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The map label for this gene is alaS [H]

Identifier: 238920792

GI number: 238920792

Start: 2805108

End: 2805875

Strand: Reverse

Name: alaS [H]

Synonym: NT01EI_2911

Alternate gene names: 238920792

Gene position: 2805875-2805108 (Counterclockwise)

Preceding gene: 238920796

Following gene: 238920788

Centisome position: 73.6

GC content: 56.77

Gene sequence:

>768_bases
ATGAATATGGAATTTCACTATGACCGCGTCTACGCGCAGCCGGCGACGCAGCGGATATATAATCAGGAGTCTTACCTGAC
CACCCTGGAGGCCACGCTGCTGTACCTTGAAAACGACCTGGCGGTGTTCGACAGGACGATCTTCTACGCCGAGTCAGGGG
GGCAGGTTTGCGACGTCGGGTCAATCCGCGCCGTCGTGGGGGGGGCGCCTTGTCCGGTGGTTGATGTGCAGCATAAGCTG
GGACACAGGCTGTATATCAAGCGTGAGGGGGTTAACGTACCGTTGGTGGACGTAGAGACGCGGATCGTGCACCGCCTGGC
CTATGCACCGAATCTACAGCCCGGCGACCGCGTGATCATGCAGATCAACTGGTCACGACGCTATGCCATCATGCGTCACC
ATACGCTGGCGCACTTTCTGTTTTCTGCCTTTAGCCGCCACTTCAGCGCCAGTGCCAGCGTCAAGGGGTGTATCATCGAT
GCGCAAAAAGCGGTGTTCTCGCTGGATAAAAAGCTGAGCGATGATGATTTTTCCGCCATACAGTCCTATACCCGCGAAAT
GCTGGCGCAGGGTAGCCCGATGTGGATTGAACCGGCGCCGGAGACGGACACACTCTTTTACTGGAACTATGGTGAGACCA
TCATTCCATGTGGTGGCACCCATGTGCAGGCGCTGGCCGAAATCAGCGATGCGGCGATCTTTTTCCATAAAAAGAACACC
GGCCGCAAGCGCTGCCGGATCTCTATTGCGCTGCAGCCCTTGGTATAA

Upstream 100 bases:

>100_bases
GCCCGCAGGGTCGGATGATGGCAATCAGGGAGGCGATCACCGGTCGTGGCGTTAGCGTCAGAGGGACGGACGGGGATACC
CTGATCGGGATACATTGAGG

Downstream 100 bases:

>100_bases
CAGAAGCGCCGTGTGCGACTCAGTTGTGATGCTCCAGCAGACGCTGTAGCAGCACACCGTTCAGCATGGCGCGCTTGACC
AGTGCAAAGGCGCCGATGGC

Product: alanyl-tRNA synthetase

Products: NA

Alternate protein names: Alanine--tRNA ligase; AlaRS [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNMEFHYDRVYAQPATQRIYNQESYLTTLEATLLYLENDLAVFDRTIFYAESGGQVCDVGSIRAVVGGAPCPVVDVQHKL
GHRLYIKREGVNVPLVDVETRIVHRLAYAPNLQPGDRVIMQINWSRRYAIMRHHTLAHFLFSAFSRHFSASASVKGCIID
AQKAVFSLDKKLSDDDFSAIQSYTREMLAQGSPMWIEPAPETDTLFYWNYGETIIPCGGTHVQALAEISDAAIFFHKKNT
GRKRCRISIALQPLV

Sequences:

>Translated_255_residues
MNMEFHYDRVYAQPATQRIYNQESYLTTLEATLLYLENDLAVFDRTIFYAESGGQVCDVGSIRAVVGGAPCPVVDVQHKL
GHRLYIKREGVNVPLVDVETRIVHRLAYAPNLQPGDRVIMQINWSRRYAIMRHHTLAHFLFSAFSRHFSASASVKGCIID
AQKAVFSLDKKLSDDDFSAIQSYTREMLAQGSPMWIEPAPETDTLFYWNYGETIIPCGGTHVQALAEISDAAIFFHKKNT
GRKRCRISIALQPLV
>Mature_255_residues
MNMEFHYDRVYAQPATQRIYNQESYLTTLEATLLYLENDLAVFDRTIFYAESGGQVCDVGSIRAVVGGAPCPVVDVQHKL
GHRLYIKREGVNVPLVDVETRIVHRLAYAPNLQPGDRVIMQINWSRRYAIMRHHTLAHFLFSAFSRHFSASASVKGCIID
AQKAVFSLDKKLSDDDFSAIQSYTREMLAQGSPMWIEPAPETDTLFYWNYGETIIPCGGTHVQALAEISDAAIFFHKKNT
GRKRCRISIALQPLV

Specific function: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction:alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editin

COG id: COG0013

COG function: function code J; Alanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002318
- InterPro:   IPR018162
- InterPro:   IPR018165
- InterPro:   IPR018164
- InterPro:   IPR022429
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF01411 tRNA-synt_2c; PF07973 tRNA_SAD [H]

EC number: =6.1.1.7 [H]

Molecular weight: Translated: 28859; Mature: 28859

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMEFHYDRVYAQPATQRIYNQESYLTTLEATLLYLENDLAVFDRTIFYAESGGQVCDVG
CCCCEEEHEEECCHHHHHHHCCHHHHHHHHHEEEEEECCCEEEEEEEEEECCCCCEECCC
SIRAVVGGAPCPVVDVQHKLGHRLYIKREGVNVPLVDVETRIVHRLAYAPNLQPGDRVIM
CEEHEECCCCCCEEEHHHHCCCEEEEEECCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEE
QINWSRRYAIMRHHTLAHFLFSAFSRHFSASASVKGCIIDAQKAVFSLDKKLSDDDFSAI
EEECCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCCCHHHHH
QSYTREMLAQGSPMWIEPAPETDTLFYWNYGETIIPCGGTHVQALAEISDAAIFFHKKNT
HHHHHHHHHCCCCEEEECCCCCCEEEEEECCCEEEECCCHHHHHHHHHCCEEEEEEECCC
GRKRCRISIALQPLV
CCCEEEEEEEEECCC
>Mature Secondary Structure
MNMEFHYDRVYAQPATQRIYNQESYLTTLEATLLYLENDLAVFDRTIFYAESGGQVCDVG
CCCCEEEHEEECCHHHHHHHCCHHHHHHHHHEEEEEECCCEEEEEEEEEECCCCCEECCC
SIRAVVGGAPCPVVDVQHKLGHRLYIKREGVNVPLVDVETRIVHRLAYAPNLQPGDRVIM
CEEHEECCCCCCEEEHHHHCCCEEEEEECCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEE
QINWSRRYAIMRHHTLAHFLFSAFSRHFSASASVKGCIIDAQKAVFSLDKKLSDDDFSAI
EEECCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHCCCCCHHHHH
QSYTREMLAQGSPMWIEPAPETDTLFYWNYGETIIPCGGTHVQALAEISDAAIFFHKKNT
HHHHHHHHHCCCCEEEECCCCCCEEEEEECCCEEEECCCHHHHHHHHHCCEEEEEEECCC
GRKRCRISIALQPLV
CCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA