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The map label for this gene is 238919233

Identifier: 238919233

GI number: 238919233

Start: 1307096

End: 1308136

Strand: Direct

Name: 238919233

Synonym: NT01EI_1316

Alternate gene names: NA

Gene position: 1307096-1308136 (Clockwise)

Preceding gene: 238919232

Following gene: 238919234

Centisome position: 34.29

GC content: 37.37

Gene sequence:

>1041_bases
ATGAATAAAGTGTATATCGTTGCTGAAATTGGCTGTAACCATAATGGCGATCCTCTACTGGCTAAAAAAATGGTTGAGCA
GGCAAAAGCCGCTGGGGTGGATGCCGTAAAGTTTCAAACATTTAAAGCAGATTTGCTGATTTCAAAGTATGCACCAAAGG
CGGAGTATCAGATAACGCAAACTGGCTGCGAAGAGTCTCAGCTTGAGATGACACGCAAATTGGAGCTTGCATATGATGAC
TTTATTGGATTGTCACAATATGCAAAAAGCCTTGGCTTAGATGTTTTCTCTACCCCTTTTGATTTTGATTCAATCGATTT
TCTTGCTTCATTAAAACAACGCATATGGAAAATTCCATCTGGAGAGTTATTAAATCTTCCTTATCTTGAAAAAATAGCAA
GACTAGATATTACTGATAAGAAAATTATCATATCGACCGGAATGGCAACGCTAGATGAAATTAATATGGCATTGCATGTA
TTGCATAACAATGGTGTCAAAGCAAGTGATATTACCATTCTACACTGTAATACAGAATATCCTACACCCTATTCTGATGT
GAATCTTAATACGTTGTCTAGCTTTAAGAATATTTTTAAAGAATATCAGATTGGATTCTCCGATCACTCCCCTGGATATT
TTTCAGGGATTGCAGCTGTGCCTTATGGTATCTGTTTTATCGAGAAGCATTTTACTTTAAATAAAGAATTTCCCGGTCCA
GATCATAAAGCATCGGTGACTCCAGATGAATTGCGACTCTTATGTCAGGGGATTCGGGCTATTGAATTAGCATTAGGCAG
CTATGATAAAATTGTGACTAATTCTGAACGCAAGAATAAAATAGTTGCTCGAAAATCGATCATTGCCAAACAGAATATAA
AGCAAGGTGAGGTTTTTACTTTAGAGAATATTACAACCAAGCGTCCAGGTAATGGAATTAGTCCTATGCATTGGTATCAG
GTCTTAGGCAGCATTGCAGAGCGAGATTTTTGTGAAGATGAACTGATCTATTGCTCTAACTTGAGCATGCAGGAGCTATA
A

Upstream 100 bases:

>100_bases
AATGACTCAGTTATTGGCTCAGGCTCAGTGGTGATTAGAGATATTCCAGATAACGTTGTAGTTGCGGGCTCCCCGACGCG
TTTAATCAGAGAGAATCATG

Downstream 100 bases:

>100_bases
GATATATGAAAGTTGCCATCATTCCAGCTCGCTCTGGCTCAAAGGGATTGCGCAATAAAAACATTCTAATGTTAATGGAT
AAGCCATTAATTGCGTATAC

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNKVYIVAEIGCNHNGDPLLAKKMVEQAKAAGVDAVKFQTFKADLLISKYAPKAEYQITQTGCEESQLEMTRKLELAYDD
FIGLSQYAKSLGLDVFSTPFDFDSIDFLASLKQRIWKIPSGELLNLPYLEKIARLDITDKKIIISTGMATLDEINMALHV
LHNNGVKASDITILHCNTEYPTPYSDVNLNTLSSFKNIFKEYQIGFSDHSPGYFSGIAAVPYGICFIEKHFTLNKEFPGP
DHKASVTPDELRLLCQGIRAIELALGSYDKIVTNSERKNKIVARKSIIAKQNIKQGEVFTLENITTKRPGNGISPMHWYQ
VLGSIAERDFCEDELIYCSNLSMQEL

Sequences:

>Translated_346_residues
MNKVYIVAEIGCNHNGDPLLAKKMVEQAKAAGVDAVKFQTFKADLLISKYAPKAEYQITQTGCEESQLEMTRKLELAYDD
FIGLSQYAKSLGLDVFSTPFDFDSIDFLASLKQRIWKIPSGELLNLPYLEKIARLDITDKKIIISTGMATLDEINMALHV
LHNNGVKASDITILHCNTEYPTPYSDVNLNTLSSFKNIFKEYQIGFSDHSPGYFSGIAAVPYGICFIEKHFTLNKEFPGP
DHKASVTPDELRLLCQGIRAIELALGSYDKIVTNSERKNKIVARKSIIAKQNIKQGEVFTLENITTKRPGNGISPMHWYQ
VLGSIAERDFCEDELIYCSNLSMQEL
>Mature_346_residues
MNKVYIVAEIGCNHNGDPLLAKKMVEQAKAAGVDAVKFQTFKADLLISKYAPKAEYQITQTGCEESQLEMTRKLELAYDD
FIGLSQYAKSLGLDVFSTPFDFDSIDFLASLKQRIWKIPSGELLNLPYLEKIARLDITDKKIIISTGMATLDEINMALHV
LHNNGVKASDITILHCNTEYPTPYSDVNLNTLSSFKNIFKEYQIGFSDHSPGYFSGIAAVPYGICFIEKHFTLNKEFPGP
DHKASVTPDELRLLCQGIRAIELALGSYDKIVTNSERKNKIVARKSIIAKQNIKQGEVFTLENITTKRPGNGISPMHWYQ
VLGSIAERDFCEDELIYCSNLSMQEL

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=338, Percent_Identity=31.6568047337278, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI21357081, Length=360, Percent_Identity=30.2777777777778, Blast_Score=151, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38825; Mature: 38825

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYIVAEIGCNHNGDPLLAKKMVEQAKAAGVDAVKFQTFKADLLISKYAPKAEYQITQ
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCEEEEC
TGCEESQLEMTRKLELAYDDFIGLSQYAKSLGLDVFSTPFDFDSIDFLASLKQRIWKIPS
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
GELLNLPYLEKIARLDITDKKIIISTGMATLDEINMALHVLHNNGVKASDITILHCNTEY
CCEECCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHEEEEEECCCCCCCCEEEEEECCCC
PTPYSDVNLNTLSSFKNIFKEYQIGFSDHSPGYFSGIAAVPYGICFIEKHFTLNKEFPGP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEEEEEEECCEECCCCCCC
DHKASVTPDELRLLCQGIRAIELALGSYDKIVTNSERKNKIVARKSIIAKQNIKQGEVFT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEE
LENITTKRPGNGISPMHWYQVLGSIAERDFCEDELIYCSNLSMQEL
ECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHCC
>Mature Secondary Structure
MNKVYIVAEIGCNHNGDPLLAKKMVEQAKAAGVDAVKFQTFKADLLISKYAPKAEYQITQ
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCEEEEC
TGCEESQLEMTRKLELAYDDFIGLSQYAKSLGLDVFSTPFDFDSIDFLASLKQRIWKIPS
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
GELLNLPYLEKIARLDITDKKIIISTGMATLDEINMALHVLHNNGVKASDITILHCNTEY
CCEECCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHEEEEEECCCCCCCCEEEEEECCCC
PTPYSDVNLNTLSSFKNIFKEYQIGFSDHSPGYFSGIAAVPYGICFIEKHFTLNKEFPGP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEEEEEEECCEECCCCCCC
DHKASVTPDELRLLCQGIRAIELALGSYDKIVTNSERKNKIVARKSIIAKQNIKQGEVFT
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEE
LENITTKRPGNGISPMHWYQVLGSIAERDFCEDELIYCSNLSMQEL
ECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]