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The map label for this gene is nrdR

Identifier: 238918988

GI number: 238918988

Start: 1053101

End: 1053550

Strand: Direct

Name: nrdR

Synonym: NT01EI_1055

Alternate gene names: 238918988

Gene position: 1053101-1053550 (Clockwise)

Preceding gene: 238918987

Following gene: 238918989

Centisome position: 27.62

GC content: 54.22

Gene sequence:

>450_bases
ATGCACTGTCCGTTTTGTTCCGCTGTCGATACCAAGGTCATTGATTCGCGTCTGGTGGGCGATGGCTCACAGGTGCGCCG
CCGTCGCCAGTGTCTGGTTTGCAATGAACGATTTACCACCTTTGAAGTGGCTGAACTGGTGATGCCACGGGTGGTCAAGA
GCAACGGTGTGCGGGAGCCTTTCAATGAGGATAAGCTGCGCAGCGGCATGCTGAAAGCACTCGAAAAGCGGCCGGTGAAC
TCCGACGATGTCGAGATGGCTATCAGCCATATTAAATCCCAGCTACGTGCCACCGGTGAGCGTGAGGTTGCGACCAAGAT
GGTCGGTAATCTGGTGATGGATGCGCTGAAGAAGCTCGATAAGGTGGCCTACATTCGTTTTGCCTCTGTATATCGCAGTT
TTGAGGATGTACGGGAGTTTGGCGAAGAGATCGCCCGTTTGCAGGAGTAG

Upstream 100 bases:

>100_bases
CGGTTGTGTGATTTTCCATGCAAACGAAGGCGCGGCTCCCTTTGTTGTCGGCGAGCTTGGGGGTACACTATGGCGACCCC
GAAGCTGTCCAGGAAGAGTT

Downstream 100 bases:

>100_bases
CGCATTCAGCGTAGGAACCGTGATGATGATGTCTGCAGTCCATTCCGATGAATTTTACATGGCGCGCGCCTTTGAGCTGG
CGCGCCGTGGCCGCTTTACC

Product: NrdR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCSAVDTKVIDSRLVGDGSQVRRRRQCLVCNERFTTFEVAELVMPRVVKSNGVREPFNEDKLRSGMLKALEKRPVN
SDDVEMAISHIKSQLRATGEREVATKMVGNLVMDALKKLDKVAYIRFASVYRSFEDVREFGEEIARLQE

Sequences:

>Translated_149_residues
MHCPFCSAVDTKVIDSRLVGDGSQVRRRRQCLVCNERFTTFEVAELVMPRVVKSNGVREPFNEDKLRSGMLKALEKRPVN
SDDVEMAISHIKSQLRATGEREVATKMVGNLVMDALKKLDKVAYIRFASVYRSFEDVREFGEEIARLQE
>Mature_149_residues
MHCPFCSAVDTKVIDSRLVGDGSQVRRRRQCLVCNERFTTFEVAELVMPRVVKSNGVREPFNEDKLRSGMLKALEKRPVN
SDDVEMAISHIKSQLRATGEREVATKMVGNLVMDALKKLDKVAYIRFASVYRSFEDVREFGEEIARLQE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=149, Percent_Identity=88.5906040268456, Blast_Score=276, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_EDWI9 (C5BCH3)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002932502.1
- GeneID:   7959438
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1055
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17026; Mature: 17026

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCSAVDTKVIDSRLVGDGSQVRRRRQCLVCNERFTTFEVAELVMPRVVKSNGVREP
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
FNEDKLRSGMLKALEKRPVNSDDVEMAISHIKSQLRATGEREVATKMVGNLVMDALKKLD
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDVREFGEEIARLQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHCPFCSAVDTKVIDSRLVGDGSQVRRRRQCLVCNERFTTFEVAELVMPRVVKSNGVREP
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
FNEDKLRSGMLKALEKRPVNSDDVEMAISHIKSQLRATGEREVATKMVGNLVMDALKKLD
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KVAYIRFASVYRSFEDVREFGEEIARLQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA