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The map label for this gene is degS [H]

Identifier: 238917971

GI number: 238917971

Start: 2134100

End: 2135116

Strand: Reverse

Name: degS [H]

Synonym: EUBELI_02061

Alternate gene names: 238917971

Gene position: 2135116-2134100 (Counterclockwise)

Preceding gene: 238917973

Following gene: 238917970

Centisome position: 99.58

GC content: 23.5

Gene sequence:

>1017_bases
ATGTCTGATTCGTGTAAAAAATATGTTGATAGTGAATATAAATTATTAAAAGATAAGTTAAATGATATTGAAAGTAAAAT
TCGGTCATATAATATTGAATTGAAGACAATAGATAATAATATTAAAAAATTTAATAAAGAAAAAGACTGGACCGAAGATG
TATTTCATTCAGTTACTTCTTTAAAAGAAAATTCAAATGTAACAATTAAAACATTTCAAAACAGGAAAACTGATTTATTA
CAACTTATATCAGATTTATCTACAGAAAAACAAATAGTAACAGAAAAAATTGAAATGTTAAACAACATTTTACAGGAAGA
TGTATCAGATAATGTTTCACATGAAACATTAAACATAAATCAGAATGATTCTGTTAAATTAATTGATATTATTGAAATGG
ACAGACAAAGAATATCAAGAGATATACATGATAGTGTTGTTCAAAATTTAACAGCATTAATACATAAACAGGAATTTATA
TATCAAATAGCTGATAAAGATATTAATAGAGGAAAATTAGAAATTAACAACTCTATTAATTTAATAAAAGATTCAATAAA
TGAATTGAGAAATATTATATATCAGCTGCGGCCGATGAGTATAGATGATTTAGGCTTTAAAAATGCATTAACACACATGT
TAGATAAATTTGACCGAGAAAGTGATAATGTAATATATGATTATTCTATAAATTATAATGATGATATTACTATTAATTCA
ACAATTACAATTTCAATACTTAGAATTATTAATGAGTTAAACAGTAATGCAATTAAGTATTCAGGATGTACCAATATATA
TGTTAATGTAGAATTAGATATGAAAAACAATTGCATCATAGTAAATTTTAAAGATGATGGATGTGGCTTTGATTTTGAAA
ATATACTATATGACAGGGATAAACATTCTGGATTTGGAATGGCTATGTTAAAAGAAAGAGTTTCATTGTTAAAAGGAACA
ATACAATATTCTAATAATAATGGCTCACAGTTTTTAATTAATATTCCAGTGTGGTGA

Upstream 100 bases:

>100_bases
TTTAAGTAATAGTTTTAATTAGTCATAGTTTTATATAATAATATCTATATGTATAATGATTATTATATAAAACTAGTATA
TAAATATTGATGGGGTAAAA

Downstream 100 bases:

>100_bases
GGAGGACTTAACAATGGCAATTAATGTTTTACTGGCCGATGACCATAAGATGGTCAGAGAAGGATTAAAACAATTATTGG
AAATAGATTCTGAGATTAAG

Product: two-component system NarL family sensor histidine kinase DegS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSDSCKKYVDSEYKLLKDKLNDIESKIRSYNIELKTIDNNIKKFNKEKDWTEDVFHSVTSLKENSNVTIKTFQNRKTDLL
QLISDLSTEKQIVTEKIEMLNNILQEDVSDNVSHETLNINQNDSVKLIDIIEMDRQRISRDIHDSVVQNLTALIHKQEFI
YQIADKDINRGKLEINNSINLIKDSINELRNIIYQLRPMSIDDLGFKNALTHMLDKFDRESDNVIYDYSINYNDDITINS
TITISILRIINELNSNAIKYSGCTNIYVNVELDMKNNCIIVNFKDDGCGFDFENILYDRDKHSGFGMAMLKERVSLLKGT
IQYSNNNGSQFLINIPVW

Sequences:

>Translated_338_residues
MSDSCKKYVDSEYKLLKDKLNDIESKIRSYNIELKTIDNNIKKFNKEKDWTEDVFHSVTSLKENSNVTIKTFQNRKTDLL
QLISDLSTEKQIVTEKIEMLNNILQEDVSDNVSHETLNINQNDSVKLIDIIEMDRQRISRDIHDSVVQNLTALIHKQEFI
YQIADKDINRGKLEINNSINLIKDSINELRNIIYQLRPMSIDDLGFKNALTHMLDKFDRESDNVIYDYSINYNDDITINS
TITISILRIINELNSNAIKYSGCTNIYVNVELDMKNNCIIVNFKDDGCGFDFENILYDRDKHSGFGMAMLKERVSLLKGT
IQYSNNNGSQFLINIPVW
>Mature_337_residues
SDSCKKYVDSEYKLLKDKLNDIESKIRSYNIELKTIDNNIKKFNKEKDWTEDVFHSVTSLKENSNVTIKTFQNRKTDLLQ
LISDLSTEKQIVTEKIEMLNNILQEDVSDNVSHETLNINQNDSVKLIDIIEMDRQRISRDIHDSVVQNLTALIHKQEFIY
QIADKDINRGKLEINNSINLIKDSINELRNIIYQLRPMSIDDLGFKNALTHMLDKFDRESDNVIYDYSINYNDDITINST
ITISILRIINELNSNAIKYSGCTNIYVNVELDMKNNCIIVNFKDDGCGFDFENILYDRDKHSGFGMAMLKERVSLLKGTI
QYSNNNGSQFLINIPVW

Specific function: Member of the two-component regulatory system degS/degU. Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39291; Mature: 39160

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSCKKYVDSEYKLLKDKLNDIESKIRSYNIELKTIDNNIKKFNKEKDWTEDVFHSVTS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHCCCCCHHHHHHHHHHH
LKENSNVTIKTFQNRKTDLLQLISDLSTEKQIVTEKIEMLNNILQEDVSDNVSHETLNIN
HCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
QNDSVKLIDIIEMDRQRISRDIHDSVVQNLTALIHKQEFIYQIADKDINRGKLEINNSIN
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHH
LIKDSINELRNIIYQLRPMSIDDLGFKNALTHMLDKFDRESDNVIYDYSINYNDDITINS
HHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECC
TITISILRIINELNSNAIKYSGCTNIYVNVELDMKNNCIIVNFKDDGCGFDFENILYDRD
HHHHHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHCCC
KHSGFGMAMLKERVSLLKGTIQYSNNNGSQFLINIPVW
CCCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCC
>Mature Secondary Structure 
SDSCKKYVDSEYKLLKDKLNDIESKIRSYNIELKTIDNNIKKFNKEKDWTEDVFHSVTS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHCCCCCHHHHHHHHHHH
LKENSNVTIKTFQNRKTDLLQLISDLSTEKQIVTEKIEMLNNILQEDVSDNVSHETLNIN
HCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
QNDSVKLIDIIEMDRQRISRDIHDSVVQNLTALIHKQEFIYQIADKDINRGKLEINNSIN
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHH
LIKDSINELRNIIYQLRPMSIDDLGFKNALTHMLDKFDRESDNVIYDYSINYNDDITINS
HHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECC
TITISILRIINELNSNAIKYSGCTNIYVNVELDMKNNCIIVNFKDDGCGFDFENILYDRD
HHHHHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHCCC
KHSGFGMAMLKERVSLLKGTIQYSNNNGSQFLINIPVW
CCCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3141378; 3141377; 9384377; 3136143 [H]