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The map label for this gene is yajL [H]

Identifier: 238920691

GI number: 238920691

Start: 2694971

End: 2695552

Strand: Reverse

Name: yajL [H]

Synonym: NT01EI_2804

Alternate gene names: 238920691

Gene position: 2695552-2694971 (Counterclockwise)

Preceding gene: 238920692

Following gene: 238920690

Centisome position: 70.71

GC content: 57.04

Gene sequence:

>582_bases
ATGACGAAACGGGTTGCCGTCCTGTTGGCACACGGATTTGAAGAGGGTGAGGCGGTGGTGTTTATCGACATCATGCGTCG
CCTGGATATTCAGGTGGAGATCCTCTCCTGCGAGGAGAGCCTGGCGCTGAACAGCTATTTTGAGACCCCTATCCGGGCCG
ATGCGCTGCTGGCCGATCGCCAAGAGACGCTTTATGACGCGGTGATGATGCCGGGTGGGCCACAGGGCACCGATCGCCTT
AACGCCAGCGCTATGGTCTTGGCTTTCTTGCGTCGTCATATCGCCGCCGATAAGTATATCTGCGCATTGTGCTCTTCCGG
CGCTAAGGTCTTAGCGGCGCATGGCTTGCTGGAAGGTCGGCGTTATAGTACCGGGGATAAGTTGGCCGAGCGCTTTGCCG
ATGGCGAATATGTCGATCGTGACGTGGTGGTCGATGGGCGTTTCATCTCCGCCAAGGGGTTGGGCGTCAGCTTTGAATTT
GCCTTTACGGTGGCGCGTCACCTCTTGGCCGACAATGTGGCTAAGGTCGATGCTCAGGCCAGCCATATCTATTTTCGTCG
CTGGCCACTGTCTGAAGAGTAA

Upstream 100 bases:

>100_bases
GCGTCACTATATGGAACCGGGTAAGGCCGCGATGCAGCAGGTGGTGGAGCAGAAAATCCGCATCTGCGGCAGCGCCGGGC
AGCTGTAAGGAGCACTGAGC

Downstream 100 bases:

>100_bases
TTAATTGCCGAAGCGTTTTTAGGGGTTACTTTGACTGCGACGGTATCACCGCAAGGTGATACCGTTTTTTTTATTATAAC
GCCATTCTTTCTTCTTACTT

Product: ThiJ/PfpI-family thiamine biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MTKRVAVLLAHGFEEGEAVVFIDIMRRLDIQVEILSCEESLALNSYFETPIRADALLADRQETLYDAVMMPGGPQGTDRL
NASAMVLAFLRRHIAADKYICALCSSGAKVLAAHGLLEGRRYSTGDKLAERFADGEYVDRDVVVDGRFISAKGLGVSFEF
AFTVARHLLADNVAKVDAQASHIYFRRWPLSEE

Sequences:

>Translated_193_residues
MTKRVAVLLAHGFEEGEAVVFIDIMRRLDIQVEILSCEESLALNSYFETPIRADALLADRQETLYDAVMMPGGPQGTDRL
NASAMVLAFLRRHIAADKYICALCSSGAKVLAAHGLLEGRRYSTGDKLAERFADGEYVDRDVVVDGRFISAKGLGVSFEF
AFTVARHLLADNVAKVDAQASHIYFRRWPLSEE
>Mature_192_residues
TKRVAVLLAHGFEEGEAVVFIDIMRRLDIQVEILSCEESLALNSYFETPIRADALLADRQETLYDAVMMPGGPQGTDRLN
ASAMVLAFLRRHIAADKYICALCSSGAKVLAAHGLLEGRRYSTGDKLAERFADGEYVDRDVVVDGRFISAKGLGVSFEFA
FTVARHLLADNVAKVDAQASHIYFRRWPLSEE

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=177, Percent_Identity=32.7683615819209, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI31543380, Length=177, Percent_Identity=32.7683615819209, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI87081736, Length=192, Percent_Identity=26.5625, Blast_Score=70, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17558714, Length=158, Percent_Identity=30.379746835443, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531319, Length=164, Percent_Identity=27.4390243902439, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571932, Length=170, Percent_Identity=31.1764705882353, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24653499, Length=191, Percent_Identity=29.8429319371728, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 21372; Mature: 21240

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRVAVLLAHGFEEGEAVVFIDIMRRLDIQVEILSCEESLALNSYFETPIRADALLADR
CCCCEEEEEECCCCCCCEEEEEEHHHHCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHH
QETLYDAVMMPGGPQGTDRLNASAMVLAFLRRHIAADKYICALCSSGAKVLAAHGLLEGR
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCC
RYSTGDKLAERFADGEYVDRDVVVDGRFISAKGLGVSFEFAFTVARHLLADNVAKVDAQA
CCCCHHHHHHHHCCCCCCCCEEEECCEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCC
SHIYFRRWPLSEE
CEEEEEECCCCCC
>Mature Secondary Structure 
TKRVAVLLAHGFEEGEAVVFIDIMRRLDIQVEILSCEESLALNSYFETPIRADALLADR
CCCEEEEEECCCCCCCEEEEEEHHHHCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHH
QETLYDAVMMPGGPQGTDRLNASAMVLAFLRRHIAADKYICALCSSGAKVLAAHGLLEGR
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCCC
RYSTGDKLAERFADGEYVDRDVVVDGRFISAKGLGVSFEFAFTVARHLLADNVAKVDAQA
CCCCHHHHHHHHCCCCCCCCEEEECCEEEEECCCCEEHHHHHHHHHHHHHHHHHHCCCCC
SHIYFRRWPLSEE
CEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]