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The map label for this gene is uhpC [H]

Identifier: 238921614

GI number: 238921614

Start: 3652737

End: 3654077

Strand: Reverse

Name: uhpC [H]

Synonym: NT01EI_3769

Alternate gene names: 238921614

Gene position: 3654077-3652737 (Counterclockwise)

Preceding gene: 238921615

Following gene: 238921612

Centisome position: 95.85

GC content: 56.97

Gene sequence:

>1341_bases
ATGTGGTCTTTTCTGAAAAGCCGCACCGACGCACCCGAGATTCAGGATAGTGCCAAGGTTGATGCTGCCTATAAATATTG
GCGCATCCAGCTGATGTGGGTCATGTATGTTGGCTACGCCGCTTTTTACTTTACCCGCAAAAGCTTCAACTTCATCATGC
CGGAAATGATAAGTGATCTGGGGCTGAGCATGTCCGATATCGGCATCATGGGCACGCTGTTCTATATCACCTATGGCTGT
TCCAAGTTTATCTCCGGGATGATCAGCGATCGTTCCAACCCACGCTATTTTATGGGGTTGGGGCTGATCATGACCGGTAT
TATCAATATCGTCTTCGGGATGAGTTCGTCGCTGCTGGTGCTGGGGGCGCTGTGGATGGTGAACGCCTTCTTCCAGGGCT
GGGGCTGGCCGCCGTGCTCGAAGATCCTGACCAGCTGGTATTCACGCGCCGAACGCGGCAGCTGGTGGGCCATCTGGAAT
ACTTCCCATAATGTCGGCGGCGCGCTGATCCCGCTGCTGGTCGGTTTTATCTCCCTGCACTTCAGCTGGCGCTATGGGAT
GATCATCCCCGGGATTATCGGGATTGTACTGGGGCTGCTGATGTGCTGGCGCCTGCGCGACAAGCCGGTCACGATGGGGT
TGCCGAGCGTCGGAAAATGGCGTAATGACGCCCTTGAGCTGGTGCAGGAGTCCGAAGGCAAGGGGCTATCCAATAAAGAG
ATCATCAAGCGCTATGTGCTGACGAATAAGTACATCTGGCTGCTGGCAGTCTCTTATGTTCTGGTATATATCGTGCGTAC
CGCGATCAATGACTGGGGAAACCTGTACCTGACCCAGACCAAGGGCTACTCGCTGATGACTGCCAACTCGGCGCTGTCGC
TATTTGAGGTGGGGGGCTTTATCGGGTCTCTGGTCGCCGGCTGGGGCTCAGACAGGTTGTTCCGCGGCAACCGTGGTCCC
ATGAACCTGATCTTCGCTATCGGGATCTTCCTCTCTGTGGCCGCGCTGTGGCTGATGCCGGGCGGCAGCTATGCGCTGCA
GGCCGCCTGTTTCTTCTCTATCGGTTTCTTCATCTTTGGCCCGCAGATGCTGATCGGGATGGCCGCTGCCGAGTGTTCCC
ATAAGGATGCGGCTGGCGCGGCGACCGGTTTTGTCGGCCTGTTCGCCTATCTGGGAGCAGCGCTTTCCGGCTATCCGATC
GCCCGGGTGATGGAAGTGTGGCACTGGAACGGCTTTTTCGTCGTGATTTCCGTAGCGGCCTGTCTGTCCGCGCTGTTTCT
GCTGCCGTTCCTGCGTGCACAGAAAGACCGGGAGCAAAACGCCACCGGCGGTGCAGGTTAA

Upstream 100 bases:

>100_bases
TTTCTTAGTGCCAGCGGGAGATTTGTATTAGTTATCCCGTGCGTGCGCGACGCACCATAGCGTCTACAACGATGAGTTTT
CACGCACGAGGTATTTCCCC

Downstream 100 bases:

>100_bases
CGCTTGAGTTCGCTGTGTGTGGTTCGATAAAAAAAGCATGGCTTCGGCCATGCTTTTTGCTATCTGAAGGCGGTGAACTG
TGGCTAAAATGCAGACAACG

Product: regulatory protein UhpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MWSFLKSRTDAPEIQDSAKVDAAYKYWRIQLMWVMYVGYAAFYFTRKSFNFIMPEMISDLGLSMSDIGIMGTLFYITYGC
SKFISGMISDRSNPRYFMGLGLIMTGIINIVFGMSSSLLVLGALWMVNAFFQGWGWPPCSKILTSWYSRAERGSWWAIWN
TSHNVGGALIPLLVGFISLHFSWRYGMIIPGIIGIVLGLLMCWRLRDKPVTMGLPSVGKWRNDALELVQESEGKGLSNKE
IIKRYVLTNKYIWLLAVSYVLVYIVRTAINDWGNLYLTQTKGYSLMTANSALSLFEVGGFIGSLVAGWGSDRLFRGNRGP
MNLIFAIGIFLSVAALWLMPGGSYALQAACFFSIGFFIFGPQMLIGMAAAECSHKDAAGAATGFVGLFAYLGAALSGYPI
ARVMEVWHWNGFFVVISVAACLSALFLLPFLRAQKDREQNATGGAG

Sequences:

>Translated_446_residues
MWSFLKSRTDAPEIQDSAKVDAAYKYWRIQLMWVMYVGYAAFYFTRKSFNFIMPEMISDLGLSMSDIGIMGTLFYITYGC
SKFISGMISDRSNPRYFMGLGLIMTGIINIVFGMSSSLLVLGALWMVNAFFQGWGWPPCSKILTSWYSRAERGSWWAIWN
TSHNVGGALIPLLVGFISLHFSWRYGMIIPGIIGIVLGLLMCWRLRDKPVTMGLPSVGKWRNDALELVQESEGKGLSNKE
IIKRYVLTNKYIWLLAVSYVLVYIVRTAINDWGNLYLTQTKGYSLMTANSALSLFEVGGFIGSLVAGWGSDRLFRGNRGP
MNLIFAIGIFLSVAALWLMPGGSYALQAACFFSIGFFIFGPQMLIGMAAAECSHKDAAGAATGFVGLFAYLGAALSGYPI
ARVMEVWHWNGFFVVISVAACLSALFLLPFLRAQKDREQNATGGAG
>Mature_446_residues
MWSFLKSRTDAPEIQDSAKVDAAYKYWRIQLMWVMYVGYAAFYFTRKSFNFIMPEMISDLGLSMSDIGIMGTLFYITYGC
SKFISGMISDRSNPRYFMGLGLIMTGIINIVFGMSSSLLVLGALWMVNAFFQGWGWPPCSKILTSWYSRAERGSWWAIWN
TSHNVGGALIPLLVGFISLHFSWRYGMIIPGIIGIVLGLLMCWRLRDKPVTMGLPSVGKWRNDALELVQESEGKGLSNKE
IIKRYVLTNKYIWLLAVSYVLVYIVRTAINDWGNLYLTQTKGYSLMTANSALSLFEVGGFIGSLVAGWGSDRLFRGNRGP
MNLIFAIGIFLSVAALWLMPGGSYALQAACFFSIGFFIFGPQMLIGMAAAECSHKDAAGAATGFVGLFAYLGAALSGYPI
ARVMEVWHWNGFFVVISVAACLSALFLLPFLRAQKDREQNATGGAG

Specific function: UhpC is required for uhpT expression, it may act jointly with the uhpB signaling protein [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=435, Percent_Identity=32.8735632183908, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI4503847, Length=435, Percent_Identity=32.8735632183908, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI256219483, Length=435, Percent_Identity=32.8735632183908, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI256219543, Length=448, Percent_Identity=31.4732142857143, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI256219564, Length=364, Percent_Identity=32.4175824175824, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI46361976, Length=399, Percent_Identity=22.3057644110276, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI14150047, Length=274, Percent_Identity=21.8978102189781, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI223717983, Length=409, Percent_Identity=25.9168704156479, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI38093649, Length=409, Percent_Identity=25.9168704156479, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI49619231, Length=455, Percent_Identity=23.7362637362637, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082310, Length=438, Percent_Identity=65.7534246575342, Blast_Score=626, Evalue=0.0,
Organism=Escherichia coli, GI1788573, Length=430, Percent_Identity=36.2790697674419, Blast_Score=292, Evalue=4e-80,
Organism=Escherichia coli, GI2367259, Length=433, Percent_Identity=32.3325635103926, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI2367379, Length=375, Percent_Identity=23.2, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082320, Length=306, Percent_Identity=22.8758169934641, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561094, Length=420, Percent_Identity=24.047619047619, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI133930953, Length=449, Percent_Identity=24.4988864142539, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17542316, Length=451, Percent_Identity=23.059866962306, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI133901856, Length=439, Percent_Identity=23.9179954441913, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI133901854, Length=439, Percent_Identity=23.9179954441913, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17539138, Length=319, Percent_Identity=23.1974921630094, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24656861, Length=481, Percent_Identity=23.2848232848233, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24656866, Length=481, Percent_Identity=23.2848232848233, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45550478, Length=481, Percent_Identity=23.2848232848233, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49451; Mature: 49451

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1569007; 11677609 [H]