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The map label for this gene is atpA [H]

Identifier: 238921741

GI number: 238921741

Start: 3786982

End: 3788523

Strand: Direct

Name: atpA [H]

Synonym: NT01EI_3910

Alternate gene names: 238921741

Gene position: 3786982-3788523 (Clockwise)

Preceding gene: 238921740

Following gene: 238921742

Centisome position: 99.34

GC content: 58.04

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACCGAAATCAGCGAACTGATCAAGCAGCGCATTGCTCAGTTCGACGTGGTGAGCGAAGCTCACAA
CGAAGGTACAATCGTCTCAGTGAGCGACGGGATTATCCGCGTTCACGGTCTGGCGGACGTCATGCAGGGCGAAATGATCG
CGCTGCCGGGTAACCGCTACGCTATCGCACTGAACCTGGAGCGCGACTCTGTGGGTGCGGTAGTTATGGGGCCCTACGCT
GACCTTGCCGAAGGCATGAAGGTCAAGTGTACCGGCCGTATTCTGGAAGTTCCGGTAGGCCGTGGTTTGCTGGGCCGCGT
GGTGAACACCCTGGGTGAGCCGATCGACGGTAAAGGTCCGGTCGAGCACGACGGGTTCTCCGCTGTTGAAGCCATCGCCC
CGGGCGTTATCGAACGTCAGTCTGTCGATCAGCCGGTACAGACGGGCTATAAGTCCGTGGATGCCATGATCCCTATCGGT
CGCGGTCAGCGTGAGCTTGTCATCGGCGACCGTCAGACCGGTAAAACCGCGCTGGCCGTCGATGCCATTATCAACCAGCG
TGACTCCGGCATTAAGTGTATCTATGTCGCCGTAGGTCAGAAGGCTTCTACCATTGCTAACGTGGTGCGTAAGCTGGAAG
AGCACGGCGCGCTGGCTAACACCATTGTCGTCGTGGCCTCGGCCTCAGAATCCGCCGCCCTGCAGTACCTGGCGCCGTAC
GCCGGCTGTGCGATGGGGGAATATTTCCGAGATCGCGGTGAAGACGCGCTGATCATCTATGATGACTTGTCCAAGCAAGC
GGTCGCTTATCGCCAAATATCCCTGCTGCTCCGTCGCCCGCCAGGTCGTGAAGCATTTCCGGGTGACGTATTTTACCTCC
ACTCCCGTCTGCTGGAGCGTGCAGCGCGCGTTAACGCTGAGTACGTCGAGACCTTCACCAAGGGTGAGGTCAAGGGTAAG
ACGGGTTCACTGACGGCGCTGCCGATCATTGAAACCCAGGCTGGTGACGTTTCCGCGTTCGTTCCGACCAACGTAATCTC
GATTACCGATGGTCAGATCTTCCTGGAATCTAACCTGTTTAACGCCGGTATCCGCCCTGCGGTAAACCCGGGGATCTCCG
TATCCCGTGTGGGTGGCGCGGCGCAGACCAAGATCATGAAGAAACTGTCCGGCGGTATCCGTACCGCTCTGGCGCAGTAC
CGTGAACTGGCGGCGTTTTCTCAGTTTGCCTCTGATCTGGACGATGCGACCCGGAAACAGCTGAGCCACGGCCAGAAGGT
GACTGAGCTGCTCAAGCAGAAACAGTATGCGCCGATGTCTGTCGCTACGCAGTCGCTGGTGCTGTTCGCCGCTGAGCGTG
GCTACCTGGAAGATGTCGAGCTGGCGAAGGTTGGCGGCTTCGAAGCGGCGCTGATGGCTTACGTTGATCGCGAGCACGCT
GACCTGATGCAACAAATCAACCAGACCGGTGCTTATAACGACGAGATCGAAGGCAAGCTGAAAGGCATTCTCGATACCTT
CAAAGCAACCCAGTCCTGGTAA

Upstream 100 bases:

>100_bases
CGGCGTGGTTATCCGCGCGGGTGACCTGGTGATCGATGGCAGCATTCGTGGCCGTTTGGATCGCCTGACAGACGTCTTGC
AGTCTTAAGGGGACTGGAGC

Downstream 100 bases:

>100_bases
TAGCCTTACGGCCTGCCGGCAGTAATACGGTGGGCCGTAAAAGGTTTTGAGGAGAAGCAGAGATGGCCGGCGCGAAAGAG
ATACGTAGCAAGATCGCCAG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISELIKQRIAQFDVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGPVEHDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIG
RGQRELVIGDRQTGKTALAVDAIINQRDSGIKCIYVAVGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVETFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVATQSLVLFAAERGYLEDVELAKVGGFEAALMAYVDREHA
DLMQQINQTGAYNDEIEGKLKGILDTFKATQSW

Sequences:

>Translated_513_residues
MQLNSTEISELIKQRIAQFDVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGPVEHDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIG
RGQRELVIGDRQTGKTALAVDAIINQRDSGIKCIYVAVGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVETFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVATQSLVLFAAERGYLEDVELAKVGGFEAALMAYVDREHA
DLMQQINQTGAYNDEIEGKLKGILDTFKATQSW
>Mature_513_residues
MQLNSTEISELIKQRIAQFDVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGPVEHDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIG
RGQRELVIGDRQTGKTALAVDAIINQRDSGIKCIYVAVGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVETFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVATQSLVLFAAERGYLEDVELAKVGGFEAALMAYVDREHA
DLMQQINQTGAYNDEIEGKLKGILDTFKATQSW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=55.3606237816764, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=55.3606237816764, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI19913426, Length=312, Percent_Identity=28.2051282051282, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI19913428, Length=314, Percent_Identity=28.343949044586, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI32189394, Length=431, Percent_Identity=24.8259860788863, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI19913424, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=94.3469785575049, Blast_Score=1001, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=340, Percent_Identity=26.7647058823529, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788251, Length=345, Percent_Identity=24.6376811594203, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=54.1747572815534, Blast_Score=550, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=54.1747572815534, Blast_Score=549, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=50.4854368932039, Blast_Score=503, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=25.8152173913043, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=311, Percent_Identity=26.0450160771704, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=431, Percent_Identity=24.8259860788863, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=65.9574468085106, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=25.9842519685039, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=52.4366471734893, Blast_Score=550, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6322581, Length=366, Percent_Identity=26.775956284153, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319603, Length=370, Percent_Identity=25.4054054054054, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=54.0856031128405, Blast_Score=546, Evalue=1e-155,
Organism=Drosophila melanogaster, GI281361666, Length=313, Percent_Identity=27.1565495207668, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24646341, Length=313, Percent_Identity=27.1565495207668, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136796, Length=313, Percent_Identity=27.1565495207668, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24638766, Length=432, Percent_Identity=25.2314814814815, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=25.5451713395639, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24583992, Length=336, Percent_Identity=24.702380952381, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24583988, Length=259, Percent_Identity=26.6409266409266, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24583986, Length=259, Percent_Identity=26.6409266409266, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24583984, Length=259, Percent_Identity=26.6409266409266, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55226; Mature: 55226

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISELIKQRIAQFDVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECHHHHHCCCEEEECCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
VEHDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTALAV
CCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCCCHHHHH
DAIINQRDSGIKCIYVAVGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEYVETFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCC
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHGQKVTELLKQKQYAPMSVATQSLVLFAAERGYLEDVELAKVGGFEAALMAYVDREHA
HHCCHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHH
DLMQQINQTGAYNDEIEGKLKGILDTFKATQSW
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLNSTEISELIKQRIAQFDVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRY
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEECHHHHHCCCEEEECCCEE
AIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCCHHHHCCCEEEECCEEEECCCCCCHHHHHHHHHCCCCCCCCC
VEHDGFSAVEAIAPGVIERQSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTALAV
CCCCCHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCCCHHHHH
DAIINQRDSGIKCIYVAVGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
HHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEYVETFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCC
NAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQ
CCCCCCCCCCCCEEHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHGQKVTELLKQKQYAPMSVATQSLVLFAAERGYLEDVELAKVGGFEAALMAYVDREHA
HHCCHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHH
DLMQQINQTGAYNDEIEGKLKGILDTFKATQSW
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA