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The map label for this gene is nudG [H]

Identifier: 238919556

GI number: 238919556

Start: 1614804

End: 1615232

Strand: Reverse

Name: nudG [H]

Synonym: NT01EI_1652

Alternate gene names: 238919556

Gene position: 1615232-1614804 (Counterclockwise)

Preceding gene: 238919557

Following gene: 238919550

Centisome position: 42.37

GC content: 67.13

Gene sequence:

>429_bases
ATGAGCGCGCAGGCAGCGGAAAAAATCCTGCATGTCGTCGCCGCCATCATTGAGCGGCGCGGTGCTATCCTGCTAGCTCA
GCGCGGCCAGGGGCAGGATCAGGCGGGGCTGTGGGAGTTTCCCGGTGGAAAGGTCGAGGCGGGAGAGAGCCAGCCTCAGG
CGCTGCAGCGTGAACTGGATGAAGAGCTGGGGCTACGCTGCCGGGTCAGCGACTACGTCGCCAGCAGCACACTGCACCTG
CCGGGTAAGCGCATCCACCTGCACGCCTGGCGGGTACAGCCGGAAGGGGGCGAACCTGAGGCGCGAGAGCACGCGGCGTT
GTGCTGGGTCGCCCCATGCCAGGCGCAGACATACGACCTGGCGCCGGCGGACAGGCCGCTGCTGCAGGCCTATCTGGATC
TGCTGGCGCGTTTTCACGCCGATGCCTGA

Upstream 100 bases:

>100_bases
CGCTGGCCCAGCGCTGTACCGATACCGGCATCGACTATGAGATCCGCGCCATGGAGAAACCCTCGGATCACGCCCCGATC
TGGGCCGAGTTCGCACTTTC

Downstream 100 bases:

>100_bases
GGCCATCGCGGAGAGAGTCTGGCGCGTTTACCCTTTCTTCAGCACCACCCAACGCAGGTTGTTGGTACTCAGCACCTGCG
GATTGGCCTGACACTGCAGC

Product: pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSAQAAEKILHVVAAIIERRGAILLAQRGQGQDQAGLWEFPGGKVEAGESQPQALQRELDEELGLRCRVSDYVASSTLHL
PGKRIHLHAWRVQPEGGEPEAREHAALCWVAPCQAQTYDLAPADRPLLQAYLDLLARFHADA

Sequences:

>Translated_142_residues
MSAQAAEKILHVVAAIIERRGAILLAQRGQGQDQAGLWEFPGGKVEAGESQPQALQRELDEELGLRCRVSDYVASSTLHL
PGKRIHLHAWRVQPEGGEPEAREHAALCWVAPCQAQTYDLAPADRPLLQAYLDLLARFHADA
>Mature_141_residues
SAQAAEKILHVVAAIIERRGAILLAQRGQGQDQAGLWEFPGGKVEAGESQPQALQRELDEELGLRCRVSDYVASSTLHLP
GKRIHLHAWRVQPEGGEPEAREHAALCWVAPCQAQTYDLAPADRPLLQAYLDLLARFHADA

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=134, Percent_Identity=58.2089552238806, Blast_Score=137, Evalue=3e-34,
Organism=Escherichia coli, GI1786288, Length=122, Percent_Identity=31.1475409836066, Blast_Score=63, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15593; Mature: 15462

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQAAEKILHVVAAIIERRGAILLAQRGQGQDQAGLWEFPGGKVEAGESQPQALQRELD
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCCCEECCCCCHHHHHHHHH
EELGLRCRVSDYVASSTLHLPGKRIHLHAWRVQPEGGEPEAREHAALCWVAPCQAQTYDL
HHHCCEEEEHHHHHCCEEECCCCEEEEEEEEECCCCCCCCCHHCEEEEEECCCCCCEECC
APADRPLLQAYLDLLARFHADA
CCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAQAAEKILHVVAAIIERRGAILLAQRGQGQDQAGLWEFPGGKVEAGESQPQALQRELD
CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCCCEECCCCCHHHHHHHHH
EELGLRCRVSDYVASSTLHLPGKRIHLHAWRVQPEGGEPEAREHAALCWVAPCQAQTYDL
HHHCCEEEEHHHHHCCEEECCCCEEEEEEEEECCCCCCCCCHHCEEEEEECCCCCCEECC
APADRPLLQAYLDLLARFHADA
CCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]