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The map label for this gene is selA

Identifier: 238921328

GI number: 238921328

Start: 3365479

End: 3366870

Strand: Direct

Name: selA

Synonym: NT01EI_3472

Alternate gene names: 238921328

Gene position: 3365479-3366870 (Clockwise)

Preceding gene: 238921327

Following gene: 238921329

Centisome position: 88.28

GC content: 68.32

Gene sequence:

>1392_bases
ATGAGTTCAGATAGTCAGGTGCTTTACAGCCAAATCCCCGCGATCGATACCCTGCTGCGCACGCCCGCGTGCGCAGCCCT
ACAGGCGCAGTATGGCAGTCAGCTGGTTACCCAGGCCCTGCGTTCGCTGCAGCAGCAGGCCCGTCACGCCATCCAGCGGC
AGCAGGCGTTGCCTGACTGGTGCGTCGACTGGGGTGTGGCCTGCACCCGGCGGCTCGCTGAGACGCTGCAACCGGCCATG
CGTCGGGTCTTTAACCTGACCGGCACCGTCCTGCACACCAATCTTGGCCGGGCACTGCTGCCCGATACGGCGATCGCGGC
AGCGGCCGGGGCGATGGGTGCCCCGGTCACCCTGGAGTACGATCTGGACGACGCGGGGCGCGGCCACCGCGATCGCGCTA
TCGCCGATCGGCTGTGCGCCCTGACCGGTGCCGAAGACGCCTGTATCGTTAACAATAACGCGGCAGCGGTGCTGCTGATG
CTGGCGACCCTGGCGCCGGGGCGCGACGTGATCGTCTCGCGCGGTGAGCTGGTGGAGATCGGCGGTGCGTTCCGTATTCC
CGACGTCATGACCCAGGCCGGCTGCCGTCTGCGCGAGGTGGGCACCACCAACCGCACCCACCTGCACGACTACCGCCAGG
CCATCGGTGAGCACAGTGCGCTATTGATGAAGGTGCACACCAGCAACTACGCTATCGCCGGGTTCACCGCCGCCGTCAGC
GAGGCCGAGCTGGCTGCCCTGGGCCAGGAGTATGGTCTGCCGGTCATCAGTGATCTCGGCAGCGGATCGCTGCTGGACAT
GGCCCACTACGGTCTGCCCGCCGAGCCAATGCCGCAGCGTATGCTGGCCGATGGCGTCGATCTGGTCAGCTTCTCCGGTG
ACAAGCTGCTCGGCGGTCCCCAGGCCGGGATCATTGTTGGCCGCCGGGAGCTGATCCACCGTCTGCAGCGCCATCCGCTC
AAGCGCGCCCTGCGCTGCGGCAAGATGACGCTGGCGGCGCTGGACGCCACGTTGCAGCTGTACCAGCAGCCGGAGAAGCT
GCGGCAGGCGCTGCCCACCCTGCGCCATCTGACGCGGGAGGCGAGCGAGATCGCCGCCTGCGGCGAGCGGTTGCTGGCCC
GCCTGCGCCCCCACTATGAGGAGGCGTTCGTCCTGACGCTGGAGCCCTGCCTGTCGCAGATCGGCAGCGGATCGCTGCCG
GTGGATCGCCTGCCGAGCCATGCGATCACCCTGACCCCGCGTGACGGTCGCGGCGGCACCCTGACGGCGCTGGCCGACCG
CTGGCGCGCGCTGCCCTGTCCGGTCATCGGGCGACTGCAAGAGGGCAAACTGTGGCTCGATCTGCGCTGTCTGGACGATG
AGCAGGCGCTGCTCCAGGAGCTGTGCCAATGA

Upstream 100 bases:

>100_bases
GCGCACCGCGCCACCGGCCAACTAGGCTGTATTCCTGCCCCGTCAGCCTTTATCATGGGGGTCATTCGCCCCGCGCAGAT
TAAAGGTACGGAACAGTTCA

Downstream 100 bases:

>100_bases
TCATCGCCACCGCAGGACACGTTGATCACGGCAAAACCACCCTGCTGCGCGCCCTGACCGGCATCGATACCGATCGCCTG
CCGGAGGAGAAGCGCCGCGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSSDSQVLYSQIPAIDTLLRTPACAALQAQYGSQLVTQALRSLQQQARHAIQRQQALPDWCVDWGVACTRRLAETLQPAM
RRVFNLTGTVLHTNLGRALLPDTAIAAAAGAMGAPVTLEYDLDDAGRGHRDRAIADRLCALTGAEDACIVNNNAAAVLLM
LATLAPGRDVIVSRGELVEIGGAFRIPDVMTQAGCRLREVGTTNRTHLHDYRQAIGEHSALLMKVHTSNYAIAGFTAAVS
EAELAALGQEYGLPVISDLGSGSLLDMAHYGLPAEPMPQRMLADGVDLVSFSGDKLLGGPQAGIIVGRRELIHRLQRHPL
KRALRCGKMTLAALDATLQLYQQPEKLRQALPTLRHLTREASEIAACGERLLARLRPHYEEAFVLTLEPCLSQIGSGSLP
VDRLPSHAITLTPRDGRGGTLTALADRWRALPCPVIGRLQEGKLWLDLRCLDDEQALLQELCQ

Sequences:

>Translated_463_residues
MSSDSQVLYSQIPAIDTLLRTPACAALQAQYGSQLVTQALRSLQQQARHAIQRQQALPDWCVDWGVACTRRLAETLQPAM
RRVFNLTGTVLHTNLGRALLPDTAIAAAAGAMGAPVTLEYDLDDAGRGHRDRAIADRLCALTGAEDACIVNNNAAAVLLM
LATLAPGRDVIVSRGELVEIGGAFRIPDVMTQAGCRLREVGTTNRTHLHDYRQAIGEHSALLMKVHTSNYAIAGFTAAVS
EAELAALGQEYGLPVISDLGSGSLLDMAHYGLPAEPMPQRMLADGVDLVSFSGDKLLGGPQAGIIVGRRELIHRLQRHPL
KRALRCGKMTLAALDATLQLYQQPEKLRQALPTLRHLTREASEIAACGERLLARLRPHYEEAFVLTLEPCLSQIGSGSLP
VDRLPSHAITLTPRDGRGGTLTALADRWRALPCPVIGRLQEGKLWLDLRCLDDEQALLQELCQ
>Mature_462_residues
SSDSQVLYSQIPAIDTLLRTPACAALQAQYGSQLVTQALRSLQQQARHAIQRQQALPDWCVDWGVACTRRLAETLQPAMR
RVFNLTGTVLHTNLGRALLPDTAIAAAAGAMGAPVTLEYDLDDAGRGHRDRAIADRLCALTGAEDACIVNNNAAAVLLML
ATLAPGRDVIVSRGELVEIGGAFRIPDVMTQAGCRLREVGTTNRTHLHDYRQAIGEHSALLMKVHTSNYAIAGFTAAVSE
AELAALGQEYGLPVISDLGSGSLLDMAHYGLPAEPMPQRMLADGVDLVSFSGDKLLGGPQAGIIVGRRELIHRLQRHPLK
RALRCGKMTLAALDATLQLYQQPEKLRQALPTLRHLTREASEIAACGERLLARLRPHYEEAFVLTLEPCLSQIGSGSLPV
DRLPSHAITLTPRDGRGGTLTALADRWRALPCPVIGRLQEGKLWLDLRCLDDEQALLQELCQ

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family

Homologues:

Organism=Escherichia coli, GI2367248, Length=463, Percent_Identity=65.2267818574514, Blast_Score=581, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SELA_EDWI9 (C5BC01)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934843.1
- GeneID:   7962470
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3472
- OMA:   KRGDRDD
- ProtClustDB:   PRK04311
- GO:   GO:0005737
- HAMAP:   MF_00423
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534
- Gene3D:   G3DSA:3.40.640.10
- TIGRFAMs:   TIGR00474

Pfam domain/function: PF03841 SelA; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.9.1.1

Molecular weight: Translated: 50152; Mature: 50021

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDSQVLYSQIPAIDTLLRTPACAALQAQYGSQLVTQALRSLQQQARHAIQRQQALPDW
CCCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
CVDWGVACTRRLAETLQPAMRRVFNLTGTVLHTNLGRALLPDTAIAAAAGAMGAPVTLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHCCCCCCEEEEE
DLDDAGRGHRDRAIADRLCALTGAEDACIVNNNAAAVLLMLATLAPGRDVIVSRGELVEI
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCEEECCCCEEEE
GGAFRIPDVMTQAGCRLREVGTTNRTHLHDYRQAIGEHSALLMKVHTSNYAIAGFTAAVS
CCCCCCHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEHHHHHHH
EAELAALGQEYGLPVISDLGSGSLLDMAHYGLPAEPMPQRMLADGVDLVSFSGDKLLGGP
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHCCCCCCCCCHHHHHCCCCEEECCCCCCCCCC
QAGIIVGRRELIHRLQRHPLKRALRCGKMTLAALDATLQLYQQPEKLRQALPTLRHLTRE
CCCEEECHHHHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ASEIAACGERLLARLRPHYEEAFVLTLEPCLSQIGSGSLPVDRLPSHAITLTPRDGRGGT
HHHHHHHHHHHHHHHCCCCHHEEEEEHHHHHHHCCCCCCCHHHCCCCEEEEECCCCCCCC
LTALADRWRALPCPVIGRLQEGKLWLDLRCLDDEQALLQELCQ
HHHHHHHHCCCCCHHHCCCCCCCEEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure 
SSDSQVLYSQIPAIDTLLRTPACAALQAQYGSQLVTQALRSLQQQARHAIQRQQALPDW
CCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
CVDWGVACTRRLAETLQPAMRRVFNLTGTVLHTNLGRALLPDTAIAAAAGAMGAPVTLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHCCCCCCEEEEE
DLDDAGRGHRDRAIADRLCALTGAEDACIVNNNAAAVLLMLATLAPGRDVIVSRGELVEI
CCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCEEECCCCEEEE
GGAFRIPDVMTQAGCRLREVGTTNRTHLHDYRQAIGEHSALLMKVHTSNYAIAGFTAAVS
CCCCCCHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEHHHHHHH
EAELAALGQEYGLPVISDLGSGSLLDMAHYGLPAEPMPQRMLADGVDLVSFSGDKLLGGP
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHCCCCCCCCCHHHHHCCCCEEECCCCCCCCCC
QAGIIVGRRELIHRLQRHPLKRALRCGKMTLAALDATLQLYQQPEKLRQALPTLRHLTRE
CCCEEECHHHHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ASEIAACGERLLARLRPHYEEAFVLTLEPCLSQIGSGSLPVDRLPSHAITLTPRDGRGGT
HHHHHHHHHHHHHHHCCCCHHEEEEEHHHHHHHCCCCCCCHHHCCCCEEEEECCCCCCCC
LTALADRWRALPCPVIGRLQEGKLWLDLRCLDDEQALLQELCQ
HHHHHHHHCCCCCHHHCCCCCCCEEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA