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The map label for this gene is slyA

Identifier: 238919997

GI number: 238919997

Start: 2022667

End: 2023098

Strand: Reverse

Name: slyA

Synonym: NT01EI_2101

Alternate gene names: 238919997

Gene position: 2023098-2022667 (Counterclockwise)

Preceding gene: 238920001

Following gene: 238919995

Centisome position: 53.07

GC content: 54.63

Gene sequence:

>432_bases
TTGGAATCAACATTGGGGTCGGATTTAGCACGGTTGGTGCGTGTATGGCGTGCCTTGATCGATCAGCGACTGAAGCCGTT
GGAGCTGACGCAGACGCATTGGGTGACGCTGTATAACATTCACCGCTTGCCGCCTGAGCAGTCGCAGATTCAGCTGGCCA
AGGCGATTGGCATTGAGCAGCCGTCGCTGGTGCGTACGCTGGATCAGCTGGAGGATAAGGGGCTGATTACCCGACACACC
TGTGCTAACGATCGCCGTGCCAAACGCATTAAGCTGACGGATGGCGCCGAACCCGTGATTAGGGAAGTGGCCGACGTGAT
TTCGCTGACGCGCTGTGAAATCCTGGACGGTATCTCTGCGGATGAGGTCTCGCTGTTGGCCAACCTGATTGAACGTCTGG
AGCAGAACATTATTCATTTGCAGAATAAATAA

Upstream 100 bases:

>100_bases
CCAAGGGGAACCGCCCGCTGAGTTGTGGTTTCCGGGTACGGACCGGTGATGACGGTGTATCGGGTTTATGGATTGGCTCG
CTCATAATAAGGAGATTAAA

Downstream 100 bases:

>100_bases
ACGCACATCGTTCGAGCAGTCAAAAAAACCGGAAGGCATGCCTCCGGTTTTTTTATTGCATCAGGATCACATTGGCGAGA
CATTAACGGTGCTGCCGCTG

Product: transcriptional regulator SlyA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MESTLGSDLARLVRVWRALIDQRLKPLELTQTHWVTLYNIHRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEDKGLITRHT
CANDRRAKRIKLTDGAEPVIREVADVISLTRCEILDGISADEVSLLANLIERLEQNIIHLQNK

Sequences:

>Translated_143_residues
MESTLGSDLARLVRVWRALIDQRLKPLELTQTHWVTLYNIHRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEDKGLITRHT
CANDRRAKRIKLTDGAEPVIREVADVISLTRCEILDGISADEVSLLANLIERLEQNIIHLQNK
>Mature_143_residues
MESTLGSDLARLVRVWRALIDQRLKPLELTQTHWVTLYNIHRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEDKGLITRHT
CANDRRAKRIKLTDGAEPVIREVADVISLTRCEILDGISADEVSLLANLIERLEQNIIHLQNK

Specific function: Transcription regulator that can both activate or repress expression

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI87081950, Length=143, Percent_Identity=77.6223776223776, Blast_Score=221, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SLYA_EDWI9 (C5BE36)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933512.1
- ProteinModelPortal:   C5BE36
- GeneID:   7959079
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2101
- OMA:   DEHRFGM
- ProtClustDB:   PRK03573
- GO:   GO:0005622
- HAMAP:   MF_01819
- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR023187
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00598
- SMART:   SM00347

Pfam domain/function: PF01047 MarR

EC number: NA

Molecular weight: Translated: 16287; Mature: 16287

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS01117 HTH_MARR_1; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESTLGSDLARLVRVWRALIDQRLKPLELTQTHWVTLYNIHRLPPEQSQIQLAKAIGIEQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEECCCCCHHHHHHHHHHCCCC
PSLVRTLDQLEDKGLITRHTCANDRRAKRIKLTDGAEPVIREVADVISLTRCEILDGISA
CHHHHHHHHHHHCCCEEECCCCCCCHHCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCH
DEVSLLANLIERLEQNIIHLQNK
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESTLGSDLARLVRVWRALIDQRLKPLELTQTHWVTLYNIHRLPPEQSQIQLAKAIGIEQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEECCCCCHHHHHHHHHHCCCC
PSLVRTLDQLEDKGLITRHTCANDRRAKRIKLTDGAEPVIREVADVISLTRCEILDGISA
CHHHHHHHHHHHCCCEEECCCCCCCHHCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCH
DEVSLLANLIERLEQNIIHLQNK
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA