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The map label for this gene is putA [H]

Identifier: 238920020

GI number: 238920020

Start: 2046615

End: 2050553

Strand: Direct

Name: putA [H]

Synonym: NT01EI_2124

Alternate gene names: 238920020

Gene position: 2046615-2050553 (Clockwise)

Preceding gene: 238920017

Following gene: 238920034

Centisome position: 53.68

GC content: 65.58

Gene sequence:

>3939_bases
ATGGCAACGACAACCATGGGCGTTAAGCTTGATGACGCCGCCCGCGAGCGCATCAAGGCAGCCGCCAGCCAGATTAACCG
TACACCGCACTGGCTAATCAAACAGGCCATCTTCAGCTATCTGGATCGCCTGGATCAGGGCGAAACGCTGCCGGAACTTC
CGCTCTCCTGTGTCGATCCCCTCCCTTTGGAAATAGCAGGGACACCACCACAGGAGGGACATACGCCCTTCCTGGCGTTC
GCCGAACAAATTCTGCCGCAGTCGGTGCTGCGGGCCAATATCACCGCAGCCTACCGGCGCGCGGAGAGCGATGCCGTTCC
TATGCTGCTCGAACAGGCCCGTCTGCCCTCCTCCCTGGCCAAGCAGGCGTATCAATTGGCCTACCGTCTGGCAGGGCAGC
TGCGCGGCCAGAAGAACGCCGGCGGACGGGCCGGAATGGTCCAGAGTCTGCTGCAGGAGTTCTCCCTCTCCTCCCAGGAG
GGCGTCGCACTGATGTGCCTGGCCGAGGCGCTGCTGCGCATTCCCGATAAGGCTACACGCGACGCGCTGATCCGTGACAA
GATCAGCGGCGGAGACTGGCAATCGCACCTCGGCCACAGCCCCTCACTGTTTGTCAACGCCGCCACCTGGGGGCTGCTGT
TCACCGGCAGGCTGGTCGCGACCCACAGCGAGGCCCACCTCTCCCACGCCCTGAGCCGGATCATCGGCAAGCGCGGTGAG
CCCCTGATCCGCAAAGGGGTAGATATGGCGATGCGTCTGATGGGGGAGCAGTTCGTCACCGGTGAAACCATCGACGAAGC
GCTGGCCAACGCGCACCGCTTAGAAGCCAAAGGCTTCAGCTACTCCTACGACATGCTGGGTGAGGCGGCGCTGACCAGCG
CCGACGCGCTGGCCTACCTGTGCTCCTACCAACAGGCGATCCATGCCATCGGTAAAGCCGCCAACGGGCGTGGCATCTAT
GAAGGACCGGGGATCTCGATCAAGCTCTCCGCCCTGCACCCGCGCTATAGCCGCGCCCAGTATGGGCGCGTGATGGAGGA
GCTGTATCCCACCCTTAAATCGCTCACCCTGCTGGCGCGCCAGTATGACATTGCGATCAACATCGACGCCGAAGAGGCTG
ACCGTCTGGAGCTCTCCCTCGATTTGTTGGAGAGGCTGTGTCATGAGCCCGAGCTGGCCGGCTGGAACGGCATCGGCTTT
GTGATCCAGGCCTACCAGAAGCGCTGTCCTGCGCTGATCGACTACCTGATCGATCTTGCCGCCCGCAGTCAGCGCCGTTT
GATGATCCGCCTGGTGAAAGGGGCCTACTGGGACAGCGAGATTAAGCGCGCCCAGGTCGACGGGCTGGAGGGCTACCCGG
TCTACACCCGCAAGGTCTATACCGACGTCTCCTACCTGGCCTGCGCCAGGAAGCTGTTGAGTGTGCCCAGCCTGATTTAC
CCTCAGTTCGCCACCCATAACGCCCATACGCTGGCGGCCATCTACCAGCTGGCCGGACAGAACTACTACCCGGGGCAGTA
TGAGTTCCAGTGTCTGCACGGCATGGGTGAGCCGCTATACCAACAGGTGGTCGGTAAGGTCGCCGATGGCAAGCTCCATC
GCCCCTGCCGTATCTATGCGCCGGTCGGCACCCATAAGACGCTGCTGGCCTACCTGGTGCGTCGTCTGCTGGAGAACGGC
GCCAACACCTCCTTCGTCAATCGCATCGCCGACACCAATCTGCCGCTGGAGGAGCTGGTCGCCGATCCGGTCGCCGCGGT
GGATCAGTTGACGGCGCAGGAGGGGCGCCCTGGACTCCCCCATCCGAAGATCCCACTCCCGCGCGATCTATATGCCCCGG
GACGTGCCAACGCCATCGGACTGGATCTGAGCAATGAGCAACGTCTGGCCTCCCTCTCCTGCGCCCTGTTAAACGGCGCC
AATCAGCGGCTGGTGGCGATACCGCTGCTGGAGCAGCCCTGTGCCGAAGGCGAGCTGCGCCCCCTGCCTAACCCCGCCGA
GCCGAATGACATCGTCGGCTATACCCGCGACGCCAGCGGGCAGGAGGTCGAACAGGCGTTGGCGAGCGCGCTGCGTAATG
CTCCCATCTGGTGTGCCACGCCGCCGCAGGAGCGCGCCGCCATCCTGGTACGGGCGGCCAGCCTGATGGAGCGCCAGATG
CCGACGCTGATGGGGATCCTGGTTCGTGAGGCGGGCAAGACCTTCGCCAACGCCATCGCCGAGGTGCGCGAAGCCGTCGA
CTTCCTGCGCTATTACGCCGGGCAGGTGCATGCCAGCTTCGACAACGAGACCCACCGCCCGCTGGGCTGCGTGGTCTGTA
TCAGCCCGTGGAACTTCCCGCTGGCCATCTTTACCGGTCAGATCGCCGCCGCGCTGGCCGCCGGCAACAGCGTACTGGCC
AAGCCCGCCGAACAGACACCGCTGATCGCCGCCCAGGCCATCGCCATCCTGCACGACGCCGGCGTCCCCCCCGGCGCCGT
GCAGCTGCTGCCGGGGCGCGGTGAAACCGTGGGCGCCCAGCTGGTCAATGACAGCCGGGTACGCGGCGTCATGTTTACCG
GATCGACAGAGGTCGCCAAGCGGTTACAACGCGCCGTCGCCGATCGGCTCGATGCACAGGGCCGGCCGACGCCGCTCATC
GCCGAAACCGGGGGACTCAACGCGATGATCGTCGACTCGTCGGCGCTGACCGAACAGGTTGTAACTGACGTTGTCACATC
CGCCTTCGACAGCGCCGGGCAACGCTGCTCCGCCCTGCGCCTCCTCTGTCTGCAGGAGGAGATCGCTGACCATACCCTGA
CCATGCTGCGCGGCGCCATGGCCGAATACCGCATCGGCAACCCGGAGCGACTGGGCTGCGACATTGGCCCGCTGATCGAC
ACCGAGGCCAAGAGCAGCATCGAGCAGCATATCCTCGCCATGCGGGCCAAGGGACACCCGGTATTCCAGGCGGCACACAG
CCAGGAGGAGGAGGCCCAGTGCGACGCGCGGGGTAACTTCGTTCCACCCACCCTGATCGAACTGGACAGCCTCAACGAAT
TACAAGAGGAGATCTTTGGTCCGGTGCTGCACGTGGTACGCTACCGCCGCGAGCAGCTGGATACGCTGCTGGCCCAAATC
AACGCCTCGGGCTACGGCCTGACCCTCGGAGTACATTCGCGCATCGACGAAACCATCGCCCACATCGCCCACAGCGCCCA
CGTCGGCAATATCTACGTTAACCGCAATATCGTCGGGGCCGTCGTCGGCGTACAGCCCTTCGGTGGCGAGGGACTCTCCG
GTACCGGGCCGAAGGCCGGCGGCCCGCTATACCTCTACCGCCTGCTGGCCCGCAGTCCGGAAAATACCCTGACGCTCGGC
ACCGACGCCTCCCCGCACCAGCCGAACAACGCCACGCCGCCGCTGCAGGCCCTGAACGACTGGGCCGCCGATCGCCCGGC
GCTCCAGATCCTGTGCCAGCACTACGCCAACCAGTGTCCCGCCGCCGTCCCGCGCCCGCTGGGCGGACCGACAGGCGAAC
GCAACACCCTGCTCTTTGTCCCGCGCGAACGGGTACTGTGCGCGGCGGGCAACGAGGACGACGCGCTGATCCAGCTGGCG
GCGGTCATGGCGGTCGGCTGTCACGTCCTGTGGCCGGACACGCCACTGCACCGCGCGCTGCACCGGGATCTTCCATCGGC
GGTCGCAGCGTGCATTACGCTGAGTCCGCCGGAGAGCCTGATGGCGCAAGAGTTCGACGCCGCGATCTACCACGGCGACA
GCGATCGGCTGCGCCTCCTCAGCGGGCAGATTGCCGCCCGCAGCGGCGCCATCGTCCCGCTGCAGGGCCTGGCGCCCGGC
GACACGCAACTGCGTCTGGAACTGTTGGTCCACGAGCGCGCGCTGAGCGTGAATACCGCGGCGGCAGGCGGCAACGCCAG
CCTGATGACCCTGAGCTAA

Upstream 100 bases:

>100_bases
GCCCAGCGCGGCGGCCTACCCAAGGCGCAGCAGCGCGGCTATGCTATTCCAGACTGCTGCCTCCGCCGCGCGACAGAGAG
AGCCAAAAGGAGTAAATGCG

Downstream 100 bases:

>100_bases
CCCCGCCTCGCGCCCCTTCGTGGGGCGCGCCTTCCCCGGCTATTCACGGCTGGCATCCCAACCCCGGCCGCAAAAAAATA
CCGCCCACCGGATGGTGAGC

Product: bifunctional protein PutA

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1312; Mature: 1311

Protein sequence:

>1312_residues
MATTTMGVKLDDAARERIKAAASQINRTPHWLIKQAIFSYLDRLDQGETLPELPLSCVDPLPLEIAGTPPQEGHTPFLAF
AEQILPQSVLRANITAAYRRAESDAVPMLLEQARLPSSLAKQAYQLAYRLAGQLRGQKNAGGRAGMVQSLLQEFSLSSQE
GVALMCLAEALLRIPDKATRDALIRDKISGGDWQSHLGHSPSLFVNAATWGLLFTGRLVATHSEAHLSHALSRIIGKRGE
PLIRKGVDMAMRLMGEQFVTGETIDEALANAHRLEAKGFSYSYDMLGEAALTSADALAYLCSYQQAIHAIGKAANGRGIY
EGPGISIKLSALHPRYSRAQYGRVMEELYPTLKSLTLLARQYDIAINIDAEEADRLELSLDLLERLCHEPELAGWNGIGF
VIQAYQKRCPALIDYLIDLAARSQRRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLSVPSLIY
PQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYQQVVGKVADGKLHRPCRIYAPVGTHKTLLAYLVRRLLENG
ANTSFVNRIADTNLPLEELVADPVAAVDQLTAQEGRPGLPHPKIPLPRDLYAPGRANAIGLDLSNEQRLASLSCALLNGA
NQRLVAIPLLEQPCAEGELRPLPNPAEPNDIVGYTRDASGQEVEQALASALRNAPIWCATPPQERAAILVRAASLMERQM
PTLMGILVREAGKTFANAIAEVREAVDFLRYYAGQVHASFDNETHRPLGCVVCISPWNFPLAIFTGQIAAALAAGNSVLA
KPAEQTPLIAAQAIAILHDAGVPPGAVQLLPGRGETVGAQLVNDSRVRGVMFTGSTEVAKRLQRAVADRLDAQGRPTPLI
AETGGLNAMIVDSSALTEQVVTDVVTSAFDSAGQRCSALRLLCLQEEIADHTLTMLRGAMAEYRIGNPERLGCDIGPLID
TEAKSSIEQHILAMRAKGHPVFQAAHSQEEEAQCDARGNFVPPTLIELDSLNELQEEIFGPVLHVVRYRREQLDTLLAQI
NASGYGLTLGVHSRIDETIAHIAHSAHVGNIYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLARSPENTLTLG
TDASPHQPNNATPPLQALNDWAADRPALQILCQHYANQCPAAVPRPLGGPTGERNTLLFVPRERVLCAAGNEDDALIQLA
AVMAVGCHVLWPDTPLHRALHRDLPSAVAACITLSPPESLMAQEFDAAIYHGDSDRLRLLSGQIAARSGAIVPLQGLAPG
DTQLRLELLVHERALSVNTAAAGGNASLMTLS

Sequences:

>Translated_1312_residues
MATTTMGVKLDDAARERIKAAASQINRTPHWLIKQAIFSYLDRLDQGETLPELPLSCVDPLPLEIAGTPPQEGHTPFLAF
AEQILPQSVLRANITAAYRRAESDAVPMLLEQARLPSSLAKQAYQLAYRLAGQLRGQKNAGGRAGMVQSLLQEFSLSSQE
GVALMCLAEALLRIPDKATRDALIRDKISGGDWQSHLGHSPSLFVNAATWGLLFTGRLVATHSEAHLSHALSRIIGKRGE
PLIRKGVDMAMRLMGEQFVTGETIDEALANAHRLEAKGFSYSYDMLGEAALTSADALAYLCSYQQAIHAIGKAANGRGIY
EGPGISIKLSALHPRYSRAQYGRVMEELYPTLKSLTLLARQYDIAINIDAEEADRLELSLDLLERLCHEPELAGWNGIGF
VIQAYQKRCPALIDYLIDLAARSQRRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLSVPSLIY
PQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYQQVVGKVADGKLHRPCRIYAPVGTHKTLLAYLVRRLLENG
ANTSFVNRIADTNLPLEELVADPVAAVDQLTAQEGRPGLPHPKIPLPRDLYAPGRANAIGLDLSNEQRLASLSCALLNGA
NQRLVAIPLLEQPCAEGELRPLPNPAEPNDIVGYTRDASGQEVEQALASALRNAPIWCATPPQERAAILVRAASLMERQM
PTLMGILVREAGKTFANAIAEVREAVDFLRYYAGQVHASFDNETHRPLGCVVCISPWNFPLAIFTGQIAAALAAGNSVLA
KPAEQTPLIAAQAIAILHDAGVPPGAVQLLPGRGETVGAQLVNDSRVRGVMFTGSTEVAKRLQRAVADRLDAQGRPTPLI
AETGGLNAMIVDSSALTEQVVTDVVTSAFDSAGQRCSALRLLCLQEEIADHTLTMLRGAMAEYRIGNPERLGCDIGPLID
TEAKSSIEQHILAMRAKGHPVFQAAHSQEEEAQCDARGNFVPPTLIELDSLNELQEEIFGPVLHVVRYRREQLDTLLAQI
NASGYGLTLGVHSRIDETIAHIAHSAHVGNIYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLARSPENTLTLG
TDASPHQPNNATPPLQALNDWAADRPALQILCQHYANQCPAAVPRPLGGPTGERNTLLFVPRERVLCAAGNEDDALIQLA
AVMAVGCHVLWPDTPLHRALHRDLPSAVAACITLSPPESLMAQEFDAAIYHGDSDRLRLLSGQIAARSGAIVPLQGLAPG
DTQLRLELLVHERALSVNTAAAGGNASLMTLS
>Mature_1311_residues
ATTTMGVKLDDAARERIKAAASQINRTPHWLIKQAIFSYLDRLDQGETLPELPLSCVDPLPLEIAGTPPQEGHTPFLAFA
EQILPQSVLRANITAAYRRAESDAVPMLLEQARLPSSLAKQAYQLAYRLAGQLRGQKNAGGRAGMVQSLLQEFSLSSQEG
VALMCLAEALLRIPDKATRDALIRDKISGGDWQSHLGHSPSLFVNAATWGLLFTGRLVATHSEAHLSHALSRIIGKRGEP
LIRKGVDMAMRLMGEQFVTGETIDEALANAHRLEAKGFSYSYDMLGEAALTSADALAYLCSYQQAIHAIGKAANGRGIYE
GPGISIKLSALHPRYSRAQYGRVMEELYPTLKSLTLLARQYDIAINIDAEEADRLELSLDLLERLCHEPELAGWNGIGFV
IQAYQKRCPALIDYLIDLAARSQRRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLSVPSLIYP
QFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYQQVVGKVADGKLHRPCRIYAPVGTHKTLLAYLVRRLLENGA
NTSFVNRIADTNLPLEELVADPVAAVDQLTAQEGRPGLPHPKIPLPRDLYAPGRANAIGLDLSNEQRLASLSCALLNGAN
QRLVAIPLLEQPCAEGELRPLPNPAEPNDIVGYTRDASGQEVEQALASALRNAPIWCATPPQERAAILVRAASLMERQMP
TLMGILVREAGKTFANAIAEVREAVDFLRYYAGQVHASFDNETHRPLGCVVCISPWNFPLAIFTGQIAAALAAGNSVLAK
PAEQTPLIAAQAIAILHDAGVPPGAVQLLPGRGETVGAQLVNDSRVRGVMFTGSTEVAKRLQRAVADRLDAQGRPTPLIA
ETGGLNAMIVDSSALTEQVVTDVVTSAFDSAGQRCSALRLLCLQEEIADHTLTMLRGAMAEYRIGNPERLGCDIGPLIDT
EAKSSIEQHILAMRAKGHPVFQAAHSQEEEAQCDARGNFVPPTLIELDSLNELQEEIFGPVLHVVRYRREQLDTLLAQIN
ASGYGLTLGVHSRIDETIAHIAHSAHVGNIYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLARSPENTLTLGT
DASPHQPNNATPPLQALNDWAADRPALQILCQHYANQCPAAVPRPLGGPTGERNTLLFVPRERVLCAAGNEDDALIQLAA
VMAVGCHVLWPDTPLHRALHRDLPSAVAACITLSPPESLMAQEFDAAIYHGDSDRLRLLSGQIAARSGAIVPLQGLAPGD
TQLRLELLVHERALSVNTAAAGGNASLMTLS

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=462, Percent_Identity=30.952380952381, Blast_Score=190, Evalue=6e-48,
Organism=Homo sapiens, GI25777736, Length=447, Percent_Identity=31.3199105145414, Blast_Score=181, Evalue=6e-45,
Organism=Homo sapiens, GI25777734, Length=447, Percent_Identity=31.3199105145414, Blast_Score=181, Evalue=6e-45,
Organism=Homo sapiens, GI238859541, Length=450, Percent_Identity=31.1111111111111, Blast_Score=180, Evalue=9e-45,
Organism=Homo sapiens, GI25777724, Length=471, Percent_Identity=28.8747346072187, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777730, Length=458, Percent_Identity=29.9126637554585, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI153266822, Length=432, Percent_Identity=29.3981481481481, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777732, Length=477, Percent_Identity=27.8825995807128, Blast_Score=170, Evalue=9e-42,
Organism=Homo sapiens, GI25777728, Length=416, Percent_Identity=29.8076923076923, Blast_Score=170, Evalue=1e-41,
Organism=Homo sapiens, GI21614513, Length=423, Percent_Identity=29.0780141843972, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI12007648, Length=447, Percent_Identity=28.8590604026846, Blast_Score=160, Evalue=9e-39,
Organism=Homo sapiens, GI4507229, Length=430, Percent_Identity=29.3023255813954, Blast_Score=151, Evalue=5e-36,
Organism=Homo sapiens, GI238814322, Length=422, Percent_Identity=25.8293838862559, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI310128103, Length=465, Percent_Identity=28.6021505376344, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI188035924, Length=465, Percent_Identity=28.6021505376344, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI310128093, Length=465, Percent_Identity=28.1720430107527, Blast_Score=149, Evalue=3e-35,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=27.7647058823529, Blast_Score=144, Evalue=8e-34,
Organism=Homo sapiens, GI25777721, Length=444, Percent_Identity=28.8288288288288, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI115387104, Length=440, Percent_Identity=26.8181818181818, Blast_Score=136, Evalue=2e-31,
Organism=Homo sapiens, GI310128091, Length=392, Percent_Identity=29.8469387755102, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI25952152, Length=445, Percent_Identity=27.1910112359551, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI25777726, Length=471, Percent_Identity=24.8407643312102, Blast_Score=126, Evalue=2e-28,
Organism=Homo sapiens, GI310128087, Length=285, Percent_Identity=30.1754385964912, Blast_Score=104, Evalue=7e-22,
Organism=Homo sapiens, GI310128089, Length=331, Percent_Identity=28.7009063444109, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI4502043, Length=346, Percent_Identity=27.1676300578035, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI238814371, Length=346, Percent_Identity=27.1676300578035, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI71773324, Length=348, Percent_Identity=27.0114942528736, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI206597441, Length=339, Percent_Identity=27.4336283185841, Blast_Score=98, Evalue=7e-20,
Organism=Homo sapiens, GI206597439, Length=339, Percent_Identity=27.4336283185841, Blast_Score=98, Evalue=7e-20,
Organism=Homo sapiens, GI22907049, Length=339, Percent_Identity=27.4336283185841, Blast_Score=98, Evalue=7e-20,
Organism=Homo sapiens, GI310128095, Length=318, Percent_Identity=28.9308176100629, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI310128097, Length=266, Percent_Identity=29.6992481203008, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI73695881, Length=336, Percent_Identity=26.7857142857143, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI73695879, Length=336, Percent_Identity=26.7857142857143, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI310128101, Length=220, Percent_Identity=28.6363636363636, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI4557303, Length=338, Percent_Identity=25.1479289940828, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI310128099, Length=219, Percent_Identity=28.7671232876712, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI73466520, Length=338, Percent_Identity=25.1479289940828, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI223972651, Length=425, Percent_Identity=27.0588235294118, Blast_Score=76, Evalue=3e-13,
Organism=Homo sapiens, GI301500698, Length=283, Percent_Identity=25.7950530035336, Blast_Score=71, Evalue=6e-12,
Organism=Escherichia coli, GI1787250, Length=1321, Percent_Identity=77.2899318697956, Blast_Score=2023, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=466, Percent_Identity=30.2575107296137, Blast_Score=185, Evalue=2e-47,
Organism=Escherichia coli, GI1787684, Length=459, Percent_Identity=29.8474945533769, Blast_Score=167, Evalue=4e-42,
Organism=Escherichia coli, GI1787715, Length=459, Percent_Identity=30.9368191721133, Blast_Score=159, Evalue=1e-39,
Organism=Escherichia coli, GI1788042, Length=463, Percent_Identity=30.0215982721382, Blast_Score=157, Evalue=4e-39,
Organism=Escherichia coli, GI1787558, Length=416, Percent_Identity=31.25, Blast_Score=157, Evalue=4e-39,
Organism=Escherichia coli, GI87081896, Length=464, Percent_Identity=29.7413793103448, Blast_Score=157, Evalue=6e-39,
Organism=Escherichia coli, GI87082295, Length=434, Percent_Identity=29.0322580645161, Blast_Score=153, Evalue=7e-38,
Organism=Escherichia coli, GI1786504, Length=453, Percent_Identity=27.1523178807947, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI87081926, Length=434, Percent_Identity=26.2672811059908, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1787653, Length=264, Percent_Identity=24.2424242424242, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534447, Length=460, Percent_Identity=32.3913043478261, Blast_Score=179, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI25144435, Length=450, Percent_Identity=30.6666666666667, Blast_Score=179, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI32564736, Length=431, Percent_Identity=31.0904872389791, Blast_Score=175, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17562198, Length=516, Percent_Identity=28.1007751937984, Blast_Score=167, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=456, Percent_Identity=30.9210526315789, Blast_Score=166, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI133930964, Length=422, Percent_Identity=28.436018957346, Blast_Score=160, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI115532534, Length=347, Percent_Identity=33.7175792507205, Blast_Score=154, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI25143874, Length=504, Percent_Identity=27.3809523809524, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=504, Percent_Identity=27.3809523809524, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17551164, Length=438, Percent_Identity=26.4840182648402, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32564151, Length=419, Percent_Identity=29.8329355608592, Blast_Score=140, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17534119, Length=451, Percent_Identity=27.0509977827051, Blast_Score=135, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=428, Percent_Identity=27.3364485981308, Blast_Score=134, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=447, Percent_Identity=25.0559284116331, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71995613, Length=404, Percent_Identity=24.7524752475248, Blast_Score=111, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71990744, Length=306, Percent_Identity=30.0653594771242, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=345, Percent_Identity=24.0579710144928, Blast_Score=88, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25146394, Length=345, Percent_Identity=24.0579710144928, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32566756, Length=345, Percent_Identity=24.0579710144928, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17564084, Length=341, Percent_Identity=25.8064516129032, Blast_Score=86, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325196, Length=468, Percent_Identity=30.3418803418803, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6323821, Length=474, Percent_Identity=30.168776371308, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6320917, Length=453, Percent_Identity=27.8145695364238, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323822, Length=471, Percent_Identity=28.8747346072187, Blast_Score=171, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6321826, Length=500, Percent_Identity=28.6, Blast_Score=168, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6324950, Length=463, Percent_Identity=26.133909287257, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6319478, Length=454, Percent_Identity=26.6519823788546, Blast_Score=134, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6321828, Length=494, Percent_Identity=23.8866396761134, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323757, Length=331, Percent_Identity=25.0755287009063, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668425, Length=457, Percent_Identity=29.1028446389497, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24668417, Length=457, Percent_Identity=29.1028446389497, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24668413, Length=457, Percent_Identity=29.1028446389497, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129399, Length=431, Percent_Identity=29.9303944315545, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI281362580, Length=452, Percent_Identity=28.3185840707965, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI62472918, Length=452, Percent_Identity=28.3185840707965, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI62472926, Length=452, Percent_Identity=28.3185840707965, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI62472936, Length=452, Percent_Identity=28.3185840707965, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI21356737, Length=452, Percent_Identity=28.3185840707965, Blast_Score=164, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24650465, Length=451, Percent_Identity=27.7161862527716, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24585660, Length=445, Percent_Identity=26.9662921348315, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28571802, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28571800, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28571806, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28571798, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28571796, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28571794, Length=452, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24666674, Length=460, Percent_Identity=27.1739130434783, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574525, Length=508, Percent_Identity=26.5748031496063, Blast_Score=134, Evalue=6e-31,
Organism=Drosophila melanogaster, GI45552499, Length=369, Percent_Identity=27.10027100271, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI281360303, Length=369, Percent_Identity=27.10027100271, Blast_Score=103, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24638878, Length=420, Percent_Identity=24.5238095238095, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638876, Length=420, Percent_Identity=24.5238095238095, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360299, Length=369, Percent_Identity=27.10027100271, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281360297, Length=369, Percent_Identity=27.10027100271, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281360295, Length=369, Percent_Identity=27.10027100271, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24586250, Length=369, Percent_Identity=27.10027100271, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281360301, Length=369, Percent_Identity=27.10027100271, Blast_Score=101, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 141877; Mature: 141746

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTMGVKLDDAARERIKAAASQINRTPHWLIKQAIFSYLDRLDQGETLPELPLSCVDP
CCCCEECEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCC
LPLEIAGTPPQEGHTPFLAFAEQILPQSVLRANITAAYRRAESDAVPMLLEQARLPSSLA
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
KQAYQLAYRLAGQLRGQKNAGGRAGMVQSLLQEFSLSSQEGVALMCLAEALLRIPDKATR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHH
DALIRDKISGGDWQSHLGHSPSLFVNAATWGLLFTGRLVATHSEAHLSHALSRIIGKRGE
HHHHHHCCCCCCHHHHCCCCCCEEEEHHHHHHHHHCHHEEECHHHHHHHHHHHHHCCCCC
PLIRKGVDMAMRLMGEQFVTGETIDEALANAHRLEAKGFSYSYDMLGEAALTSADALAYL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
CSYQQAIHAIGKAANGRGIYEGPGISIKLSALHPRYSRAQYGRVMEELYPTLKSLTLLAR
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYDIAINIDAEEADRLELSLDLLERLCHEPELAGWNGIGFVIQAYQKRCPALIDYLIDLA
HEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ARSQRRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLSVPSLIY
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHC
PQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYQQVVGKVADGKLHRPCRIYA
CCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEE
PVGTHKTLLAYLVRRLLENGANTSFVNRIADTNLPLEELVADPVAAVDQLTAQEGRPGLP
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHCCCCCCC
HPKIPLPRDLYAPGRANAIGLDLSNEQRLASLSCALLNGANQRLVAIPLLEQPCAEGELR
CCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECHHCCCCCCCCC
PLPNPAEPNDIVGYTRDASGQEVEQALASALRNAPIWCATPPQERAAILVRAASLMERQM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHH
PTLMGILVREAGKTFANAIAEVREAVDFLRYYAGQVHASFDNETHRPLGCVVCISPWNFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECCCCCC
LAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQAIAILHDAGVPPGAVQLLPGRGETVGAQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHH
LVNDSRVRGVMFTGSTEVAKRLQRAVADRLDAQGRPTPLIAETGGLNAMIVDSSALTEQV
HHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCHHHHHHH
VTDVVTSAFDSAGQRCSALRLLCLQEEIADHTLTMLRGAMAEYRIGNPERLGCDIGPLID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCC
TEAKSSIEQHILAMRAKGHPVFQAAHSQEEEAQCDARGNFVPPTLIELDSLNELQEEIFG
CHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
PVLHVVRYRREQLDTLLAQINASGYGLTLGVHSRIDETIAHIAHSAHVGNIYVNRNIVGA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCEECEEEECCCEEEE
VVGVQPFGGEGLSGTGPKAGGPLYLYRLLARSPENTLTLGTDASPHQPNNATPPLQALND
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHH
WAADRPALQILCQHYANQCPAAVPRPLGGPTGERNTLLFVPRERVLCAAGNEDDALIQLA
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHH
AVMAVGCHVLWPDTPLHRALHRDLPSAVAACITLSPPESLMAQEFDAAIYHGDSDRLRLL
HHHHHCCEEECCCCHHHHHHHHCCHHHHHHHEECCCHHHHHHHHHHHHEEECCCCCEEEH
SGQIAARSGAIVPLQGLAPGDTQLRLELLVHERALSVNTAAAGGNASLMTLS
HCHHHHCCCCEEEECCCCCCCHHEEHHHHHHHHHHCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
ATTTMGVKLDDAARERIKAAASQINRTPHWLIKQAIFSYLDRLDQGETLPELPLSCVDP
CCCEECEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCC
LPLEIAGTPPQEGHTPFLAFAEQILPQSVLRANITAAYRRAESDAVPMLLEQARLPSSLA
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
KQAYQLAYRLAGQLRGQKNAGGRAGMVQSLLQEFSLSSQEGVALMCLAEALLRIPDKATR
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHH
DALIRDKISGGDWQSHLGHSPSLFVNAATWGLLFTGRLVATHSEAHLSHALSRIIGKRGE
HHHHHHCCCCCCHHHHCCCCCCEEEEHHHHHHHHHCHHEEECHHHHHHHHHHHHHCCCCC
PLIRKGVDMAMRLMGEQFVTGETIDEALANAHRLEAKGFSYSYDMLGEAALTSADALAYL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
CSYQQAIHAIGKAANGRGIYEGPGISIKLSALHPRYSRAQYGRVMEELYPTLKSLTLLAR
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QYDIAINIDAEEADRLELSLDLLERLCHEPELAGWNGIGFVIQAYQKRCPALIDYLIDLA
HEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ARSQRRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKVYTDVSYLACARKLLSVPSLIY
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHC
PQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYQQVVGKVADGKLHRPCRIYA
CCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEE
PVGTHKTLLAYLVRRLLENGANTSFVNRIADTNLPLEELVADPVAAVDQLTAQEGRPGLP
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHCCCCCCC
HPKIPLPRDLYAPGRANAIGLDLSNEQRLASLSCALLNGANQRLVAIPLLEQPCAEGELR
CCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECHHCCCCCCCCC
PLPNPAEPNDIVGYTRDASGQEVEQALASALRNAPIWCATPPQERAAILVRAASLMERQM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHH
PTLMGILVREAGKTFANAIAEVREAVDFLRYYAGQVHASFDNETHRPLGCVVCISPWNFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECCCCCC
LAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQAIAILHDAGVPPGAVQLLPGRGETVGAQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHH
LVNDSRVRGVMFTGSTEVAKRLQRAVADRLDAQGRPTPLIAETGGLNAMIVDSSALTEQV
HHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCHHHHHHH
VTDVVTSAFDSAGQRCSALRLLCLQEEIADHTLTMLRGAMAEYRIGNPERLGCDIGPLID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCC
TEAKSSIEQHILAMRAKGHPVFQAAHSQEEEAQCDARGNFVPPTLIELDSLNELQEEIFG
CHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
PVLHVVRYRREQLDTLLAQINASGYGLTLGVHSRIDETIAHIAHSAHVGNIYVNRNIVGA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCEECEEEECCCEEEE
VVGVQPFGGEGLSGTGPKAGGPLYLYRLLARSPENTLTLGTDASPHQPNNATPPLQALND
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHH
WAADRPALQILCQHYANQCPAAVPRPLGGPTGERNTLLFVPRERVLCAAGNEDDALIQLA
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHH
AVMAVGCHVLWPDTPLHRALHRDLPSAVAACITLSPPESLMAQEFDAAIYHGDSDRLRLL
HHHHHCCEEECCCCHHHHHHHHCCHHHHHHHEECCCHHHHHHHHHHHHEEECCCCCEEEH
SGQIAARSGAIVPLQGLAPGDTQLRLELLVHERALSVNTAAAGGNASLMTLS
HCHHHHCCCCEEEECCCCCCCHHEEHHHHHHHHHHCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]