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The map label for this gene is sapC [H]

Identifier: 238919724

GI number: 238919724

Start: 1765992

End: 1766882

Strand: Reverse

Name: sapC [H]

Synonym: NT01EI_1827

Alternate gene names: 238919724

Gene position: 1766882-1765992 (Counterclockwise)

Preceding gene: 238919725

Following gene: 238919723

Centisome position: 46.35

GC content: 64.2

Gene sequence:

>891_bases
ATGCACTTCGATAACCTCTACCGCGAGAAAAAGGTCCCCACTCCGCTACGACAGACCTGGTACCACTTTCACGCCGACTC
GCTGGCCATGATCGGCCTGTACGGCGTCGCCGCGCTGCTGCTGCTGTGCCTGTTTGGCAGCCTGCTGGCGCCCTATGGGC
TGGATCAGCAGTTTCTCGGCTACCAGCTGCTGCCCCCCTCCTGGTCACGCTACGGCAACGTCGCCTTCTTCCTCGGTACC
GACGACCTGGGCCGCGATCTGCTCAGTCGTCTGCTGTGCGGGGCTGCGCCGACCTTTGGCGCAGCGCTGACCGTCACCAT
CGCCGCCAGCCTGTGCGGCGTCCTGATCGGGGTGCTGGCCGGTATCACACACGGGCTGCGTTCGGCGATCCTTAACCATA
TTCTCGATACCCTGCTGGCGATCCCGTCGCTGCTGCTGGCGATCATCGTGGTGGCCTTTATCGGACCGCGTCTGGAGCAC
GCCATGCTGGCGGTATGGATGGCGCTGCTACCGCGTATCGTCCGCGCGGTCTACAGCGCGGTACATGAGGAGCTGGAGAA
AGAGTTCGTGGTCGCGGCGCGGCTGGACGGCGCCTCGACCTGGTTTATTCTGTGGGACGCCGTGATGCCCAATATCGCCG
GGGTACTGGTTTCCGAATTCACCCGCGCCCTCTCCATGGCGATCATCGATATTGCCGCGCTCGGCTTTCTCGATCTCGGG
GCCCAGCTGCCGTCACCGGAATGGGGCGCCATGCTGGGGGACTCGCTGGAGCTGCTGTATGTGGCCCCCTGGAGCGTGAT
GCTGCCGGGCGGCGCCATTATGATCAGCGTGCTGTTGGTCAACCTGCTGGGCGACGGGCTGCGTCGTGCCGTCAACGCCG
GGGTAAAATAA

Upstream 100 bases:

>100_bases
TCGGCCGGCGTCATGGTGGTCGGTACGCTGGTTCTGGTGGTCAATGTCCTGTGCGATATCATCGGCGCCGTCACCAGCCC
GCTGAAACATAAGGAGTGGT

Downstream 100 bases:

>100_bases
TGCCGCTACTCGATATCCGTAACCTGACCATTGAGTTTATGACACCTGGGGGCCCGGTCAAGGCCGTCGATCGTGTCAGC
CTGACCCTCAGCGAAGGTGA

Product: peptide transport system permease protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MHFDNLYREKKVPTPLRQTWYHFHADSLAMIGLYGVAALLLLCLFGSLLAPYGLDQQFLGYQLLPPSWSRYGNVAFFLGT
DDLGRDLLSRLLCGAAPTFGAALTVTIAASLCGVLIGVLAGITHGLRSAILNHILDTLLAIPSLLLAIIVVAFIGPRLEH
AMLAVWMALLPRIVRAVYSAVHEELEKEFVVAARLDGASTWFILWDAVMPNIAGVLVSEFTRALSMAIIDIAALGFLDLG
AQLPSPEWGAMLGDSLELLYVAPWSVMLPGGAIMISVLLVNLLGDGLRRAVNAGVK

Sequences:

>Translated_296_residues
MHFDNLYREKKVPTPLRQTWYHFHADSLAMIGLYGVAALLLLCLFGSLLAPYGLDQQFLGYQLLPPSWSRYGNVAFFLGT
DDLGRDLLSRLLCGAAPTFGAALTVTIAASLCGVLIGVLAGITHGLRSAILNHILDTLLAIPSLLLAIIVVAFIGPRLEH
AMLAVWMALLPRIVRAVYSAVHEELEKEFVVAARLDGASTWFILWDAVMPNIAGVLVSEFTRALSMAIIDIAALGFLDLG
AQLPSPEWGAMLGDSLELLYVAPWSVMLPGGAIMISVLLVNLLGDGLRRAVNAGVK
>Mature_296_residues
MHFDNLYREKKVPTPLRQTWYHFHADSLAMIGLYGVAALLLLCLFGSLLAPYGLDQQFLGYQLLPPSWSRYGNVAFFLGT
DDLGRDLLSRLLCGAAPTFGAALTVTIAASLCGVLIGVLAGITHGLRSAILNHILDTLLAIPSLLLAIIVVAFIGPRLEH
AMLAVWMALLPRIVRAVYSAVHEELEKEFVVAARLDGASTWFILWDAVMPNIAGVLVSEFTRALSMAIIDIAALGFLDLG
AQLPSPEWGAMLGDSLELLYVAPWSVMLPGGAIMISVLLVNLLGDGLRRAVNAGVK

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=75, Blast_Score=453, Evalue=1e-129,
Organism=Escherichia coli, GI1789964, Length=294, Percent_Identity=40.4761904761905, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1787054, Length=291, Percent_Identity=34.3642611683849, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1787760, Length=290, Percent_Identity=33.448275862069, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789889, Length=238, Percent_Identity=29.4117647058824, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787498, Length=216, Percent_Identity=31.0185185185185, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31901; Mature: 31901

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFDNLYREKKVPTPLRQTWYHFHADSLAMIGLYGVAALLLLCLFGSLLAPYGLDQQFLG
CCCHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
YQLLPPSWSRYGNVAFFLGTDDLGRDLLSRLLCGAAPTFGAALTVTIAASLCGVLIGVLA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GITHGLRSAILNHILDTLLAIPSLLLAIIVVAFIGPRLEHAMLAVWMALLPRIVRAVYSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
VHEELEKEFVVAARLDGASTWFILWDAVMPNIAGVLVSEFTRALSMAIIDIAALGFLDLG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDSLELLYVAPWSVMLPGGAIMISVLLVNLLGDGLRRAVNAGVK
CCCCCCCHHHHHCCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHFDNLYREKKVPTPLRQTWYHFHADSLAMIGLYGVAALLLLCLFGSLLAPYGLDQQFLG
CCCHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
YQLLPPSWSRYGNVAFFLGTDDLGRDLLSRLLCGAAPTFGAALTVTIAASLCGVLIGVLA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GITHGLRSAILNHILDTLLAIPSLLLAIIVVAFIGPRLEHAMLAVWMALLPRIVRAVYSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
VHEELEKEFVVAARLDGASTWFILWDAVMPNIAGVLVSEFTRALSMAIIDIAALGFLDLG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDSLELLYVAPWSVMLPGGAIMISVLLVNLLGDGLRRAVNAGVK
CCCCCCCHHHHHCCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]