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The map label for this gene is manD [H]

Identifier: 238920698

GI number: 238920698

Start: 2702604

End: 2703758

Strand: Reverse

Name: manD [H]

Synonym: NT01EI_2811

Alternate gene names: 238920698

Gene position: 2703758-2702604 (Counterclockwise)

Preceding gene: 238920699

Following gene: 238920697

Centisome position: 70.92

GC content: 67.1

Gene sequence:

>1155_bases
ATGTTAACCGCCTACCTGGCCGACAGCGTATTTACCCCCCGGGGGATTGAACGGGACGTCGCCGTGCTGGTTGACGACGG
CGTGATCACCGGTATCGGTCAGCCGATACCGTCGGGCGCCCGGACTGTGCATCTGCCCGGTCGCAGCCTGTGGCCGGGGC
TTGTCGATATACACATTCACGGCCGCGCCGGTGCCGACGTGATGGATGCGACGCCGCAGGCGCTGCAAACCATCGCCGAT
GCCCTGCCGCAGACCGGTGTGGTGGCCTGGGTTGGTACCACGGTCAGTGCGCCGCAGCAGGATGTCTGCCGGGCGCTGCA
GCAGGTCGGGGCGTTTATCGCCGCCGGTCAAGCGCACGGTGCCCGCCTGTTGGGCAGCTTTCTGGAGGGGCCGCACTTTA
CTGCCCCCTTCAGGGGCTCACACCCGGAGGCGTTTCTGAGCGCACCCGAGGGCGCGGCGCTGGAAGCCCTGTGGCAGGCC
AGCGCGGGAACGCTGCTGCGTGCGGCGCTGGCGCCGGAGTCTGCGGCGGCGATGCAGGCCATTACCTGGTGGCGGACGCG
TGGCGTAAAGGTTGGCGTTGCCCATACCGCGGCCAGTTTTGCCCAGATCGAAGAGGCCCATGGGCTGGGTGCAGACTGCG
GTGTGCACCTGTACAACGGTATGTCTGGCCTGCACCACCGGGAACCGGGCTGCTGTGGTGCGGTGCTGTATCTGGATATG
CTGGCTGAGCTGATCGCCGATGGGATCCACGTTAACCCGGTGATGCTGAATCTGGCCTACCGGATGAAGGGCTACCGCCA
CATCGCGCTGATCACCGACTGCATGCGCGCCGGTGGGCTGGGCGAGGGGCGCTATCGCCTGGGTGCCCAGGAGATCACGG
TACGCCGTGGCGAGGCGCGTACCGACGATGGCTCGCTGGCGGGCAGTACCTGCAGTCTGGATCAGGCGGTGCGCAATATG
GTCACCCTGGCCGGTGTTCCGGTCTGGGAGGCGGTGCAGATGGCGTCGGCGGTGCCGGCAGCCTATCTCGGCCTACAGGA
TCGTCTGGGGGCGATCCGTCCCGGCGCAGCCGCCAGTTTTACGGCGGTGGATCCGGCCATGGCGGTGGCTGAGACTTACA
TTAACGGCGAGTGCGCCTATCGACGTCCGGCCTGA

Upstream 100 bases:

>100_bases
TCTGCAGGAGATTGGCGCCAGCAGCGTACAGAATATGCGTCAGACGCTGGAAGCCGCGATGGCCCCCGTCGAATGCGAAG
CGAGCGACGGACTGTAAACC

Downstream 100 bases:

>100_bases
GCGCCGACGGGTGGCGTCGCTTGCCCATACACCACAAGGCGCGGCCATGCCAGCCATGACCGCGGTAAACCGGAGACCCG
CGGGGGAGTCATCGCCAGCG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MLTAYLADSVFTPRGIERDVAVLVDDGVITGIGQPIPSGARTVHLPGRSLWPGLVDIHIHGRAGADVMDATPQALQTIAD
ALPQTGVVAWVGTTVSAPQQDVCRALQQVGAFIAAGQAHGARLLGSFLEGPHFTAPFRGSHPEAFLSAPEGAALEALWQA
SAGTLLRAALAPESAAAMQAITWWRTRGVKVGVAHTAASFAQIEEAHGLGADCGVHLYNGMSGLHHREPGCCGAVLYLDM
LAELIADGIHVNPVMLNLAYRMKGYRHIALITDCMRAGGLGEGRYRLGAQEITVRRGEARTDDGSLAGSTCSLDQAVRNM
VTLAGVPVWEAVQMASAVPAAYLGLQDRLGAIRPGAAASFTAVDPAMAVAETYINGECAYRRPA

Sequences:

>Translated_384_residues
MLTAYLADSVFTPRGIERDVAVLVDDGVITGIGQPIPSGARTVHLPGRSLWPGLVDIHIHGRAGADVMDATPQALQTIAD
ALPQTGVVAWVGTTVSAPQQDVCRALQQVGAFIAAGQAHGARLLGSFLEGPHFTAPFRGSHPEAFLSAPEGAALEALWQA
SAGTLLRAALAPESAAAMQAITWWRTRGVKVGVAHTAASFAQIEEAHGLGADCGVHLYNGMSGLHHREPGCCGAVLYLDM
LAELIADGIHVNPVMLNLAYRMKGYRHIALITDCMRAGGLGEGRYRLGAQEITVRRGEARTDDGSLAGSTCSLDQAVRNM
VTLAGVPVWEAVQMASAVPAAYLGLQDRLGAIRPGAAASFTAVDPAMAVAETYINGECAYRRPA
>Mature_384_residues
MLTAYLADSVFTPRGIERDVAVLVDDGVITGIGQPIPSGARTVHLPGRSLWPGLVDIHIHGRAGADVMDATPQALQTIAD
ALPQTGVVAWVGTTVSAPQQDVCRALQQVGAFIAAGQAHGARLLGSFLEGPHFTAPFRGSHPEAFLSAPEGAALEALWQA
SAGTLLRAALAPESAAAMQAITWWRTRGVKVGVAHTAASFAQIEEAHGLGADCGVHLYNGMSGLHHREPGCCGAVLYLDM
LAELIADGIHVNPVMLNLAYRMKGYRHIALITDCMRAGGLGEGRYRLGAQEITVRRGEARTDDGSLAGSTCSLDQAVRNM
VTLAGVPVWEAVQMASAVPAAYLGLQDRLGAIRPGAAASFTAVDPAMAVAETYINGECAYRRPA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=379, Percent_Identity=32.4538258575198, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI224922791, Length=374, Percent_Identity=32.620320855615, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1786892, Length=375, Percent_Identity=27.7333333333333, Blast_Score=158, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17553768, Length=351, Percent_Identity=29.6296296296296, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI19920392, Length=349, Percent_Identity=29.512893982808, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281361140, Length=362, Percent_Identity=29.2817679558011, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40152; Mature: 40152

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAYLADSVFTPRGIERDVAVLVDDGVITGIGQPIPSGARTVHLPGRSLWPGLVDIHIH
CEEHEECCCCCCCCCCCCCEEEEEECCEEECCCCCCCCCCEEEECCCCCCCCCEEEEEEE
GRAGADVMDATPQALQTIADALPQTGVVAWVGTTVSAPQQDVCRALQQVGAFIAAGQAHG
CCCCCCHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHH
ARLLGSFLEGPHFTAPFRGSHPEAFLSAPEGAALEALWQASAGTLLRAALAPESAAAMQA
HHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCHHHHHHH
ITWWRTRGVKVGVAHTAASFAQIEEAHGLGADCGVHLYNGMSGLHHREPGCCGAVLYLDM
HHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHH
LAELIADGIHVNPVMLNLAYRMKGYRHIALITDCMRAGGLGEGRYRLGAQEITVRRGEAR
HHHHHHCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCEECCHHHEEEECCCCC
TDDGSLAGSTCSLDQAVRNMVTLAGVPVWEAVQMASAVPAAYLGLQDRLGAIRPGAAASF
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHCHHHHCCCCCCCCCCCC
TAVDPAMAVAETYINGECAYRRPA
CCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLTAYLADSVFTPRGIERDVAVLVDDGVITGIGQPIPSGARTVHLPGRSLWPGLVDIHIH
CEEHEECCCCCCCCCCCCCEEEEEECCEEECCCCCCCCCCEEEECCCCCCCCCEEEEEEE
GRAGADVMDATPQALQTIADALPQTGVVAWVGTTVSAPQQDVCRALQQVGAFIAAGQAHG
CCCCCCHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHH
ARLLGSFLEGPHFTAPFRGSHPEAFLSAPEGAALEALWQASAGTLLRAALAPESAAAMQA
HHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHCHHHHHHHHHCCCHHHHHHH
ITWWRTRGVKVGVAHTAASFAQIEEAHGLGADCGVHLYNGMSGLHHREPGCCGAVLYLDM
HHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHH
LAELIADGIHVNPVMLNLAYRMKGYRHIALITDCMRAGGLGEGRYRLGAQEITVRRGEAR
HHHHHHCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCCEECCHHHEEEECCCCC
TDDGSLAGSTCSLDQAVRNMVTLAGVPVWEAVQMASAVPAAYLGLQDRLGAIRPGAAASF
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHCHHHHCCCCCCCCCCCC
TAVDPAMAVAETYINGECAYRRPA
CCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]