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The map label for this gene is tcyB [H]

Identifier: 238919597

GI number: 238919597

Start: 1656239

End: 1656937

Strand: Reverse

Name: tcyB [H]

Synonym: NT01EI_1696

Alternate gene names: 238919597

Gene position: 1656937-1656239 (Counterclockwise)

Preceding gene: 238919598

Following gene: 238919593

Centisome position: 43.46

GC content: 61.66

Gene sequence:

>699_bases
ATGCCCCACTGGCTATCCCCCCTGATCGCTATCCTGCCGCAGCCCGACTGGCTGCAACCGGTCGCTGACGCCTTCTGGCC
TCTGCTCTCCGCCGCGCTGCGCTTCTCCCTACCGCTGGCGCTGCTCTCCTTCTGCGGCGGCCTGCTGGTGGGGCTGGCCA
CCGCGTTAATCCGCCTGTACGCCATTCGGCCGCTGAGGCTCTGTGCCGATTTCTATATCTGGGTTTTTCGTGGAACCCCG
CTGCTGGTACAACTGTTCCTGATCTTTTATGGTCTGCCGAGCGCCGGGATCACGCTGGATGCCTTTCCCGCCGCGCTGAT
CGGTTTTACCCTCAACGTCGGCGCCTACAGCTCAGAGATCGTCCGCGGCGCAATCCTGTCGGTCCCACAGGGCCAGTGGG
AGGCGGCCAGCGCTATCGGTATGAGCAGCAGCCAAGCGATGCGTCGGGTGATCCTGCCGCAATCGGCCTTTGTCAGCCTG
CCACCGCTCTCCAACGTATTTATCTCTCTGATAAAGGATACCTCCCTGGCCGCGGTGATCACCGTGCCGGAGATGTTTCT
CGCCGCCCAGCGCATTGTGGCGGTCAACTATGAACCGCTGATCATCTACAGTGAAACGGCACTGATCTACCTGGCCTTCA
GCACCCTGCTCGGCAAGCTGCAGCTACGCCTAGAACGCTATTACCGTCGCTACGAGTGA

Upstream 100 bases:

>100_bases
TTCGGCAGCGACGTCTCACAATAATCGCCAATCGCCGCCGCGCATTTCCGGCGTTATCCCGCCGCACTGGCGGCGGGCGC
CCAGATATGGAGTCTCCACC

Downstream 100 bases:

>100_bases
GCTATCAACATAAAAAAAACCCGCAGGTAATTCCTGCGGGCTCAAATGCAATGAGAAACTCTATGTCGAAATTAATCAAC
AAAGAAACTCTATCATGGCA

Product: L-cystine transport system permease protein TcyB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MPHWLSPLIAILPQPDWLQPVADAFWPLLSAALRFSLPLALLSFCGGLLVGLATALIRLYAIRPLRLCADFYIWVFRGTP
LLVQLFLIFYGLPSAGITLDAFPAALIGFTLNVGAYSSEIVRGAILSVPQGQWEAASAIGMSSSQAMRRVILPQSAFVSL
PPLSNVFISLIKDTSLAAVITVPEMFLAAQRIVAVNYEPLIIYSETALIYLAFSTLLGKLQLRLERYYRRYE

Sequences:

>Translated_232_residues
MPHWLSPLIAILPQPDWLQPVADAFWPLLSAALRFSLPLALLSFCGGLLVGLATALIRLYAIRPLRLCADFYIWVFRGTP
LLVQLFLIFYGLPSAGITLDAFPAALIGFTLNVGAYSSEIVRGAILSVPQGQWEAASAIGMSSSQAMRRVILPQSAFVSL
PPLSNVFISLIKDTSLAAVITVPEMFLAAQRIVAVNYEPLIIYSETALIYLAFSTLLGKLQLRLERYYRRYE
>Mature_231_residues
PHWLSPLIAILPQPDWLQPVADAFWPLLSAALRFSLPLALLSFCGGLLVGLATALIRLYAIRPLRLCADFYIWVFRGTPL
LVQLFLIFYGLPSAGITLDAFPAALIGFTLNVGAYSSEIVRGAILSVPQGQWEAASAIGMSSSQAMRRVILPQSAFVSLP
PLSNVFISLIKDTSLAAVITVPEMFLAAQRIVAVNYEPLIIYSETALIYLAFSTLLGKLQLRLERYYRRYE

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=215, Percent_Identity=50.6976744186047, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI1787030, Length=221, Percent_Identity=38.9140271493213, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788645, Length=201, Percent_Identity=34.8258706467662, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787086, Length=213, Percent_Identity=34.2723004694836, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787087, Length=242, Percent_Identity=29.3388429752066, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788646, Length=204, Percent_Identity=32.3529411764706, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082239, Length=206, Percent_Identity=31.5533980582524, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1786873, Length=178, Percent_Identity=34.8314606741573, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786874, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI48994930, Length=117, Percent_Identity=34.1880341880342, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25591; Mature: 25460

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHWLSPLIAILPQPDWLQPVADAFWPLLSAALRFSLPLALLSFCGGLLVGLATALIRLY
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIRPLRLCADFYIWVFRGTPLLVQLFLIFYGLPSAGITLDAFPAALIGFTLNVGAYSSEI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
VRGAILSVPQGQWEAASAIGMSSSQAMRRVILPQSAFVSLPPLSNVFISLIKDTSLAAVI
HHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCHHHEECCCHHHHHHHHHHCCCHHEEH
TVPEMFLAAQRIVAVNYEPLIIYSETALIYLAFSTLLGKLQLRLERYYRRYE
HHHHHHHHHHHHHEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PHWLSPLIAILPQPDWLQPVADAFWPLLSAALRFSLPLALLSFCGGLLVGLATALIRLY
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIRPLRLCADFYIWVFRGTPLLVQLFLIFYGLPSAGITLDAFPAALIGFTLNVGAYSSEI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
VRGAILSVPQGQWEAASAIGMSSSQAMRRVILPQSAFVSLPPLSNVFISLIKDTSLAAVI
HHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCHHHEECCCHHHHHHHHHHCCCHHEEH
TVPEMFLAAQRIVAVNYEPLIIYSETALIYLAFSTLLGKLQLRLERYYRRYE
HHHHHHHHHHHHHEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]