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The map label for this gene is aaeR [H]

Identifier: 238921339

GI number: 238921339

Start: 3377564

End: 3378526

Strand: Direct

Name: aaeR [H]

Synonym: NT01EI_3483

Alternate gene names: 238921339

Gene position: 3377564-3378526 (Clockwise)

Preceding gene: 238921331

Following gene: 238921350

Centisome position: 88.6

GC content: 61.27

Gene sequence:

>963_bases
ATGGTTTTAAATGCGGCTACCACCATTAAGACAGGATTAAAAATGGAGCGATTAAAGCGTATGGCCATCTTCGCCCGGGT
GGTCGAATGCGGCTCATTTACCGGCGCCGCAGCGCAGCTGGCGATGAGCGTATCATCCATCAGCCAGACCATTACCAAGC
TGGAGCAATCTCTGCAGATCAGGCTGCTCAACCGCAGTACCCGCCGCATCAGCCTGACCGAGGCCGGACGCATCTATTAT
CAGGGCTGCCGTAAGATGCTGCAGGAGGCCCAGGAGGTGCACGAACAGCTGTATGCCTACAACAATACTCCCAGCGGAAC
CCTGCGCATCGGTTGCTCGGCCACCATGGCGCAAAACGTTCTGGCACCGATCAGCGCCAGGATGCTGGCCGAATACCCCG
GACTGTCGGTCAATCTGGTCACCGGCGTCCCGGCGCCCGATCTGATCGCCGACGGGCTGGATCTGGTGGTCCGCGCCGGC
GATCTACAGGACTCACGCCTGTTCTGCCGCTCCCTGGGCGCCATGCCCATGGTGATCTGCGCCGCCAAATGCTATCTGCA
GCGGCACGGAACTCCGGAGAACCCCGCCGAGCTGGGCAGCTATAGCTGGCTCAACTTTAGCGGCCAGCCCGCCCCCGAAC
TCACGCTGACCGCCCCGGAGGGGGAGTCGCTACGGCTGATGCCCAGCGGACGTTTCCATACCAATGATGCCCAGACCCTG
CTGAGCTGGCTGAATGCCGGGGCCGGGATCACCTATCTGCCACTGATGTGGGTGATCGATGCGGTGCGGCGTAAAGAGGT
CGAGATCCTGTTTCCCCAGTACCAGTCCCCCCCGCGCCCGGTATATGCGCTATACGCCCAGAAAGCGCACCTGCCCATCA
AGCTGCGTCTCTGCCTGGAGTACCTGAGCGACTACTTTGCCCAGATGGCGGATACCTTCCGCGATACCCGCCAGGAGAAA
TAG

Upstream 100 bases:

>100_bases
GGGATATATAATCTGTGACGCAAATCACTTTTTACTATAAATAAACAATCATCGGTGATTATCTATTATTGACAGAGAAA
AACGAACATAAAACATACAA

Downstream 100 bases:

>100_bases
CGCGGGCCGGCAAAGGCCGGCCCGCGGGAGATACCGTGGCGAATCGCGCCGAACTCAGGCGGTGCCGCCGACGGTCATCG
CATCCAGCCTCAGCGTCGGC

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MVLNAATTIKTGLKMERLKRMAIFARVVECGSFTGAAAQLAMSVSSISQTITKLEQSLQIRLLNRSTRRISLTEAGRIYY
QGCRKMLQEAQEVHEQLYAYNNTPSGTLRIGCSATMAQNVLAPISARMLAEYPGLSVNLVTGVPAPDLIADGLDLVVRAG
DLQDSRLFCRSLGAMPMVICAAKCYLQRHGTPENPAELGSYSWLNFSGQPAPELTLTAPEGESLRLMPSGRFHTNDAQTL
LSWLNAGAGITYLPLMWVIDAVRRKEVEILFPQYQSPPRPVYALYAQKAHLPIKLRLCLEYLSDYFAQMADTFRDTRQEK

Sequences:

>Translated_320_residues
MVLNAATTIKTGLKMERLKRMAIFARVVECGSFTGAAAQLAMSVSSISQTITKLEQSLQIRLLNRSTRRISLTEAGRIYY
QGCRKMLQEAQEVHEQLYAYNNTPSGTLRIGCSATMAQNVLAPISARMLAEYPGLSVNLVTGVPAPDLIADGLDLVVRAG
DLQDSRLFCRSLGAMPMVICAAKCYLQRHGTPENPAELGSYSWLNFSGQPAPELTLTAPEGESLRLMPSGRFHTNDAQTL
LSWLNAGAGITYLPLMWVIDAVRRKEVEILFPQYQSPPRPVYALYAQKAHLPIKLRLCLEYLSDYFAQMADTFRDTRQEK
>Mature_320_residues
MVLNAATTIKTGLKMERLKRMAIFARVVECGSFTGAAAQLAMSVSSISQTITKLEQSLQIRLLNRSTRRISLTEAGRIYY
QGCRKMLQEAQEVHEQLYAYNNTPSGTLRIGCSATMAQNVLAPISARMLAEYPGLSVNLVTGVPAPDLIADGLDLVVRAG
DLQDSRLFCRSLGAMPMVICAAKCYLQRHGTPENPAELGSYSWLNFSGQPAPELTLTAPEGESLRLMPSGRFHTNDAQTL
LSWLNAGAGITYLPLMWVIDAVRRKEVEILFPQYQSPPRPVYALYAQKAHLPIKLRLCLEYLSDYFAQMADTFRDTRQEK

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=301, Percent_Identity=68.1063122923588, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=29.4314381270903, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786401, Length=299, Percent_Identity=31.1036789297659, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=27.1477663230241, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87081978, Length=298, Percent_Identity=27.1812080536913, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=29.2096219931272, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787589, Length=278, Percent_Identity=28.0575539568345, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788481, Length=146, Percent_Identity=33.5616438356164, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=34.7107438016529, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788706, Length=174, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787601, Length=126, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786448, Length=131, Percent_Identity=31.2977099236641, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788297, Length=144, Percent_Identity=29.1666666666667, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35498; Mature: 35498

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLNAATTIKTGLKMERLKRMAIFARVVECGSFTGAAAQLAMSVSSISQTITKLEQSLQI
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLNRSTRRISLTEAGRIYYQGCRKMLQEAQEVHEQLYAYNNTPSGTLRIGCSATMAQNV
HEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
LAPISARMLAEYPGLSVNLVTGVPAPDLIADGLDLVVRAGDLQDSRLFCRSLGAMPMVIC
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCHHHEEECCCCCHHHHHHHHHCCHHHHHH
AAKCYLQRHGTPENPAELGSYSWLNFSGQPAPELTLTAPEGESLRLMPSGRFHTNDAQTL
HHHHHHHHCCCCCCHHHHCCEEEECCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHH
LSWLNAGAGITYLPLMWVIDAVRRKEVEILFPQYQSPPRPVYALYAQKAHLPIKLRLCLE
HHHHHCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEHHCCCCCCHHHHHHH
YLSDYFAQMADTFRDTRQEK
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVLNAATTIKTGLKMERLKRMAIFARVVECGSFTGAAAQLAMSVSSISQTITKLEQSLQI
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLNRSTRRISLTEAGRIYYQGCRKMLQEAQEVHEQLYAYNNTPSGTLRIGCSATMAQNV
HEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
LAPISARMLAEYPGLSVNLVTGVPAPDLIADGLDLVVRAGDLQDSRLFCRSLGAMPMVIC
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCHHHEEECCCCCHHHHHHHHHCCHHHHHH
AAKCYLQRHGTPENPAELGSYSWLNFSGQPAPELTLTAPEGESLRLMPSGRFHTNDAQTL
HHHHHHHHCCCCCCHHHHCCEEEECCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHH
LSWLNAGAGITYLPLMWVIDAVRRKEVEILFPQYQSPPRPVYALYAQKAHLPIKLRLCLE
HHHHHCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEHHCCCCCCHHHHHHH
YLSDYFAQMADTFRDTRQEK
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]