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The map label for this gene is sapD [H]

Identifier: 238919723

GI number: 238919723

Start: 1764997

End: 1765992

Strand: Reverse

Name: sapD [H]

Synonym: NT01EI_1826

Alternate gene names: 238919723

Gene position: 1765992-1764997 (Counterclockwise)

Preceding gene: 238919724

Following gene: 238919722

Centisome position: 46.32

GC content: 62.75

Gene sequence:

>996_bases
ATGCCGCTACTCGATATCCGTAACCTGACCATTGAGTTTATGACACCTGGGGGCCCGGTCAAGGCCGTCGATCGTGTCAG
CCTGACCCTCAGCGAAGGTGAGATCCGTGGCCTGGTCGGTGAGTCTGGCTCTGGCAAAAGCCTGATCGCCAAGGCCATCT
GCGGGGTGACCAAGGACAACTGGCGGGTAACCGCCGACCGGATGCGCTTTGATGACATCGATCTGCTGCGCCTGTCGCCG
CGTCAGCGACGCCGACTGGTCGGCCACAACGTCTCGATGATTTTCCAGGAGCCGCAGTCCTGCCTCGACCCCTCCGAACG
CATTGGCCGCCAGCTGATCCAGGCGATCCCCGGCTGGACCTATAAAGGCCGCTGGTGGCAACGCTTTCACTGGCGCCGCC
GCCGCGCCATTGAGCTGCTGCACCGCGTCGGTATCAAAGATCACCGCGATGCCATGCGCAGCCTGCCCTACGAGCTGACG
GAGGGAGAGTGCCAGAAGGTGATGATCGCCATCGCCCTGGCTAATCAGCCGCGCCTGCTGATCGCCGATGAACCCACCAA
CGCCATGGAGCCGACCACCCAGGCGCAGATCTTCCGCCTGCTGGCGCGCATGAACCAGAACAACAACACCACCATTCTGC
TGATCAGCCACGATATGCAGATGATGAGTAAGTGGGCCGACCGCATTAACGTCATGTACTGCGGGCAGACGGTGGAGAGC
GCCAGCTGTGAGGAGATCCTCCGCGCGCCGCACCACCCCTATACCCAGGCTCTGCTCCGGGCGATGCCCGACTTTGGCCG
GTCGCTGCCGCCCAAGAGCCGCCTGAACACCCTGCCCGGTGCCATTCCGTCGCTGGAGCATCTGCCGATCGGCTGCCGCC
TGGGGCCACGCTGTCCCTACGCCCAGAAAAAGTGTATTCAGACCCCCACCCTGCGCAGTGTGAAAAACCACAGTTTTGCC
TGCCATTTCCCGCTGAACATGGAGGAGGCCCAGTGA

Upstream 100 bases:

>100_bases
GGAGCGTGATGCTGCCGGGCGGCGCCATTATGATCAGCGTGCTGTTGGTCAACCTGCTGGGCGACGGGCTGCGTCGTGCC
GTCAACGCCGGGGTAAAATA

Downstream 100 bases:

>100_bases
TGAAAACTCTGCTGGAGGTCCACGGCCTGGAAAAAACCTTTCGCTACCGCACCGGCTGGTTTCGCCGCCAGCGGGTCGAG
GCGGTCAAACCCGTCAGCTT

Product: peptide transport system ATP-binding protein SapD

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MPLLDIRNLTIEFMTPGGPVKAVDRVSLTLSEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSP
RQRRRLVGHNVSMIFQEPQSCLDPSERIGRQLIQAIPGWTYKGRWWQRFHWRRRRAIELLHRVGIKDHRDAMRSLPYELT
EGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARMNQNNNTTILLISHDMQMMSKWADRINVMYCGQTVES
ASCEEILRAPHHPYTQALLRAMPDFGRSLPPKSRLNTLPGAIPSLEHLPIGCRLGPRCPYAQKKCIQTPTLRSVKNHSFA
CHFPLNMEEAQ

Sequences:

>Translated_331_residues
MPLLDIRNLTIEFMTPGGPVKAVDRVSLTLSEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSP
RQRRRLVGHNVSMIFQEPQSCLDPSERIGRQLIQAIPGWTYKGRWWQRFHWRRRRAIELLHRVGIKDHRDAMRSLPYELT
EGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARMNQNNNTTILLISHDMQMMSKWADRINVMYCGQTVES
ASCEEILRAPHHPYTQALLRAMPDFGRSLPPKSRLNTLPGAIPSLEHLPIGCRLGPRCPYAQKKCIQTPTLRSVKNHSFA
CHFPLNMEEAQ
>Mature_330_residues
PLLDIRNLTIEFMTPGGPVKAVDRVSLTLSEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLRLSPR
QRRRLVGHNVSMIFQEPQSCLDPSERIGRQLIQAIPGWTYKGRWWQRFHWRRRRAIELLHRVGIKDHRDAMRSLPYELTE
GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARMNQNNNTTILLISHDMQMMSKWADRINVMYCGQTVESA
SCEEILRAPHHPYTQALLRAMPDFGRSLPPKSRLNTLPGAIPSLEHLPIGCRLGPRCPYAQKKCIQTPTLRSVKNHSFAC
HFPLNMEEAQ

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=329, Percent_Identity=83.5866261398176, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=43.9024390243902, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=39.3292682926829, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI48994883, Length=310, Percent_Identity=36.7741935483871, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1787500, Length=329, Percent_Identity=35.258358662614, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI145693107, Length=331, Percent_Identity=34.441087613293, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1788506, Length=263, Percent_Identity=36.8821292775665, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789962, Length=314, Percent_Identity=31.8471337579618, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787758, Length=287, Percent_Identity=34.1463414634146, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789890, Length=261, Percent_Identity=30.6513409961686, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI48994997, Length=267, Percent_Identity=32.2097378277154, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787547, Length=274, Percent_Identity=28.8321167883212, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786398, Length=262, Percent_Identity=30.5343511450382, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789891, Length=257, Percent_Identity=29.9610894941634, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789032, Length=241, Percent_Identity=28.6307053941909, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87081834, Length=231, Percent_Identity=30.3030303030303, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789873, Length=222, Percent_Identity=30.6306306306306, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788225, Length=260, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790525, Length=282, Percent_Identity=29.0780141843972, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788450, Length=251, Percent_Identity=26.6932270916335, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790162, Length=257, Percent_Identity=22.9571984435798, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787712, Length=255, Percent_Identity=26.2745098039216, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786345, Length=246, Percent_Identity=27.2357723577236, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787089, Length=231, Percent_Identity=29.004329004329, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082268, Length=248, Percent_Identity=27.8225806451613, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786703, Length=218, Percent_Identity=28.8990825688073, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789672, Length=245, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786872, Length=223, Percent_Identity=27.8026905829596, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787105, Length=241, Percent_Identity=28.6307053941909, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790544, Length=236, Percent_Identity=25.8474576271186, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994943, Length=248, Percent_Identity=25.4032258064516, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786253, Length=225, Percent_Identity=28, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788644, Length=129, Percent_Identity=30.2325581395349, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48995001, Length=250, Percent_Identity=27.6, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=259, Percent_Identity=22.3938223938224, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787792, Length=248, Percent_Identity=27.4193548387097, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082267, Length=242, Percent_Identity=23.1404958677686, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790739, Length=248, Percent_Identity=25.4032258064516, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790190, Length=252, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787112, Length=256, Percent_Identity=25.78125, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786319, Length=265, Percent_Identity=26.7924528301887, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37732; Mature: 37601

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRNLTIEFMTPGGPVKAVDRVSLTLSEGEIRGLVGESGSGKSLIAKAICGVTKDN
CCCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCC
WRVTADRMRFDDIDLLRLSPRQRRRLVGHNVSMIFQEPQSCLDPSERIGRQLIQAIPGWT
CEEEHHHCCCCCCCEEECCHHHHHHHHCCCHHHEEECCHHHCCHHHHHHHHHHHHCCCCC
YKGRWWQRFHWRRRRAIELLHRVGIKDHRDAMRSLPYELTEGECQKVMIAIALANQPRLL
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNAMEPTTQAQIFRLLARMNQNNNTTILLISHDMQMMSKWADRINVMYCGQTVES
EECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCEEEECCCCCCC
ASCEEILRAPHHPYTQALLRAMPDFGRSLPPKSRLNTLPGAIPSLEHLPIGCRLGPRCPY
CCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
AQKKCIQTPTLRSVKNHSFACHFPLNMEEAQ
HHHHHCCCCHHHHHCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
PLLDIRNLTIEFMTPGGPVKAVDRVSLTLSEGEIRGLVGESGSGKSLIAKAICGVTKDN
CCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCC
WRVTADRMRFDDIDLLRLSPRQRRRLVGHNVSMIFQEPQSCLDPSERIGRQLIQAIPGWT
CEEEHHHCCCCCCCEEECCHHHHHHHHCCCHHHEEECCHHHCCHHHHHHHHHHHHCCCCC
YKGRWWQRFHWRRRRAIELLHRVGIKDHRDAMRSLPYELTEGECQKVMIAIALANQPRLL
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNAMEPTTQAQIFRLLARMNQNNNTTILLISHDMQMMSKWADRINVMYCGQTVES
EECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCEEEECCCCCCC
ASCEEILRAPHHPYTQALLRAMPDFGRSLPPKSRLNTLPGAIPSLEHLPIGCRLGPRCPY
CCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
AQKKCIQTPTLRSVKNHSFACHFPLNMEEAQ
HHHHHCCCCHHHHHCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]