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The map label for this gene is sapB [H]

Identifier: 238919725

GI number: 238919725

Start: 1766869

End: 1767834

Strand: Reverse

Name: sapB [H]

Synonym: NT01EI_1828

Alternate gene names: 238919725

Gene position: 1767834-1766869 (Counterclockwise)

Preceding gene: 238919726

Following gene: 238919724

Centisome position: 46.37

GC content: 62.22

Gene sequence:

>966_bases
ATGATTATTTTTACCCTGCGGCGTCTGCTGCTGCTGCTGGTCACACTGTTTTTCCTGACCCTCGTCAGCTTCAGCCTGCT
CTACTTTACGCCCCATGCCCCGCTTTCCGGAGCATCGCTCACCGACGCCTACCGTTTTTACCTGCACAGCCTGCTGCAGG
GCGACTTTGGCGTTTCCAGCATCAACGGGCAGGCCATCGTCGGGCAACTGCGGGAGGTGGTCCCCGCGACCCTGGAGCTG
TGTATCCTGGGTTTTCTGCTGGCGCTGTTCTGCGGCATCCCTATGGGCATTGCCGCCGGGATGATGCGCGGACGCTGGCC
GGACGGTGCCATCAGCACCCTGGCACTGCTCGGCTACTCCATGCCGGTATTCTGGCTGGCGCTGCTGCTGATGCTGTTTT
TTTCCCTGCACCTGGGCTGGCTGCCGGTCTCCGGGCGCTATGACCTGCTCTACCCGGTACCCAATATCAGCGGCTTCGCC
CTGGTGGATGCCTGGCTCTCCGAGGCCCCCTACCGCCATCAGATGCTGCTCAGCGTGCTGCGCCACCTGGTGCTGCCGGT
CAGCGTGCTGGCGCTGGTGCCAATGACCGAAGTCATCCGCCTGATGCGCCTCAGCACCGACGGCGTGGTTAGCCAAAACT
ACATCAAGGCGGCGGCGACCCGTGGCCTGTCGCGGCGGACCATTGTCCGCCGCCACGTACTGCACAACGCCCTGCCACCG
ATCATTCCCCAACTGGGTCTACAGTTTTCCACCATGCTGACCCTGGCGATGATAACCGAGGTGGTGTTCAGCTGGCCGGG
ACTGGGGCGCTGGCTGATCAACGCCATCCGTCAGCAGGACTTTGCTGCCATCTCGGCCGGCGTCATGGTGGTCGGTACGC
TGGTTCTGGTGGTCAATGTCCTGTGCGATATCATCGGCGCCGTCACCAGCCCGCTGAAACATAAGGAGTGGTATGCACTT
CGATAA

Upstream 100 bases:

>100_bases
ACATCAAAGGACTGGTGCTCAGTCCATTCGGCAACGCCTCGTTCGCAGGGGTATACCGTGATATACCGAGCCCGACGCCC
GCGCCGGACAAGGAGAAACC

Downstream 100 bases:

>100_bases
CCTCTACCGCGAGAAAAAGGTCCCCACTCCGCTACGACAGACCTGGTACCACTTTCACGCCGACTCGCTGGCCATGATCG
GCCTGTACGGCGTCGCCGCG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIIFTLRRLLLLLVTLFFLTLVSFSLLYFTPHAPLSGASLTDAYRFYLHSLLQGDFGVSSINGQAIVGQLREVVPATLEL
CILGFLLALFCGIPMGIAAGMMRGRWPDGAISTLALLGYSMPVFWLALLLMLFFSLHLGWLPVSGRYDLLYPVPNISGFA
LVDAWLSEAPYRHQMLLSVLRHLVLPVSVLALVPMTEVIRLMRLSTDGVVSQNYIKAAATRGLSRRTIVRRHVLHNALPP
IIPQLGLQFSTMLTLAMITEVVFSWPGLGRWLINAIRQQDFAAISAGVMVVGTLVLVVNVLCDIIGAVTSPLKHKEWYAL
R

Sequences:

>Translated_321_residues
MIIFTLRRLLLLLVTLFFLTLVSFSLLYFTPHAPLSGASLTDAYRFYLHSLLQGDFGVSSINGQAIVGQLREVVPATLEL
CILGFLLALFCGIPMGIAAGMMRGRWPDGAISTLALLGYSMPVFWLALLLMLFFSLHLGWLPVSGRYDLLYPVPNISGFA
LVDAWLSEAPYRHQMLLSVLRHLVLPVSVLALVPMTEVIRLMRLSTDGVVSQNYIKAAATRGLSRRTIVRRHVLHNALPP
IIPQLGLQFSTMLTLAMITEVVFSWPGLGRWLINAIRQQDFAAISAGVMVVGTLVLVVNVLCDIIGAVTSPLKHKEWYAL
R
>Mature_321_residues
MIIFTLRRLLLLLVTLFFLTLVSFSLLYFTPHAPLSGASLTDAYRFYLHSLLQGDFGVSSINGQAIVGQLREVVPATLEL
CILGFLLALFCGIPMGIAAGMMRGRWPDGAISTLALLGYSMPVFWLALLLMLFFSLHLGWLPVSGRYDLLYPVPNISGFA
LVDAWLSEAPYRHQMLLSVLRHLVLPVSVLALVPMTEVIRLMRLSTDGVVSQNYIKAAATRGLSRRTIVRRHVLHNALPP
IIPQLGLQFSTMLTLAMITEVVFSWPGLGRWLINAIRQQDFAAISAGVMVVGTLVLVVNVLCDIIGAVTSPLKHKEWYAL
R

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=321, Percent_Identity=71.3395638629283, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1789965, Length=347, Percent_Identity=33.4293948126801, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1787053, Length=337, Percent_Identity=28.486646884273, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1789888, Length=268, Percent_Identity=31.7164179104478, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787761, Length=249, Percent_Identity=39.7590361445783, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787497, Length=331, Percent_Identity=27.7945619335347, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788504, Length=258, Percent_Identity=25.968992248062, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35496; Mature: 35496

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFTLRRLLLLLVTLFFLTLVSFSLLYFTPHAPLSGASLTDAYRFYLHSLLQGDFGVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
INGQAIVGQLREVVPATLELCILGFLLALFCGIPMGIAAGMMRGRWPDGAISTLALLGYS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCC
MPVFWLALLLMLFFSLHLGWLPVSGRYDLLYPVPNISGFALVDAWLSEAPYRHQMLLSVL
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHH
RHLVLPVSVLALVPMTEVIRLMRLSTDGVVSQNYIKAAATRGLSRRTIVRRHVLHNALPP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
IIPQLGLQFSTMLTLAMITEVVFSWPGLGRWLINAIRQQDFAAISAGVMVVGTLVLVVNV
HHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCDIIGAVTSPLKHKEWYALR
HHHHHHHHHCCHHCCCCCCCC
>Mature Secondary Structure
MIIFTLRRLLLLLVTLFFLTLVSFSLLYFTPHAPLSGASLTDAYRFYLHSLLQGDFGVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
INGQAIVGQLREVVPATLELCILGFLLALFCGIPMGIAAGMMRGRWPDGAISTLALLGYS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCC
MPVFWLALLLMLFFSLHLGWLPVSGRYDLLYPVPNISGFALVDAWLSEAPYRHQMLLSVL
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHH
RHLVLPVSVLALVPMTEVIRLMRLSTDGVVSQNYIKAAATRGLSRRTIVRRHVLHNALPP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
IIPQLGLQFSTMLTLAMITEVVFSWPGLGRWLINAIRQQDFAAISAGVMVVGTLVLVVNV
HHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCDIIGAVTSPLKHKEWYALR
HHHHHHHHHCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]