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The map label for this gene is trkH [H]

Identifier: 238921413

GI number: 238921413

Start: 3466516

End: 3467961

Strand: Direct

Name: trkH [H]

Synonym: NT01EI_3564

Alternate gene names: 238921413

Gene position: 3466516-3467961 (Clockwise)

Preceding gene: 238921412

Following gene: 238921414

Centisome position: 90.93

GC content: 55.05

Gene sequence:

>1446_bases
ATGCTCAACTATCGCTCCGTGCTGTACATCCTTGGGATGATGCTATCCAAAGTGGCGCTGCTGATGTACGTGCCGCTGCT
GTATGCCCTGCTCACTGGCACCGGTGGGGTTTACGAATTTCTGCAGGCGGTGATCATCACCCACTTGATCGCCCTGTTTT
TGATCGCCCAAGGTCGCAGCCAGAAATTCTACCTGCGTATCCGCGATATGTTTCTGACCACGACCCTGGCGTGGCTGACG
GCCTGCTGCTTCGGCGCGCTGCCCTTTGTGTTCATCAAACATATCACCTTTACTGATGCCTTCTTTGAAACCATGTCTGG
GCTGACCACCACCGGCTCTTCGGTGCTGTCCAATCTGAACCAGATGGAACCCAGCGTCTTACTGTGGCGCTCACTGCTGC
AGTGGATGGGCGGCGTCGGGTTTATCGTGATGGCGGTCGCCATTCTGCCGTTTCTGGACGTCGGCGGTATGCGCCTGTTC
CATACCGAATCCTCAGACTGGTCAGAAAAATCCTCGCCGCGGATGAAAGACGTCGCCAAAAGCATCATGGCGGTCTATGC
GGTGCTGACGTTCCTCTGCTACCTCGGCTATCGCTACGCAGGGATGAGCAACTTCGATGCGGTCAACCATGCCTTCGCAA
CCATCTCTACCGGCGGATTTTCAACCAATGATAAATCCATGGCCGCGTACTCCGTGCTGGCGCAGTGGAACGCAATCCTA
TTTATGTTCCTCGGATCTCTGCCATTTCTGCTGTTCGTACAGGCGCTGCGTCAGCGCAGTCTCAGAACCCTGATGCGCGA
CCAGCAATTGGTCGGTTTCAGTCGCTTCGTACTGGTTGTCGGACTGATCCTCACGCTGTGGCTATGGCATAAACACATCT
TTGATTTTGAAGATAGCCTGCGCATCGCATTTTTCAATTTGATCAATATCCTGTCGACCACAGGCTACTCTCTGGGTAAT
TTCGATCAGTGGACGCCATTCACCACGGTACTGTTTGCCTCTTTGATGCTGTTGGGGGGCTGCTCCGGCTCTACTGCCGG
CGGGATCAAGATGTTCCGAGTGCAGATTGGTTTCGAAAGCCTGCATATTGAGGTGCGCAAACTGATCCACCCGAATGCCG
TTTTTCCACGTCGCTATAACAACCGTCCTATCACCAACGAAGTTAGCCGCTCGGTGATCGCCTTTATGATGGCGTTTATT
GCGATCACTATGTTGATTGCCGCCATCCTCGGGCTGTGCGGTGTTGATGCTCTTTCTTCGATCACCGGTGCCATGAGCGC
GATGGCCAACGTCGGCCCAGGAATGGGGCCTCTCATCGGTCCCAGCGGCAACTTCGCTCCGCTACCCGACGTTGCCAAGT
GGGCTCTGTCGCTCGGCATGCTGCTTGGGCGACTCGAGGTCATGACCATGCTGGTGCTGTTCTTCCCCAGTTTCTGGCGA
CACTGA

Upstream 100 bases:

>100_bases
AACAGGGAGATCACGTGATCATGTTCCTGACGGACAAGAAATTTATATCCGACGTGGAGCGCCTGTTTCAGCCAAGTCCT
TTCTTTTTGTAACTACAGCT

Downstream 100 bases:

>100_bases
AGCATCTTGATGCTCGTCTTCTAGCAAAGGGGCGGCAAGTGATTACACTTGCAGTATGAATAATGTGGTTTGGCGATAGT
TATGAGGCTACTTAAAGAGT

Product: hypothetical protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MLNYRSVLYILGMMLSKVALLMYVPLLYALLTGTGGVYEFLQAVIITHLIALFLIAQGRSQKFYLRIRDMFLTTTLAWLT
ACCFGALPFVFIKHITFTDAFFETMSGLTTTGSSVLSNLNQMEPSVLLWRSLLQWMGGVGFIVMAVAILPFLDVGGMRLF
HTESSDWSEKSSPRMKDVAKSIMAVYAVLTFLCYLGYRYAGMSNFDAVNHAFATISTGGFSTNDKSMAAYSVLAQWNAIL
FMFLGSLPFLLFVQALRQRSLRTLMRDQQLVGFSRFVLVVGLILTLWLWHKHIFDFEDSLRIAFFNLINILSTTGYSLGN
FDQWTPFTTVLFASLMLLGGCSGSTAGGIKMFRVQIGFESLHIEVRKLIHPNAVFPRRYNNRPITNEVSRSVIAFMMAFI
AITMLIAAILGLCGVDALSSITGAMSAMANVGPGMGPLIGPSGNFAPLPDVAKWALSLGMLLGRLEVMTMLVLFFPSFWR
H

Sequences:

>Translated_481_residues
MLNYRSVLYILGMMLSKVALLMYVPLLYALLTGTGGVYEFLQAVIITHLIALFLIAQGRSQKFYLRIRDMFLTTTLAWLT
ACCFGALPFVFIKHITFTDAFFETMSGLTTTGSSVLSNLNQMEPSVLLWRSLLQWMGGVGFIVMAVAILPFLDVGGMRLF
HTESSDWSEKSSPRMKDVAKSIMAVYAVLTFLCYLGYRYAGMSNFDAVNHAFATISTGGFSTNDKSMAAYSVLAQWNAIL
FMFLGSLPFLLFVQALRQRSLRTLMRDQQLVGFSRFVLVVGLILTLWLWHKHIFDFEDSLRIAFFNLINILSTTGYSLGN
FDQWTPFTTVLFASLMLLGGCSGSTAGGIKMFRVQIGFESLHIEVRKLIHPNAVFPRRYNNRPITNEVSRSVIAFMMAFI
AITMLIAAILGLCGVDALSSITGAMSAMANVGPGMGPLIGPSGNFAPLPDVAKWALSLGMLLGRLEVMTMLVLFFPSFWR
H
>Mature_481_residues
MLNYRSVLYILGMMLSKVALLMYVPLLYALLTGTGGVYEFLQAVIITHLIALFLIAQGRSQKFYLRIRDMFLTTTLAWLT
ACCFGALPFVFIKHITFTDAFFETMSGLTTTGSSVLSNLNQMEPSVLLWRSLLQWMGGVGFIVMAVAILPFLDVGGMRLF
HTESSDWSEKSSPRMKDVAKSIMAVYAVLTFLCYLGYRYAGMSNFDAVNHAFATISTGGFSTNDKSMAAYSVLAQWNAIL
FMFLGSLPFLLFVQALRQRSLRTLMRDQQLVGFSRFVLVVGLILTLWLWHKHIFDFEDSLRIAFFNLINILSTTGYSLGN
FDQWTPFTTVLFASLMLLGGCSGSTAGGIKMFRVQIGFESLHIEVRKLIHPNAVFPRRYNNRPITNEVSRSVIAFMMAFI
AITMLIAAILGLCGVDALSSITGAMSAMANVGPGMGPLIGPSGNFAPLPDVAKWALSLGMLLGRLEVMTMLVLFFPSFWR
H

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=489, Percent_Identity=36.40081799591, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1787626, Length=427, Percent_Identity=32.3185011709602, Blast_Score=235, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53454; Mature: 53454

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure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C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]