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The map label for this gene is kbaZ [H]

Identifier: 238920704

GI number: 238920704

Start: 2707669

End: 2708949

Strand: Reverse

Name: kbaZ [H]

Synonym: NT01EI_2817

Alternate gene names: 238920704

Gene position: 2708949-2707669 (Counterclockwise)

Preceding gene: 238920705

Following gene: 238920703

Centisome position: 71.06

GC content: 62.84

Gene sequence:

>1281_bases
ATGCATCAGTTAGAACAGCTCGTACAGCGTCACAAGGCCGGTGAGCCGGTCGGTATCTATTCAGTCTGCTCCGCCCATCC
GCTGGTTATCGAAGCCGCGATGGAGCAGGCATTGCAGGACGATTCGCTCCTGCTGATCGAAGCCACCTCCAATCAGGTGG
ATCAGTTTGGCGGCTATACCGGGATGACCCCGGCCGACTTTCGCGACTATGTCTGTCGCCAGGCTGATTTACTGCAGTTC
CCGCTGGCCAACCTGATCCTGGGGGGCGACCACCTAGGCCCCAACCGTTGGCAGCACCTGCCAGCCGCCGAGGCGATGGC
CCATGCCGATACCCTGATCGCTGCCTACGTGGCCGCCGGTTTCCAAAAAATCCATCTCGATTGCAGCATGTCCTGTGCCG
ATGATCCGGTGCCGCTGAGCGACGCTACGGTCGCCGAGCGCGCCGCACGTCTGGCCGCCATCGCAGAGCGTACCGCGCGT
GAACAGTTTGGCCGCAGCCAGCTGGTGTACGTTATCGGCACCGAAGTGCCGGTACCGGGGGGCGCCAAAGAGCACATCGA
CACGCTGGAGGTCACCTCGCCGCAGGCGGCGCGCCAGACCATTGAATGTCACCGCGGGGCCTTTACCCGCGCCGGGATCG
CCGAGTGCTGGAACCGCGTCATCGGCCTGGTGGTACAGCCGGGCGTCGAGTTTGACCATACCGGTGTGATCGATTTTCGT
CCTCAGCAGGCCCAGGCGCTCAGTCAGGTGCTGGAGGATTATCCGCACCAGGTATTTGAGGCCCACTCCACCGACTACCA
GACTGATCGCGCCTACCGCGAGCTGGTGGACAACCACTTTGCGATCCTGAAAGTCGGCCCGGCGCTGACCTTCGCCCTGC
GCGAGGCGCTGTTCAGCCTGTGCCACATCGAAGAGGAGATGTATGGGCCGGAGCAGTGCTCCGGCCTGCGTCAGGCGATA
GAGACGGCGATGCTGGAAGCTCCGCAGAACTGGCAGAAATATTACAGCGGCAGCGAAGACCAGGTACGTTTTGCCCGTCG
CTACAGCTTCAGCGACCGTATTCGCTACTACTGGCCGACGCCGGCGGTGCAGGCGGCGCAGCAGACGCTGTTCCACAACC
TGACCCAGGCGCCGATCCCTTATCCGCTGCTCAGCCAGTATCTGCCGCGCGAGTTCACCGCCGTGCGCGAAGGCGAACTT
GCGCTGCACCCTGCGGCGCTGGTCAAGGCGCACATCAAACAGATTTTATCCGGCTACGCGCAGGCCTGCCTGCGTAACTA
A

Upstream 100 bases:

>100_bases
CGTCTGCGGGAAGCACACGTTGAAGTGATTATCGCTGAAAAAGAGAAGTGATGCGCTGACTCCACGGTAAACCGGCCCGT
GTTTATTGTGGAGTATTTTG

Downstream 100 bases:

>100_bases
TTAGGACGTGACTATGCAACACTATATGGGATATGACCTGGACGCGCTGCAGCGCCTCGGCGCGACATGGACGGCGAAAG
AAATTGAGCAACAGCCGGTA

Product: tagatose 6-phosphate kinase KbaZ

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MHQLEQLVQRHKAGEPVGIYSVCSAHPLVIEAAMEQALQDDSLLLIEATSNQVDQFGGYTGMTPADFRDYVCRQADLLQF
PLANLILGGDHLGPNRWQHLPAAEAMAHADTLIAAYVAAGFQKIHLDCSMSCADDPVPLSDATVAERAARLAAIAERTAR
EQFGRSQLVYVIGTEVPVPGGAKEHIDTLEVTSPQAARQTIECHRGAFTRAGIAECWNRVIGLVVQPGVEFDHTGVIDFR
PQQAQALSQVLEDYPHQVFEAHSTDYQTDRAYRELVDNHFAILKVGPALTFALREALFSLCHIEEEMYGPEQCSGLRQAI
ETAMLEAPQNWQKYYSGSEDQVRFARRYSFSDRIRYYWPTPAVQAAQQTLFHNLTQAPIPYPLLSQYLPREFTAVREGEL
ALHPAALVKAHIKQILSGYAQACLRN

Sequences:

>Translated_426_residues
MHQLEQLVQRHKAGEPVGIYSVCSAHPLVIEAAMEQALQDDSLLLIEATSNQVDQFGGYTGMTPADFRDYVCRQADLLQF
PLANLILGGDHLGPNRWQHLPAAEAMAHADTLIAAYVAAGFQKIHLDCSMSCADDPVPLSDATVAERAARLAAIAERTAR
EQFGRSQLVYVIGTEVPVPGGAKEHIDTLEVTSPQAARQTIECHRGAFTRAGIAECWNRVIGLVVQPGVEFDHTGVIDFR
PQQAQALSQVLEDYPHQVFEAHSTDYQTDRAYRELVDNHFAILKVGPALTFALREALFSLCHIEEEMYGPEQCSGLRQAI
ETAMLEAPQNWQKYYSGSEDQVRFARRYSFSDRIRYYWPTPAVQAAQQTLFHNLTQAPIPYPLLSQYLPREFTAVREGEL
ALHPAALVKAHIKQILSGYAQACLRN
>Mature_426_residues
MHQLEQLVQRHKAGEPVGIYSVCSAHPLVIEAAMEQALQDDSLLLIEATSNQVDQFGGYTGMTPADFRDYVCRQADLLQF
PLANLILGGDHLGPNRWQHLPAAEAMAHADTLIAAYVAAGFQKIHLDCSMSCADDPVPLSDATVAERAARLAAIAERTAR
EQFGRSQLVYVIGTEVPVPGGAKEHIDTLEVTSPQAARQTIECHRGAFTRAGIAECWNRVIGLVVQPGVEFDHTGVIDFR
PQQAQALSQVLEDYPHQVFEAHSTDYQTDRAYRELVDNHFAILKVGPALTFALREALFSLCHIEEEMYGPEQCSGLRQAI
ETAMLEAPQNWQKYYSGSEDQVRFARRYSFSDRIRYYWPTPAVQAAQQTLFHNLTQAPIPYPLLSQYLPREFTAVREGEL
ALHPAALVKAHIKQILSGYAQACLRN

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=423, Percent_Identity=62.6477541371158, Blast_Score=546, Evalue=1e-157,
Organism=Escherichia coli, GI1788411, Length=420, Percent_Identity=53.3333333333333, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 47395; Mature: 47395

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQLEQLVQRHKAGEPVGIYSVCSAHPLVIEAAMEQALQDDSLLLIEATSNQVDQFGGYT
CCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCC
GMTPADFRDYVCRQADLLQFPLANLILGGDHLGPNRWQHLPAAEAMAHADTLIAAYVAAG
CCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHC
FQKIHLDCSMSCADDPVPLSDATVAERAARLAAIAERTAREQFGRSQLVYVIGTEVPVPG
HHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
GAKEHIDTLEVTSPQAARQTIECHRGAFTRAGIAECWNRVIGLVVQPGVEFDHTGVIDFR
CCHHHCCHHCCCCCHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCEECC
PQQAQALSQVLEDYPHQVFEAHSTDYQTDRAYRELVDNHFAILKVGPALTFALREALFSL
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHH
CHIEEEMYGPEQCSGLRQAIETAMLEAPQNWQKYYSGSEDQVRFARRYSFSDRIRYYWPT
HHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCC
PAVQAAQQTLFHNLTQAPIPYPLLSQYLPREFTAVREGELALHPAALVKAHIKQILSGYA
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHCCCCCEECHHHHHHHHHHHHHHHHH
QACLRN
HHHHCC
>Mature Secondary Structure
MHQLEQLVQRHKAGEPVGIYSVCSAHPLVIEAAMEQALQDDSLLLIEATSNQVDQFGGYT
CCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCC
GMTPADFRDYVCRQADLLQFPLANLILGGDHLGPNRWQHLPAAEAMAHADTLIAAYVAAG
CCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHC
FQKIHLDCSMSCADDPVPLSDATVAERAARLAAIAERTAREQFGRSQLVYVIGTEVPVPG
HHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
GAKEHIDTLEVTSPQAARQTIECHRGAFTRAGIAECWNRVIGLVVQPGVEFDHTGVIDFR
CCHHHCCHHCCCCCHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHCCCCCCCCCCCCEECC
PQQAQALSQVLEDYPHQVFEAHSTDYQTDRAYRELVDNHFAILKVGPALTFALREALFSL
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHH
CHIEEEMYGPEQCSGLRQAIETAMLEAPQNWQKYYSGSEDQVRFARRYSFSDRIRYYWPT
HHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCC
PAVQAAQQTLFHNLTQAPIPYPLLSQYLPREFTAVREGELALHPAALVKAHIKQILSGYA
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHCCCCCEECHHHHHHHHHHHHHHHHH
QACLRN
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA