Percent_Identity=25.3378378378378, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24659598, Length=260, Percent_Identity=24.6153846153846, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24659604, Length=236, Percent_Identity=24.1525423728814, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66535; Mature: 66535

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAQGHMQRLRRVGKVNALNDAVA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCHHE
LSPMVGGTGIAHTRWATHGEPSEQNAHPHVSGHISVVHNGIIENHETLRAQLIERGYRFT
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHCCHHHHHHHHHHHCCCCC
SETDTEVIAHLVNWEQRQGGSLLEVVKRVIPQLRGAYGTVVMDSQHPGVLVCARSGSPLV
CCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCEE
IGRGMGENFLASDQLALLPVTRRFIFLEEGDIAELTRHSVTIFDATGAPAARAEVESNVQ
EECCCCCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHCEEEEEECCCCCHHHHHHHCCCC
YDAGDKGDYRHYMQKEIYEQPQAIKNTLEGRFSHGQIDLQELGEAGERLLSQVEHIQIIA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHCEEEEEE
CGTSYHSGMVARYWFEALAGVPCDVEIASEFRYRKSAVRKNSLIITLSQSGETADTLAAL
ECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
RLSKEIGYLGSLAICNVASSSLVRESDLALMTRAGTEIGVASTKAFTTQLTVLLMLVARI
HHHHHHCCHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GRLHAMSVEAEQEIVHALQALPNRIEQMLSLDRSIEALAEDFLDKHHALFLGRGDQYPIA
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEE
MEGALKLKEISYIHAEAYAAGELKHGPLALIDSDMPVVVVAPNNELLEKLKSNIEEVRAR
ECCCEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHC
GGLLYVFAAQSAGFSKSEGMRIIALPHVEEVIAPIFYTVPLQLLSYHVALIKGTDVDQPR
CCEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCH
NLAKSVTVE
HHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAQGHMQRLRRVGKVNALNDAVA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCHHE
LSPMVGGTGIAHTRWATHGEPSEQNAHPHVSGHISVVHNGIIENHETLRAQLIERGYRFT
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHCCHHHHHHHHHHHCCCCC
SETDTEVIAHLVNWEQRQGGSLLEVVKRVIPQLRGAYGTVVMDSQHPGVLVCARSGSPLV
CCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCEE
IGRGMGENFLASDQLALLPVTRRFIFLEEGDIAELTRHSVTIFDATGAPAARAEVESNVQ
EECCCCCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHCEEEEEECCCCCHHHHHHHCCCC
YDAGDKGDYRHYMQKEIYEQPQAIKNTLEGRFSHGQIDLQELGEAGERLLSQVEHIQIIA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHCEEEEEE
CGTSYHSGMVARYWFEALAGVPCDVEIASEFRYRKSAVRKNSLIITLSQSGETADTLAAL
ECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
RLSKEIGYLGSLAICNVASSSLVRESDLALMTRAGTEIGVASTKAFTTQLTVLLMLVARI
HHHHHHCCHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
GRLHAMSVEAEQEIVHALQALPNRIEQMLSLDRSIEALAEDFLDKHHALFLGRGDQYPIA
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEE
MEGALKLKEISYIHAEAYAAGELKHGPLALIDSDMPVVVVAPNNELLEKLKSNIEEVRAR
ECCCEEHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHC
GGLLYVFAAQSAGFSKSEGMRIIALPHVEEVIAPIFYTVPLQLLSYHVALIKGTDVDQPR
CCEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCH
NLAKSVTVE
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]