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The map label for this gene is 238917857

Identifier: 238917857

GI number: 238917857

Start: 2006230

End: 2006709

Strand: Reverse

Name: 238917857

Synonym: EUBELI_01938

Alternate gene names: NA

Gene position: 2006709-2006230 (Counterclockwise)

Preceding gene: 238917858

Following gene: 238917855

Centisome position: 93.59

GC content: 37.71

Gene sequence:

>480_bases
ATGGGCGATAAGAGAAAAGATTATATATCATGGGATGAATATTTCATGGGAATTGCAACACTTTCCGGTATGAGGTCAAA
GGATCCTAATACACAGGTTGGTGCGTGTATAGTAAGTCAGGATAATAAGATATTATCCATGGGGTATAACGGACTTCCAA
GGGGCTGTTCTGATGATGAGTTTCCATGGAACAGAGATGGCGAAGATAATAAGTATTTTTACACAACTCATAGTGAGCTT
AATGCAATTCTTAATTACAGAGGCGGAAGCCTTGATAATGCCAAGCTTTATGTTACACTTTTTCCATGTAACGAATGTGC
TAAGGCAATTATTCAGGCAGGAATTAAGACTGTTGTATATGACTGTGACAAATATGCAGATACTGCATCTGTAATTGCAT
CAAAGAGAATGCTTAATGCCGCAGGTGTCAGATATTACAAGTATGAAAGAACAGGTCGCACAATAACAATTGACATGTAA

Upstream 100 bases:

>100_bases
ACCAGAGCTTGCTTTCAGAATAGCAGATACATTTTTAGATTCCAAGTTTTCTAATGATGAGAGACATATAAGAAGAATCA
GTATGTTAGAGGATTAATAA

Downstream 100 bases:

>100_bases
AAAGGGGTCTGGAAACGAATAAGGTTTCCAGACCCTTTAGAGCTTGTTATTCATGAGATTCAAGAATCCTGATGTATTCA
TTAAAGGTTCCGTTATAGAT

Product: dCMP deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MGDKRKDYISWDEYFMGIATLSGMRSKDPNTQVGACIVSQDNKILSMGYNGLPRGCSDDEFPWNRDGEDNKYFYTTHSEL
NAILNYRGGSLDNAKLYVTLFPCNECAKAIIQAGIKTVVYDCDKYADTASVIASKRMLNAAGVRYYKYERTGRTITIDM

Sequences:

>Translated_159_residues
MGDKRKDYISWDEYFMGIATLSGMRSKDPNTQVGACIVSQDNKILSMGYNGLPRGCSDDEFPWNRDGEDNKYFYTTHSEL
NAILNYRGGSLDNAKLYVTLFPCNECAKAIIQAGIKTVVYDCDKYADTASVIASKRMLNAAGVRYYKYERTGRTITIDM
>Mature_158_residues
GDKRKDYISWDEYFMGIATLSGMRSKDPNTQVGACIVSQDNKILSMGYNGLPRGCSDDEFPWNRDGEDNKYFYTTHSELN
AILNYRGGSLDNAKLYVTLFPCNECAKAIIQAGIKTVVYDCDKYADTASVIASKRMLNAAGVRYYKYERTGRTITIDM

Specific function: Unknown

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=159, Percent_Identity=53.4591194968553, Blast_Score=182, Evalue=9e-47,
Organism=Homo sapiens, GI61742821, Length=159, Percent_Identity=53.4591194968553, Blast_Score=182, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17557019, Length=134, Percent_Identity=48.5074626865672, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321938, Length=157, Percent_Identity=35.031847133758, Blast_Score=78, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24667298, Length=164, Percent_Identity=55.4878048780488, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24667302, Length=164, Percent_Identity=55.4878048780488, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 17926; Mature: 17795

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDKRKDYISWDEYFMGIATLSGMRSKDPNTQVGACIVSQDNKILSMGYNGLPRGCSDDE
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCC
FPWNRDGEDNKYFYTTHSELNAILNYRGGSLDNAKLYVTLFPCNECAKAIIQAGIKTVVY
CCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHCHHHEEE
DCDKYADTASVIASKRMLNAAGVRYYKYERTGRTITIDM
CCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEC
>Mature Secondary Structure 
GDKRKDYISWDEYFMGIATLSGMRSKDPNTQVGACIVSQDNKILSMGYNGLPRGCSDDE
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCC
FPWNRDGEDNKYFYTTHSELNAILNYRGGSLDNAKLYVTLFPCNECAKAIIQAGIKTVVY
CCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHCHHHEEE
DCDKYADTASVIASKRMLNAAGVRYYKYERTGRTITIDM
CCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8329441 [H]