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The map label for this gene is aegA [H]

Identifier: 238919824

GI number: 238919824

Start: 1855771

End: 1857807

Strand: Reverse

Name: aegA [H]

Synonym: NT01EI_1928

Alternate gene names: 238919824

Gene position: 1857807-1855771 (Counterclockwise)

Preceding gene: 238919826

Following gene: 238919821

Centisome position: 48.73

GC content: 63.38

Gene sequence:

>2037_bases
ATGAATCGTTTTGTCATTGCCGATGCCAACAACTGCATCGGTTGCCGTAGCTGTGAAGTCGCCTGCGTAATGGCCCACAA
CCACGGTGAGCATGTTCTCACGGCGGCGCAGTTTCAGCCGCGCATCCACGTTATCCACCGCGGCGATCGCCGCACCGCGC
TGCTGTGCCGTCACTGCGAAGATGCGCCCTGTGCCAATGTCTGCCCCAATGGCGCCATTGAAAAATACAACGACAGCATC
CAGGTCAGGCAGGAGAAATGTATCGGTTGCAAAACCTGCGTCGTCGCCTGCCCGTTTGGTGCCATCGAGGTGATTACTCA
GTCCGACCCGCGCAGCAATCACCCTGACAGCGTGCGCGCCAACGCCCATAAGTGCGATCTGTGTGACGGGGTAGCCGATA
GCCCCTCCTGCGTCGCTGCCTGTCCCAGCAATGCCCTGCAGCTGATCAGCGAAGACTCCCTGACCCGGCTGCGTCAGCAG
CGTCAGCTGCGCGCCGTGTTCAACGAGCAGGCCGGACGGATATTTAACGGCAGCGCGGCGGCCGATGCCCGCGGTGCCGC
ACTCGGCGGCAGCGGCGGCAGTAAGGTGGCGCTGATGCGTCAGACCCCACCGCGCCAGGATCCGGTCAAGATCGCACTGG
CTATCCGCAAAGCCCGCTTCGACGAAATCTACCCAACCTTTGCCCCCCAGCAGGCGCAGGCGCAGAGCGAACGCTGCCTG
GCCTGCGGCACCCACAGCGTCTGCGAGTGGACCTGTCCGCTGCACAACCATATTCCGCACTGGATCCGCCTGGTAAAAGA
GGGGCGGATCCTTGAGGCCGCCGAACTCTCCCACCAAACCAACTGCCTGCCGGAGGTGACCGGCCGCGTCTGTCCGCAGG
ATCGCCTGTGCGAGGGCGCCTGTACGCTGGGGACAGAGTTCGGCGCCATGACCATCGGCAACATTGAGCGCTACATCAGC
GACAGCGCCTTCGCCCTGGGCTGGCGCCCCGACCTCTCCTATGTCAGGCCGGTCAACCGTCGCGTCGCCATAGTCGGTGC
CGGCCCCGCCGGACTGGGCTGCGCCGATATTCTGGCCCGTAACGGCATTCAGGCGGTGGTGTTCGATCGCCATCCGGAAA
TCGGCGGCCTGCTCACCTTCGGTATTCCGGCGTTTAAGCTGGATAAATCGATCCTGGCGCGGCGTCGGGAGATCTTCAGC
GATATGGGTATCGAGTTCCACCTGAACACGGAGGTGGGACGTGACGTCACCCTGGAGCAGCTGCTGTCCGACTTTGACGC
TGTGTTTATCGGCGCAGGTACCTACACCTCCATGCAGGCGGGAATAGAAAACGAGCAGGCGCCGGGGGTCTATGAGGCCC
TGCCATTCCTGATCGCCAATACCAAACAGGTGATGGGTCTGCCGCCCAGCGATGATGAACCCTATATCAGCATGGAAGGT
AAGCAGGTAGTGGTGCTGGGGGGCGGCGATACCGCCATGGACTGCGTGCGCACCTCCATCCGCCAAGGTGCCACCCGGGT
AACCTGTGCCTATCGCCGCGACGAGGCCAATATGCCCGGCTCGAAAAAAGAGGTGAAAAATGCGCGTGAAGAGGGGGTCG
AGTTCGAATTTAACGTGCAGCCCCTCTCCATCGCCGTCGACGGGCAGGGCAAGGTCTGCGGGATCCACATGCTGCGCACC
GCGCTGGGCGAGCCAGATGCCGCTGGACGCCGCCGTCCCAAACCCATCCCCGGATCTGAGTTTCTCATGCCGGCCGATGC
GGTGGTGATCGCCTTCGGCTTCACCCCGCACTCCATGCCGTGGCTGGAGGCGCAGGGAGTAAAAGTTGATCGTGCGGGGC
GTATCATCGCCCGCGTAGACAGCGATATCCCCTATCAGACCAGCCATCCGCAGATCTTCGCCGGTGGCGATGCGGTACGC
GGCGCCGATCTGGTGGTCACCGCCATCGCCGAAGGGCGCCACGCCGCCGCCGGCATGATGCGCTACTTTGGCGTTGAGAC
GCAGCGTCCGCGCATCCGCCCGCAGGATGTCGCCTGA

Upstream 100 bases:

>100_bases
GGTTTCCTTGTCGTTAATAAATGTTTTCCAGTCATTTGTGCACGCGATGTGCATATATCCCAAACATGTTGTCTCCTTTT
CGTCTTTGGGTGAGGTCGTT

Downstream 100 bases:

>100_bases
TCGCAGATGCGTTGCCCGCGAAACAGCGGGCACAATCTCCTTTAGCTCGGGGGAGCGGCTCGAATCAGAATCGAACCGCT
CCCTTGTCCATCAGTGCGAC

Product: glutamate synthase family, small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MNRFVIADANNCIGCRSCEVACVMAHNHGEHVLTAAQFQPRIHVIHRGDRRTALLCRHCEDAPCANVCPNGAIEKYNDSI
QVRQEKCIGCKTCVVACPFGAIEVITQSDPRSNHPDSVRANAHKCDLCDGVADSPSCVAACPSNALQLISEDSLTRLRQQ
RQLRAVFNEQAGRIFNGSAAADARGAALGGSGGSKVALMRQTPPRQDPVKIALAIRKARFDEIYPTFAPQQAQAQSERCL
ACGTHSVCEWTCPLHNHIPHWIRLVKEGRILEAAELSHQTNCLPEVTGRVCPQDRLCEGACTLGTEFGAMTIGNIERYIS
DSAFALGWRPDLSYVRPVNRRVAIVGAGPAGLGCADILARNGIQAVVFDRHPEIGGLLTFGIPAFKLDKSILARRREIFS
DMGIEFHLNTEVGRDVTLEQLLSDFDAVFIGAGTYTSMQAGIENEQAPGVYEALPFLIANTKQVMGLPPSDDEPYISMEG
KQVVVLGGGDTAMDCVRTSIRQGATRVTCAYRRDEANMPGSKKEVKNAREEGVEFEFNVQPLSIAVDGQGKVCGIHMLRT
ALGEPDAAGRRRPKPIPGSEFLMPADAVVIAFGFTPHSMPWLEAQGVKVDRAGRIIARVDSDIPYQTSHPQIFAGGDAVR
GADLVVTAIAEGRHAAAGMMRYFGVETQRPRIRPQDVA

Sequences:

>Translated_678_residues
MNRFVIADANNCIGCRSCEVACVMAHNHGEHVLTAAQFQPRIHVIHRGDRRTALLCRHCEDAPCANVCPNGAIEKYNDSI
QVRQEKCIGCKTCVVACPFGAIEVITQSDPRSNHPDSVRANAHKCDLCDGVADSPSCVAACPSNALQLISEDSLTRLRQQ
RQLRAVFNEQAGRIFNGSAAADARGAALGGSGGSKVALMRQTPPRQDPVKIALAIRKARFDEIYPTFAPQQAQAQSERCL
ACGTHSVCEWTCPLHNHIPHWIRLVKEGRILEAAELSHQTNCLPEVTGRVCPQDRLCEGACTLGTEFGAMTIGNIERYIS
DSAFALGWRPDLSYVRPVNRRVAIVGAGPAGLGCADILARNGIQAVVFDRHPEIGGLLTFGIPAFKLDKSILARRREIFS
DMGIEFHLNTEVGRDVTLEQLLSDFDAVFIGAGTYTSMQAGIENEQAPGVYEALPFLIANTKQVMGLPPSDDEPYISMEG
KQVVVLGGGDTAMDCVRTSIRQGATRVTCAYRRDEANMPGSKKEVKNAREEGVEFEFNVQPLSIAVDGQGKVCGIHMLRT
ALGEPDAAGRRRPKPIPGSEFLMPADAVVIAFGFTPHSMPWLEAQGVKVDRAGRIIARVDSDIPYQTSHPQIFAGGDAVR
GADLVVTAIAEGRHAAAGMMRYFGVETQRPRIRPQDVA
>Mature_678_residues
MNRFVIADANNCIGCRSCEVACVMAHNHGEHVLTAAQFQPRIHVIHRGDRRTALLCRHCEDAPCANVCPNGAIEKYNDSI
QVRQEKCIGCKTCVVACPFGAIEVITQSDPRSNHPDSVRANAHKCDLCDGVADSPSCVAACPSNALQLISEDSLTRLRQQ
RQLRAVFNEQAGRIFNGSAAADARGAALGGSGGSKVALMRQTPPRQDPVKIALAIRKARFDEIYPTFAPQQAQAQSERCL
ACGTHSVCEWTCPLHNHIPHWIRLVKEGRILEAAELSHQTNCLPEVTGRVCPQDRLCEGACTLGTEFGAMTIGNIERYIS
DSAFALGWRPDLSYVRPVNRRVAIVGAGPAGLGCADILARNGIQAVVFDRHPEIGGLLTFGIPAFKLDKSILARRREIFS
DMGIEFHLNTEVGRDVTLEQLLSDFDAVFIGAGTYTSMQAGIENEQAPGVYEALPFLIANTKQVMGLPPSDDEPYISMEG
KQVVVLGGGDTAMDCVRTSIRQGATRVTCAYRRDEANMPGSKKEVKNAREEGVEFEFNVQPLSIAVDGQGKVCGIHMLRT
ALGEPDAAGRRRPKPIPGSEFLMPADAVVIAFGFTPHSMPWLEAQGVKVDRAGRIIARVDSDIPYQTSHPQIFAGGDAVR
GADLVVTAIAEGRHAAAGMMRYFGVETQRPRIRPQDVA

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=462, Percent_Identity=29.2207792207792, Blast_Score=162, Evalue=9e-40,
Organism=Escherichia coli, GI1788811, Length=667, Percent_Identity=64.0179910044978, Blast_Score=894, Evalue=0.0,
Organism=Escherichia coli, GI87082180, Length=664, Percent_Identity=53.3132530120482, Blast_Score=735, Evalue=0.0,
Organism=Escherichia coli, GI1789606, Length=461, Percent_Identity=69.6312364425163, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1789067, Length=173, Percent_Identity=50.2890173410405, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1788468, Length=449, Percent_Identity=30.0668151447661, Blast_Score=169, Evalue=7e-43,
Organism=Escherichia coli, GI1789243, Length=421, Percent_Identity=31.353919239905, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI2367245, Length=164, Percent_Identity=48.1707317073171, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI87082179, Length=161, Percent_Identity=42.2360248447205, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789079, Length=210, Percent_Identity=36.1904761904762, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI87082114, Length=188, Percent_Identity=37.7659574468085, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787122, Length=167, Percent_Identity=33.5329341317365, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787749, Length=195, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790326, Length=178, Percent_Identity=30.8988764044944, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787872, Length=167, Percent_Identity=32.3353293413174, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI2367345, Length=161, Percent_Identity=33.5403726708075, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787963, Length=163, Percent_Identity=32.5153374233129, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI226510944, Length=163, Percent_Identity=33.7423312883436, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17570289, Length=501, Percent_Identity=34.3313373253493, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71984108, Length=466, Percent_Identity=31.5450643776824, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17543860, Length=174, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320030, Length=467, Percent_Identity=32.5481798715203, Blast_Score=213, Evalue=6e-56,
Organism=Drosophila melanogaster, GI28574881, Length=499, Percent_Identity=36.0721442885772, Blast_Score=262, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24665539, Length=499, Percent_Identity=36.0721442885772, Blast_Score=262, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24665547, Length=499, Percent_Identity=36.0721442885772, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24665543, Length=499, Percent_Identity=36.0721442885772, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24640763, Length=462, Percent_Identity=28.7878787878788, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI18858217, Length=462, Percent_Identity=28.7878787878788, Blast_Score=148, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 73493; Mature: 73493

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFVIADANNCIGCRSCEVACVMAHNHGEHVLTAAQFQPRIHVIHRGDRRTALLCRHCE
CCEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEECCCCCHHHHHHCCC
DAPCANVCPNGAIEKYNDSIQVRQEKCIGCKTCVVACPFGAIEVITQSDPRSNHPDSVRA
CCCCCCCCCCCCHHHCCCCCEEHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCC
NAHKCDLCDGVADSPSCVAACPSNALQLISEDSLTRLRQQRQLRAVFNEQAGRIFNGSAA
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCC
ADARGAALGGSGGSKVALMRQTPPRQDPVKIALAIRKARFDEIYPTFAPQQAQAQSERCL
CCCCCCEECCCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHHCCCCCCCCHHHHHHCCEE
ACGTHSVCEWTCPLHNHIPHWIRLVKEGRILEAAELSHQTNCLPEVTGRVCPQDRLCEGA
ECCCCCCEEEECCHHHCCHHHHHHHHCCCEEEHHHHHHHCCCCHHHHCCCCCHHHHCCCH
CTLGTEFGAMTIGNIERYISDSAFALGWRPDLSYVRPVNRRVAIVGAGPAGLGCADILAR
HHCCCCCCCEEHHHHHHHHCCCCEEEECCCCCHHHCCCCCEEEEEECCCCCCCHHHHHHC
NGIQAVVFDRHPEIGGLLTFGIPAFKLDKSILARRREIFSDMGIEFHLNTEVGRDVTLEQ
CCCEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHH
LLSDFDAVFIGAGTYTSMQAGIENEQAPGVYEALPFLIANTKQVMGLPPSDDEPYISMEG
HHHHCCEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCCEEEECC
KQVVVLGGGDTAMDCVRTSIRQGATRVTCAYRRDEANMPGSKKEVKNAREEGVEFEFNVQ
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECE
PLSIAVDGQGKVCGIHMLRTALGEPDAAGRRRPKPIPGSEFLMPADAVVIAFGFTPHSMP
EEEEEECCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCC
WLEAQGVKVDRAGRIIARVDSDIPYQTSHPQIFAGGDAVRGADLVVTAIAEGRHAAAGMM
CEECCCEEECCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHH
RYFGVETQRPRIRPQDVA
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRFVIADANNCIGCRSCEVACVMAHNHGEHVLTAAQFQPRIHVIHRGDRRTALLCRHCE
CCEEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCEEEEEECCCCCHHHHHHCCC
DAPCANVCPNGAIEKYNDSIQVRQEKCIGCKTCVVACPFGAIEVITQSDPRSNHPDSVRA
CCCCCCCCCCCCHHHCCCCCEEHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCC
NAHKCDLCDGVADSPSCVAACPSNALQLISEDSLTRLRQQRQLRAVFNEQAGRIFNGSAA
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCC
ADARGAALGGSGGSKVALMRQTPPRQDPVKIALAIRKARFDEIYPTFAPQQAQAQSERCL
CCCCCCEECCCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHHCCCCCCCCHHHHHHCCEE
ACGTHSVCEWTCPLHNHIPHWIRLVKEGRILEAAELSHQTNCLPEVTGRVCPQDRLCEGA
ECCCCCCEEEECCHHHCCHHHHHHHHCCCEEEHHHHHHHCCCCHHHHCCCCCHHHHCCCH
CTLGTEFGAMTIGNIERYISDSAFALGWRPDLSYVRPVNRRVAIVGAGPAGLGCADILAR
HHCCCCCCCEEHHHHHHHHCCCCEEEECCCCCHHHCCCCCEEEEEECCCCCCCHHHHHHC
NGIQAVVFDRHPEIGGLLTFGIPAFKLDKSILARRREIFSDMGIEFHLNTEVGRDVTLEQ
CCCEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHH
LLSDFDAVFIGAGTYTSMQAGIENEQAPGVYEALPFLIANTKQVMGLPPSDDEPYISMEG
HHHHCCEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCCCCEEEECC
KQVVVLGGGDTAMDCVRTSIRQGATRVTCAYRRDEANMPGSKKEVKNAREEGVEFEFNVQ
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEECE
PLSIAVDGQGKVCGIHMLRTALGEPDAAGRRRPKPIPGSEFLMPADAVVIAFGFTPHSMP
EEEEEECCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCCCC
WLEAQGVKVDRAGRIIARVDSDIPYQTSHPQIFAGGDAVRGADLVVTAIAEGRHAAAGMM
CEECCCEEECCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHH
RYFGVETQRPRIRPQDVA
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]