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The map label for this gene is uxuA

Identifier: 238920468

GI number: 238920468

Start: 2472087

End: 2473277

Strand: Reverse

Name: uxuA

Synonym: NT01EI_2579

Alternate gene names: 238920468

Gene position: 2473277-2472087 (Counterclockwise)

Preceding gene: 238920470

Following gene: 238920467

Centisome position: 64.88

GC content: 59.28

Gene sequence:

>1191_bases
ATGGAACAAACTTGGCGTTGGTATGGCCCGAACGATCCGGTTTCCCTTGATGATGTCCGCCAGGCTGGGGCCACTGGCGT
AGTGACGGCGTTGCACCATATTCCAAACGGCGAAGTCTGGAGCGTGGAAGAGATTGAAAAGCGTAAAGCGCTGTTGGCTG
AGAAGGGGTTGACCTGGTCGGTGGTGGAGAGCGTTCCGGTTCATGAGGAGATTAAGACCCAGACCGGCAACTACCAGCGC
CATATCGACAACTACAAGCAGAGCCTGCGCAATCTGGCGGCCTGTGGGATCGATACCGTCTGCTATAACTTCATGCCGGT
GCTGGACTGGACGCGTACCGATCTGGAGTTCCAGCTGCCGGACGGCTCCAAGGCGCTGCGCTTCGATCAGATTGCCTTCG
CCGCCTTTGAGCTGCATATCCTGAAGCGCCCGGGCGCCGCAGAGGATTACAGCGCGGAAGAGCAGACACAGGCCAAGTCC
TACTTCGACGCGATGGGCGAGGCCGAGGTGACCAAGCTGACCGCCAATATCATTGCCGGCCTGCCGGGGGCGGAGGAGGG
CTATACCCTGGATCAGTTCCGCGCCCGTCTGGCGGAGTATGACGGTATTGATAAAGCGACGCTGCGTGAACACATGGCCC
ATTTCCTGCGTGAAATCGTACCGGTAGCGGAGGCCTGCGGCCTGCGTCTGGCGGTGCATCCTGATGATCCGCCGCGTCCG
ATTCTGGGTCTGCCGCGCATCGTCTCCACTGTAGAGGATATGCAGTGGCTGAAAGAGGTTGTCGACAGCGTATACAACGG
TTTTACCATGTGCACCGGGTCGTACGGCGTGCGTGCCGACAATGACCTGGTGGCGATGATCGAGCGTTTTGGCGATCGCA
TTCATTTTACCCACCTGCGCGCCACCTGTCGCGAAGCCAACCCGAAGAGCTTCCACGAAGGGGCTCATCTGCAGGGTGAT
GTCGATATGTTTGCGGTGGTCAAGGCGATCCTGACGGAAGAGTCCCGTCGTCAGCAGGCCGGCGACATGCGTCTGATTCC
GATGCGTCCGGACCACGGTCATCAGATGCTGGATGATCTGAAGAAGAAAACCAACCCGGGCTACTCCGCCATTGGCCGTC
TGAAAGGGCTGGCCGAGGTGCGCGGGGTCGAGCTGGCCATCAAGCGGGTCTATTTTCCGCAGATGAAGTAA

Upstream 100 bases:

>100_bases
ATTTGGTATGACAGATTATGCCGGTGAAGGCCGTGAAGCGTAAAATTTGTCTGACCCGTCACAGGAAGCCCCGTTAACAC
ACCGCAGAAGGTAACAGTAG

Downstream 100 bases:

>100_bases
AGTAACGGCGCGGGTGATGGCCTGAAAATAAAGGGGGGGACGCATGGGCGCCCCCCCTTTATTTTGCGCTAGGCGTCGGG
CTTAGAGCCGCTAACAAAAC

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIPNGEVWSVEEIEKRKALLAEKGLTWSVVESVPVHEEIKTQTGNYQR
HIDNYKQSLRNLAACGIDTVCYNFMPVLDWTRTDLEFQLPDGSKALRFDQIAFAAFELHILKRPGAAEDYSAEEQTQAKS
YFDAMGEAEVTKLTANIIAGLPGAEEGYTLDQFRARLAEYDGIDKATLREHMAHFLREIVPVAEACGLRLAVHPDDPPRP
ILGLPRIVSTVEDMQWLKEVVDSVYNGFTMCTGSYGVRADNDLVAMIERFGDRIHFTHLRATCREANPKSFHEGAHLQGD
VDMFAVVKAILTEESRRQQAGDMRLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIKRVYFPQMK

Sequences:

>Translated_396_residues
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIPNGEVWSVEEIEKRKALLAEKGLTWSVVESVPVHEEIKTQTGNYQR
HIDNYKQSLRNLAACGIDTVCYNFMPVLDWTRTDLEFQLPDGSKALRFDQIAFAAFELHILKRPGAAEDYSAEEQTQAKS
YFDAMGEAEVTKLTANIIAGLPGAEEGYTLDQFRARLAEYDGIDKATLREHMAHFLREIVPVAEACGLRLAVHPDDPPRP
ILGLPRIVSTVEDMQWLKEVVDSVYNGFTMCTGSYGVRADNDLVAMIERFGDRIHFTHLRATCREANPKSFHEGAHLQGD
VDMFAVVKAILTEESRRQQAGDMRLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIKRVYFPQMK
>Mature_396_residues
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIPNGEVWSVEEIEKRKALLAEKGLTWSVVESVPVHEEIKTQTGNYQR
HIDNYKQSLRNLAACGIDTVCYNFMPVLDWTRTDLEFQLPDGSKALRFDQIAFAAFELHILKRPGAAEDYSAEEQTQAKS
YFDAMGEAEVTKLTANIIAGLPGAEEGYTLDQFRARLAEYDGIDKATLREHMAHFLREIVPVAEACGLRLAVHPDDPPRP
ILGLPRIVSTVEDMQWLKEVVDSVYNGFTMCTGSYGVRADNDLVAMIERFGDRIHFTHLRATCREANPKSFHEGAHLQGD
VDMFAVVKAILTEESRRQQAGDMRLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIKRVYFPQMK

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family

Homologues:

Organism=Escherichia coli, GI1790778, Length=392, Percent_Identity=76.530612244898, Blast_Score=635, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXUA_EDWI9 (C5BG25)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933983.1
- ProteinModelPortal:   C5BG25
- GeneID:   7961767
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2579
- OMA:   VHEEIKT
- ProtClustDB:   PRK03906
- HAMAP:   MF_00106
- InterPro:   IPR004628
- InterPro:   IPR013022
- Gene3D:   G3DSA:3.20.20.150
- PIRSF:   PIRSF016049
- TIGRFAMs:   TIGR00695

Pfam domain/function: PF03786 UxuA; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.8

Molecular weight: Translated: 44590; Mature: 44590

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIPNGEVWSVEEIEKRKALLAEKGLTWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEECHHHHHHHHHHHHHCCCCEE
VVESVPVHEEIKTQTGNYQRHIDNYKQSLRNLAACGIDTVCYNFMPVLDWTRTDLEFQLP
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
DGSKALRFDQIAFAAFELHILKRPGAAEDYSAEEQTQAKSYFDAMGEAEVTKLTANIIAG
CCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHC
LPGAEEGYTLDQFRARLAEYDGIDKATLREHMAHFLREIVPVAEACGLRLAVHPDDPPRP
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
ILGLPRIVSTVEDMQWLKEVVDSVYNGFTMCTGSYGVRADNDLVAMIERFGDRIHFTHLR
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHCCCEEHHHHH
ATCREANPKSFHEGAHLQGDVDMFAVVKAILTEESRRQQAGDMRLIPMRPDHGHQMLDDL
HHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
KKKTNPGYSAIGRLKGLAEVRGVELAIKRVYFPQMK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIPNGEVWSVEEIEKRKALLAEKGLTWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEECHHHHHHHHHHHHHCCCCEE
VVESVPVHEEIKTQTGNYQRHIDNYKQSLRNLAACGIDTVCYNFMPVLDWTRTDLEFQLP
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
DGSKALRFDQIAFAAFELHILKRPGAAEDYSAEEQTQAKSYFDAMGEAEVTKLTANIIAG
CCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHC
LPGAEEGYTLDQFRARLAEYDGIDKATLREHMAHFLREIVPVAEACGLRLAVHPDDPPRP
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
ILGLPRIVSTVEDMQWLKEVVDSVYNGFTMCTGSYGVRADNDLVAMIERFGDRIHFTHLR
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHCCCEEHHHHH
ATCREANPKSFHEGAHLQGDVDMFAVVKAILTEESRRQQAGDMRLIPMRPDHGHQMLDDL
HHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHH
KKKTNPGYSAIGRLKGLAEVRGVELAIKRVYFPQMK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA