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The map label for this gene is hslO

Identifier: 238921485

GI number: 238921485

Start: 3523184

End: 3524065

Strand: Direct

Name: hslO

Synonym: NT01EI_3637

Alternate gene names: 238921485

Gene position: 3523184-3524065 (Clockwise)

Preceding gene: 238921484

Following gene: 238921486

Centisome position: 92.42

GC content: 61.0

Gene sequence:

>882_bases
ATGCCCCATCACGACCAATTACATCGCTACCTGTTTGACAATCTGGCCGTACGCGGCGAGCTGGTCAACGCCAGCGCCAC
CTATGCCCGCATACTGGAAAACCACGACTACCCGGCCGCGGTGCGCGCGCTGCTGGGTGAACTGTTGGTCGCCACCACTC
TGCTGACCGCTACCCTGAAGTTCGACGGCGATATCACAGTACAGCTGCAGGGTGACGGTCCGCTGAAGCTGGCGGTGATC
AATGGCAACCATCGTCAGGAGATGCGCGGCGTCGCCCGCCTGCAGGGCGATATCGCCGATGGCAGCAGCCTGAAACACAT
GCTGGGCAACGGTATCATGGTGATCACCATTACACCGAAAGAAGGAGAGCGTTATCAGGGCGTCGTGGCGCTGGAAGGCG
ATACACTGTCCAACTGTCTGGAGGCCTACTTCATGCAGTCCGAGCAGCTGCCGACCCGCCTGTTTATGTTCACCGGGGAG
CAGGACGGTCAACCGGCGGCGGCCGGTATGCTGCTGCAGATCCTGCCGACGCAGCCCAATAACGTTGACGATCTGACTCA
CCTGTCGCACCTTACGACCACTGTTACCCCGCAGGAGCTGTTTACGCTGCCCGCCAACGAGGTGCTGTACCGCCTGTACA
ATCAGGAGCAGGTGACCCTGTTTGAGCCACAGCCGATCGCCTTCCTCTGCGGTTGCTCCCGCGGGCGCAGCGCCAGCGCG
CTGATGAGCCTGCCACCCCAGCAGCTGGAAGAGCTGTTGGCTGAGCGTGGCAGCATCGATATCCATTGCGACTACTGCGG
TAGCCACTACCTGTTCGATCGGGTCGATATCGACGCATTACGTGCCGGAGCACAGCCGGACGAAGCGGGTCAGCTACACT
AA

Upstream 100 bases:

>100_bases
TGCCACACCCGGATCGGCGTCCCGATAAAAAAGAGCGCCGCAATCTGCTTAAATTTAAATACGACCAGTCGGAATGACCG
GCGCCTGAAGAGAGAGAACT

Downstream 100 bases:

>100_bases
TAATCGTCTTTCCTCGGGGGAATCATCCCCCGTTTTTATTTATTATTTTATTTTAATTAACTCGGGGAATATTAAAGACA
GATTATTCCCTACCTCTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MPHHDQLHRYLFDNLAVRGELVNASATYARILENHDYPAAVRALLGELLVATTLLTATLKFDGDITVQLQGDGPLKLAVI
NGNHRQEMRGVARLQGDIADGSSLKHMLGNGIMVITITPKEGERYQGVVALEGDTLSNCLEAYFMQSEQLPTRLFMFTGE
QDGQPAAAGMLLQILPTQPNNVDDLTHLSHLTTTVTPQELFTLPANEVLYRLYNQEQVTLFEPQPIAFLCGCSRGRSASA
LMSLPPQQLEELLAERGSIDIHCDYCGSHYLFDRVDIDALRAGAQPDEAGQLH

Sequences:

>Translated_293_residues
MPHHDQLHRYLFDNLAVRGELVNASATYARILENHDYPAAVRALLGELLVATTLLTATLKFDGDITVQLQGDGPLKLAVI
NGNHRQEMRGVARLQGDIADGSSLKHMLGNGIMVITITPKEGERYQGVVALEGDTLSNCLEAYFMQSEQLPTRLFMFTGE
QDGQPAAAGMLLQILPTQPNNVDDLTHLSHLTTTVTPQELFTLPANEVLYRLYNQEQVTLFEPQPIAFLCGCSRGRSASA
LMSLPPQQLEELLAERGSIDIHCDYCGSHYLFDRVDIDALRAGAQPDEAGQLH
>Mature_292_residues
PHHDQLHRYLFDNLAVRGELVNASATYARILENHDYPAAVRALLGELLVATTLLTATLKFDGDITVQLQGDGPLKLAVIN
GNHRQEMRGVARLQGDIADGSSLKHMLGNGIMVITITPKEGERYQGVVALEGDTLSNCLEAYFMQSEQLPTRLFMFTGEQ
DGQPAAAGMLLQILPTQPNNVDDLTHLSHLTTTVTPQELFTLPANEVLYRLYNQEQVTLFEPQPIAFLCGCSRGRSASAL
MSLPPQQLEELLAERGSIDIHCDYCGSHYLFDRVDIDALRAGAQPDEAGQLH

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=286, Percent_Identity=65.3846153846154, Blast_Score=401, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_EDWI9 (C5BGR8)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002935000.1
- ProteinModelPortal:   C5BGR8
- GeneID:   7962145
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3637
- OMA:   AMTIDQG
- ProtClustDB:   CLSK2813697
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212
- Gene3D:   G3DSA:1.10.287.480
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32248; Mature: 32117

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHHDQLHRYLFDNLAVRGELVNASATYARILENHDYPAAVRALLGELLVATTLLTATLK
CCCHHHHHHHHHHHHHHEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEE
FDGDITVQLQGDGPLKLAVINGNHRQEMRGVARLQGDIADGSSLKHMLGNGIMVITITPK
ECCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECC
EGERYQGVVALEGDTLSNCLEAYFMQSEQLPTRLFMFTGEQDGQPAAAGMLLQILPTQPN
CCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHCEEEEEECCCCC
NVDDLTHLSHLTTTVTPQELFTLPANEVLYRLYNQEQVTLFEPQPIAFLCGCSRGRSASA
CHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCHH
LMSLPPQQLEELLAERGSIDIHCDYCGSHYLFDRVDIDALRAGAQPDEAGQLH
HHCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PHHDQLHRYLFDNLAVRGELVNASATYARILENHDYPAAVRALLGELLVATTLLTATLK
CCHHHHHHHHHHHHHHEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEE
FDGDITVQLQGDGPLKLAVINGNHRQEMRGVARLQGDIADGSSLKHMLGNGIMVITITPK
ECCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECC
EGERYQGVVALEGDTLSNCLEAYFMQSEQLPTRLFMFTGEQDGQPAAAGMLLQILPTQPN
CCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHCEEEEEECCCCC
NVDDLTHLSHLTTTVTPQELFTLPANEVLYRLYNQEQVTLFEPQPIAFLCGCSRGRSASA
CHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCHH
LMSLPPQQLEELLAERGSIDIHCDYCGSHYLFDRVDIDALRAGAQPDEAGQLH
HHCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA