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The map label for this gene is luxS

Identifier: 238921092

GI number: 238921092

Start: 3104234

End: 3104749

Strand: Reverse

Name: luxS

Synonym: NT01EI_3227

Alternate gene names: 238921092

Gene position: 3104749-3104234 (Counterclockwise)

Preceding gene: 238921093

Following gene: 238921089

Centisome position: 81.44

GC content: 58.33

Gene sequence:

>516_bases
ATGCCGTTACTGGATAGCTTCACTGTCGACCATACCCGCATGGCCGCACCCGCCGTTCGCATAGCAAAAAATATGACCAC
CCCGCACGGCGATCAGATCACCGTATTCGATCTGCGCTTCTGCCGCCCTAACAATGCCATTCTGCCGGAGCGCGGTATTC
ATACCCTTGAGCACCTGTTTGCCGGCTTTATGCGCGACCATCTGAACGGCGACGGCGTTGAGATTATTGATATTTCACCG
ATGGGTTGCCGCACGGGCTTCTATATGAGCCTGATCGGCACGCCGGATGAAGCTCGGGTGGCCGCGGCCTGGAAGGCGGC
GATGGAGGACGTGCTGCGGGTCAGCGATCAGCGCAGCATTCCAGAGTTGAATGAGTTTCAGTGTGGCACCTACAGCATGC
ACTCGCTGGAAGAGGCGCACCAGATTGCCCGCCAGATCCTGGCATCCGGGATCGGTATCAACCATAATGATACGCTGGCG
CTCTCCGCCGAACAGCTGACCCATCTGCACCCCTAG

Upstream 100 bases:

>100_bases
GAAGACGCGCATGTGTGTCTTTCATATACTGAGAGTCGCAATATGGGAAAAGGTTTCCTAACAAAGGGAAAAAATATTTT
TTTATTGAGGAGGTGACGAA

Downstream 100 bases:

>100_bases
GGGGCGTATAAATAAATAGTGTTCGGCGTCGACGCTGAGCCAAAAGCGCATCATCGAGGCGCAGGGCGGAGGAGATCGTG
GGCCTATGCTCAAGCCCGGT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPLLDSFTVDHTRMAAPAVRIAKNMTTPHGDQITVFDLRFCRPNNAILPERGIHTLEHLFAGFMRDHLNGDGVEIIDISP
MGCRTGFYMSLIGTPDEARVAAAWKAAMEDVLRVSDQRSIPELNEFQCGTYSMHSLEEAHQIARQILASGIGINHNDTLA
LSAEQLTHLHP

Sequences:

>Translated_171_residues
MPLLDSFTVDHTRMAAPAVRIAKNMTTPHGDQITVFDLRFCRPNNAILPERGIHTLEHLFAGFMRDHLNGDGVEIIDISP
MGCRTGFYMSLIGTPDEARVAAAWKAAMEDVLRVSDQRSIPELNEFQCGTYSMHSLEEAHQIARQILASGIGINHNDTLA
LSAEQLTHLHP
>Mature_170_residues
PLLDSFTVDHTRMAAPAVRIAKNMTTPHGDQITVFDLRFCRPNNAILPERGIHTLEHLFAGFMRDHLNGDGVEIIDISPM
GCRTGFYMSLIGTPDEARVAAAWKAAMEDVLRVSDQRSIPELNEFQCGTYSMHSLEEAHQIARQILASGIGINHNDTLAL
SAEQLTHLHP

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=170, Percent_Identity=77.6470588235294, Blast_Score=284, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_EDWI9 (C5BGG6)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934607.1
- GeneID:   7961064
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3227
- OMA:   VRIAKTM
- ProtClustDB:   PRK02260
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 18972; Mature: 18841

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMAAPAVRIAKNMTTPHGDQITVFDLRFCRPNNAILPERGIHTLEHLF
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHH
AGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEARVAAAWKAAMEDVLRVSDQRSI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PELNEFQCGTYSMHSLEEAHQIARQILASGIGINHNDTLALSAEQLTHLHP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCC
>Mature Secondary Structure 
PLLDSFTVDHTRMAAPAVRIAKNMTTPHGDQITVFDLRFCRPNNAILPERGIHTLEHLF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHH
AGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEARVAAAWKAAMEDVLRVSDQRSI
HHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PELNEFQCGTYSMHSLEEAHQIARQILASGIGINHNDTLALSAEQLTHLHP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA