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The map label for this gene is kch [H]

Identifier: 238921331

GI number: 238921331

Start: 3370538

End: 3371824

Strand: Direct

Name: kch [H]

Synonym: NT01EI_3475

Alternate gene names: 238921331

Gene position: 3370538-3371824 (Clockwise)

Preceding gene: 238921330

Following gene: 238921339

Centisome position: 88.41

GC content: 59.36

Gene sequence:

>1287_bases
ATGAAAAAACTGTTCCACCGCGTATGTAGCCTGTTTAAGCCTTCATGGTGTCTGGCGCTGCTGGTTGCCCTTGAGGGCTA
TCTGTTTGCCGAACCGGTGGTCATCCAGGCATTCCGCTATGTTCCCGGCGCAATACAGTCATTCCGCAGCTGGAGAGAAG
CACTCTCCATGGTTAATCTGCTGGAGATCCCCCGCGTCATGCTGGGGGTAGCACTGATGCTGATGTCCATCGGTATGCTG
TTACGCGCACGCGTCGCCTGGGCGTTTACCCTGCTGCTGCTGATCGCCATCGCCGTGCTGTCGCTGATCCAGGATCCCAG
TCTGCCCATCTGGCAGGCACAGGATCTGGTACGCCTGCTGTGGCACGATCTCAGGGTGTGGAACTGGCAGGACATCTCGC
TGACCAATCTGGAGGGCTACAGCCATAACCTGACGCTGTATACCCTGGTTCTGATCGCCCTACTGATACGCTACTGGGAG
CGATTTGACCGGGCCAGCCTGGCTGCCGGCAGCCTGTTTGCCCTGGTCAGCTTTGCCTCGTTGCTCATCTACGCCATCTT
TGGCTCGCTGTATCTGGGCAACGAGTTCAAGCCGCCGATCCTGGACGTGGTCACCGCGTTCTACTTTTCAGTCGTCAGCA
TGTCCACCGTCGGCTTCGGCGATATCGTTCCCTATACCGCCACCGCGCGGCTGTTCACCATCTCGGTGATCGTGATGGGA
ATTACGGTATTCGCCACGTCAATCAGCGCCATCATCGGTCCGGTGATCGGCGGCAACCTTAAACGCATGGTTAAAGGCAG
GATCTCTCACGTGATGCGCAAAAACCACTTTATCATCGCCGGCGCGTCGCCGCTGGCGCTCAGTATCTACAAGGGGCTGA
AGGAGCGCGGCGATGCGATCACCGCCATCGTCCCGATGAGCGTCGCCCACGAGTACCCGCAGGATGCTGATGTGGTGGTC
GGCGATCCCTCCAGCGCACAGGTGCTGACGGAGGCCGGCGCCGCGCGTGCGCTGTACATTCTGGCGCTGCGCGAGGACGA
TGCGGAAAACGCCTTTATCGTCCTGGCAGCCAAAGAGGTGGCAGGCGGCGCCACCAAGACCATTTCGCTGGTCAACGCCA
GTAAGCATCTGCAGAAGATCAAGCGGGTACAGCCAGATATGGTGTTCTCGCTGCAGCTGCTGGGCAGCGAACTGCTGGTG
CGCACCCTGAGCGGCGAAGCCATCGACAACAAGCTGGTTACGCAGCTGTTCTTTGGCAATGCCGAGGTAGCAGGGGAGCA
GGACTGA

Upstream 100 bases:

>100_bases
GAGATTTATCCGCCCACAGACCCGCCCTTAAGGCGGGTCTCCCTATCCATTACCGCCCATACGCGTTACACTTTTTATTA
TTTCCTTAACGCGCATCGCT

Downstream 100 bases:

>100_bases
CCTCCGTCCGCGCCCCCATGGCCGCTGCGTTACCCCCATCGGCGGGGGTAACGCAGCGGTCAGCCCATTCGGGCTGACCG
ATAGATATCAGCGACGTAGC

Product: voltage-gated potassium channel

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKKLFHRVCSLFKPSWCLALLVALEGYLFAEPVVIQAFRYVPGAIQSFRSWREALSMVNLLEIPRVMLGVALMLMSIGML
LRARVAWAFTLLLLIAIAVLSLIQDPSLPIWQAQDLVRLLWHDLRVWNWQDISLTNLEGYSHNLTLYTLVLIALLIRYWE
RFDRASLAAGSLFALVSFASLLIYAIFGSLYLGNEFKPPILDVVTAFYFSVVSMSTVGFGDIVPYTATARLFTISVIVMG
ITVFATSISAIIGPVIGGNLKRMVKGRISHVMRKNHFIIAGASPLALSIYKGLKERGDAITAIVPMSVAHEYPQDADVVV
GDPSSAQVLTEAGAARALYILALREDDAENAFIVLAAKEVAGGATKTISLVNASKHLQKIKRVQPDMVFSLQLLGSELLV
RTLSGEAIDNKLVTQLFFGNAEVAGEQD

Sequences:

>Translated_428_residues
MKKLFHRVCSLFKPSWCLALLVALEGYLFAEPVVIQAFRYVPGAIQSFRSWREALSMVNLLEIPRVMLGVALMLMSIGML
LRARVAWAFTLLLLIAIAVLSLIQDPSLPIWQAQDLVRLLWHDLRVWNWQDISLTNLEGYSHNLTLYTLVLIALLIRYWE
RFDRASLAAGSLFALVSFASLLIYAIFGSLYLGNEFKPPILDVVTAFYFSVVSMSTVGFGDIVPYTATARLFTISVIVMG
ITVFATSISAIIGPVIGGNLKRMVKGRISHVMRKNHFIIAGASPLALSIYKGLKERGDAITAIVPMSVAHEYPQDADVVV
GDPSSAQVLTEAGAARALYILALREDDAENAFIVLAAKEVAGGATKTISLVNASKHLQKIKRVQPDMVFSLQLLGSELLV
RTLSGEAIDNKLVTQLFFGNAEVAGEQD
>Mature_428_residues
MKKLFHRVCSLFKPSWCLALLVALEGYLFAEPVVIQAFRYVPGAIQSFRSWREALSMVNLLEIPRVMLGVALMLMSIGML
LRARVAWAFTLLLLIAIAVLSLIQDPSLPIWQAQDLVRLLWHDLRVWNWQDISLTNLEGYSHNLTLYTLVLIALLIRYWE
RFDRASLAAGSLFALVSFASLLIYAIFGSLYLGNEFKPPILDVVTAFYFSVVSMSTVGFGDIVPYTATARLFTISVIVMG
ITVFATSISAIIGPVIGGNLKRMVKGRISHVMRKNHFIIAGASPLALSIYKGLKERGDAITAIVPMSVAHEYPQDADVVV
GDPSSAQVLTEAGAARALYILALREDDAENAFIVLAAKEVAGGATKTISLVNASKHLQKIKRVQPDMVFSLQLLGSELLV
RTLSGEAIDNKLVTQLFFGNAEVAGEQD

Specific function: May play a role in the defense against osmotic shock [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=369, Percent_Identity=40.9214092140921, Blast_Score=254, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 47030; Mature: 47030

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFHRVCSLFKPSWCLALLVALEGYLFAEPVVIQAFRYVPGAIQSFRSWREALSMVNL
CHHHHHHHHHHHCCHHHHHHHHHHHCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LEIPRVMLGVALMLMSIGMLLRARVAWAFTLLLLIAIAVLSLIQDPSLPIWQAQDLVRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
WHDLRVWNWQDISLTNLEGYSHNLTLYTLVLIALLIRYWERFDRASLAAGSLFALVSFAS
HHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIYAIFGSLYLGNEFKPPILDVVTAFYFSVVSMSTVGFGDIVPYTATARLFTISVIVMG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
ITVFATSISAIIGPVIGGNLKRMVKGRISHVMRKNHFIIAGASPLALSIYKGLKERGDAI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCEE
TAIVPMSVAHEYPQDADVVVGDPSSAQVLTEAGAARALYILALREDDAENAFIVLAAKEV
EEEEEHHHHHCCCCCCCEEEECCCCHHHHHHCCCCEEEEEEEEECCCCCCEEEEEEEHHH
AGGATKTISLVNASKHLQKIKRVQPDMVFSLQLLGSELLVRTLSGEAIDNKLVTQLFFGN
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
AEVAGEQD
CCCCCCCC
>Mature Secondary Structure
MKKLFHRVCSLFKPSWCLALLVALEGYLFAEPVVIQAFRYVPGAIQSFRSWREALSMVNL
CHHHHHHHHHHHCCHHHHHHHHHHHCHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LEIPRVMLGVALMLMSIGMLLRARVAWAFTLLLLIAIAVLSLIQDPSLPIWQAQDLVRLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
WHDLRVWNWQDISLTNLEGYSHNLTLYTLVLIALLIRYWERFDRASLAAGSLFALVSFAS
HHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIYAIFGSLYLGNEFKPPILDVVTAFYFSVVSMSTVGFGDIVPYTATARLFTISVIVMG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
ITVFATSISAIIGPVIGGNLKRMVKGRISHVMRKNHFIIAGASPLALSIYKGLKERGDAI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCEE
TAIVPMSVAHEYPQDADVVVGDPSSAQVLTEAGAARALYILALREDDAENAFIVLAAKEV
EEEEEHHHHHCCCCCCCEEEECCCCHHHHHHCCCCEEEEEEEEECCCCCCEEEEEEEHHH
AGGATKTISLVNASKHLQKIKRVQPDMVFSLQLLGSELLVRTLSGEAIDNKLVTQLFFGN
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
AEVAGEQD
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8170937; 9097039; 9278503 [H]