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The map label for this gene is tolR [H]

Identifier: 238920740

GI number: 238920740

Start: 2747681

End: 2748103

Strand: Reverse

Name: tolR [H]

Synonym: NT01EI_2859

Alternate gene names: 238920740

Gene position: 2748103-2747681 (Counterclockwise)

Preceding gene: 238920741

Following gene: 238920739

Centisome position: 72.08

GC content: 55.79

Gene sequence:

>423_bases
ATGGCAAGATTAGGTGGGCGGCGCGATCTCAAGTCGGAAATCAACATCGTTCCGCTGCTCGACGTGCTGTTGGTGCTGGT
GCTGATCTTTATGGCGACGGCGCCGATTATTACGCAAAGCGTTGAGGTGGATTTGCCGGATGCGGCGGAGTCGAAAACCG
TCAGCACCAACGATCACCCGCCAGTGATCGTGGAGGTCTCCGGAATAGGGCAGTATGCTGTGGTGGTGGATCATAACCGC
ATGGAGCAGCTGCCGCCGGAGCAGGTGATCGCCGAGGCGCAGGCACAGCTTAAGGCTGATCCGAAAACGGTGTTTCTGAT
CGGGGGAGCCAAAGAGGTGCCGTATGATGAAATTATTAAGGCGCTCAATTTATTACATCAGGCCGGAGTCACCTCCGTGG
GACTGATGACGCAGCCGATTTAA

Upstream 100 bases:

>100_bases
GAATAAGCTGGAGCAGAACTATGAAAACTTCATGGAAGAGTTCATCGCCATTCTGCATCGCCAGGCCTTTGCCGCTGACG
GCAAGTAAGTTGAGGATAGC

Downstream 100 bases:

>100_bases
GGGATTCGCCGTCGCGTAGCGTAAGCAGACATGCAGCCTGTACAGGCTGCGTGTCTTTATTTTACGGTGCCAGCGCGGCG
AGTGGTGGCCTGGCCCGGCA

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MARLGGRRDLKSEINIVPLLDVLLVLVLIFMATAPIITQSVEVDLPDAAESKTVSTNDHPPVIVEVSGIGQYAVVVDHNR
MEQLPPEQVIAEAQAQLKADPKTVFLIGGAKEVPYDEIIKALNLLHQAGVTSVGLMTQPI

Sequences:

>Translated_140_residues
MARLGGRRDLKSEINIVPLLDVLLVLVLIFMATAPIITQSVEVDLPDAAESKTVSTNDHPPVIVEVSGIGQYAVVVDHNR
MEQLPPEQVIAEAQAQLKADPKTVFLIGGAKEVPYDEIIKALNLLHQAGVTSVGLMTQPI
>Mature_139_residues
ARLGGRRDLKSEINIVPLLDVLLVLVLIFMATAPIITQSVEVDLPDAAESKTVSTNDHPPVIVEVSGIGQYAVVVDHNRM
EQLPPEQVIAEAQAQLKADPKTVFLIGGAKEVPYDEIIKALNLLHQAGVTSVGLMTQPI

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). [C]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=132, Percent_Identity=83.3333333333333, Blast_Score=199, Evalue=4e-53,
Organism=Escherichia coli, GI1789380, Length=123, Percent_Identity=31.7073170731707, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15068; Mature: 14937

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLGGRRDLKSEINIVPLLDVLLVLVLIFMATAPIITQSVEVDLPDAAESKTVSTNDHP
CCCCCCCCCHHHHCCEECHHHHHHHHHHHHHHHCHHHHCCEEECCCCCCCCCCCCCCCCC
PVIVEVSGIGQYAVVVDHNRMEQLPPEQVIAEAQAQLKADPKTVFLIGGAKEVPYDEIIK
CEEEEECCCCEEEEEEECCHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH
ALNLLHQAGVTSVGLMTQPI
HHHHHHHCCCCCCCCEECCC
>Mature Secondary Structure 
ARLGGRRDLKSEINIVPLLDVLLVLVLIFMATAPIITQSVEVDLPDAAESKTVSTNDHP
CCCCCCCCHHHHCCEECHHHHHHHHHHHHHHHCHHHHCCEEECCCCCCCCCCCCCCCCC
PVIVEVSGIGQYAVVVDHNRMEQLPPEQVIAEAQAQLKADPKTVFLIGGAKEVPYDEIIK
CEEEEECCCCEEEEEEECCHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH
ALNLLHQAGVTSVGLMTQPI
HHHHHHHCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]