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The map label for this gene is pbpG [H]

Identifier: 238920707

GI number: 238920707

Start: 2711476

End: 2712405

Strand: Reverse

Name: pbpG [H]

Synonym: NT01EI_2820

Alternate gene names: 238920707

Gene position: 2712405-2711476 (Counterclockwise)

Preceding gene: 238920710

Following gene: 238920706

Centisome position: 71.15

GC content: 60.11

Gene sequence:

>930_bases
ATGGCTGTTAAACTCCGTTACTCCCTGTTAAGTCTGTTGATTCTGGGCGGCAGCATCAGCGCTCTTCCGGCTGCTCAGGC
CAGCGAGCCGCGTGCCGCTGCCGAGCTGCGCGCACCGCTGACGTTGGCATCGGGCAGCGCGATGGTGGTGGATCTGAATA
ATCATCAGGTTATCTACGCCAGCCACCCCGATATTCAGGTGCCGATCGCCTCGATAACCAAGCTGATGACGGCGATGGTG
ACGCTGGATGCGCACCCCAATCTGGATGAGGTTATCGCGGTCGACATTCACCGTACCAAAGAGTTGAAGGGCGTATTCTC
CCGGGTCCGGGTGGGCAGCGAGCTGACCCGCCGCCAAATGCTGCTGCTGGCGCTGATGTCGTCGGAGAACCGCGCTGCCG
CGACATTGGCGCACCACTACCCCGGCGGCTACGATGCGTTTATCCGGGCAATGAACGCCAAGGCCCGGGCGCTGGGGATG
ACCCGCACGCACTATGTAGAGCCGACCGGGCTGTCACCGGACAACGTATCGAGCGCCCGCGATCTGGTCAAACTGCTGCA
GGCGGCAAAGGGCTATCCGCTGATTGGCGAGCTGAGTACCACGGAGACCAGGAGTGTCACGTTTACCCATCCGACCTATA
CTGAAACCTTTAATAACACCAACCATCTGCTGCGCAACGACAAGTGGGATATCCAGATGACCAAGACCGGCTTTACCAAC
CAGGCGGGGCACTGCCTGGCGATGCGGACGGTGATCGGTGGTCGCCCGGTGGCGCTGGTGGTATTGGATGCCTTTGGCAA
GTATACCCATTTTGCCGATGCCAATCGGCTGCGCGAATGGATGCTGACGGGGAAGTCCGCTCCGGTTCCGGCGGTGGCGT
TAAGCTATAAACAGCAGAAAAACCTGGGCCAGCGTCTGGCCGAAAACTGA

Upstream 100 bases:

>100_bases
TTTGGCTCCGTACTCCTACCCGGGGACCGCTGTCGGTCATCGGTGCGGTGGGCTTCCCGGCGTATACCGGGTCCATTCCT
TGTGAGATTAATGAAGAAAC

Downstream 100 bases:

>100_bases
GTTCGCTCACCCCGTAGCGGGGCGCGCGATTCTCTGCTCCCGCGTGCGCCTGTTGGCGCACGGTTTTTTTATGGCATCAG
CCTATGATGGGGATCTCCCC

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAVKLRYSLLSLLILGGSISALPAAQASEPRAAAELRAPLTLASGSAMVVDLNNHQVIYASHPDIQVPIASITKLMTAMV
TLDAHPNLDEVIAVDIHRTKELKGVFSRVRVGSELTRRQMLLLALMSSENRAAATLAHHYPGGYDAFIRAMNAKARALGM
TRTHYVEPTGLSPDNVSSARDLVKLLQAAKGYPLIGELSTTETRSVTFTHPTYTETFNNTNHLLRNDKWDIQMTKTGFTN
QAGHCLAMRTVIGGRPVALVVLDAFGKYTHFADANRLREWMLTGKSAPVPAVALSYKQQKNLGQRLAEN

Sequences:

>Translated_309_residues
MAVKLRYSLLSLLILGGSISALPAAQASEPRAAAELRAPLTLASGSAMVVDLNNHQVIYASHPDIQVPIASITKLMTAMV
TLDAHPNLDEVIAVDIHRTKELKGVFSRVRVGSELTRRQMLLLALMSSENRAAATLAHHYPGGYDAFIRAMNAKARALGM
TRTHYVEPTGLSPDNVSSARDLVKLLQAAKGYPLIGELSTTETRSVTFTHPTYTETFNNTNHLLRNDKWDIQMTKTGFTN
QAGHCLAMRTVIGGRPVALVVLDAFGKYTHFADANRLREWMLTGKSAPVPAVALSYKQQKNLGQRLAEN
>Mature_308_residues
AVKLRYSLLSLLILGGSISALPAAQASEPRAAAELRAPLTLASGSAMVVDLNNHQVIYASHPDIQVPIASITKLMTAMVT
LDAHPNLDEVIAVDIHRTKELKGVFSRVRVGSELTRRQMLLLALMSSENRAAATLAHHYPGGYDAFIRAMNAKARALGMT
RTHYVEPTGLSPDNVSSARDLVKLLQAAKGYPLIGELSTTETRSVTFTHPTYTETFNNTNHLLRNDKWDIQMTKTGFTNQ
AGHCLAMRTVIGGRPVALVVLDAFGKYTHFADANRLREWMLTGKSAPVPAVALSYKQQKNLGQRLAEN

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=294, Percent_Identity=65.9863945578231, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1786851, Length=238, Percent_Identity=30.2521008403361, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082022, Length=253, Percent_Identity=28.4584980237154, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 33711; Mature: 33580

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKLRYSLLSLLILGGSISALPAAQASEPRAAAELRAPLTLASGSAMVVDLNNHQVIYA
CEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCEEEEECCCCEEEEE
SHPDIQVPIASITKLMTAMVTLDAHPNLDEVIAVDIHRTKELKGVFSRVRVGSELTRRQM
CCCCCEECHHHHHHHHHHHHEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHCHHHHHHHH
LLLALMSSENRAAATLAHHYPGGYDAFIRAMNAKARALGMTRTHYVEPTGLSPDNVSSAR
HHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCHHEEECCCCCCCCCHHHHH
DLVKLLQAAKGYPLIGELSTTETRSVTFTHPTYTETFNNTNHLLRNDKWDIQMTKTGFTN
HHHHHHHHHCCCCEEECCCCCCCCEEEEECCCHHHCCCCCHHHHCCCCCEEEEECCCCCC
QAGHCLAMRTVIGGRPVALVVLDAFGKYTHFADANRLREWMLTGKSAPVPAVALSYKQQK
CCCCEEEEEHHHCCCCEEEEEEEHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NLGQRLAEN
HHHHHHHCC
>Mature Secondary Structure 
AVKLRYSLLSLLILGGSISALPAAQASEPRAAAELRAPLTLASGSAMVVDLNNHQVIYA
EEEEHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCEEEECCCEEEEECCCCEEEEE
SHPDIQVPIASITKLMTAMVTLDAHPNLDEVIAVDIHRTKELKGVFSRVRVGSELTRRQM
CCCCCEECHHHHHHHHHHHHEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHCHHHHHHHH
LLLALMSSENRAAATLAHHYPGGYDAFIRAMNAKARALGMTRTHYVEPTGLSPDNVSSAR
HHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHHHCCCHHEEECCCCCCCCCHHHHH
DLVKLLQAAKGYPLIGELSTTETRSVTFTHPTYTETFNNTNHLLRNDKWDIQMTKTGFTN
HHHHHHHHHCCCCEEECCCCCCCCEEEEECCCHHHCCCCCHHHHCCCCCEEEEECCCCCC
QAGHCLAMRTVIGGRPVALVVLDAFGKYTHFADANRLREWMLTGKSAPVPAVALSYKQQK
CCCCEEEEEHHHCCCCEEEEEEEHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NLGQRLAEN
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]