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The map label for this gene is cvrA [H]

Identifier: 238921289

GI number: 238921289

Start: 3319020

End: 3320834

Strand: Direct

Name: cvrA [H]

Synonym: NT01EI_3432

Alternate gene names: 238921289

Gene position: 3319020-3320834 (Clockwise)

Preceding gene: 238921284

Following gene: 238921290

Centisome position: 87.06

GC content: 62.87

Gene sequence:

>1815_bases
ATGGCGTTATCTACCCCGCTGATGTTGGTGTTGATTGGGTTAAGCGCCCTTCTGGCACAATGGGCCGCCTGGTCACTGCG
TCTACCGGCCATACTGCTGTTGCTCTTGTTTGGGGTTATTCTCGGACCGATCACCCACCTGGTACAGCCAGACCGGCTAT
TTGGCGAGCTGTTGTTCCCTCTGGTCTCCCTATCGGTGGCGATCATCCTGTTCGAGGGCGCCTTAACACTGCGCCTGGGG
GAGATCCGCGGTCTGGGCGGCGTCGTGCGTAACCTGGTCAGCATCGGTATGCTGACCACCTTTGCCGTCATCGGTCTCGC
CTGTTGGTGGCTGCTGCGGCTGCCGCCGGAGTTGGCGGCGCTGATCGGCGCGGTGACCGTAGTCACCGGTCCCACGGTGA
TAGCCCCCCTGATGCGCGTAGTACGCCCAAACGCCAGCGTCAACCAGGTGCTGCGCTGGGAGGGGATCATCATCGATCCC
ATCGGGGCCATCTTCACGCTGTTGGTCTTCGAATTCATCGTCCTGCAGCAAAGCGCCCAATCTTACGGCCATCTTTTCTG
GACCCTGGGCAGCACGGTACTGGTCGGTCTGCTCGTCGGGCTGGCGTGTGGCTATCTTATCGGCGTCAGCCTGCGCCGCG
CCTGGGTGCCGGGTTACCTGCAAAACCTGGCGGTCCTCGCCTCGATGCTGGCCGCGTTCGGCCTGTCAAACGCCATCGCC
GATGAGTCGGGACTACTGACCGTCACGGTGATCGGCATACTGCTGGCCAACATGCGCAATGTCGATACCAGCGACATCCT
CGCCTTTAAGGAGGAGCTCTCCGTCATCCTGATCTCCGCCCTCTTCATCATCCTGGCGGCGCGCCTCGATATCGCGGCGC
TCTGGCAAATGGGCTGGCCGCTTATCGGGGTACTGTGCGTCGTGCAGTTCATCGCCAGACCGCTGTGCATCGCCGTCTCG
ACCTGGCGATCCTCGCTGCATTGGCGCGAGCGGCTATTACTCAGCTGGATCGCACCGCGCGGCATCGTCGCCGCGGCCGT
CAGCGCCCTCTTTGCCCTGACGCTGCAGCGCAGCGGCTACCCCGATGCCGGGCGCCTGGTGACGGTGGTCTTCGCCATTA
TCATCGGTACCGTCATCCTGCAGAGCCTGACCAGCCGCCTCGTGGCCCGCCTGCTGCGCGTCCAACAGCGTAGGCCGCGC
GGCGTGCTGATCATCGGCGCCAATATCGTCGCCCGTATGCTGGCTCAGGCATTGATTAAGCTTGAGATCCCCGTCATCGT
CAGCGACAGCAGCTGGGAGTATTACCGCCAGGCACGCATGGAGGGGATCCCCGCCTATTACGGCCACGCCTATTCCGAGC
ATGCGGAAAACTACCTCAATCTCGGCGAGACAGCGCAGATGTTCGCCCTGTCGCCCAACCGCCACCAGAACGCTCTGGCC
ATCTACCACTTCGGCCATATCCTCGGCGATGAGAAGGTCTTCGCTCTCCGCTCCGGATCGCCGCTGAAAGGGCGCAGCGA
TGGTGCCGAAAGCGCGCGTTTCCGCCGCCATGAAAGCCTGTTCAGCCAAGAGGCCAGCTACGGGAAACTGAGTAGTCTGA
TCGCCAGGGGAGCCACCATCAAGGTCACCCGCCTGAATAAAAACTTCGGCTGGCCGGAGTATCTGGCGATACATCAGGGC
GTCATTCCGCTGTTTACCCTGTCGGAGAGCGGAAGGCTCCAGCCCGTACGCGCCGATAGCGCGCCAGCGGCCCCCTGCAC
CCTGATAGCACTGGTACAGAGCGATGGCGAGGCAGACCCCGCTCCCCGCCCCTGA

Upstream 100 bases:

>100_bases
AAGAACCACACACATATAGAAATGATGACTAAAAATAGACCCGCTAGAATATAAAGATACCCGTCTCCGTTAATCGTGCT
GTCTACAGAAAGGGATCGTT

Downstream 100 bases:

>100_bases
TGCCGCATGAGAACGCGGCAGCGCCGGGGTTAACCACGTTGACTCTGGCACCCTCAGCGACGCCGACGTCGGCGCGAGCA
GCATCCTGCCGGGCATTATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 603

Protein sequence:

>604_residues
MALSTPLMLVLIGLSALLAQWAAWSLRLPAILLLLLFGVILGPITHLVQPDRLFGELLFPLVSLSVAIILFEGALTLRLG
EIRGLGGVVRNLVSIGMLTTFAVIGLACWWLLRLPPELAALIGAVTVVTGPTVIAPLMRVVRPNASVNQVLRWEGIIIDP
IGAIFTLLVFEFIVLQQSAQSYGHLFWTLGSTVLVGLLVGLACGYLIGVSLRRAWVPGYLQNLAVLASMLAAFGLSNAIA
DESGLLTVTVIGILLANMRNVDTSDILAFKEELSVILISALFIILAARLDIAALWQMGWPLIGVLCVVQFIARPLCIAVS
TWRSSLHWRERLLLSWIAPRGIVAAAVSALFALTLQRSGYPDAGRLVTVVFAIIIGTVILQSLTSRLVARLLRVQQRRPR
GVLIIGANIVARMLAQALIKLEIPVIVSDSSWEYYRQARMEGIPAYYGHAYSEHAENYLNLGETAQMFALSPNRHQNALA
IYHFGHILGDEKVFALRSGSPLKGRSDGAESARFRRHESLFSQEASYGKLSSLIARGATIKVTRLNKNFGWPEYLAIHQG
VIPLFTLSESGRLQPVRADSAPAAPCTLIALVQSDGEADPAPRP

Sequences:

>Translated_604_residues
MALSTPLMLVLIGLSALLAQWAAWSLRLPAILLLLLFGVILGPITHLVQPDRLFGELLFPLVSLSVAIILFEGALTLRLG
EIRGLGGVVRNLVSIGMLTTFAVIGLACWWLLRLPPELAALIGAVTVVTGPTVIAPLMRVVRPNASVNQVLRWEGIIIDP
IGAIFTLLVFEFIVLQQSAQSYGHLFWTLGSTVLVGLLVGLACGYLIGVSLRRAWVPGYLQNLAVLASMLAAFGLSNAIA
DESGLLTVTVIGILLANMRNVDTSDILAFKEELSVILISALFIILAARLDIAALWQMGWPLIGVLCVVQFIARPLCIAVS
TWRSSLHWRERLLLSWIAPRGIVAAAVSALFALTLQRSGYPDAGRLVTVVFAIIIGTVILQSLTSRLVARLLRVQQRRPR
GVLIIGANIVARMLAQALIKLEIPVIVSDSSWEYYRQARMEGIPAYYGHAYSEHAENYLNLGETAQMFALSPNRHQNALA
IYHFGHILGDEKVFALRSGSPLKGRSDGAESARFRRHESLFSQEASYGKLSSLIARGATIKVTRLNKNFGWPEYLAIHQG
VIPLFTLSESGRLQPVRADSAPAAPCTLIALVQSDGEADPAPRP
>Mature_603_residues
ALSTPLMLVLIGLSALLAQWAAWSLRLPAILLLLLFGVILGPITHLVQPDRLFGELLFPLVSLSVAIILFEGALTLRLGE
IRGLGGVVRNLVSIGMLTTFAVIGLACWWLLRLPPELAALIGAVTVVTGPTVIAPLMRVVRPNASVNQVLRWEGIIIDPI
GAIFTLLVFEFIVLQQSAQSYGHLFWTLGSTVLVGLLVGLACGYLIGVSLRRAWVPGYLQNLAVLASMLAAFGLSNAIAD
ESGLLTVTVIGILLANMRNVDTSDILAFKEELSVILISALFIILAARLDIAALWQMGWPLIGVLCVVQFIARPLCIAVST
WRSSLHWRERLLLSWIAPRGIVAAAVSALFALTLQRSGYPDAGRLVTVVFAIIIGTVILQSLTSRLVARLLRVQQRRPRG
VLIIGANIVARMLAQALIKLEIPVIVSDSSWEYYRQARMEGIPAYYGHAYSEHAENYLNLGETAQMFALSPNRHQNALAI
YHFGHILGDEKVFALRSGSPLKGRSDGAESARFRRHESLFSQEASYGKLSSLIARGATIKVTRLNKNFGWPEYLAIHQGV
IPLFTLSESGRLQPVRADSAPAAPCTLIALVQSDGEADPAPRP

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=324, Percent_Identity=25, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 65587; Mature: 65455

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSTPLMLVLIGLSALLAQWAAWSLRLPAILLLLLFGVILGPITHLVQPDRLFGELLFP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LVSLSVAIILFEGALTLRLGEIRGLGGVVRNLVSIGMLTTFAVIGLACWWLLRLPPELAA
HHHHHHHHHHHHCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LIGAVTVVTGPTVIAPLMRVVRPNASVNQVLRWEGIIIDPIGAIFTLLVFEFIVLQQSAQ
HHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHH
SYGHLFWTLGSTVLVGLLVGLACGYLIGVSLRRAWVPGYLQNLAVLASMLAAFGLSNAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHC
DESGLLTVTVIGILLANMRNVDTSDILAFKEELSVILISALFIILAARLDIAALWQMGWP
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LIGVLCVVQFIARPLCIAVSTWRSSLHWRERLLLSWIAPRGIVAAAVSALFALTLQRSGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
PDAGRLVTVVFAIIIGTVILQSLTSRLVARLLRVQQRRPRGVLIIGANIVARMLAQALIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
LEIPVIVSDSSWEYYRQARMEGIPAYYGHAYSEHAENYLNLGETAQMFALSPNRHQNALA
HCCCEEEECCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCHHHHEEECCCCCCCCEE
IYHFGHILGDEKVFALRSGSPLKGRSDGAESARFRRHESLFSQEASYGKLSSLIARGATI
EEEHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEE
KVTRLNKNFGWPEYLAIHQGVIPLFTLSESGRLQPVRADSAPAAPCTLIALVQSDGEADP
EEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHEEEEECCCCCCCC
APRP
CCCC
>Mature Secondary Structure 
ALSTPLMLVLIGLSALLAQWAAWSLRLPAILLLLLFGVILGPITHLVQPDRLFGELLFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH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CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA