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The map label for this gene is folX [H]

Identifier: 238920598

GI number: 238920598

Start: 2604095

End: 2604469

Strand: Direct

Name: folX [H]

Synonym: NT01EI_2710

Alternate gene names: 238920598

Gene position: 2604095-2604469 (Clockwise)

Preceding gene: 238920597

Following gene: 238920599

Centisome position: 68.31

GC content: 52.53

Gene sequence:

>375_bases
ATGAGTCCACATTTCCCAGATGCCATCATCAAAATTAAAAACCTGCGTCTGCGTACGTTTATCGGCATTAACGAGGAGGA
AATAGCCAACCGGCAGGATGTGGTGATCAATATTGCCATTCACTACCCGGCGCAACAGGCCCGCCACAGCGAAGAGATCG
CCGATGCGCTCAACTACCGCACCATCACCAAACGCATCATCGCCCACGTGGAGCAAAACCGTTTTGCCCTGCTGGAGAAG
TTGACTCAGGATCTGCTGGCGATCGCTTGTGAACATCCTTGGGTCACCTATGCTGAAGTAGAGGTCGATAAACTTTACGC
CCTACGCTATGCCGATTCGGTCTCCGTGACCATGCGCTATAGCCGGGGGGAATAA

Upstream 100 bases:

>100_bases
GGCACGTCCGGCCACCCAGCGTGCCTACCGGCTCGCCCAGGCCTGATCCCCGCAGGCGGCTGCCCCCGCCTGTCCGCTAC
GTTACCATTCAGGATCGCTT

Downstream 100 bases:

>100_bases
GCGGAGGGAACGGTGCGTCGGCGCGCGCCGTAAGGAGCAGCCTATGGAGATCTTGATTACCGGTGCTACCGGTCTTATCG
GTCAGGCGCTGTGCGCCCGG

Product: D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase

Products: L-Threo-7,8-Dihydroneopterin Triphosphate. [C]

Alternate protein names: Dihydroneopterin triphosphate 2'-epimerase [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MSPHFPDAIIKIKNLRLRTFIGINEEEIANRQDVVINIAIHYPAQQARHSEEIADALNYRTITKRIIAHVEQNRFALLEK
LTQDLLAIACEHPWVTYAEVEVDKLYALRYADSVSVTMRYSRGE

Sequences:

>Translated_124_residues
MSPHFPDAIIKIKNLRLRTFIGINEEEIANRQDVVINIAIHYPAQQARHSEEIADALNYRTITKRIIAHVEQNRFALLEK
LTQDLLAIACEHPWVTYAEVEVDKLYALRYADSVSVTMRYSRGE
>Mature_123_residues
SPHFPDAIIKIKNLRLRTFIGINEEEIANRQDVVINIAIHYPAQQARHSEEIADALNYRTITKRIIAHVEQNRFALLEKL
TQDLLAIACEHPWVTYAEVEVDKLYALRYADSVSVTMRYSRGE

Specific function: Catalyzes the epimerization of carbon 2' of the side chain of dihydroneopterin triphosphate (H2NTP) to form dihydromonapterin triphosphate (H2MTP) [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI1788641, Length=117, Percent_Identity=76.0683760683761, Blast_Score=184, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: 5.-.-.- [C]

Molecular weight: Translated: 14364; Mature: 14232

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPHFPDAIIKIKNLRLRTFIGINEEEIANRQDVVINIAIHYPAQQARHSEEIADALNYR
CCCCCCCHHEEEECEEEEEEECCCHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
TITKRIIAHVEQNRFALLEKLTQDLLAIACEHPWVTYAEVEVDKLYALRYADSVSVTMRY
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHEEHCCCCEEEEEEE
SRGE
CCCC
>Mature Secondary Structure 
SPHFPDAIIKIKNLRLRTFIGINEEEIANRQDVVINIAIHYPAQQARHSEEIADALNYR
CCCCCCHHEEEECEEEEEEECCCHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHH
TITKRIIAHVEQNRFALLEKLTQDLLAIACEHPWVTYAEVEVDKLYALRYADSVSVTMRY
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHEEHCCCCEEEEEEE
SRGE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Erythro-7,8-Dihydroneopterin Triphosphate [C]

Specific reaction: D-Erythro-7,8-Dihydroneopterin Triphosphate = L-Threo-7,8-Dihydroneopterin Triphosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]