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The map label for this gene is btuC [H]

Identifier: 238919790

GI number: 238919790

Start: 1823284

End: 1824240

Strand: Direct

Name: btuC [H]

Synonym: NT01EI_1894

Alternate gene names: 238919790

Gene position: 1823284-1824240 (Clockwise)

Preceding gene: 238919789

Following gene: 238919791

Centisome position: 47.83

GC content: 64.99

Gene sequence:

>957_bases
TTGACGTTGCTGGCACTGCTGCTGCTGGCGGCGCTAATGCTGGGGTTGAGCGCTGGTGATATCTGGCTGTGGCCAACGCA
ATGGTTCACCCCCGACGGGCAGTTGTTCGTCGGGCAGCTGCGTCTGCCACGGGTGCTGGCGGTGATGGCGGTCGGCGCGG
CGCTGGCGGTTAGCGGGGCAGTGATGCAGGCGTTGTTTGACAATACCCTGGCCGAGCCGGGGCTGCTGGGCGTCTCTAAC
GGTGCCGGCGTGGCCTTGGTGATCGCGGTGCTGCTGGGGCAGAATTTGATGCCGATGTGGCTGCTCAGCGCGCTGGCCAT
CGTCGGCGCGTTGACTATTACCCTGTTGTTGATGCTGTTTGCCCGCCGTGGGCGGTTGAACAACGCCCGGCTGCTGCTGA
TCGGCGTCGCGCTGGGGATCGCCTGCAGCGCCGCCATGACCTGGGCGGTCTACTTTAGCAGCAGCCTGGATCTGCGCCAG
CTGCTCTACTGGTTGATGGGCGGCTTCAGCGGCATCGACTGGCGTCAGGGGTGGCTGATGGGCGCGCTGCTGCCGGTGCT
GCTGTGGCTGCTGACTCGTGGTGATATTCTGAATCTGATGGCGCTGGGGGAGCTGCCTGCCCGTCAGCTGGGGCTGGGCA
TGACCCACTGGCGTAGCCTGCTGGTGCTGGCTATCGGCTGGCTGGTCGGGGTGAGCGTCGCGCTGGCCGGTGTGATCGGC
TTTGTCGGCCTGGTGGTGCCCCATATGCTGCGCCTGTGGGGCATCACCCAGCACAGAATGCTGCTTCCGGGCTGCGCGCT
GGCGGGCGCCTCGATGCTGCTGCTGGCGGACGTCGTGGCGCGGATCGCACTGTTTTCTGCCGAGTTGCCGATCGGGGTGG
TGACCTCATCAATTGGTGCACCGCTGTTTATCTGGATGCTACTGCGGCGCTCATCAGGGGGAATCAATGTACGATAA

Upstream 100 bases:

>100_bases
GGTATCTTTGTTGAGCCGTATGATGACGATGTGTCAGCCTGACGCAGTGCCCACCTTCAGCGGTCTGATCCAACGCCAGC
GGCGGCGGGACCGTCGCTGC

Downstream 100 bases:

>100_bases
TGGGCTGCGTATCGATGGTGTGGCAGTTTCCGGCCGGTTGGCGCCCCTGAGTGCGTTGGTGGCGCGCGGACGGTTGGTGC
ATATCATCGGCCCGAACGGT

Product: vtamin B12-transporter permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MTLLALLLLAALMLGLSAGDIWLWPTQWFTPDGQLFVGQLRLPRVLAVMAVGAALAVSGAVMQALFDNTLAEPGLLGVSN
GAGVALVIAVLLGQNLMPMWLLSALAIVGALTITLLLMLFARRGRLNNARLLLIGVALGIACSAAMTWAVYFSSSLDLRQ
LLYWLMGGFSGIDWRQGWLMGALLPVLLWLLTRGDILNLMALGELPARQLGLGMTHWRSLLVLAIGWLVGVSVALAGVIG
FVGLVVPHMLRLWGITQHRMLLPGCALAGASMLLLADVVARIALFSAELPIGVVTSSIGAPLFIWMLLRRSSGGINVR

Sequences:

>Translated_318_residues
MTLLALLLLAALMLGLSAGDIWLWPTQWFTPDGQLFVGQLRLPRVLAVMAVGAALAVSGAVMQALFDNTLAEPGLLGVSN
GAGVALVIAVLLGQNLMPMWLLSALAIVGALTITLLLMLFARRGRLNNARLLLIGVALGIACSAAMTWAVYFSSSLDLRQ
LLYWLMGGFSGIDWRQGWLMGALLPVLLWLLTRGDILNLMALGELPARQLGLGMTHWRSLLVLAIGWLVGVSVALAGVIG
FVGLVVPHMLRLWGITQHRMLLPGCALAGASMLLLADVVARIALFSAELPIGVVTSSIGAPLFIWMLLRRSSGGINVR
>Mature_317_residues
TLLALLLLAALMLGLSAGDIWLWPTQWFTPDGQLFVGQLRLPRVLAVMAVGAALAVSGAVMQALFDNTLAEPGLLGVSNG
AGVALVIAVLLGQNLMPMWLLSALAIVGALTITLLLMLFARRGRLNNARLLLIGVALGIACSAAMTWAVYFSSSLDLRQL
LYWLMGGFSGIDWRQGWLMGALLPVLLWLLTRGDILNLMALGELPARQLGLGMTHWRSLLVLAIGWLVGVSVALAGVIGF
VGLVVPHMLRLWGITQHRMLLPGCALAGASMLLLADVVARIALFSAELPIGVVTSSIGAPLFIWMLLRRSSGGINVR

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG4139

COG function: function code H; ABC-type cobalamin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=293, Percent_Identity=68.9419795221843, Blast_Score=356, Evalue=1e-99,
Organism=Escherichia coli, GI1790740, Length=286, Percent_Identity=40.2097902097902, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=34.6428571428571, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786347, Length=275, Percent_Identity=33.4545454545455, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786805, Length=283, Percent_Identity=37.8091872791519, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786804, Length=315, Percent_Identity=33.015873015873, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33842; Mature: 33711

Theoretical pI: Translated: 11.64; Mature: 11.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLALLLLAALMLGLSAGDIWLWPTQWFTPDGQLFVGQLRLPRVLAVMAVGAALAVSGA
CHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
VMQALFDNTLAEPGLLGVSNGAGVALVIAVLLGQNLMPMWLLSALAIVGALTITLLLMLF
HHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARRGRLNNARLLLIGVALGIACSAAMTWAVYFSSSLDLRQLLYWLMGGFSGIDWRQGWLM
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHH
GALLPVLLWLLTRGDILNLMALGELPARQLGLGMTHWRSLLVLAIGWLVGVSVALAGVIG
HHHHHHHHHHHCCCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGLVVPHMLRLWGITQHRMLLPGCALAGASMLLLADVVARIALFSAELPIGVVTSSIGA
HHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCH
PLFIWMLLRRSSGGINVR
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TLLALLLLAALMLGLSAGDIWLWPTQWFTPDGQLFVGQLRLPRVLAVMAVGAALAVSGA
HHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
VMQALFDNTLAEPGLLGVSNGAGVALVIAVLLGQNLMPMWLLSALAIVGALTITLLLMLF
HHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARRGRLNNARLLLIGVALGIACSAAMTWAVYFSSSLDLRQLLYWLMGGFSGIDWRQGWLM
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHH
GALLPVLLWLLTRGDILNLMALGELPARQLGLGMTHWRSLLVLAIGWLVGVSVALAGVIG
HHHHHHHHHHHCCCCHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGLVVPHMLRLWGITQHRMLLPGCALAGASMLLLADVVARIALFSAELPIGVVTSSIGA
HHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCH
PLFIWMLLRRSSGGINVR
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA