Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 238920774

GI number: 238920774

Start: 2784825

End: 2786465

Strand: Reverse

Name: pgm [H]

Synonym: NT01EI_2893

Alternate gene names: 238920774

Gene position: 2786465-2784825 (Counterclockwise)

Preceding gene: 238920775

Following gene: 238920768

Centisome position: 73.09

GC content: 63.13

Gene sequence:

>1641_bases
ATGGCAAATCACCCGCGTGCCGGGCAGCCCGCCCGACAGAGCGATTTGATCAATGTGGCTCAGCTGGCTGCACAGTATTA
CAGCCTGCGTCCGCAGGCGGATAATCCGTCCCACGCCGTGAAGTTCGGCACCTCAGGTCACCGCGGCAGCGCACAGCGCC
AAAGCTTCAACGAGGCGCACATTCTGGCGATCGCCCAGGCGATTGCCGAGGTGCGTAAGGCCAATGGCGTCGAGGGGCCC
TGCTTTGTCGGTAAAGATACCCATGCGCTCTCTGAGCCGGCCTTCATCAGCGTGCTGGAGGTGCTGAGTGCCAACGGTGT
TGCGGTGGTGGTGCAGGAGAGCAATGGCTTTACCCCGACGCCGGCGGTGTCACATGCCATTCTGACCCATAACCGTCGCG
GCGGCGCGCTGGCCGACGGTATTGTGATTACGCCCTCCCATAACCCGCCTGAAGATGGTGGCATCAAATACAACCCGACC
AACGGCGGCCCAGCGGATACCAATCTGACCAGCGTTATCGAGCAGCGTGCCAACCAGCTGCTGGCGCAGGAGCTGGCCGG
TGTGAAACGTCTGACGCTGGAGGCGGCCTGGCGCAGCGGCCATATCCATGCGCGCGACCTGGTGCAGCCCTACGTCGAGG
ATCTGCGCGATATCGTCGATATGCCAGCGATTCAGCGCGCCGGTCTGACGCTGGGCGTCGATCCGCTTGGCGGCTCCGGT
ATCGAATACTGGCAGCGCATCGGCGAGCATTACGGCCTGGATTTGACGCTGGTCAACGACCATATCGATCAGACCTTCCG
CTTTATGCATCTGGACCACGACGGCGTGATCCGCATGGACTGCTCTTCAGAAAGTGCCATGGCGGGGCTGCTGGCGCTGC
GCGATCGCTTCGACCTGGCCTTTGCCAATGACCCGGACTACGACCGTCACGGCATCGTAACGCCGACCGGGCTGATGAAC
CCGAACCACTATCTGGCCGTGGCCATTGACTACCTGTTCCGCCACCGTCCGCAGTGGGGGGCCGAGGTGGCTGTGGGTAA
GACGCTGGTCTCCAGCGCGATGATCGATCGGGTGGTTAAGGCGCTGGATCGCCGTCTGGTGGAAGTGCCGGTCGGTTTCA
AGTGGTTTGTCGACGGCCTGTTTGACGGCAGCCTCGGCTTTGGCGGTGAAGAGAGCGCCGGGGCATCGTTCCTACGCTTC
AACGGTACGCCGTGGTCCACCGATAAGGATGGCATCATCCTGTGCCTGCTGGCGGCCGAGATCACCGCCCAGACCGGTAA
GAATCCGCAGCAGCACTACGATGCGCTGGCAGCGCGCTTTGGCTCGCCGAGCTATAACCGCCTGCAGGCGCCGGCGACCC
ATGCCCAGAAGGCGGCGCTCTCCCGCCTCTCTCCGGAGATGGTGCAGGCAGACCGGCTGGCGGGTGATCCGATCACCGCG
CGCCTGACCCGCGCCCCGGGCAATGATGCGCCGATCGGCGGGCTGAAGATCATGACCGACAACGGCTGGTTTGCCGCGCG
TCCCTCCGGCACCGAGGAGGCCTACAAGATCTACTGTGAAAGCTTCTTGGGGGCGGAACATCGCCAGCGTATCGAGAAAG
AGGCGGTCGATATTGTGAGCGCCGTACTGACTAACGCTTAA

Upstream 100 bases:

>100_bases
TGGTCGAACACATCATGCTGGCGATGCAGTTCCCCATGGAGCTGATCGAGAAGGTTTGCGGCACCATTTGATAAATAACA
AGCGTTAGGGAGAAGCGCAG

Downstream 100 bases:

>100_bases
GCGCGTCATTATCCACCGCAACGCCGCGCACTGCGCGGCGTTTTTTGTCGATGGAAAACCCCCAGCTAGGCTGGGGGTTC
CGGAAAGCTCTCAGCTTTGA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MANHPRAGQPARQSDLINVAQLAAQYYSLRPQADNPSHAVKFGTSGHRGSAQRQSFNEAHILAIAQAIAEVRKANGVEGP
CFVGKDTHALSEPAFISVLEVLSANGVAVVVQESNGFTPTPAVSHAILTHNRRGGALADGIVITPSHNPPEDGGIKYNPT
NGGPADTNLTSVIEQRANQLLAQELAGVKRLTLEAAWRSGHIHARDLVQPYVEDLRDIVDMPAIQRAGLTLGVDPLGGSG
IEYWQRIGEHYGLDLTLVNDHIDQTFRFMHLDHDGVIRMDCSSESAMAGLLALRDRFDLAFANDPDYDRHGIVTPTGLMN
PNHYLAVAIDYLFRHRPQWGAEVAVGKTLVSSAMIDRVVKALDRRLVEVPVGFKWFVDGLFDGSLGFGGEESAGASFLRF
NGTPWSTDKDGIILCLLAAEITAQTGKNPQQHYDALAARFGSPSYNRLQAPATHAQKAALSRLSPEMVQADRLAGDPITA
RLTRAPGNDAPIGGLKIMTDNGWFAARPSGTEEAYKIYCESFLGAEHRQRIEKEAVDIVSAVLTNA

Sequences:

>Translated_546_residues
MANHPRAGQPARQSDLINVAQLAAQYYSLRPQADNPSHAVKFGTSGHRGSAQRQSFNEAHILAIAQAIAEVRKANGVEGP
CFVGKDTHALSEPAFISVLEVLSANGVAVVVQESNGFTPTPAVSHAILTHNRRGGALADGIVITPSHNPPEDGGIKYNPT
NGGPADTNLTSVIEQRANQLLAQELAGVKRLTLEAAWRSGHIHARDLVQPYVEDLRDIVDMPAIQRAGLTLGVDPLGGSG
IEYWQRIGEHYGLDLTLVNDHIDQTFRFMHLDHDGVIRMDCSSESAMAGLLALRDRFDLAFANDPDYDRHGIVTPTGLMN
PNHYLAVAIDYLFRHRPQWGAEVAVGKTLVSSAMIDRVVKALDRRLVEVPVGFKWFVDGLFDGSLGFGGEESAGASFLRF
NGTPWSTDKDGIILCLLAAEITAQTGKNPQQHYDALAARFGSPSYNRLQAPATHAQKAALSRLSPEMVQADRLAGDPITA
RLTRAPGNDAPIGGLKIMTDNGWFAARPSGTEEAYKIYCESFLGAEHRQRIEKEAVDIVSAVLTNA
>Mature_545_residues
ANHPRAGQPARQSDLINVAQLAAQYYSLRPQADNPSHAVKFGTSGHRGSAQRQSFNEAHILAIAQAIAEVRKANGVEGPC
FVGKDTHALSEPAFISVLEVLSANGVAVVVQESNGFTPTPAVSHAILTHNRRGGALADGIVITPSHNPPEDGGIKYNPTN
GGPADTNLTSVIEQRANQLLAQELAGVKRLTLEAAWRSGHIHARDLVQPYVEDLRDIVDMPAIQRAGLTLGVDPLGGSGI
EYWQRIGEHYGLDLTLVNDHIDQTFRFMHLDHDGVIRMDCSSESAMAGLLALRDRFDLAFANDPDYDRHGIVTPTGLMNP
NHYLAVAIDYLFRHRPQWGAEVAVGKTLVSSAMIDRVVKALDRRLVEVPVGFKWFVDGLFDGSLGFGGEESAGASFLRFN
GTPWSTDKDGIILCLLAAEITAQTGKNPQQHYDALAARFGSPSYNRLQAPATHAQKAALSRLSPEMVQADRLAGDPITAR
LTRAPGNDAPIGGLKIMTDNGWFAARPSGTEEAYKIYCESFLGAEHRQRIEKEAVDIVSAVLTNA

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=467, Percent_Identity=27.1948608137045, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI21361621, Length=457, Percent_Identity=27.7899343544858, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1786904, Length=546, Percent_Identity=82.051282051282, Blast_Score=923, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=549, Percent_Identity=26.5938069216758, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323752, Length=461, Percent_Identity=26.4642082429501, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322722, Length=539, Percent_Identity=27.4582560296846, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17864244, Length=439, Percent_Identity=26.1958997722096, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59001; Mature: 58870

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANHPRAGQPARQSDLINVAQLAAQYYSLRPQADNPSHAVKFGTSGHRGSAQRQSFNEAH
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHCCCHHH
ILAIAQAIAEVRKANGVEGPCFVGKDTHALSEPAFISVLEVLSANGVAVVVQESNGFTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCC
PAVSHAILTHNRRGGALADGIVITPSHNPPEDGGIKYNPTNGGPADTNLTSVIEQRANQL
HHHHHHHHHCCCCCCCEECCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
LAQELAGVKRLTLEAAWRSGHIHARDLVQPYVEDLRDIVDMPAIQRAGLTLGVDPLGGSG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCEEECCCCCCCH
IEYWQRIGEHYGLDLTLVNDHIDQTFRFMHLDHDGVIRMDCSSESAMAGLLALRDRFDLA
HHHHHHHHHHHCCEEEEECHHHHHHEEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCEE
FANDPDYDRHGIVTPTGLMNPNHYLAVAIDYLFRHRPQWGAEVAVGKTLVSSAMIDRVVK
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALDRRLVEVPVGFKWFVDGLFDGSLGFGGEESAGASFLRFNGTPWSTDKDGIILCLLAAE
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHH
ITAQTGKNPQQHYDALAARFGSPSYNRLQAPATHAQKAALSRLSPEMVQADRLAGDPITA
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEE
RLTRAPGNDAPIGGLKIMTDNGWFAARPSGTEEAYKIYCESFLGAEHRQRIEKEAVDIVS
EEEECCCCCCCCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AVLTNA
HHHHCC
>Mature Secondary Structure 
ANHPRAGQPARQSDLINVAQLAAQYYSLRPQADNPSHAVKFGTSGHRGSAQRQSFNEAH
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHCCCHHH
ILAIAQAIAEVRKANGVEGPCFVGKDTHALSEPAFISVLEVLSANGVAVVVQESNGFTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCC
PAVSHAILTHNRRGGALADGIVITPSHNPPEDGGIKYNPTNGGPADTNLTSVIEQRANQL
HHHHHHHHHCCCCCCCEECCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
LAQELAGVKRLTLEAAWRSGHIHARDLVQPYVEDLRDIVDMPAIQRAGLTLGVDPLGGSG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCEEECCCCCCCH
IEYWQRIGEHYGLDLTLVNDHIDQTFRFMHLDHDGVIRMDCSSESAMAGLLALRDRFDLA
HHHHHHHHHHHCCEEEEECHHHHHHEEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCEE
FANDPDYDRHGIVTPTGLMNPNHYLAVAIDYLFRHRPQWGAEVAVGKTLVSSAMIDRVVK
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALDRRLVEVPVGFKWFVDGLFDGSLGFGGEESAGASFLRFNGTPWSTDKDGIILCLLAAE
HHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHH
ITAQTGKNPQQHYDALAARFGSPSYNRLQAPATHAQKAALSRLSPEMVQADRLAGDPITA
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEE
RLTRAPGNDAPIGGLKIMTDNGWFAARPSGTEEAYKIYCESFLGAEHRQRIEKEAVDIVS
EEEECCCCCCCCCCEEEEECCCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
AVLTNA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]