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The map label for this gene is agaR [H]

Identifier: 238920705

GI number: 238920705

Start: 2708999

End: 2709751

Strand: Reverse

Name: agaR [H]

Synonym: NT01EI_2818

Alternate gene names: 238920705

Gene position: 2709751-2708999 (Counterclockwise)

Preceding gene: 238920706

Following gene: 238920704

Centisome position: 71.08

GC content: 55.25

Gene sequence:

>753_bases
ATGGAAATCTTCAACGTCGTTACCTCCCAAGGGAAAGCGCGTGTTGAAGAGTTGGCCGCACGGTTTAACGTCTCAAGCGT
CACCATCCGCAGTGACCTGACTTTTCTGGAAGAAAACGGCTACATCGTGCGTTCGCATGGCGCGGCAATCCCCAATACCG
GGGTGATCGCCGAACTGAGCGTCCACGAGAAGCGCCACCGCAACAGCGGTGTGAAGTCCCAGATAGGTCTGGCTGCGGCC
AAGCTGATTAACAGCGGTGACGCGGTGATTCTGGATTCTGGTACGACGACCCGTGAGATCGCAGGGCACCTACGGGGCCT
CGAAAACGTGGTGGTCATGACTAACGGTCTGGATGTCGCCGTGGAGCTCGTCTCCTCACCGGGTATCGAAGTGGTGTGTA
CCGGTGGGGTGTTACGTAAGAGCGCAATGTCTTTTTCAGGCTCGCAGGCCGAAGCCTGCTTGAAAAACTTCTGTTTCGAC
AAGGTTTTTCTCGGGGTGGATGGATTCGATCTGCGAGCGGGTATCACCACGCACAATGAGCAGGAAGCGAGTCTTAACCG
CTTGATGTGCGAGATCTCCGATCAGGTGATCGCCGTTGCCGACTCGACCAAGTTCGGCAAGCGTGGCTACCACATGATTC
GGGATTTTACGGATATCGATATCCTGGTGACGGATTCCGGGGTGCCCGATGAATATGTCGAGCGTCTGCGGGAAGCACAC
GTTGAAGTGATTATCGCTGAAAAAGAGAAGTGA

Upstream 100 bases:

>100_bases
CAATCGTAATTTTATTAATCTTAGACCGAGGCCAGTTGAAGTTCGCTTTAACTGGTTTCGTAAGGGGACAAAAGTGAAAG
CGGCAGCAATCGAAAGGCGC

Downstream 100 bases:

>100_bases
TGCGCTGACTCCACGGTAAACCGGCCCGTGTTTATTGTGGAGTATTTTGATGCATCAGTTAGAACAGCTCGTACAGCGTC
ACAAGGCCGGTGAGCCGGTC

Product: glucitol operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MEIFNVVTSQGKARVEELAARFNVSSVTIRSDLTFLEENGYIVRSHGAAIPNTGVIAELSVHEKRHRNSGVKSQIGLAAA
KLINSGDAVILDSGTTTREIAGHLRGLENVVVMTNGLDVAVELVSSPGIEVVCTGGVLRKSAMSFSGSQAEACLKNFCFD
KVFLGVDGFDLRAGITTHNEQEASLNRLMCEISDQVIAVADSTKFGKRGYHMIRDFTDIDILVTDSGVPDEYVERLREAH
VEVIIAEKEK

Sequences:

>Translated_250_residues
MEIFNVVTSQGKARVEELAARFNVSSVTIRSDLTFLEENGYIVRSHGAAIPNTGVIAELSVHEKRHRNSGVKSQIGLAAA
KLINSGDAVILDSGTTTREIAGHLRGLENVVVMTNGLDVAVELVSSPGIEVVCTGGVLRKSAMSFSGSQAEACLKNFCFD
KVFLGVDGFDLRAGITTHNEQEASLNRLMCEISDQVIAVADSTKFGKRGYHMIRDFTDIDILVTDSGVPDEYVERLREAH
VEVIIAEKEK
>Mature_250_residues
MEIFNVVTSQGKARVEELAARFNVSSVTIRSDLTFLEENGYIVRSHGAAIPNTGVIAELSVHEKRHRNSGVKSQIGLAAA
KLINSGDAVILDSGTTTREIAGHLRGLENVVVMTNGLDVAVELVSSPGIEVVCTGGVLRKSAMSFSGSQAEACLKNFCFD
KVFLGVDGFDLRAGITTHNEQEASLNRLMCEISDQVIAVADSTKFGKRGYHMIRDFTDIDILVTDSGVPDEYVERLREAH
VEVIIAEKEK

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=246, Percent_Identity=46.3414634146341, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1789059, Length=244, Percent_Identity=36.0655737704918, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI226510968, Length=252, Percent_Identity=30.5555555555556, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788069, Length=244, Percent_Identity=26.2295081967213, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789829, Length=242, Percent_Identity=29.3388429752066, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787540, Length=227, Percent_Identity=29.0748898678414, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082344, Length=248, Percent_Identity=25.8064516129032, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790753, Length=232, Percent_Identity=28.0172413793103, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787063, Length=246, Percent_Identity=23.5772357723577, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=24.5059288537549, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789170, Length=225, Percent_Identity=23.5555555555556, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27081; Mature: 27081

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFNVVTSQGKARVEELAARFNVSSVTIRSDLTFLEENGYIVRSHGAAIPNTGVIAELS
CCHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCEEEECCCEEEEECCCCCCCCCEEEEEH
VHEKRHRNSGVKSQIGLAAAKLINSGDAVILDSGTTTREIAGHLRGLENVVVMTNGLDVA
HHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCHHEE
VELVSSPGIEVVCTGGVLRKSAMSFSGSQAEACLKNFCFDKVFLGVDGFDLRAGITTHNE
HHHHCCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCEEEECCCCCCC
QEASLNRLMCEISDQVIAVADSTKFGKRGYHMIRDFTDIDILVTDSGVPDEYVERLREAH
HHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCC
VEVIIAEKEK
EEEEEEECCC
>Mature Secondary Structure
MEIFNVVTSQGKARVEELAARFNVSSVTIRSDLTFLEENGYIVRSHGAAIPNTGVIAELS
CCHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCEEEECCCEEEEECCCCCCCCCEEEEEH
VHEKRHRNSGVKSQIGLAAAKLINSGDAVILDSGTTTREIAGHLRGLENVVVMTNGLDVA
HHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCHHEE
VELVSSPGIEVVCTGGVLRKSAMSFSGSQAEACLKNFCFDKVFLGVDGFDLRAGITTHNE
HHHHCCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCEEEECCCCCCC
QEASLNRLMCEISDQVIAVADSTKFGKRGYHMIRDFTDIDILVTDSGVPDEYVERLREAH
HHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCC
VEVIIAEKEK
EEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]