Click here to switch to the map view.

The map label for this gene is dppA [H]

Identifier: 238921612

GI number: 238921612

Start: 3649480

End: 3651198

Strand: Reverse

Name: dppA [H]

Synonym: NT01EI_3765

Alternate gene names: 238921612

Gene position: 3651198-3649480 (Counterclockwise)

Preceding gene: 238921614

Following gene: 238921611

Centisome position: 95.77

GC content: 57.77

Gene sequence:

>1719_bases
TTGGCCGTACAGGCCGTTGCCGGACGGATCGTACAGAAAAAAACAGATATCTGCCGGGTCACACAACATCACAGTATGGA
GTTCAATGTTATGTCTTCCAATAATCACGCATCTACGGGTCGTGGCGCAGGCGCCGTCGCGCTGAAATGGGGTATCGGCC
TGGTTGCGTTGGCAGTTGCCGGCAGTCTGCAGGCGAAAACCCTGGTGTACTGTTCTGAGGGATCACCGGAGGGGTTTAAC
CCGCAGCTGTTTACCTCCGGTACCACCTATGACGCCAGCTCGGTACCCATCTATAACCGTCTGATCGAGTTTAAGAACGG
GAGCACGGAGCTCGTGCCCGGGCTGGCGGAGAGCTGGGAGGTGAGTCCCGATGGCAAGACCTATACCTTCCACCTGCGCA
AGGGGGTGAAGTGGCAGGGCAGTAAGCTGTTTACGCCGACCCGTGACTTCAACGCCAATGACGTGGTGTTCTCCTTCGAA
CGCCAGCGCGATCCGAGCCACCCGTACCACAAGGTCTCCGGCGGCAGCTATGAGTACTTCCAGGGGATGGGGCTGCCGGA
GCTGATATCCAGGGTCGAAAAGGTGGACGATAGCACGGTGCGTATCGAACTGAATCACCCGGAGTCGCCGTTCCTGGCGG
ATCTGGCGATGGACTTCGCGTCGATCCTGTCTGCCGAATATGCCGATGCCATGATGAAGGCAGGTACGCCGGAGAAGATC
GATCTGGAGCCGCTGGGCACCGGTCCATTCCAATTGATGCAGTACCAGAAGGATTCGAAGATCCTCTATAAAGCCAATAA
AGAGTATTGGGGTCCGCAGCCGAAGATCGACCGCCTGGTGTTCTCCATTACGCCGGATGCCTCGGTGCGCTATGCCAAGC
TGCAGAAGAATGAGTGTCAGGTGATGCCGTATCCGAATCCGGCGGATCTGGCGCGCATGAAGCAGGATAAGAATATTACC
CTGTTGGAGCAGCCAGGGCTTAACGTGGGCTACCTGTCGTTTAACGTCGATAAAAAGCCGCTGGATAACGTCAAGGTGCG
CCAGGCGCTGACCATGGCGGTCAACAAACCGGCCATCATTGAGGCTGTCTATCAGAAGGCCGGGCAGTCAGCGAAAAACC
TGATACCACCGACCATGTGGGGCTATAACGATGAGATTAAGGATTATCCGTACGATCCGGAGAAGGCCAAAGCGCTGCTG
AAGGAGGCCGGGTTAGCGGATGGGTTCAGCATTGACCTGTGGGCGATGCCGGTACAACGTCCTTATAACCCCAACGCGCG
CCGTATGGCCGAGATGATCCAGGCAGACTGGGACAAGATCGGCGTGAAAGCCAAGATTGTGACCTATGAGTGGGGAGAGT
ACCTCAAACGCGCCAAAGACGGCGAACATCAGGCGGTGATGATGGGCTGGACCGGCGATAACGGCGATCCGGACAACTTC
TTCGCTACGCTGTTCAGCTGCGATGCGGCCAAGCAGGGCTCCAACTACTCCCGCTGGTGCTATCAGCCGTTTGAGGCGGT
GATTCAGCCGGCGCGTGCCGAGGCGGACCAGGCCAAGCGCGCCGAGCTGTATCGCCAGGCCCAGGTGATTATGCATGGCC
AGGCACCGGCGCTGATCATCGCCCACTCCACCGTCTATGAGCCGGTGCGTAAAGAGGTGAAGGGCTACGTGGTGGATCCG
CTGGGCAAGCATCACTTCAATCAGGTCTCCCTGGAGTAA

Upstream 100 bases:

>100_bases
TTGGGGCGTATAAGGTGAAAACAGCGCTTCAGGATTGTGCATCTATTCGCTGATGGACTGCCCGATGAGTCGTTCCTCGC
CGGGATATTGTCTACTCACC

Downstream 100 bases:

>100_bases
TCCTGTCACCCCTTAAGGGTAAGGGGCTTCGTGAACCGTACCGCCGGCCGTGAGGTCAGGCGGTATCCGGGGTCAGGCGC
AGCGCACTCTTGCGCGGCGA

Product: periplasmic dipeptide transport protein (DBP)

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MAVQAVAGRIVQKKTDICRVTQHHSMEFNVMSSNNHASTGRGAGAVALKWGIGLVALAVAGSLQAKTLVYCSEGSPEGFN
PQLFTSGTTYDASSVPIYNRLIEFKNGSTELVPGLAESWEVSPDGKTYTFHLRKGVKWQGSKLFTPTRDFNANDVVFSFE
RQRDPSHPYHKVSGGSYEYFQGMGLPELISRVEKVDDSTVRIELNHPESPFLADLAMDFASILSAEYADAMMKAGTPEKI
DLEPLGTGPFQLMQYQKDSKILYKANKEYWGPQPKIDRLVFSITPDASVRYAKLQKNECQVMPYPNPADLARMKQDKNIT
LLEQPGLNVGYLSFNVDKKPLDNVKVRQALTMAVNKPAIIEAVYQKAGQSAKNLIPPTMWGYNDEIKDYPYDPEKAKALL
KEAGLADGFSIDLWAMPVQRPYNPNARRMAEMIQADWDKIGVKAKIVTYEWGEYLKRAKDGEHQAVMMGWTGDNGDPDNF
FATLFSCDAAKQGSNYSRWCYQPFEAVIQPARAEADQAKRAELYRQAQVIMHGQAPALIIAHSTVYEPVRKEVKGYVVDP
LGKHHFNQVSLE

Sequences:

>Translated_572_residues
MAVQAVAGRIVQKKTDICRVTQHHSMEFNVMSSNNHASTGRGAGAVALKWGIGLVALAVAGSLQAKTLVYCSEGSPEGFN
PQLFTSGTTYDASSVPIYNRLIEFKNGSTELVPGLAESWEVSPDGKTYTFHLRKGVKWQGSKLFTPTRDFNANDVVFSFE
RQRDPSHPYHKVSGGSYEYFQGMGLPELISRVEKVDDSTVRIELNHPESPFLADLAMDFASILSAEYADAMMKAGTPEKI
DLEPLGTGPFQLMQYQKDSKILYKANKEYWGPQPKIDRLVFSITPDASVRYAKLQKNECQVMPYPNPADLARMKQDKNIT
LLEQPGLNVGYLSFNVDKKPLDNVKVRQALTMAVNKPAIIEAVYQKAGQSAKNLIPPTMWGYNDEIKDYPYDPEKAKALL
KEAGLADGFSIDLWAMPVQRPYNPNARRMAEMIQADWDKIGVKAKIVTYEWGEYLKRAKDGEHQAVMMGWTGDNGDPDNF
FATLFSCDAAKQGSNYSRWCYQPFEAVIQPARAEADQAKRAELYRQAQVIMHGQAPALIIAHSTVYEPVRKEVKGYVVDP
LGKHHFNQVSLE
>Mature_571_residues
AVQAVAGRIVQKKTDICRVTQHHSMEFNVMSSNNHASTGRGAGAVALKWGIGLVALAVAGSLQAKTLVYCSEGSPEGFNP
QLFTSGTTYDASSVPIYNRLIEFKNGSTELVPGLAESWEVSPDGKTYTFHLRKGVKWQGSKLFTPTRDFNANDVVFSFER
QRDPSHPYHKVSGGSYEYFQGMGLPELISRVEKVDDSTVRIELNHPESPFLADLAMDFASILSAEYADAMMKAGTPEKID
LEPLGTGPFQLMQYQKDSKILYKANKEYWGPQPKIDRLVFSITPDASVRYAKLQKNECQVMPYPNPADLARMKQDKNITL
LEQPGLNVGYLSFNVDKKPLDNVKVRQALTMAVNKPAIIEAVYQKAGQSAKNLIPPTMWGYNDEIKDYPYDPEKAKALLK
EAGLADGFSIDLWAMPVQRPYNPNARRMAEMIQADWDKIGVKAKIVTYEWGEYLKRAKDGEHQAVMMGWTGDNGDPDNFF
ATLFSCDAAKQGSNYSRWCYQPFEAVIQPARAEADQAKRAELYRQAQVIMHGQAPALIIAHSTVYEPVRKEVKGYVVDPL
GKHHFNQVSLE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=525, Percent_Identity=81.9047619047619, Blast_Score=920, Evalue=0.0,
Organism=Escherichia coli, GI1787551, Length=505, Percent_Identity=36.2376237623762, Blast_Score=352, Evalue=3e-98,
Organism=Escherichia coli, GI1787052, Length=539, Percent_Identity=29.3135435992579, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787762, Length=504, Percent_Identity=26.1904761904762, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1789887, Length=521, Percent_Identity=26.1036468330134, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1789397, Length=541, Percent_Identity=26.6173752310536, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1787495, Length=476, Percent_Identity=24.3697478991597, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081878, Length=474, Percent_Identity=24.4725738396624, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63889; Mature: 63758

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVQAVAGRIVQKKTDICRVTQHHSMEFNVMSSNNHASTGRGAGAVALKWGIGLVALAVA
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHH
GSLQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPIYNRLIEFKNGSTELVPGLAESWE
CCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHCCC
VSPDGKTYTFHLRKGVKWQGSKLFTPTRDFNANDVVFSFERQRDPSHPYHKVSGGSYEYF
CCCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCEECCCCCCHHH
QGMGLPELISRVEKVDDSTVRIELNHPESPFLADLAMDFASILSAEYADAMMKAGTPEKI
HCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
DLEPLGTGPFQLMQYQKDSKILYKANKEYWGPQPKIDRLVFSITPDASVRYAKLQKNECQ
EEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCE
VMPYPNPADLARMKQDKNITLLEQPGLNVGYLSFNVDKKPLDNVKVRQALTMAVNKPAII
EECCCCHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHH
EAVYQKAGQSAKNLIPPTMWGYNDEIKDYPYDPEKAKALLKEAGLADGFSIDLWAMPVQR
HHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCC
PYNPNARRMAEMIQADWDKIGVKAKIVTYEWGEYLKRAKDGEHQAVMMGWTGDNGDPDNF
CCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHCCCCCCEEEEEEECCCCCCCHHH
FATLFSCDAAKQGSNYSRWCYQPFEAVIQPARAEADQAKRAELYRQAQVIMHGQAPALII
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEE
AHSTVYEPVRKEVKGYVVDPLGKHHFNQVSLE
ECHHHHHHHHHHHCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
AVQAVAGRIVQKKTDICRVTQHHSMEFNVMSSNNHASTGRGAGAVALKWGIGLVALAVA
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHH
GSLQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPIYNRLIEFKNGSTELVPGLAESWE
CCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHCCC
VSPDGKTYTFHLRKGVKWQGSKLFTPTRDFNANDVVFSFERQRDPSHPYHKVSGGSYEYF
CCCCCCEEEEEEECCCCCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCEECCCCCCHHH
QGMGLPELISRVEKVDDSTVRIELNHPESPFLADLAMDFASILSAEYADAMMKAGTPEKI
HCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
DLEPLGTGPFQLMQYQKDSKILYKANKEYWGPQPKIDRLVFSITPDASVRYAKLQKNECQ
EEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCE
VMPYPNPADLARMKQDKNITLLEQPGLNVGYLSFNVDKKPLDNVKVRQALTMAVNKPAII
EECCCCHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCHHH
EAVYQKAGQSAKNLIPPTMWGYNDEIKDYPYDPEKAKALLKEAGLADGFSIDLWAMPVQR
HHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCC
PYNPNARRMAEMIQADWDKIGVKAKIVTYEWGEYLKRAKDGEHQAVMMGWTGDNGDPDNF
CCCCCHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHCCCCCCEEEEEEECCCCCCCHHH
FATLFSCDAAKQGSNYSRWCYQPFEAVIQPARAEADQAKRAELYRQAQVIMHGQAPALII
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEE
AHSTVYEPVRKEVKGYVVDPLGKHHFNQVSLE
ECHHHHHHHHHHHCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]