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The map label for this gene is pphA [H]

Identifier: 238920591

GI number: 238920591

Start: 2598648

End: 2599562

Strand: Reverse

Name: pphA [H]

Synonym: NT01EI_2703

Alternate gene names: 238920591

Gene position: 2599562-2598648 (Counterclockwise)

Preceding gene: 238920593

Following gene: 238920590

Centisome position: 68.19

GC content: 36.94

Gene sequence:

>915_bases
ATGAATGCATTACCTATGCTGCACGGTGCTACCCCAGGAACCCGACGTACAGCATTGAAAACAATACTACAGGAAAAAAA
AGGACTTCGTATTATGGAGGCTCATAGTCCACTGTCTGCGCTATTAGTTGAAAAAGCTGAATATAAGAATGATTCATCAG
ATAAAATAGAATTTGATGGTTTTTGGTCAAGTTCGTTAACTGACTCCACATTGCGCTGTAAACCAGATATCGAGCTTATT
GATATTTCAAGTCGATTTTCGAGAATTTCAGATATTTTTGATGTAACAACTAAACCAATGATATTTGATGGTGATACTGG
CGGAAAAGTAGAACATTTGCCTTATCATATTGCTCAGGCAGAAAATCTTGGTATCTCTGCATTTATTATAGAAGATAAAA
CCGGGTTGAAGAAAAACTCGCTCTTCGGCAACGAAGTTTCGCAAACTCAGGCCTCGATCGAGGAGTTTTCTGAAAAAATA
GCTATTGCTAAACAAGCACAGATTACCCCAGAATTCATGTTGATTGCTCGGATAGAAAGTTTAATCCTTGAAGCAGGCAT
GGATGATGCTATCAACCGTGCATTGACTTATGTTGATTCTGGTGCAGATAGTATTATGATTCATAGCCGAAAAAAAGATG
CTGGCGAGATCCTAAAATTTGCAAAAATATTTAGAGCTCATTATAGGGATGTTCCTCTTGTATGTGTTCCAACAAGTTTC
AATGAAGTTCATTTTGATCATTTAATCGATGGCGGATTTAATATTGTTATATATGCCAATCATCTATTAAGAGCATCTTA
TCCAGCCATGCAATATGTTGCTGATCAGATACTTAAATATGGACGAACTCTCGAGATAGAAAATAAATGCTTACCCATTA
ATAAAGTCCTTGATCTAATCCCTGGGACACGTTGA

Upstream 100 bases:

>100_bases
TGTTTACATCAAGTGTGACTATTTTCGTTCCTGCCTCTTGTCTAATTAGAAAATATTATTGACATTATCAAAGGTAATAT
TTTAAAAAAGGAAAAATAAA

Downstream 100 bases:

>100_bases
GTTTCTTTTTTATATACTATAGATAATGTTGATCTTAGCGTTTTTTGCGAATTAACTTGGTGCGGATCCTACATTAATCC
TGCAAAGAAGATGGCGTTGA

Product: phosphoenolpyruvate phosphomutase

Products: NA

Alternate protein names: PPH [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNALPMLHGATPGTRRTALKTILQEKKGLRIMEAHSPLSALLVEKAEYKNDSSDKIEFDGFWSSSLTDSTLRCKPDIELI
DISSRFSRISDIFDVTTKPMIFDGDTGGKVEHLPYHIAQAENLGISAFIIEDKTGLKKNSLFGNEVSQTQASIEEFSEKI
AIAKQAQITPEFMLIARIESLILEAGMDDAINRALTYVDSGADSIMIHSRKKDAGEILKFAKIFRAHYRDVPLVCVPTSF
NEVHFDHLIDGGFNIVIYANHLLRASYPAMQYVADQILKYGRTLEIENKCLPINKVLDLIPGTR

Sequences:

>Translated_304_residues
MNALPMLHGATPGTRRTALKTILQEKKGLRIMEAHSPLSALLVEKAEYKNDSSDKIEFDGFWSSSLTDSTLRCKPDIELI
DISSRFSRISDIFDVTTKPMIFDGDTGGKVEHLPYHIAQAENLGISAFIIEDKTGLKKNSLFGNEVSQTQASIEEFSEKI
AIAKQAQITPEFMLIARIESLILEAGMDDAINRALTYVDSGADSIMIHSRKKDAGEILKFAKIFRAHYRDVPLVCVPTSF
NEVHFDHLIDGGFNIVIYANHLLRASYPAMQYVADQILKYGRTLEIENKCLPINKVLDLIPGTR
>Mature_304_residues
MNALPMLHGATPGTRRTALKTILQEKKGLRIMEAHSPLSALLVEKAEYKNDSSDKIEFDGFWSSSLTDSTLRCKPDIELI
DISSRFSRISDIFDVTTKPMIFDGDTGGKVEHLPYHIAQAENLGISAFIIEDKTGLKKNSLFGNEVSQTQASIEEFSEKI
AIAKQAQITPEFMLIARIESLILEAGMDDAINRALTYVDSGADSIMIHSRKKDAGEILKFAKIFRAHYRDVPLVCVPTSF
NEVHFDHLIDGGFNIVIYANHLLRASYPAMQYVADQILKYGRTLEIENKCLPINKVLDLIPGTR

Specific function: Hydrolyzes phosphonopyruvate. Not active towards phosphoenolpyruvate, glycerophosphate, phospho-L-serine or phosphoglycolic acid [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily. PEP mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786525, Length=195, Percent_Identity=27.1794871794872, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000918
- InterPro:   IPR012649
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =3.11.1.3 [H]

Molecular weight: Translated: 33946; Mature: 33946

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPMLHGATPGTRRTALKTILQEKKGLRIMEAHSPLSALLVEKAEYKNDSSDKIEFDG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEECC
FWSSSLTDSTLRCKPDIELIDISSRFSRISDIFDVTTKPMIFDGDTGGKVEHLPYHIAQA
EECCCCCCCEEEECCCCEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCEECCCEEHHHH
ENLGISAFIIEDKTGLKKNSLFGNEVSQTQASIEEFSEKIAIAKQAQITPEFMLIARIES
CCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LILEAGMDDAINRALTYVDSGADSIMIHSRKKDAGEILKFAKIFRAHYRDVPLVCVPTSF
HHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCC
NEVHFDHLIDGGFNIVIYANHLLRASYPAMQYVADQILKYGRTLEIENKCLPINKVLDLI
CHHHHHHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHC
PGTR
CCCC
>Mature Secondary Structure
MNALPMLHGATPGTRRTALKTILQEKKGLRIMEAHSPLSALLVEKAEYKNDSSDKIEFDG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEECC
FWSSSLTDSTLRCKPDIELIDISSRFSRISDIFDVTTKPMIFDGDTGGKVEHLPYHIAQA
EECCCCCCCEEEECCCCEEEECHHHHHHHHHHHHCCCCCEEEECCCCCCEECCCEEHHHH
ENLGISAFIIEDKTGLKKNSLFGNEVSQTQASIEEFSEKIAIAKQAQITPEFMLIARIES
CCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LILEAGMDDAINRALTYVDSGADSIMIHSRKKDAGEILKFAKIFRAHYRDVPLVCVPTSF
HHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCC
NEVHFDHLIDGGFNIVIYANHLLRASYPAMQYVADQILKYGRTLEIENKCLPINKVLDLI
CHHHHHHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHC
PGTR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12697754 [H]