Click here to switch to the map view.

The map label for this gene is pdxY [H]

Identifier: 238919991

GI number: 238919991

Start: 2016967

End: 2017833

Strand: Reverse

Name: pdxY [H]

Synonym: NT01EI_2095

Alternate gene names: 238919991

Gene position: 2017833-2016967 (Counterclockwise)

Preceding gene: 238919992

Following gene: 238919979

Centisome position: 52.93

GC content: 61.48

Gene sequence:

>867_bases
ATGAAGAATATCCTTTCCATTCAATCTCACGTGGTGTTTGGCCACGCCGGTAACAGCGCCGCCGTTTTCCCGATGCGTCG
TATGGGCGTTAACGTATGGCCGCTGAATACCGTTCAGTTCTCTAACCATACTCAGTACGGTCACTGGACCGGCAGCGTGA
TGCCGGCTAATCATCTGACCGAGATTGTGCAAGGGATTGCCGATATTGGGGAGCTGACGCGCTGCAACGCGGTGCTGAGC
GGCTACATTGGTTCGCCGCAGCAGGGCGAGCATATTTTGCAGATCGTTCGACAGGTGAAGCAGAGTAACCCCGACGCATG
GTATTTTTGTGATCCGGTGATGGGACACCCGGAAAAAGGGTGCATCGTCGCGCCGGGCGTGGCGGAGTTCTTCTGCCAGC
AGGCGGTCGCCTGCAGCGATATCATGGCGCCCAATCTGCTGGAGCTGGAGACGCTGACCGATCGTAAGATAACCAGCGTC
GAGGAGGCCCTGGCGGCCTCCCGCGCGCTGATCGCCTGCGGCCCACGCATTGTCTTGGTCAAACACCTGCACAATGCCGG
CTACGATCGCAACCGCTTTGAAATGCTGCTGGTCACCGCCGACGAGGCCTGGCACATCGCCCGTCCGCTGGTGGACTTCG
GCGCCCGCCAGCCGGTGGGCGTTGGCGATTTGACCAGTGGTCTGCTGCTGGTGAACCTGCTGAAGGGCGAGTCGCTGCAG
AGCGCGCTGGAGCACGTTACGGCGGCGGTCTATGAGGTGATGCTGACGACCCAGGCGATGGGGGAGTACGAGCTGCAGCT
GGTCGCCGCCCAGGATCGCATCGCCTGTCCGCAGCACCGCTATACGGCGCAGGCGCTGCACGGCTGA

Upstream 100 bases:

>100_bases
AACTATTGCCTGATCTGCTGGAAGTAATCACAGCAAGCAAGGGGGCTGCGGCCCCGGTTAATACCAACGGCTGCCCTGTG
GGCAGATAAGCAAAAATACG

Downstream 100 bases:

>100_bases
TCCCGGGCGATCCGCAAAAAACGAGGCCTCCCCTGGGAGGCCTTTTTACTTGTCTGCTGCGCGCTCAGGGTCGGTCGCGC
TACTTCAACCCCTCGGCGCA

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKNILSIQSHVVFGHAGNSAAVFPMRRMGVNVWPLNTVQFSNHTQYGHWTGSVMPANHLTEIVQGIADIGELTRCNAVLS
GYIGSPQQGEHILQIVRQVKQSNPDAWYFCDPVMGHPEKGCIVAPGVAEFFCQQAVACSDIMAPNLLELETLTDRKITSV
EEALAASRALIACGPRIVLVKHLHNAGYDRNRFEMLLVTADEAWHIARPLVDFGARQPVGVGDLTSGLLLVNLLKGESLQ
SALEHVTAAVYEVMLTTQAMGEYELQLVAAQDRIACPQHRYTAQALHG

Sequences:

>Translated_288_residues
MKNILSIQSHVVFGHAGNSAAVFPMRRMGVNVWPLNTVQFSNHTQYGHWTGSVMPANHLTEIVQGIADIGELTRCNAVLS
GYIGSPQQGEHILQIVRQVKQSNPDAWYFCDPVMGHPEKGCIVAPGVAEFFCQQAVACSDIMAPNLLELETLTDRKITSV
EEALAASRALIACGPRIVLVKHLHNAGYDRNRFEMLLVTADEAWHIARPLVDFGARQPVGVGDLTSGLLLVNLLKGESLQ
SALEHVTAAVYEVMLTTQAMGEYELQLVAAQDRIACPQHRYTAQALHG
>Mature_288_residues
MKNILSIQSHVVFGHAGNSAAVFPMRRMGVNVWPLNTVQFSNHTQYGHWTGSVMPANHLTEIVQGIADIGELTRCNAVLS
GYIGSPQQGEHILQIVRQVKQSNPDAWYFCDPVMGHPEKGCIVAPGVAEFFCQQAVACSDIMAPNLLELETLTDRKITSV
EEALAASRALIACGPRIVLVKHLHNAGYDRNRFEMLLVTADEAWHIARPLVDFGARQPVGVGDLTSGLLLVNLLKGESLQ
SALEHVTAAVYEVMLTTQAMGEYELQLVAAQDRIACPQHRYTAQALHG

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=180, Percent_Identity=38.3333333333333, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1787924, Length=286, Percent_Identity=75.1748251748252, Blast_Score=449, Evalue=1e-128,
Organism=Escherichia coli, GI1788758, Length=266, Percent_Identity=30.0751879699248, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17507759, Length=289, Percent_Identity=29.757785467128, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17507757, Length=299, Percent_Identity=29.0969899665552, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324354, Length=272, Percent_Identity=31.25, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320806, Length=301, Percent_Identity=28.9036544850498, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45553007, Length=303, Percent_Identity=30.3630363036304, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31472; Mature: 31472

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILSIQSHVVFGHAGNSAAVFPMRRMGVNVWPLNTVQFSNHTQYGHWTGSVMPANHLT
CCCHHEEHHEEEEEECCCCEEECCHHHCCCEEECCCEEEECCCCCCCCCCCCCCCHHHHH
EIVQGIADIGELTRCNAVLSGYIGSPQQGEHILQIVRQVKQSNPDAWYFCDPVMGHPEKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
CIVAPGVAEFFCQQAVACSDIMAPNLLELETLTDRKITSVEEALAASRALIACGPRIVLV
CEECCCHHHHHHHHHHHHHHHCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEE
KHLHNAGYDRNRFEMLLVTADEAWHIARPLVDFGARQPVGVGDLTSGLLLVNLLKGESLQ
EHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHH
SALEHVTAAVYEVMLTTQAMGEYELQLVAAQDRIACPQHRYTAQALHG
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MKNILSIQSHVVFGHAGNSAAVFPMRRMGVNVWPLNTVQFSNHTQYGHWTGSVMPANHLT
CCCHHEEHHEEEEEECCCCEEECCHHHCCCEEECCCEEEECCCCCCCCCCCCCCCHHHHH
EIVQGIADIGELTRCNAVLSGYIGSPQQGEHILQIVRQVKQSNPDAWYFCDPVMGHPEKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
CIVAPGVAEFFCQQAVACSDIMAPNLLELETLTDRKITSVEEALAASRALIACGPRIVLV
CEECCCHHHHHHHHHHHHHHHCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEE
KHLHNAGYDRNRFEMLLVTADEAWHIARPLVDFGARQPVGVGDLTSGLLLVNLLKGESLQ
EHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHH
SALEHVTAAVYEVMLTTQAMGEYELQLVAAQDRIACPQHRYTAQALHG
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA