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The map label for this gene is ptrB [H]

Identifier: 238919769

GI number: 238919769

Start: 1804500

End: 1806554

Strand: Direct

Name: ptrB [H]

Synonym: NT01EI_1873

Alternate gene names: 238919769

Gene position: 1804500-1806554 (Clockwise)

Preceding gene: 238919768

Following gene: 238919770

Centisome position: 47.33

GC content: 59.17

Gene sequence:

>2055_bases
ATGAAAAAGGCACCAAAAGCAGCAAAACATCCCTATGAGATCGTGATGCACGGGGATCGCCGGGTTGATGATTATTACTG
GCTGCGCGACGACACCCGCAGCGATCCACAGGTGTTAGCCTACCTTAACGCGGAAAACGCCTACAGCGAGCGCTGTTTGG
CGCCGCAGTCGGCGCTGCGATCGGCGCTCTTGGCAGAGATGGTGGCGCGTATTCCCCAGCAGGATGCCTCCGTTCCCTAT
GTGCGCAACGGTTACCGCTACCAGCACCGCTACCGGCCCGCCGCCGAATATGCCGAATATTGGCGCCAGCCTGAGTCGGC
GTGCCCAGAGAACGAGACGGCGTGGCAGCGGCTGCTGGATACCAATCAGCGTGCTGAGGGGCATGATTTTTATGCACTGG
GCGCGCTGGAGGTCAGCCCGGATAACCGCCTGCTGGCCATCAGCGAGGATACGGTGTCCCGGCGACAATATACGCTGCGT
GTAAAATCCCTGATGGATGACATCTGGCTGGAGGAGTCGATCGAAGGGTGCGATGGGCATATCGAATGGTGTAACGACTC
CCGCGCCTTTTACTATATCCGCCTGGATCCACAGACCCTGTTGCCTTATCAGATCTATCGCCACCGTCTGGGCACGCCCT
GCAGCCAGGATTGCCTGATCTATCAGGAGTTGGATGACGCGTTTTACCTGGGGCTGGAGAAGTCGCTCTCCCAGCGCTAC
GTGATGATCCATATCAGCAGCACCACAACCTCCGAGGTTTTGCTGCTGGATGCCGATGACCCCGAGGCGCGGGCGCACTG
CTTCCAGCCGCGTAGGCGCGACCACGAGTATTCGCTGGAGCACTATGACTCGCGTTTTTATATCCGATCTAACCGGGAAG
GGCAGAATTTTGCCCTGTACTGTGGACCGGATGGCGATGTACTGAGCTGGCAGACGCTGGTGCCGCCCCGCGATGCGGTC
ATGCTGGAGGACTTCTGTCTGTTTCAGGAGTGGCTGGTGGTGGAGGAGCGCACCCACGGTTTGACGACGCTGCGCCAGAT
CCGTCGCGATGACGGAGAGGAGCGACTGATCCATTTCGACGATCCAACCTATGTCACCTGGTTGGGCTATAACCCGCAGC
CAGAGATTGCCAAACTGCGCTACGGCTACGCATCAATGACGACGCCGGGCAGTGTCTATGAGCTGGATTTGAACAGCGGT
GAGCGGCGCCTGCTGAAGCAGCAGAGCGTGGCGGAATTTAGCGCGCAGGACTACGCCAGCGAACGCATCTGGCTGCGGGC
GCGGGACGGCGTGGATGTGCCGGTGTCCCTGGTCTACCGGCGCGATCGTTTTGTGCGCGGACAGAATCCGATCCTGATCT
ATGGCTACGGCGCCTATGGCAGCAGCATGGATCCCGGCTTCAGCACCAGCCGCCTGAGTCTGCTCGACCGGGGCTTTGTG
TTTGCGCTGGCCCACGTCCGTGGCGGCGCCGATCTGGGACAGCAGTGGTATGAGGACGGTAAGCTACTGCATAAGCTGAA
CTCATTTTATGATTTTATCGATGTTACGCAGGGGCTGGTCCGTCAGGGGTATGCCGCCACCGATCAGGTCTATGCCATGG
GCGGCAGCGCCGGTGGGCTGCTGGTGGGCGGAGTGCTTAATATGGCTCCCCAGCTTTACCGCGGCGCAGTCGCCCAGGTA
CCTTTCGTCGACGTCGTGACGACCATGCTGGACCCCTCGATCCCGCTGACGACCGGTGAGTATGATGAGTGGGGGAATCC
GGAGGATCCCGAATACTACCACTACATGCAGCGTTACAGCCCCTATGATGGGGTCCGGGCACAGGCCTACCCCCATCTGT
TGGTGACCACCGGACTCCATGACTCTCAGGTGCAATACTGGGAGCCAGCCAAGTGGGTGGCACGCCTGCGTGAGATGAAA
TGTGATGATAACCTGCTGCTGCTGCATACCGATATGGAGGCGGGGCACGGGGGAAAATCGGGGCGCTTTAAAGCCTATGA
AGATATTGCGTTGGAATATGCGTTTATTTTAACGCTGTCTGGCGTAACACAATAG

Upstream 100 bases:

>100_bases
CTTACCAGGCATACGACGGTATTTTTGCATTTTCACCGCCTGCGGATTGTGTCACCCTGTTATAAGATGGCTTGTGTGAT
GAATCCGTTAGGCATTAAGA

Downstream 100 bases:

>100_bases
ACCCGCTTGGGTGAGCTTTAGCAAGGAGTCGTATGCCAATACTGCATTTACACCAGCGCGATATGTACTATGAGGACCAC
GGCAGCGGCTTTCCGCTGGT

Product: protease 2

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MKKAPKAAKHPYEIVMHGDRRVDDYYWLRDDTRSDPQVLAYLNAENAYSERCLAPQSALRSALLAEMVARIPQQDASVPY
VRNGYRYQHRYRPAAEYAEYWRQPESACPENETAWQRLLDTNQRAEGHDFYALGALEVSPDNRLLAISEDTVSRRQYTLR
VKSLMDDIWLEESIEGCDGHIEWCNDSRAFYYIRLDPQTLLPYQIYRHRLGTPCSQDCLIYQELDDAFYLGLEKSLSQRY
VMIHISSTTTSEVLLLDADDPEARAHCFQPRRRDHEYSLEHYDSRFYIRSNREGQNFALYCGPDGDVLSWQTLVPPRDAV
MLEDFCLFQEWLVVEERTHGLTTLRQIRRDDGEERLIHFDDPTYVTWLGYNPQPEIAKLRYGYASMTTPGSVYELDLNSG
ERRLLKQQSVAEFSAQDYASERIWLRARDGVDVPVSLVYRRDRFVRGQNPILIYGYGAYGSSMDPGFSTSRLSLLDRGFV
FALAHVRGGADLGQQWYEDGKLLHKLNSFYDFIDVTQGLVRQGYAATDQVYAMGGSAGGLLVGGVLNMAPQLYRGAVAQV
PFVDVVTTMLDPSIPLTTGEYDEWGNPEDPEYYHYMQRYSPYDGVRAQAYPHLLVTTGLHDSQVQYWEPAKWVARLREMK
CDDNLLLLHTDMEAGHGGKSGRFKAYEDIALEYAFILTLSGVTQ

Sequences:

>Translated_684_residues
MKKAPKAAKHPYEIVMHGDRRVDDYYWLRDDTRSDPQVLAYLNAENAYSERCLAPQSALRSALLAEMVARIPQQDASVPY
VRNGYRYQHRYRPAAEYAEYWRQPESACPENETAWQRLLDTNQRAEGHDFYALGALEVSPDNRLLAISEDTVSRRQYTLR
VKSLMDDIWLEESIEGCDGHIEWCNDSRAFYYIRLDPQTLLPYQIYRHRLGTPCSQDCLIYQELDDAFYLGLEKSLSQRY
VMIHISSTTTSEVLLLDADDPEARAHCFQPRRRDHEYSLEHYDSRFYIRSNREGQNFALYCGPDGDVLSWQTLVPPRDAV
MLEDFCLFQEWLVVEERTHGLTTLRQIRRDDGEERLIHFDDPTYVTWLGYNPQPEIAKLRYGYASMTTPGSVYELDLNSG
ERRLLKQQSVAEFSAQDYASERIWLRARDGVDVPVSLVYRRDRFVRGQNPILIYGYGAYGSSMDPGFSTSRLSLLDRGFV
FALAHVRGGADLGQQWYEDGKLLHKLNSFYDFIDVTQGLVRQGYAATDQVYAMGGSAGGLLVGGVLNMAPQLYRGAVAQV
PFVDVVTTMLDPSIPLTTGEYDEWGNPEDPEYYHYMQRYSPYDGVRAQAYPHLLVTTGLHDSQVQYWEPAKWVARLREMK
CDDNLLLLHTDMEAGHGGKSGRFKAYEDIALEYAFILTLSGVTQ
>Mature_684_residues
MKKAPKAAKHPYEIVMHGDRRVDDYYWLRDDTRSDPQVLAYLNAENAYSERCLAPQSALRSALLAEMVARIPQQDASVPY
VRNGYRYQHRYRPAAEYAEYWRQPESACPENETAWQRLLDTNQRAEGHDFYALGALEVSPDNRLLAISEDTVSRRQYTLR
VKSLMDDIWLEESIEGCDGHIEWCNDSRAFYYIRLDPQTLLPYQIYRHRLGTPCSQDCLIYQELDDAFYLGLEKSLSQRY
VMIHISSTTTSEVLLLDADDPEARAHCFQPRRRDHEYSLEHYDSRFYIRSNREGQNFALYCGPDGDVLSWQTLVPPRDAV
MLEDFCLFQEWLVVEERTHGLTTLRQIRRDDGEERLIHFDDPTYVTWLGYNPQPEIAKLRYGYASMTTPGSVYELDLNSG
ERRLLKQQSVAEFSAQDYASERIWLRARDGVDVPVSLVYRRDRFVRGQNPILIYGYGAYGSSMDPGFSTSRLSLLDRGFV
FALAHVRGGADLGQQWYEDGKLLHKLNSFYDFIDVTQGLVRQGYAATDQVYAMGGSAGGLLVGGVLNMAPQLYRGAVAQV
PFVDVVTTMLDPSIPLTTGEYDEWGNPEDPEYYHYMQRYSPYDGVRAQAYPHLLVTTGLHDSQVQYWEPAKWVARLREMK
CDDNLLLLHTDMEAGHGGKSGRFKAYEDIALEYAFILTLSGVTQ

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=700, Percent_Identity=25.4285714285714, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI284172420, Length=514, Percent_Identity=26.8482490272374, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI284172413, Length=514, Percent_Identity=26.8482490272374, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI70778815, Length=514, Percent_Identity=26.8482490272374, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI284172438, Length=514, Percent_Identity=26.8482490272374, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI284172431, Length=514, Percent_Identity=26.8482490272374, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI108860686, Length=421, Percent_Identity=28.0285035629454, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI108860692, Length=415, Percent_Identity=28.6746987951807, Blast_Score=149, Evalue=7e-36,
Organism=Escherichia coli, GI1788150, Length=679, Percent_Identity=59.499263622975, Blast_Score=867, Evalue=0.0,
Organism=Drosophila melanogaster, GI221510989, Length=710, Percent_Identity=25.2112676056338, Blast_Score=182, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24583414, Length=699, Percent_Identity=25.6080114449213, Blast_Score=175, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78692; Mature: 78692

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAPKAAKHPYEIVMHGDRRVDDYYWLRDDTRSDPQVLAYLNAENAYSERCLAPQSALR
CCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHCCHHHHHH
SALLAEMVARIPQQDASVPYVRNGYRYQHRYRPAAEYAEYWRQPESACPENETAWQRLLD
HHHHHHHHHHCCCCCCCCCCHHCCCEEHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHC
TNQRAEGHDFYALGALEVSPDNRLLAISEDTVSRRQYTLRVKSLMDDIWLEESIEGCDGH
CCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
IEWCNDSRAFYYIRLDPQTLLPYQIYRHRLGTPCSQDCLIYQELDDAFYLGLEKSLSQRY
EEEECCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEHHCCHHHHHHHHHCCCCE
VMIHISSTTTSEVLLLDADDPEARAHCFQPRRRDHEYSLEHYDSRFYIRSNREGQNFALY
EEEEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCCEEEEE
CGPDGDVLSWQTLVPPRDAVMLEDFCLFQEWLVVEERTHGLTTLRQIRRDDGEERLIHFD
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEC
DPTYVTWLGYNPQPEIAKLRYGYASMTTPGSVYELDLNSGERRLLKQQSVAEFSAQDYAS
CCCEEEEECCCCCCCHHHEEECCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCC
ERIWLRARDGVDVPVSLVYRRDRFVRGQNPILIYGYGAYGSSMDPGFSTSRLSLLDRGFV
CEEEEEECCCCCCCHHEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCHH
FALAHVRGGADLGQQWYEDGKLLHKLNSFYDFIDVTQGLVRQGYAATDQVYAMGGSAGGL
EEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
LVGGVLNMAPQLYRGAVAQVPFVDVVTTMLDPSIPLTTGEYDEWGNPEDPEYYHYMQRYS
HHHHHHHHHHHHHHCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
PYDGVRAQAYPHLLVTTGLHDSQVQYWEPAKWVARLREMKCDDNLLLLHTDMEAGHGGKS
CCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
GRFKAYEDIALEYAFILTLSGVTQ
CCCCHHHHHHHHEEEEEEECCCCC
>Mature Secondary Structure
MKKAPKAAKHPYEIVMHGDRRVDDYYWLRDDTRSDPQVLAYLNAENAYSERCLAPQSALR
CCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHCCHHHHHH
SALLAEMVARIPQQDASVPYVRNGYRYQHRYRPAAEYAEYWRQPESACPENETAWQRLLD
HHHHHHHHHHCCCCCCCCCCHHCCCEEHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHC
TNQRAEGHDFYALGALEVSPDNRLLAISEDTVSRRQYTLRVKSLMDDIWLEESIEGCDGH
CCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
IEWCNDSRAFYYIRLDPQTLLPYQIYRHRLGTPCSQDCLIYQELDDAFYLGLEKSLSQRY
EEEECCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEHHCCHHHHHHHHHCCCCE
VMIHISSTTTSEVLLLDADDPEARAHCFQPRRRDHEYSLEHYDSRFYIRSNREGQNFALY
EEEEEECCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCCEEEEE
CGPDGDVLSWQTLVPPRDAVMLEDFCLFQEWLVVEERTHGLTTLRQIRRDDGEERLIHFD
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEC
DPTYVTWLGYNPQPEIAKLRYGYASMTTPGSVYELDLNSGERRLLKQQSVAEFSAQDYAS
CCCEEEEECCCCCCCHHHEEECCEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCC
ERIWLRARDGVDVPVSLVYRRDRFVRGQNPILIYGYGAYGSSMDPGFSTSRLSLLDRGFV
CEEEEEECCCCCCCHHEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCHH
FALAHVRGGADLGQQWYEDGKLLHKLNSFYDFIDVTQGLVRQGYAATDQVYAMGGSAGGL
EEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCH
LVGGVLNMAPQLYRGAVAQVPFVDVVTTMLDPSIPLTTGEYDEWGNPEDPEYYHYMQRYS
HHHHHHHHHHHHHHCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
PYDGVRAQAYPHLLVTTGLHDSQVQYWEPAKWVARLREMKCDDNLLLLHTDMEAGHGGKS
CCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
GRFKAYEDIALEYAFILTLSGVTQ
CCCCHHHHHHHHEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]