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The map label for this gene is cusC [H]

Identifier: 238920015

GI number: 238920015

Start: 2040731

End: 2042113

Strand: Reverse

Name: cusC [H]

Synonym: NT01EI_2119

Alternate gene names: 238920015

Gene position: 2042113-2040731 (Counterclockwise)

Preceding gene: 238920018

Following gene: 238920014

Centisome position: 53.57

GC content: 61.32

Gene sequence:

>1383_bases
ATGGTTAAGATAAAGCAATTAAGCGTCAGCATGGTATTGACCCTGACGGGATGTGTCTCTCTGGCGCCAGAGTATCAGCG
CCCGGCATTGCCGGTAGGTGCGCAGTTCTCCTCCGCGGCGGCAGCAGGCGACACGGCGTCGACGTACGACCGGGATCAGG
GCTGGCGCCAGTTCTTTCGCGATGCGCAGGCCAGGTCGCTGATCGACGAGGCGCTGCTCAATAACCGCGACCTGCAGCAG
GCGGTGCTCAATGTGCGTCTGGCGCGCGCCCAGCTGGCGCTGCAGCAGGCCGACCGTTACCCCCAGCTCGACGCCACCTC
GCAGGCAAACTACCGTGCTCCGCTCCAGGGGGGAGCCAGTAACCGGGAGTATCAATTGGGTGGTGCGCTGGGATTCGATC
TGGATCTGTTCGGCCGGCTCCAGTCGATGAGTGCGCGGGAGCAGCAGAATTTTCTCGCCAGTCAGCAGGCGCAGCGTGCG
GTGCATATTCTGTTGGTCTCCAATGTCGCCCAGGCCTATTTTACCCAACAACTGGCCTATGCCCAGCGACGTATCGCCCA
AGAGACGCTGCAAAACTATCGTCAATCCTATTCCCTGATCGAGCAGCAGGTTCGGGCCGGCAGTAATAATCTGCTGGCAT
TAGAGCAGGCGCGCGGGCAGCTCGATACGACCCAGGCGACGCTGGCGCGGCGTGAAGGTGAGGTGGCGCAGGCCAACCAT
GCCATTCAGCGACTCGTCGGTGTCTATGGCGGTACCCCCCGCGATCTGCGCGGGCTGGAGAGCCCGGTTGGCCCGGTAGC
GCTGCCGGTGCCGCTGCCATCGACGATCCTGCTGCAACGTCCCGACATTATGGAGGCGGAGCATCTGCTGCAAGCAGCGG
ATGCCGATATCGGAGCCGCCCGGGCAGCATTCTTTCCCTCTATCTCGCTGAGCGGCGGCTTAAACAGCAGCGGCAGTGAT
CTGGCCGGGCTATTCAGCGCGGCCGGTGGAATGTGGAGTTTTGTCCCCAAGGTTACCCTGCCGATCTTTAATGGCGGGCG
TAACCGCGCCAATCTGCAGCTCGCCGAATTACGCCAGCAGCAGTCCGTCGTGAATTATGAAAATAAGATCCAGGCCGCGT
TTAAGGAGGTGGACGATGCCCTCTCTGCGCGTCGGAGCCTCGCCGATCAATTAACGGCGCAGCAGCGTTATCTCGATGCG
ATCCAGGCAACCTTGGTGCGCGCCCGCGGCCTGTACGCCCACGGTGCGCTGAGTTATCTCGAGGTATTGGACGCAGAACG
CGCGTTATTTACCACCCAACAGACGCTGCTCGATCTGCGTTATTCACAGCAGGCGAATGAAATAACCCTTTTCGCTGCCT
TGGGCGGCGGTTGGCAGGCATAA

Upstream 100 bases:

>100_bases
TCCTGTCACCGGGCAAACCGTATCGGTTTGTTAAGGTGCCATTATCCTTTGGCGGCCTTTAGGGTGCCACCCCCATCGGC
ATGTTTGGGCTATCCGCGTT

Downstream 100 bases:

>100_bases
CAACGGACCCTTAATCCAATGGAGTGAACTTTATGAAAACAGCGTTCAACGTGGTTTTATGTACAGCTTTCATCATGGCG
GGCAGCGTCCCGGTGCTGGC

Product: copper/silver efflux system outer membrane protein CusC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MVKIKQLSVSMVLTLTGCVSLAPEYQRPALPVGAQFSSAAAAGDTASTYDRDQGWRQFFRDAQARSLIDEALLNNRDLQQ
AVLNVRLARAQLALQQADRYPQLDATSQANYRAPLQGGASNREYQLGGALGFDLDLFGRLQSMSAREQQNFLASQQAQRA
VHILLVSNVAQAYFTQQLAYAQRRIAQETLQNYRQSYSLIEQQVRAGSNNLLALEQARGQLDTTQATLARREGEVAQANH
AIQRLVGVYGGTPRDLRGLESPVGPVALPVPLPSTILLQRPDIMEAEHLLQAADADIGAARAAFFPSISLSGGLNSSGSD
LAGLFSAAGGMWSFVPKVTLPIFNGGRNRANLQLAELRQQQSVVNYENKIQAAFKEVDDALSARRSLADQLTAQQRYLDA
IQATLVRARGLYAHGALSYLEVLDAERALFTTQQTLLDLRYSQQANEITLFAALGGGWQA

Sequences:

>Translated_460_residues
MVKIKQLSVSMVLTLTGCVSLAPEYQRPALPVGAQFSSAAAAGDTASTYDRDQGWRQFFRDAQARSLIDEALLNNRDLQQ
AVLNVRLARAQLALQQADRYPQLDATSQANYRAPLQGGASNREYQLGGALGFDLDLFGRLQSMSAREQQNFLASQQAQRA
VHILLVSNVAQAYFTQQLAYAQRRIAQETLQNYRQSYSLIEQQVRAGSNNLLALEQARGQLDTTQATLARREGEVAQANH
AIQRLVGVYGGTPRDLRGLESPVGPVALPVPLPSTILLQRPDIMEAEHLLQAADADIGAARAAFFPSISLSGGLNSSGSD
LAGLFSAAGGMWSFVPKVTLPIFNGGRNRANLQLAELRQQQSVVNYENKIQAAFKEVDDALSARRSLADQLTAQQRYLDA
IQATLVRARGLYAHGALSYLEVLDAERALFTTQQTLLDLRYSQQANEITLFAALGGGWQA
>Mature_460_residues
MVKIKQLSVSMVLTLTGCVSLAPEYQRPALPVGAQFSSAAAAGDTASTYDRDQGWRQFFRDAQARSLIDEALLNNRDLQQ
AVLNVRLARAQLALQQADRYPQLDATSQANYRAPLQGGASNREYQLGGALGFDLDLFGRLQSMSAREQQNFLASQQAQRA
VHILLVSNVAQAYFTQQLAYAQRRIAQETLQNYRQSYSLIEQQVRAGSNNLLALEQARGQLDTTQATLARREGEVAQANH
AIQRLVGVYGGTPRDLRGLESPVGPVALPVPLPSTILLQRPDIMEAEHLLQAADADIGAARAAFFPSISLSGGLNSSGSD
LAGLFSAAGGMWSFVPKVTLPIFNGGRNRANLQLAELRQQQSVVNYENKIQAAFKEVDDALSARRSLADQLTAQQRYLDA
IQATLVRARGLYAHGALSYLEVLDAERALFTTQQTLLDLRYSQQANEITLFAALGGGWQA

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=458, Percent_Identity=59.6069868995633, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI2367348, Length=438, Percent_Identity=24.8858447488584, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50148; Mature: 50148

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]