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The map label for this gene is argS

Identifier: 238919488

GI number: 238919488

Start: 1545740

End: 1547473

Strand: Reverse

Name: argS

Synonym: NT01EI_1584

Alternate gene names: 238919488

Gene position: 1547473-1545740 (Counterclockwise)

Preceding gene: 238919490

Following gene: 238919484

Centisome position: 40.59

GC content: 60.32

Gene sequence:

>1734_bases
GTGAATATTCAGGAAATTATTTCAGATAAAGTCACTCAGGCGCTGGTTGCTGCCGGTGCGCCAGCCGGCAGCGAGGCCTT
GGTCCGTCCCTCCGCGAAAGTCCAGTTTGGCGACTATCAGGCCAATGGCATTATGTCCGCGGCGAAAAAAATGGGCCTGC
CTCCGCGACAGCTCGCCGAACAGGTCGTGGCCAATCTGGCACTGGATGGGATCGCCAGCAAGGTAGAGATTGCCGGCCCG
GGCTTCATCAATATTTTCCTCGATGCCGCCTGGCTGGCCGCACAGGCCGACGCCGCGCTAGCCGATCCGCGCCTGGGCGT
GGCCCGTGTCGAGCCGCAGACTATCGTCGTTGACTACTCCGCGCCGAACGTCGCCAAAGAGATGCACGTCGGTCATCTGC
GCTCCACCATCATCGGCGACGCCGCCGTACGCACCCTGGAGTTCCTCGGCCACAACGTCATCCGCGCCAACCATGTCGGC
GACTGGGGCACCCAGTTCGGTATGTTGATCGCCTATCTGGAAAAGGTGCAGGGCAGCAGCGAAACCGGCGACATGGCGCT
GGCCGATCTGGAGGCCTTCTACCGCGAAGCCAAAAAGCACTACGATGAAGATGCGGCCTTTGCCGAACGCGCGCGCGGCT
ATGTGGTTAAACTGCAGGGCGGCGATGAATACTGCCGCGAAATGTGGCGCAAGCTGGTGGACATCACCATGCGTCAGAAC
CAGCGCAACTATGACCGTCTCAACGTGACCCTGACCGACGATGACGTCATGGGTGAGAGTCTGTACAACCCGATGCTGCC
GGGGATCGTCGCCGATCTGAAGGCCAAGGGACTGGCCACCGAAAGCGAAGGTGCCACCGTCGTCTTTCTGAACGAGTTCA
GGAACAAAGAGGGCGAGCCGATGGGGGTGATCGTCCAGAAGAAGGACGGCGGCTACCTGTACACCACCACCGATATCGCC
TGCGCCAAGTACCGTTATGAGACCCTTGGCGCCAACCGTATCCTGTACTACATCGACTCCCGCCAGCATCAGCACCTGAT
GCAGGCCTGGACCATCGTGCGTAAGGCCGGTTATGTGCCGGACTCCGTCAGCCTGGAGCACCACATGTTCGGCATGATGC
TGGGTAAAGACGGCAAGCCGTTCAAGACCCGTGCCGGTGGCACCATCAAGCTGGCCGATCTGCTGGATGAGGCCATCGAA
CGCGCCGCCAAGCTGATCGCCGCCAAGAACCCGGAGCTGAGCGGCGACGAACTGAAGGCGCTGGTGGAAGTGGTCGGTAT
CGGTGCGGTCAAGTATGCGGATCTCTCCAAAAACCGCACTACCGACTATATCTTTGACTGGGACAACATGCTGGCCTTTG
AGGGCAACACCGCCCCTTACATGCAGTATGCCTATACCCGCGTCGCCTCCATCTTCAAGCGTGCCGGCATTGATGAAAAT
ACCCTGCAGGGTGCCATTACGCTGACAGAAGAGCGTGAAAAGGCGCTGGCTACCCGCCTGATGCAGTTTGAGGAGACCAT
CCTGAGCGTCGCGCGTGAGGGGACTCCACACGTCATGTGCGCCTACCTGTACGAAGTCGCAGGCCTGTTCTCCAGCTTCT
ATGAGGCCTGCCCGATCCTCAACGCCGAGGAGGAGAGCGTGCGCGCCAGCCGTCTGAAGCTGGCCGCCCTGACAGCACGT
ACGCTGAAAACCGGCCTGGATACCCTGGGGATCAAGACGGTCGAGCGTATGTAA

Upstream 100 bases:

>100_bases
GTTTTCCGCCGGGTGAAATGCCCCGGCGGTCATGATTCGGTTTTCACATTCACGACGCCGGCGCCGCGTGCGTCCGGTGC
GAATAGCTTAAGGTAATCCC

Downstream 100 bases:

>100_bases
CGCCACTGCCGAACCACAACGCTCGCCACCGCCGACGGCGGTGGCTGACGATTGATAGCAAAAAGCCACCTGCCCCGCAG
GTGGCTTTTTTATGACCGCG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIQEIISDKVTQALVAAGAPAGSEALVRPSAKVQFGDYQANGIMSAAKKMGLPPRQLAEQVVANLALDGIASKVEIAGP
GFINIFLDAAWLAAQADAALADPRLGVARVEPQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKVQGSSETGDMALADLEAFYREAKKHYDEDAAFAERARGYVVKLQGGDEYCREMWRKLVDITMRQN
QRNYDRLNVTLTDDDVMGESLYNPMLPGIVADLKAKGLATESEGATVVFLNEFRNKEGEPMGVIVQKKDGGYLYTTTDIA
CAKYRYETLGANRILYYIDSRQHQHLMQAWTIVRKAGYVPDSVSLEHHMFGMMLGKDGKPFKTRAGGTIKLADLLDEAIE
RAAKLIAAKNPELSGDELKALVEVVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFKRAGIDEN
TLQGAITLTEEREKALATRLMQFEETILSVAREGTPHVMCAYLYEVAGLFSSFYEACPILNAEEESVRASRLKLAALTAR
TLKTGLDTLGIKTVERM

Sequences:

>Translated_577_residues
MNIQEIISDKVTQALVAAGAPAGSEALVRPSAKVQFGDYQANGIMSAAKKMGLPPRQLAEQVVANLALDGIASKVEIAGP
GFINIFLDAAWLAAQADAALADPRLGVARVEPQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKVQGSSETGDMALADLEAFYREAKKHYDEDAAFAERARGYVVKLQGGDEYCREMWRKLVDITMRQN
QRNYDRLNVTLTDDDVMGESLYNPMLPGIVADLKAKGLATESEGATVVFLNEFRNKEGEPMGVIVQKKDGGYLYTTTDIA
CAKYRYETLGANRILYYIDSRQHQHLMQAWTIVRKAGYVPDSVSLEHHMFGMMLGKDGKPFKTRAGGTIKLADLLDEAIE
RAAKLIAAKNPELSGDELKALVEVVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFKRAGIDEN
TLQGAITLTEEREKALATRLMQFEETILSVAREGTPHVMCAYLYEVAGLFSSFYEACPILNAEEESVRASRLKLAALTAR
TLKTGLDTLGIKTVERM
>Mature_577_residues
MNIQEIISDKVTQALVAAGAPAGSEALVRPSAKVQFGDYQANGIMSAAKKMGLPPRQLAEQVVANLALDGIASKVEIAGP
GFINIFLDAAWLAAQADAALADPRLGVARVEPQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHNVIRANHVG
DWGTQFGMLIAYLEKVQGSSETGDMALADLEAFYREAKKHYDEDAAFAERARGYVVKLQGGDEYCREMWRKLVDITMRQN
QRNYDRLNVTLTDDDVMGESLYNPMLPGIVADLKAKGLATESEGATVVFLNEFRNKEGEPMGVIVQKKDGGYLYTTTDIA
CAKYRYETLGANRILYYIDSRQHQHLMQAWTIVRKAGYVPDSVSLEHHMFGMMLGKDGKPFKTRAGGTIKLADLLDEAIE
RAAKLIAAKNPELSGDELKALVEVVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFKRAGIDEN
TLQGAITLTEEREKALATRLMQFEETILSVAREGTPHVMCAYLYEVAGLFSSFYEACPILNAEEESVRASRLKLAALTAR
TLKTGLDTLGIKTVERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=573, Percent_Identity=38.5689354275742, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI197100773, Length=482, Percent_Identity=30.9128630705394, Blast_Score=204, Evalue=2e-52,
Organism=Escherichia coli, GI1788184, Length=578, Percent_Identity=80.1038062283737, Blast_Score=958, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=563, Percent_Identity=37.8330373001776, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71985068, Length=540, Percent_Identity=37.7777777777778, Blast_Score=352, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17532153, Length=385, Percent_Identity=27.012987012987, Blast_Score=142, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320548, Length=543, Percent_Identity=31.8600368324125, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6321883, Length=549, Percent_Identity=28.5974499089253, Blast_Score=214, Evalue=3e-56,
Organism=Drosophila melanogaster, GI18859963, Length=564, Percent_Identity=37.2340425531915, Blast_Score=386, Evalue=1e-107,
Organism=Drosophila melanogaster, GI28571570, Length=478, Percent_Identity=29.2887029288703, Blast_Score=171, Evalue=9e-43,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_EDWI9 (C5B832)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933003.1
- ProteinModelPortal:   C5B832
- GeneID:   7961912
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1584
- OMA:   HMGFGTM
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63483; Mature: 63483

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQEIISDKVTQALVAAGAPAGSEALVRPSAKVQFGDYQANGIMSAAKKMGLPPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEECCCCCHHHHHHHHHCCCCHHHHHH
QVVANLALDGIASKVEIAGPGFINIFLDAAWLAAQADAALADPRLGVARVEPQTIVVDYS
HHHHHHHHHHHCCEEEECCCCEEEHHHHHHHHHHHCCHHHCCCCCCEEEECCCEEEEECC
APNVAKEMHVGHLRSTIIGDAAVRTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKVQGSS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
ETGDMALADLEAFYREAKKHYDEDAAFAERARGYVVKLQGGDEYCREMWRKLVDITMRQN
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCC
QRNYDRLNVTLTDDDVMGESLYNPMLPGIVADLKAKGLATESEGATVVFLNEFRNKEGEP
CCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCC
MGVIVQKKDGGYLYTTTDIACAKYRYETLGANRILYYIDSRQHQHLMQAWTIVRKAGYVP
EEEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
DSVSLEHHMFGMMLGKDGKPFKTRAGGTIKLADLLDEAIERAAKLIAAKNPELSGDELKA
CCCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LVEVVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFKRAGIDEN
HHHHHHCCCEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
TLQGAITLTEEREKALATRLMQFEETILSVAREGTPHVMCAYLYEVAGLFSSFYEACPIL
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NAEEESVRASRLKLAALTARTLKTGLDTLGIKTVERM
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHCC
>Mature Secondary Structure
MNIQEIISDKVTQALVAAGAPAGSEALVRPSAKVQFGDYQANGIMSAAKKMGLPPRQLAE
CCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCEEEECCCCCHHHHHHHHHCCCCHHHHHH
QVVANLALDGIASKVEIAGPGFINIFLDAAWLAAQADAALADPRLGVARVEPQTIVVDYS
HHHHHHHHHHHCCEEEECCCCEEEHHHHHHHHHHHCCHHHCCCCCCEEEECCCEEEEECC
APNVAKEMHVGHLRSTIIGDAAVRTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKVQGSS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCC
ETGDMALADLEAFYREAKKHYDEDAAFAERARGYVVKLQGGDEYCREMWRKLVDITMRQN
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCC
QRNYDRLNVTLTDDDVMGESLYNPMLPGIVADLKAKGLATESEGATVVFLNEFRNKEGEP
CCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCC
MGVIVQKKDGGYLYTTTDIACAKYRYETLGANRILYYIDSRQHQHLMQAWTIVRKAGYVP
EEEEEEECCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
DSVSLEHHMFGMMLGKDGKPFKTRAGGTIKLADLLDEAIERAAKLIAAKNPELSGDELKA
CCCCHHHHHHHHHCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LVEVVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVASIFKRAGIDEN
HHHHHHCCCEEEECCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
TLQGAITLTEEREKALATRLMQFEETILSVAREGTPHVMCAYLYEVAGLFSSFYEACPIL
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NAEEESVRASRLKLAALTARTLKTGLDTLGIKTVERM
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA