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The map label for this gene is dapA [H]

Identifier: 238920037

GI number: 238920037

Start: 2071268

End: 2072152

Strand: Direct

Name: dapA [H]

Synonym: NT01EI_2141

Alternate gene names: 238920037

Gene position: 2071268-2072152 (Clockwise)

Preceding gene: 238920036

Following gene: 238920041

Centisome position: 54.33

GC content: 51.07

Gene sequence:

>885_bases
ATGCTGACTCAGTTTTCTGGTATTTTTCCCTATCTGGTCTCACCGGTCGATAATCATACTGGCAGAGTATTGGAGCACCC
CCTGCGCAAGTTGGTTGAACATCTGATCGGCTGTGGCGTCCAGGGGCTCAGCCCCCTCGGTAGCACGGGGGAGTTTGCCT
ATCTATCCCTTGAGCAGCGGGAGGATATCGTGCACATTGTGCTTGATCAGGCGGCGGGAAGAGTCCCTGTGATTGCGGGT
GTGGCAGGGTTCTCCACCCATGAGCCCCTGAGGCAGACAGAGCGCTATAGCCGCCTGGGGGTTGATGGCATTGTCTTGAT
CATGCAGAGGATGTTTCCAGTCTCCCCTGCTGGACAAATGCACTTTTTTACCGATGTGGCGGAAAAATTTAGTGAAACCT
CAATGACGCTGTATACCAACCCCGGCCTGCTCGGTGCTGACATCCCATTGGAGGTTCTGGATGAGCTTAGTTATGTAAAT
AATATTGAATATATTAAGGATGCTTCAGTGAATACCGGGCGTATTCTAACGATGATTAATCGTTTCGGTTCACGCTTACG
TATATTTAGCGCCTCGGCACATATCCCACTGGTGGTGTTTCAGTTAGGGGGCGTGGGCTGGATGGCGGGCCCAGCCTGTG
TGATTCCCAAACAGTGTGTCGAGCTCTTTAATCTTTTTCAGGCTAATCAACTCGAACAGGCAATGGCACGGCAAAAACAG
CTATGGCGAATTAATGAGGTATTTACCCAGTATGCGCTAGCCGCCTGTATCAAGGCGGCATTAAACATTCAGGGATTTGC
CGTCGGGGATCCGATTTCACCGCAGCAACCACTTGGCACGGATGCCGTTAATGCGTTACATCAAGTGCTCGCCGAGATAC
AATAA

Upstream 100 bases:

>100_bases
ACCCACCCAAGGCTGCTAAAGTTTTATTCGAATCTCTGTATCAGGAAAATTTTTCACCTGAGCGGCCTTATGTCAATGCT
GTGATTTCCAAGGAGACATT

Downstream 100 bases:

>100_bases
AAATGACATTTGGCATCGTTATTTCGATGCCAAATTACTTACATCTTAGCGTGACCCATCATTTGAATTAATAATATCGC
TTAACTGCTCGGAGAGCTCG

Product: hypothetical protein

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLTQFSGIFPYLVSPVDNHTGRVLEHPLRKLVEHLIGCGVQGLSPLGSTGEFAYLSLEQREDIVHIVLDQAAGRVPVIAG
VAGFSTHEPLRQTERYSRLGVDGIVLIMQRMFPVSPAGQMHFFTDVAEKFSETSMTLYTNPGLLGADIPLEVLDELSYVN
NIEYIKDASVNTGRILTMINRFGSRLRIFSASAHIPLVVFQLGGVGWMAGPACVIPKQCVELFNLFQANQLEQAMARQKQ
LWRINEVFTQYALAACIKAALNIQGFAVGDPISPQQPLGTDAVNALHQVLAEIQ

Sequences:

>Translated_294_residues
MLTQFSGIFPYLVSPVDNHTGRVLEHPLRKLVEHLIGCGVQGLSPLGSTGEFAYLSLEQREDIVHIVLDQAAGRVPVIAG
VAGFSTHEPLRQTERYSRLGVDGIVLIMQRMFPVSPAGQMHFFTDVAEKFSETSMTLYTNPGLLGADIPLEVLDELSYVN
NIEYIKDASVNTGRILTMINRFGSRLRIFSASAHIPLVVFQLGGVGWMAGPACVIPKQCVELFNLFQANQLEQAMARQKQ
LWRINEVFTQYALAACIKAALNIQGFAVGDPISPQQPLGTDAVNALHQVLAEIQ
>Mature_294_residues
MLTQFSGIFPYLVSPVDNHTGRVLEHPLRKLVEHLIGCGVQGLSPLGSTGEFAYLSLEQREDIVHIVLDQAAGRVPVIAG
VAGFSTHEPLRQTERYSRLGVDGIVLIMQRMFPVSPAGQMHFFTDVAEKFSETSMTLYTNPGLLGADIPLEVLDELSYVN
NIEYIKDASVNTGRILTMINRFGSRLRIFSASAHIPLVVFQLGGVGWMAGPACVIPKQCVELFNLFQANQLEQAMARQKQ
LWRINEVFTQYALAACIKAALNIQGFAVGDPISPQQPLGTDAVNALHQVLAEIQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=289, Percent_Identity=25.6055363321799, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1788823, Length=247, Percent_Identity=27.9352226720648, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082415, Length=272, Percent_Identity=28.6764705882353, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786463, Length=248, Percent_Identity=28.6290322580645, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789620, Length=169, Percent_Identity=27.810650887574, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32273; Mature: 32273

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTQFSGIFPYLVSPVDNHTGRVLEHPLRKLVEHLIGCGVQGLSPLGSTGEFAYLSLEQR
CCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHH
EDIVHIVLDQAAGRVPVIAGVAGFSTHEPLRQTERYSRLGVDGIVLIMQRMFPVSPAGQM
HHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCH
HFFTDVAEKFSETSMTLYTNPGLLGADIPLEVLDELSYVNNIEYIKDASVNTGRILTMIN
HHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHH
RFGSRLRIFSASAHIPLVVFQLGGVGWMAGPACVIPKQCVELFNLFQANQLEQAMARQKQ
HHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LWRINEVFTQYALAACIKAALNIQGFAVGDPISPQQPLGTDAVNALHQVLAEIQ
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTQFSGIFPYLVSPVDNHTGRVLEHPLRKLVEHLIGCGVQGLSPLGSTGEFAYLSLEQR
CCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHH
EDIVHIVLDQAAGRVPVIAGVAGFSTHEPLRQTERYSRLGVDGIVLIMQRMFPVSPAGQM
HHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCH
HFFTDVAEKFSETSMTLYTNPGLLGADIPLEVLDELSYVNNIEYIKDASVNTGRILTMIN
HHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHH
RFGSRLRIFSASAHIPLVVFQLGGVGWMAGPACVIPKQCVELFNLFQANQLEQAMARQKQ
HHCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LWRINEVFTQYALAACIKAALNIQGFAVGDPISPQQPLGTDAVNALHQVLAEIQ
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA